Stem-loop hsa-mir-144

Accession

MI0000460

Symbol

HGNC: MIR144

Description

Homo sapiens hsa-mir-144 precursor miRNA mir-144

Gene
family

RF00682; mir-144

Literature search

164 open access papers mention hsa-mir-144
(963 sentences)

Sequence

120704 reads, 740 reads per million, 101 experiments

uggggcccuggcugGGAUAUCAUCAUAUACUGUAAGuuugcgaugagacacUACAGUAUAGAUGAUGUACUaguccgggcaccccc
.(((((((.((((((.((((((((.(((((((((.((((......))))..))))))))))))))))).)))))).)))).)))..

Structure

-u   -    u      G        A         -A    gc 
  ggg gccc ggcugG AUAUCAUC UAUACUGUA  Guuu  g
  ||| |||| |||||| |||||||| |||||||||  ||||   
  ccc cggg cugaUC UGUAGUAG AUAUGACAU  caga  a
cc   a    c      A        -         ca    gu 

Annotation confidence High

Comments

This miRNA sequence is predicted based on homology to a verified miRNA from mouse [1]. The expression of this miRNA has not been verified in human. The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

chr17: 28861533-28861618 [-]

Clustered miRNAs

3 other miRNAs are < 10 kb from hsa-mir-144

Disease association

hsa-mir-144 is associated with one or more human diseases in the Human microRNA Disease Database

Biological pathways

hsa-mir-144 is involved in one or more biological pathways:

(Source: Reactome)

Biological reactions

hsa-mir-144 is involved in one or more regulation/signalling events:

(Source: Reactome)

Mature hsa-miR-144-5p

• Accession: MIMAT0004600
• Description: Homo sapiens hsa-miR-144-5p mature miRNA
• Sequence: 15 - GGAUAUCAUCAUAUACUGUAAG - 36
• Evidence: experimental ; cloned [2]

Mature hsa-miR-144-3p

• Accession: MIMAT0000436
• Description: Homo sapiens hsa-miR-144-3p mature miRNA
• Sequence: 52 - UACAGUAUAGAUGAUGUACU - 71
• Evidence: experimental ; cloned [2]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 12007417
   Identification of tissue-specific microRNAs from mouse
   "Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T"
   "Curr Biol (2002) 12:735-739