miRBase entry: hsa-mir-139

Stem-loop hsa-mir-139


Accession
MI0000261
Symbol
HGNC: MIR139
Description
Homo sapiens hsa-mir-139 precursor miRNA
Gene family
MIPF0000117; mir-139

Literature search
116 open access papers mention hsa-mir-139
(670 sentences)

Sequence

70532 reads, 547 reads per million, 132 experiments
guguauUCUACAGUGCACGUGUCUCCAGUguggcucggaggcUGGAGACGCGGCCCUGUUGGAGUaac
...((((((((((.((.((((((((((((.(.......).)))))))))))))).))).)))))))..

Structure
gug       -   U  A            g gg 
   uauUCUA CAG GC CGUGUCUCCAGU u  c
   ||||||| ||| || |||||||||||| |  u
   aUGAGGU GUC CG GCGCAGAGGUcg a  c
-ca       U   C  -            g gg 


Annotation confidence High
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Comments
The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context
chr11: 72615063-72615130 [-]

Disease association
hsa-mir-139 is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature hsa-miR-139-5p

Accession MIMAT0000250
Description Homo sapiens hsa-miR-139-5p mature miRNA
Sequence 7 - UCUACAGUGCACGUGUCUCCAGU - 29
Evidence experimental
cloned [2]
Database links
Predicted targets

Mature hsa-miR-139-3p

Accession MIMAT0004552
Description Homo sapiens hsa-miR-139-3p mature miRNA
Sequence 43 - UGGAGACGCGGCCCUGUUGGAGU - 65
Evidence experimental
cloned [2]
Database links
Predicted targets

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 12007417
    Identification of tissue-specific microRNAs from mouse
    "Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T"
    "Curr Biol (2002) 12:735-739