miRBase entry: ppy-mir-181a-1

Stem-loop ppy-mir-181a-1

Accession

MI0002935

Description

Pongo pygmaeus ppy-mir-181a-1 precursor miRNA

Gene family

MIPF0000007; mir-181

Sequence

ugaguuuugagguugcuucagugAACAUUCAACGCUGUCGGUGAGUuuggaauuaaaaucaaaACCAUCGACCGUUGAUUGUACCcuauggcuaaccaucaucuacucca
.((((..((((((((((..((.(.(((.((((((..(((((((.((((.((.......)).))))))))))))))))).))).).))..))).)))).)))...))))..

Structure

-u    -uu   -    -   uc  u A   U      CU       A    g  au 
  gagu   uga gguu gcu  ag g ACA UCAACG  GUCGGUG GUuu ga  u
  ||||   ||| |||| |||  || | ||| ||||||  ||||||| |||| ||  a
  cuca   acu ccaa cgg  uc C UGU AGUUGC  CAGCUAC CAaa cu  a
ac    ucu   a    u   ua  C A   U      --       -    a  aa

Annotation confidence Not enough data

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Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context

chr1: 51520574-51520683 [+]

Clustered miRNAs

1 other miRNA is < 10 kb from ppy-mir-181a-1

Name	Accession	Chromosome	Start	End	Strand	Confidence

Database links

Mature ppy-miR-181a-5p

Accession	MIMAT0002626
Description	Pongo pygmaeus ppy-miR-181a-5p mature miRNA
Sequence	24 - AACAUUCAACGCUGUCGGUGAGU - 46
Evidence	not_experimental

Mature ppy-miR-181a-3p

Accession	MIMAT0002627
Description	Pongo pygmaeus ppy-miR-181a-3p mature miRNA
Sequence	64 - ACCAUCGACCGUUGAUUGUACC - 85
Evidence	not_experimental

References

PubMed ID: 15652478
Phylogenetic shadowing and computational identification of human microRNA genes
"Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
"Cell (2005) 120:21-24