Stem-loop sequence ptr-mir-127

Accession

MI0002583 (change log)

Description

Pan troglodytes miR-127 stem-loop

Gene family

MIPF0000080; mir-127

Literature search

1 open access papers mention ptr-mir-127
(92 sentences)

Stem-loop

   -----  u   ca   ucu      ugcug         g  c      --  a 
5'      ug gau  cug   ccagcc     aagcucaga gg ucugau  uc g
        || |||  |||   ||||||     ||||||||| || ||||||  || a
3'      ac cug  ggc   ggucgg     uucgagucu cc aggcua  ag a
   cuacu  u   aa   --u      -----         g  u      cu  a 

Confidence

Annotation confidence: not enough data

Feedback: Do you believe this miRNA is real?

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context

• Coordinates (Pan_tro3.0; GCA_000001515.5): chr14: 86127939-86128035 [+]
• Overlapping transcripts:

  antisense

  ENSPTRT00000012391 ; ptr-mir-136-201; exon 2

Clustered miRNAs

< 10kb from ptr-mir-127

• ptr-mir-337: chr14: 86119486-86119577 [+]
• ptr-mir-665: chr14: 86120026-86120096 [+]
• ptr-mir-431: chr14: 86125968-86126080 [+]
• ptr-mir-433: chr14: 86126847-86126938 [+]
• ptr-mir-127: chr14: 86127939-86128035 [+]
• ptr-mir-432: chr14: 86129447-86129539 [+]
• ptr-mir-136: chr14: 86129665-86129746 [+]

Database links

• EntrezGene:MIR127
• miRBase Tracker:MI0002583

Mature sequence ptr-miR-127

• Accession: MIMAT0002282
• Sequence: 57 - ucggauccgucugagcuuggcu - 78
• Evidence: by similarity; MI0000472
• Predicted targets:
  • TargetScanVert:ptr-miR-127

References

1. PMID:15652478 "Phylogenetic shadowing and computational identification of human microRNA genes" Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E Cell. 120:21-24(2005).