miRBase entry: hsa-mir-519e

Stem-loop hsa-mir-519e


Accession
MI0003145
Symbol
HGNC: MIR519E
Description
Homo sapiens hsa-mir-519e precursor miRNA
Gene family
MIPF0000020; mir-515

Literature search
24 open access papers mention hsa-mir-519e
(62 sentences)

Sequence

6 reads, 2 reads per million, 4 experiments
ucucaugcagucaUUCUCCAAAAGGGAGCACUUUCuguuugaaagaaaacaAAGUGCCUCCUUUUAGAGUGUUacuguuugaga
(((((.(((((.((.(((.(((((((.((((((..(((((......))))))))))).))))))).))).)).))))).)))))

Structure
     u     c  U   C       A      UC     ga 
ucuca gcagu aU CUC AAAAGGG GCACUU  uguuu  a
||||| ||||| || ||| ||||||| ||||||  |||||   
agagu uguca UG GAG UUUUCCU CGUGAA  acaaa  a
     u     U  U   A       C      --     ag 


Annotation confidence Not enough data
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Comments
The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2]. The 5' end of the miRNA may be offset with respect to previous annotations.

Genome context
chr19: 53679940-53680023 [+]
Clustered miRNAs
8 other miRNAs are < 10 kb from hsa-mir-519e
Name Accession Chromosome Start End Strand Confidence




Disease association
hsa-mir-519e is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature hsa-miR-519e-5p

Accession MIMAT0002828
Description Homo sapiens hsa-miR-519e-5p mature miRNA
Sequence 14 - UUCUCCAAAAGGGAGCACUUUC - 35
Evidence experimental
array-cloned [1]

Mature hsa-miR-519e-3p

Accession MIMAT0002829
Description Homo sapiens hsa-miR-519e-3p mature miRNA
Sequence 52 - AAGUGCCUCCUUUUAGAGUGUU - 73
Evidence experimental
array-cloned [1], cloned [2]

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 15965474
    Identification of hundreds of conserved and nonconserved human microRNAs
    "Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z"
    "Nat Genet (2005) 37:766-770