Stem-loop sequence hsa-mir-519a-2

Accession

MI0003182 (change log)

Symbol

HGNC:MIR519A2

Description

Homo sapiens miR-519a-2 stem-loop

Gene family

MIPF0000020; mir-515

Literature search

34 open access papers mention hsa-mir-519a-2
(224 sentences)

Stem-loop

           u   u c     c     a         guug  u 
5' ucucaggc gug c cucua aggga gcgcuuucu    uc g
   |||||||| ||| | ||||| ||||| |||||||||    || a
3' agaguuug cau g gagau uuccu cgugaaagg    ag a
           u   u u     u     a         --aa  a 

Deep sequencing

4705 reads, 8.82 reads per million, 68 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr19: 53762344-53762430 [+]
• Overlapping transcripts:

  sense

  OTTHUMT00000464285 ; VN1R2-001; 3'UTR (exon 1)

  ENST00000341702 ; VN1R2-001; 3'UTR (exon 1)

Clustered miRNAs

< 10kb from hsa-mir-519a-2

• hsa-mir-519a-1: chr19: 53752397-53752481 [+]
• hsa-mir-527: chr19: 53754018-53754102 [+]
• hsa-mir-516a-1: chr19: 53756741-53756830 [+]
• hsa-mir-1283-2: chr19: 53758232-53758318 [+]
• hsa-mir-516a-2: chr19: 53761133-53761222 [+]
• hsa-mir-519a-2: chr19: 53762344-53762430 [+]

Database links

• EntrezGene:MIR519A2
• HGNC:MIR519A2
• RNAcentral:URS0000007095_9606
• miRBase Tracker:MI0003182

Mature sequence hsa-miR-519a-2-5p

• Accession: MIMAT0037327
• Sequence: 15 - ccucuacagggaagcgcuuuc - 35
• Deep sequencing: 564 reads, 30 experiments
• Evidence: experimental; Illumina [3]

Mature sequence hsa-miR-519a-3p

• Accession: MIMAT0002869
• Previous IDs: hsa-miR-519a
• Sequence: 54 - aaagugcauccuuuuagagugu - 75
• Deep sequencing: 8268 reads, 54 experiments
• Evidence: experimental; array-cloned [1], cloned [2]
• Database links:
  • RNAcentral:URS0000135E29_9606
• Predicted targets:
  • TargetMiner:hsa-miR-519a-3p
  • TargetScanVert:hsa-miR-519a-3p
  • miRDB:hsa-miR-519a-3p
  • microrna.org:hsa-miR-519a-3p

References

1. PMID:15965474 "Identification of hundreds of conserved and nonconserved human microRNAs" Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z Nat Genet. 37:766-770(2005).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3. PMID:25822230 "Selective microRNA-Offset RNA expression in human embryonic stem cells" Asikainen S, Heikkinen L, Juhila J, Holm F, Weltner J, Trokovic R, Mikkola M, Toivonen S, Balboa D, Lampela R, Icay K, Tuuri T, Otonkoski T, Wong G, Hovatta O PLoS One. 10:e0116668(2015).