Stem-loop sequence hsa-mir-495

Accession

MI0003135 (change log)

Symbol

HGNC:MIR495

Description

Homo sapiens miR-495 stem-loop

Gene family

MIPF0000110; mir-329

Literature search

50 open access papers mention hsa-mir-495
(177 sentences)

Stem-loop

   u      u          u  -       au     - uuu 
5'  gguacc gaaaagaagu gc ccauguu  uuucg c   a
    |||||| |||||||||| || |||||||  ||||| |   u
3'  cuaugg uuuuucuuca cg gguacaa  aaagc g   a
   a      c          -  u       ac     a ugu 

Deep sequencing

20509 reads, 91.3 reads per million, 127 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr14: 101033755-101033836 [+]
• Overlapping transcripts:

  antisense

  OTTHUMT00000414334 ; BEGAIN-007; intron 1

  OTTHUMT00000414329 ; BEGAIN-001; intron 2

  OTTHUMT00000414331 ; BEGAIN-005; intron 2

  OTTHUMT00000414332 ; BEGAIN-003; intron 2

  OTTHUMT00000414335 ; BEGAIN-006; intron 2

  OTTHUMT00000414337 ; BEGAIN-004; intron 2

  ENST00000557378 ; BEGAIN-007; intron 1

  ENST00000443071 ; BEGAIN-201; intron 1

  ENST00000355173 ; BEGAIN-001; intron 2

  ENST00000553553 ; BEGAIN-005; intron 2

  ENST00000556188 ; BEGAIN-003; intron 2

  ENST00000554140 ; BEGAIN-006; intron 2

  ENST00000554747 ; BEGAIN-004; intron 2

Clustered miRNAs

< 10kb from hsa-mir-495

• hsa-mir-299: chr14: 101023794-101023856 [+]
• hsa-mir-380: chr14: 101025017-101025077 [+]
• hsa-mir-1197: chr14: 101025564-101025651 [+]
• hsa-mir-323a: chr14: 101025732-101025817 [+]
• hsa-mir-758: chr14: 101026020-101026107 [+]
• hsa-mir-329-1: chr14: 101026785-101026864 [+]
• hsa-mir-329-2: chr14: 101027100-101027183 [+]
• hsa-mir-494: chr14: 101029634-101029714 [+]
• hsa-mir-1193: chr14: 101030052-101030129 [+]
• hsa-mir-543: chr14: 101031987-101032064 [+]
• hsa-mir-495: chr14: 101033755-101033836 [+]
• hsa-mir-376c: chr14: 101039690-101039755 [+]
• hsa-mir-376a-2: chr14: 101040069-101040148 [+]
• hsa-mir-654: chr14: 101040219-101040299 [+]
• hsa-mir-376b: chr14: 101040436-101040535 [+]
• hsa-mir-376a-1: chr14: 101040782-101040849 [+]
• hsa-mir-300: chr14: 101041363-101041445 [+]
• hsa-mir-1185-1: chr14: 101042977-101043062 [+]

Database links

• EntrezGene:MIR495
• HGNC:MIR495
• RNAcentral:URS000075C517_9606
• miRBase Tracker:MI0003135

Mature sequence hsa-miR-495-5p

• Accession: MIMAT0022924
• Sequence: 14 - gaaguugcccauguuauuuucg - 35
• Deep sequencing: 235 reads, 66 experiments
• Evidence: experimental; SOLiD [3]
• Database links:
  • RNAcentral:URS00004FFC5A_9606
• Predicted targets:
  • TargetScanVert:hsa-miR-495-5p
  • miRDB:hsa-miR-495-5p

Mature sequence hsa-miR-495-3p

• Accession: MIMAT0002817
• Previous IDs: hsa-miR-495
• Sequence: 50 - aaacaaacauggugcacuucuu - 71
• Deep sequencing: 20270 reads, 127 experiments
• Evidence: experimental; array-cloned [1], cloned [2], SOLiD [3]
• Database links:
  • RNAcentral:URS000005A8ED_9606
• Predicted targets:
  • TargetScanVert:hsa-miR-495-3p
  • miRDB:hsa-miR-495-3p
  • microrna.org:hsa-miR-495-3p

References

1. PMID:15965474 "Identification of hundreds of conserved and nonconserved human microRNAs" Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z Nat Genet. 37:766-770(2005).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3. PMID:22282338 "Deep-sequencing of endothelial cells exposed to hypoxia reveals the complexity of known and novel microRNAs" Voellenkle C, Rooij Jv, Guffanti A, Brini E, Fasanaro P, Isaia E, Croft L, David M, Capogrossi MC, Moles A, Felsani A, Martelli F RNA. 18:472-484(2012).