Stem-loop mml-mir-105-1

Accession

MI0002750

Description

Macaca mulatta mml-mir-105-1 precursor miRNA

Gene family

MIPF0000074; mir-105

Sequence

6895 reads, 57 reads per million, 8 experiments

ugugcaucguggUCAAAUGCUCAGACUCCUGUGGUggcugcucaugcaccACGGAUGUUUGAGCAUGUGCUAcggugucua
...(((((((((.((.((((((((((..((((((((..........))))))))..)))))))))).)))))))))))...

Structure

ugu         U  A          UC        gcug 
   gcaucgugg CA AUGCUCAGAC  CUGUGGUg    c
   ||||||||| || ||||||||||  ||||||||     
   uguggcAUC GU UACGAGUUUG  GGCAccac    u
auc         -  G          UA        guac 

Annotation confidence High

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context

chrX: 146009447-146009527 [-]

Clustered miRNAs

2 other miRNAs are < 10 kb from mml-mir-105-1

Mature mml-miR-105-5p

• Accession: MIMAT0002454
• Description: Macaca mulatta mml-miR-105-5p mature miRNA
• Sequence: 13 - UCAAAUGCUCAGACUCCUGUGGU - 35
• Evidence: experimental ; Illumina [2]

Mature mml-miR-105-3p

• Accession: MIMAT0026583
• Description: Macaca mulatta mml-miR-105-3p mature miRNA
• Sequence: 51 - ACGGAUGUUUGAGCAUGUGCUA - 72
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 15652478
   Phylogenetic shadowing and computational identification of human microRNA genes
   "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
   "Cell (2005) 120:21-24


2. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45