miRBase entry: mmu-mir-28a

Stem-loop mmu-mir-28a


Accession
MI0000690
Symbol
MGI: Mir28a
Description
Mus musculus mmu-mir-28a precursor miRNA
Gene family
MIPF0000057; mir-28

Literature search
22 open access papers mention mmu-mir-28a
(164 sentences)

Sequence

134288 reads, 600 reads per million, 106 experiments
ggucccuaccuucAAGGAGCUCACAGUCUAUUGAGuugccuuucugauucuccCACUAGAUUGUGAGCUGCUGGAgggcaggcacu
(((.(((.(((((.((.(((((((((((((..(((((........)))))......))))))))))))).)).))))).))).)))

Structure
   c   a     A  G             ----UU     gcc 
ggu ccu ccuuc AG AGCUCACAGUCUA      GAGuu   u
||| ||| ||||| || |||||||||||||      |||||    
uca gga gggAG UC UCGAGUGUUAGAU      cuuag   u
   c   c     G  G             CACccu     ucu 


Annotation confidence High
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Comments
Mouse mir-28 is predicted [2] based on homology to a cloned miR from human (MIR:MI0000086) [1]. Its expression was later verified by cloning [3].

Genome context
chr16: 24827855-24827940 [+]

Database links

Mature mmu-miR-28a-5p

Accession MIMAT0000653
Description Mus musculus mmu-miR-28a-5p mature miRNA
Sequence 14 - AAGGAGCUCACAGUCUAUUGAG - 35
Evidence experimental
cloned [3], Illumina [4-5]
Database links
Predicted targets

Mature mmu-miR-28a-3p

Accession MIMAT0004661
Description Mus musculus mmu-miR-28a-3p mature miRNA
Sequence 54 - CACUAGAUUGUGAGCUGCUGGA - 75
Evidence experimental
cloned [3], Illumina [4-5]
Database links
Predicted targets

References

  1. PubMed ID: 11679670
    Identification of novel genes coding for small expressed RNAs
    "Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T"
    "Science (2001) 294:853-858

  2. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  3. PubMed ID: 20215419
    MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
    "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
    "Mol Hum Reprod (2010) 16:463-471

  4. PubMed ID: 20413612
    Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
    "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
    "Genes Dev (2010) 24:992-1009

  5. PubMed ID: 15634332
    New human and mouse microRNA genes found by homology search
    "Weber MJ"
    "FEBS J (2005) 272:59-73