miRBase entry: mml-mir-124a-1

Stem-loop mml-mir-124a-1


Accession
MI0002766
Description
Macaca mulatta mml-mir-124a-1 precursor miRNA
Gene family
MIPF0000021; mir-124

Literature search
1 open access papers mention mml-mir-124a-1
(2 sentences)

Sequence

386912 reads, 2479 reads per million, 9 experiments
aucaagaucagaggcucugcccuccguGUUCACAGCGGACCUUGAUuuaaugucauacaaUUAAGGCACGCGGUGAAUGCCAagagcggagccuacggcugcacuugaa
.(((((..((((((((((((.((..((((((((.(((..((((((((...........))))))))..))).))))))))..)).)))))))))....)))..))))).

Structure
a     au   ----         c  cc        A   GA        uaau 
 ucaag  cag    aggcucugc cu  guGUUCAC GCG  CCUUGAUu    g
 |||||  |||    ||||||||| ||  |||||||| |||  ||||||||    u
 aguuc  guc    uccgaggcg ga  CGUAAGUG CGC  GGAAUUaa    c
a     ac   ggca         a  AC        G   AC        caua 


Annotation confidence High
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Comments
Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [2]. The expression of this mature miRNA was validated by Miska et al [1].

Genome context
chr8: 62428637-62428745 [+]

Database links

Mature mml-miR-124a-3p

Accession MIMAT0002470
Description Macaca mulatta mml-miR-124a-3p mature miRNA
Sequence 61 - UUAAGGCACGCGGUGAAUGCCA - 82
Evidence experimental
Illumina [2]
Database links
Predicted targets

Mature mml-miR-124a-5p

Accession MIMAT0026585
Description Macaca mulatta mml-miR-124a-5p mature miRNA
Sequence 28 - GUUCACAGCGGACCUUGAU - 46
Evidence experimental
Illumina [2]

References

  1. PubMed ID: 15345052
    Microarray analysis of microRNA expression in the developing mammalian brain
    Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Sestan N, Rakic P, Constantine-Paton M, Horvitz HR
    Genome Biol (2004) 5:R68

  2. PubMed ID: 15652478
    Phylogenetic shadowing and computational identification of human microRNA genes
    "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
    "Cell (2005) 120:21-24

  3. PubMed ID: 23034410
    Birth and expression evolution of mammalian microRNA genes
    "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
    "Genome Res (2013) 23:34-45