miRBase entry: mmu-mir-149

Stem-loop mmu-mir-149


Accession
MI0000171
Symbol
MGI: Mir149
Description
Mus musculus mmu-mir-149 precursor miRNA
Gene family
MIPF0000274; mir-149

Literature search
30 open access papers mention mmu-mir-149
(324 sentences)

Sequence

52600 reads, 274 reads per million, 86 experiments
ggcUCUGGCUCCGUGUCUUCACUCCCguguuuguccgaggaggGAGGGAGGGACGGGGGCGGUGCu
(((.(((.((((((.(((((.(((((.(.((.....)).).)))))))))).)))))).))).)))

Structure
   U   G      G     A     g g  u 
ggc CUG CUCCGU UCUUC CUCCC u uu g
||| ||| |||||| ||||| ||||| | || u
uCG GGC GGGGCA GGAGG GAGgg g ag c
   U   G      G     -     a g  c 


Annotation confidence High
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Comments
The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context
chr1: 92850378-92850443 [+]

Database links

Mature mmu-miR-149-5p

Accession MIMAT0000159
Description Mus musculus mmu-miR-149-5p mature miRNA
Sequence 4 - UCUGGCUCCGUGUCUUCACUCCC - 26
Evidence experimental
cloned [1-2], Illumina [3-4]
Database links
Predicted targets

Mature mmu-miR-149-3p

Accession MIMAT0016990
Description Mus musculus mmu-miR-149-3p mature miRNA
Sequence 44 - GAGGGAGGGACGGGGGCGGUGC - 65
Evidence experimental
Illumina [4]
Database links
Predicted targets

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 12007417
    Identification of tissue-specific microRNAs from mouse
    "Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T"
    "Curr Biol (2002) 12:735-739

  3. PubMed ID: 20215419
    MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
    "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
    "Mol Hum Reprod (2010) 16:463-471

  4. PubMed ID: 20413612
    Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
    "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
    "Genes Dev (2010) 24:992-1009