miRBase entry: hsa-mir-513a-2

Stem-loop hsa-mir-513a-2


Accession
MI0003192
Symbol
HGNC: MIR513A2
Description
Homo sapiens hsa-mir-513a-2 precursor miRNA
Gene family
MIPF0000130; mir-506

Literature search
46 open access papers mention hsa-mir-513a-2
(297 sentences)

Sequence

2880 reads, 185 reads per million, 40 experiments
ggaugccacauucagccauucagugugcagugccuUUCACAGGGAGGUGUCAUuuaugugaacuaaaauaUAAAUUUCACCUUUCUGAGAAGGguaauguacagcaugcacugcauauguggugucc
(((((((((((.(((.(((....((((((.((((((((.((((((((((..((((((((........))))))))..)))))))))).)))))))).))))))..)))..)))...)))))))))))

Structure
           --u   -c   ucag      g        A          UC        gaa 
ggaugccacau   cag  cau    ugugca ugccuUUC CAGGGAGGUG  AUuuaugu   c
|||||||||||   |||  |||    |||||| |||||||| ||||||||||  ||||||||    
ccuguggugua   guc  gua    acaugu augGGAAG GUCUUUCCAC  UAAAUaua   u
           uac   ac   --cg      a        A          UU        aaa 


Annotation confidence High
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Comments
The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context
chrX: 147225826-147225952 [-]
Clustered miRNAs
2 other miRNAs are < 10 kb from hsa-mir-513a-2
Name Accession Chromosome Start End Strand Confidence




Disease association
hsa-mir-513a-2 is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature hsa-miR-513a-5p

Accession MIMAT0002877
Description Homo sapiens hsa-miR-513a-5p mature miRNA
Sequence 36 - UUCACAGGGAGGUGUCAU - 53
Evidence experimental
array-cloned [1], cloned [2]
Database links
Predicted targets

Mature hsa-miR-513a-3p

Accession MIMAT0004777
Description Homo sapiens hsa-miR-513a-3p mature miRNA
Sequence 71 - UAAAUUUCACCUUUCUGAGAAGG - 93
Evidence experimental
cloned [2]
Database links
Predicted targets

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 15965474
    Identification of hundreds of conserved and nonconserved human microRNAs
    "Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z"
    "Nat Genet (2005) 37:766-770