miRBase entry: rno-mir-186

Stem-loop rno-mir-186


Accession
MI0000931
Description
Rattus norvegicus rno-mir-186 precursor miRNA
Gene family
MIPF0000109; mir-186

Literature search
15 open access papers mention rno-mir-186
(103 sentences)

Sequence

2025406 reads, 1969 reads per million, 509 experiments
ugcuuacaacuuucCAAAGAAUUCUCCUUUUGGGCUuucucauuuuauuuuaaGCCCAAAGGUGAAUUUUUUGGgaaguuugagcu
.(((((.(((((((((((((((((.(((((.((((((..............))))))))))).)))))))))))))))))))))).

Structure
u     c                 U     U      ucucau 
 gcuua aacuuucCAAAGAAUUC CCUUU GGGCUu      u
 ||||| ||||||||||||||||| ||||| ||||||       
 cgagu uugaagGGUUUUUUAAG GGAAA CCCGaa      u
u     -                 U     -      uuuuau 


Annotation confidence High
Do you think this miRNA is real?
Comments
The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2]. The ends of the miRNA may be offset with respect to previous annotations.

Genome context
chr2: 263873759-263873844 [+]

Database links

Mature rno-miR-186-5p

Accession MIMAT0000863
Description Rattus norvegicus rno-miR-186-5p mature miRNA
Sequence 15 - CAAAGAAUUCUCCUUUUGGGCU - 36
Evidence experimental
cloned [1-3], SOLiD [4]

Mature rno-miR-186-3p

Accession MIMAT0017143
Description Rattus norvegicus rno-miR-186-3p mature miRNA
Sequence 54 - GCCCAAAGGUGAAUUUUUUGG - 74
Evidence experimental
SOLiD [4]

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 16766679
    Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes
    "Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H"
    "Genes Dev (2006) 20:1732-1743

  3. PubMed ID: 20403161
    Small RNA expression and strain specificity in the rat
    Linsen SE, de Wit E, de Bruijn E, Cuppen E
    BMC Genomics (2010) 11:249

  4. PubMed ID: 17805466
    Cloning and identification of novel microRNAs from rat hippocampus
    "He X, Zhang Q, Liu Y, Pan X"
    "Acta Biochim Biophys Sin (Shanghai) (2007) 39:708-714