miRBase entry: hsa-mir-512-2

Stem-loop hsa-mir-512-2


Accession
MI0003141
Symbol
HGNC: MIR512-2
Description
Homo sapiens hsa-mir-512-2 precursor miRNA
Gene family
MIPF0000130; mir-506

Literature search
42 open access papers mention hsa-mir-512-2
(256 sentences)

Sequence

259 reads, 18 reads per million, 20 experiments
gguacuucucagucuguggCACUCAGCCUUGAGGGCACUUUCuggugccagaaugaAAGUGCUGUCAUAGCUGAGGUCcaaugacugaggcgagcacc
(((.((((((((((..(((..((((((..(((.(((((((((............))))))))).)))..))))))..)))..)))))))..))).)))

Structure
   a   --       ug   CA      CU   G         uggug 
ggu cuu  cucaguc  ugg  CUCAGC  UGA GGCACUUUC     c
||| |||  |||||||  |||  ||||||  ||| |||||||||      
cca gag  gagucag  acC  GAGUCG  ACU UCGUGAAag     c
   c   cg       ua   UG      AU   G         uaaga 


Annotation confidence High
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Genome context
chr19: 53669157-53669254 [+]
Clustered miRNAs
5 other miRNAs are < 10 kb from hsa-mir-512-2
Name Accession Chromosome Start End Strand Confidence




Disease association
hsa-mir-512-2 is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature hsa-miR-512-5p

Accession MIMAT0002822
Description Homo sapiens hsa-miR-512-5p mature miRNA
Sequence 20 - CACUCAGCCUUGAGGGCACUUUC - 42
Evidence experimental
array-cloned [1]

Mature hsa-miR-512-3p

Accession MIMAT0002823
Description Homo sapiens hsa-miR-512-3p mature miRNA
Sequence 57 - AAGUGCUGUCAUAGCUGAGGUC - 78
Evidence experimental
array-cloned [1], cloned [2]
Database links
Predicted targets

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 15965474
    Identification of hundreds of conserved and nonconserved human microRNAs
    "Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z"
    "Nat Genet (2005) 37:766-770