Stem-loop hsa-mir-137

Accession

MI0000454

Symbol

HGNC: MIR137

Description

Homo sapiens hsa-mir-137 precursor miRNA mir-137

Gene
family

RF00694; mir-137

Literature search

199 open access papers mention hsa-mir-137
(1747 sentences)

Sequence

102894 reads, 383 reads per million, 71 experiments

gguccucugacucucuucggugACGGGUAUUCUUGGGUGGAUAAUacggauuacguugUUAUUGCUUAAGAAUACGCGUAGucgaggagaguaccagcggca
.(.((.((((((((((((((..(((.(((((((((((((.((((((((.....)).))))))))))))))))))).)))..)))))))))))..))).))).

Structure

g u  u   --           ug   G             G      -  g 
 g cc cug  acucucuucgg  ACG GUAUUCUUGGGUG AUAAUa cg a
 | || |||  |||||||||||  ||| ||||||||||||| |||||| || u
 c gg gac  ugagaggagcu  UGC CAUAAGAAUUCGU UAUUgu gc u
a -  c   ca           GA   G             -      u  a 

Annotation confidence High

Comments

This miRNA sequence is predicted based on homology to a verified miRNA from mouse [1], later verified in human [2].

Genome context

chr1: 98046070-98046171 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from hsa-mir-137

Disease association

hsa-mir-137 is associated with one or more human diseases in the Human microRNA Disease Database

Biological pathways

hsa-mir-137 is involved in one or more biological pathways:

(Source: Reactome)

Biological reactions

hsa-mir-137 is involved in one or more regulation/signalling events:

(Source: Reactome)

Mature hsa-miR-137-3p

• Accession: MIMAT0000429
• Description: Homo sapiens hsa-miR-137-3p mature miRNA
• Sequence: 59 - UUAUUGCUUAAGAAUACGCGUAG - 81
• Evidence: experimental ; cloned [2]

Mature hsa-miR-137-5p

• Accession: MIMAT0037310
• Description: Homo sapiens hsa-miR-137-5p mature miRNA
• Sequence: 23 - ACGGGUAUUCUUGGGUGGAUAAU - 45
• Evidence: not_experimental

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 12007417
   Identification of tissue-specific microRNAs from mouse
   "Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T"
   "Curr Biol (2002) 12:735-739