miRBase entry: rno-mir-139

Stem-loop rno-mir-139


Accession
MI0000913
Description
Rattus norvegicus rno-mir-139 precursor miRNA
Gene family
MIPF0000117; mir-139

Literature search
21 open access papers mention rno-mir-139
(337 sentences)

Sequence

110411 reads, 131 reads per million, 481 experiments
guguauUCUACAGUGCACGUGUCUCCAGuguggcucggaggcUGGAGACGCGGCCCUGUUGGAGuaac
...((((((((((.((.((((((((((((.(.......).)))))))))))))).))).)))))))..

Structure
gug       -   U  A            g gg 
   uauUCUA CAG GC CGUGUCUCCAGu u  c
   ||||||| ||| || |||||||||||| |  u
   auGAGGU GUC CG GCGCAGAGGUcg a  c
-ca       U   C  -            g gg 


Annotation confidence High
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Comments
The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [3]. The ends of the miRNA may be offset with respect to previous annotations.

Genome context
chr1: 166589545-166589612 [+]

Database links

Mature rno-miR-139-5p

Accession MIMAT0000845
Description Rattus norvegicus rno-miR-139-5p mature miRNA
Sequence 7 - UCUACAGUGCACGUGUCUCCAG - 28
Evidence experimental
cloned [1-3], SOLiD [4]

Mature rno-miR-139-3p

Accession MIMAT0004735
Description Rattus norvegicus rno-miR-139-3p mature miRNA
Sequence 43 - UGGAGACGCGGCCCUGUUGGAG - 64
Evidence experimental
cloned [3], SOLiD [4]

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 16766679
    Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes
    "Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H"
    "Genes Dev (2006) 20:1732-1743

  3. PubMed ID: 20403161
    Small RNA expression and strain specificity in the rat
    Linsen SE, de Wit E, de Bruijn E, Cuppen E
    BMC Genomics (2010) 11:249

  4. PubMed ID: 15345052
    Microarray analysis of microRNA expression in the developing mammalian brain
    Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Sestan N, Rakic P, Constantine-Paton M, Horvitz HR
    Genome Biol (2004) 5:R68