miRBase entry: rno-mir-124-3

Stem-loop rno-mir-124-3


Accession
MI0000892
Description
Rattus norvegicus rno-mir-124-3 precursor miRNA
Gene family
MIPF0000021; mir-124

Literature search
86 open access papers mention rno-mir-124-3
(387 sentences)

Sequence

1003543 reads, 6264 reads per million, 365 experiments
ugagggccccucugCGUGUUCACAGCGGACCUUGAUuuaaugucuauacaauUAAGGCACGCGGUGAAUGCCaagagaggcgccucc
.(((((((.((((..((((((((.(((..((((((((............))))))))..))).))))))))..)))).))).)))).

Structure
u    -   c    gC        A   GA        uaaug 
 gagg gcc cucu  GUGUUCAC GCG  CCUUGAUu     u
 |||| ||| ||||  |||||||| |||  ||||||||      
 cucc cgg gaga  CGUAAGUG CGC  GGAAUuaa     c
c    g   a    aC        G   AC        cauau 


Annotation confidence High
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Comments
The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [3]. The ends of the miRNA may be offset with respect to previous annotations.

Genome context
chr3: 176406205-176406291 [+]

Database links

Mature rno-miR-124-5p

Accession MIMAT0004728
Description Rattus norvegicus rno-miR-124-5p mature miRNA
Sequence 15 - CGUGUUCACAGCGGACCUUGAU - 36
Evidence experimental
cloned [3], SOLiD [4]

Mature rno-miR-124-3p

Accession MIMAT0000828
Description Rattus norvegicus rno-miR-124-3p mature miRNA
Sequence 53 - UAAGGCACGCGGUGAAUGCC - 72
Evidence experimental
cloned [1-3], Northern [1], SOLiD [4]

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 14691248
    Identification of many microRNAs that copurify with polyribosomes in mammalian neurons
    "Kim J, Krichevsky A, Grad Y, Hayes GD, Kosik KS, Church GM, Ruvkun G"
    "Proc Natl Acad Sci U S A (2004) 101:360-365

  3. PubMed ID: 20403161
    Small RNA expression and strain specificity in the rat
    Linsen SE, de Wit E, de Bruijn E, Cuppen E
    BMC Genomics (2010) 11:249

  4. PubMed ID: 15345052
    Microarray analysis of microRNA expression in the developing mammalian brain
    Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Sestan N, Rakic P, Constantine-Paton M, Horvitz HR
    Genome Biol (2004) 5:R68