Stem-loop sequence mmu-mir-431

Accession

MI0001524 (change log)

Symbol

MGI:Mir431

Description

Mus musculus miR-431 stem-loop

Gene family

MIPF0000142; mir-431

Literature search

21 open access papers mention mmu-mir-431
(173 sentences)

Stem-loop

   -----    c       u          c  u a     ----   aca 
5'      cguc ugcgagg gucuugcagg cg c ugcag    gcc   c
        |||| ||||||| |||||||||| || | |||||    |||    
3'      gcag acgcucu cgggacguuc gc g acguu    ugg   u
   cuaca    a       u          u  u g     gcaa   cag 

Deep sequencing

101687 reads, 797 reads per million, 68 experiments

Confidence

Annotation confidence: not enough data

Feedback: Do you believe this miRNA is real?

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [3].

Genome context

• Coordinates (GRCm38; GCA_000001635.2): chr12: 109590447-109590537 [+]
• Overlapping transcripts:

  antisense

  ENSMUST00000149046 ; Rtl1-201; exon 2

Clustered miRNAs

< 10kb from mmu-mir-431

• mmu-mir-337: chr12: 109585789-109585885 [+]
• mmu-mir-3544: chr12: 109585813-109585873 [-]
• mmu-mir-540: chr12: 109586080-109586146 [+]
• mmu-mir-665: chr12: 109586314-109586407 [+]
• mmu-mir-3070-1: chr12: 109587943-109588031 [+]
• mmu-mir-3070-2: chr12: 109588592-109588680 [+]
• mmu-mir-431: chr12: 109590447-109590537 [+]
• mmu-mir-433: chr12: 109591715-109591838 [+]
• mmu-mir-127: chr12: 109592846-109592915 [+]
• mmu-mir-434: chr12: 109594506-109594599 [+]
• mmu-mir-432: chr12: 109594956-109595030 [+]
• mmu-mir-3071: chr12: 109595318-109595397 [-]
• mmu-mir-136: chr12: 109595327-109595388 [+]

Database links

• EntrezGene:Mir431
• MGI:Mir431
• RNAcentral:URS000075DC16_10090
• miRBase Tracker:MI0001524

Mature sequence mmu-miR-431-5p

• Accession: MIMAT0001418
• Previous IDs: mmu-miR-431
• Sequence: 13 - ugucuugcaggccgucaugca - 33
• Deep sequencing: 92757 reads, 67 experiments
• Evidence: experimental; PCR [1], cloned [2-3], insitu [2], Northern [2], Illumina [4-5]
• Database links:
  • RNAcentral:URS000043908D_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-431-5p
  • miRDB:mmu-miR-431-5p
  • microrna.org:mmu-miR-431-5p

Mature sequence mmu-miR-431-3p

• Accession: MIMAT0004753
• Previous IDs: mmu-miR-431*
• Sequence: 56 - caggucgucuugcagggcuucu - 77
• Deep sequencing: 8919 reads, 57 experiments
• Evidence: experimental; cloned [3], Illumina [4-5]
• Database links:
  • RNAcentral:URS0000086A4D_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-431-3p
  • miRDB:mmu-miR-431-3p
  • microrna.org:mmu-miR-431-3p

References

1. PMID:15854907 "RNAi-mediated allelic trans-interaction at the imprinted Rtl1/Peg11 locus" Davis E, Caiment F, Tordoir X, Cavaille J, Ferguson-Smith A, Cockett N, Georges M, Charlier C Curr Biol. 15:743-749(2005).
2. PMID:16566924 "Identification of new central nervous system specific mouse microRNAs" Wheeler G, Ntounia-Fousara S, Granda B, Rathjen T, Dalmay T FEBS Lett. 580:2195-2200(2006).
3. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
4. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
5. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).