miRBase entry: hsa-mir-448

Stem-loop hsa-mir-448


Accession
MI0001637
Symbol
HGNC: MIR448
Description
Homo sapiens hsa-mir-448 precursor miRNA
Gene family
MIPF0000149; mir-448

Literature search
36 open access papers mention hsa-mir-448
(236 sentences)

Sequence

34 reads, 6 reads per million, 12 experiments
gccgggagguugaacauccugcauagugcugccaggaaaucccuauuucauauaagagggggcuggcuggUUGCAUAUGUAGGAUGUCCCAUcucccagcccacuucguca
((.(((((((.(.((((((((((((.(((.(((((....(((((.((......)).))))).....))))).))))))))))))))).).))))))).))...........

Structure
-----------  c       u a            g   u     -gaaa     a  uc 
           gc gggaggu g acauccugcaua ugc gccag     ucccu uu  a
           || ||||||| | |||||||||||| ||| |||||     ||||| ||   
           cg cccucUA C UGUAGGAUGUAU ACG Ugguc     gggga aa  u
acugcuucacc  a       C C            -   U     ggucg     g  ua 


Annotation confidence Not enough data
Do you think this miRNA is real?
Comments
Xie et al. [1] refer to this sequence by the internal identifier MIR64. The sequence is unrelated to C. elegans mir-64 (MIR:MI0000035).

Genome context
chrX: 114823454-114823564 [+]

Disease association
hsa-mir-448 is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature hsa-miR-448

Accession MIMAT0001532
Description Homo sapiens hsa-miR-448 mature miRNA
Sequence 71 - UUGCAUAUGUAGGAUGUCCCAU - 92
Evidence experimental
cloned [1]

References

  1. PubMed ID: 15735639
    Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals
    "Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, Lander ES, Kellis M"
    "Nature (2005) 434:338-345