Stem-loop rno-mir-127

Accession

MI0000899

Description

Rattus norvegicus rno-mir-127 precursor miRNA

Literature search

26 open access papers mention rno-mir-127
(403 sentences)

Sequence

24972592 reads, 17452 reads per million, 494 experiments

uuugaucacugucuccagccugCUGAAGCUCAGAGGGCUCUGAUUcagaaagaucaUCGGAUCCGUCUGAGCUUGGCUggucggaagucucaucauc
..((((.(((...(((.(((.(((.(((((((((.((.((((((((.....))..)))))).)).)))))))))))).))).))))))...))))..

Structure

uu    --c   guc   a   u   G         G  C      --  a 
  ugau   acu   ucc gcc gCU AAGCUCAGA GG UCUGAU  Uc g
  ||||   |||   ||| ||| ||| ||||||||| || ||||||  || a
  acua   uga   agg ugg CGG UUCGAGUCU CC AGGCUa  ag a
cu    cuc   ---   c   U   -         G  U      cu  a 

Annotation confidence Medium

Genome context

chr6: 133713430-133713526 [+]

Clustered miRNAs

11 other miRNAs are < 10 kb from rno-mir-127

Mature rno-miR-127-5p

• Accession: MIMAT0017117
• Description: Rattus norvegicus rno-miR-127-5p mature miRNA
• Sequence: 23 - CUGAAGCUCAGAGGGCUCUGAUU - 45
• Evidence: experimental ; SOLiD [4]

Mature rno-miR-127-3p

• Accession: MIMAT0000833
• Description: Rattus norvegicus rno-miR-127-3p mature miRNA
• Sequence: 57 - UCGGAUCCGUCUGAGCUUGGCU - 78
• Evidence: experimental ; cloned [1-3], SOLiD [4]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 14691248
   Identification of many microRNAs that copurify with polyribosomes in mammalian neurons
   "Kim J, Krichevsky A, Grad Y, Hayes GD, Kosik KS, Church GM, Ruvkun G"
   "Proc Natl Acad Sci U S A (2004) 101:360-365


3. PubMed ID: 20403161
   Small RNA expression and strain specificity in the rat
   Linsen SE, de Wit E, de Bruijn E, Cuppen E
   BMC Genomics (2010) 11:249


4. PubMed ID: 15345052
   Microarray analysis of microRNA expression in the developing mammalian brain
   Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Sestan N, Rakic P, Constantine-Paton M, Horvitz HR
   Genome Biol (2004) 5:R68