miRBase entry: hsa-mir-514a-1

Stem-loop hsa-mir-514a-1


Accession
MI0003198
Symbol
HGNC: MIR514A1
Description
Homo sapiens hsa-mir-514a-1 precursor miRNA
Gene family
MIPF0000130; mir-506

Literature search
9 open access papers mention hsa-mir-514a-1
(61 sentences)

Sequence

189526 reads, 2488 reads per million, 54 experiments
aacauguugucugugguacccUACUCUGGAGAGUGACAAUCAUGuauaauuaaauuugAUUGACACUUCUGUGAGUAGAguaacgcaugacacguacg
...((((.(((((((.(((.((((((((((.((((.((((((.((........)).)))))).)))))))).)))))).))).)))).)))))))...

Structure
aac    u   -    g   c      -    G    A      U  aua 
   augu guc ugug uac cUACUC UGGA AGUG CAAUCA Gu   a
   |||| ||| |||| ||| |||||| |||| |||| |||||| ||    
   ugca cag acgc aug GAUGAG GUCU UCAC GUUAgu ua   u
gca    -   u    a   A      U    -    A      u  aau 


Annotation confidence High
Do you think this miRNA is real?
Comments
The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context
chrX: 147279247-147279344 [-]
Clustered miRNAs
3 other miRNAs are < 10 kb from hsa-mir-514a-1
Name Accession Chromosome Start End Strand Confidence




Disease association
hsa-mir-514a-1 is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature hsa-miR-514a-3p

Accession MIMAT0002883
Description Homo sapiens hsa-miR-514a-3p mature miRNA
Sequence 59 - AUUGACACUUCUGUGAGUAGA - 79
Evidence experimental
array-cloned [1], cloned [2]
Database links
Predicted targets

Mature hsa-miR-514a-5p

Accession MIMAT0022702
Description Homo sapiens hsa-miR-514a-5p mature miRNA
Sequence 22 - UACUCUGGAGAGUGACAAUCAUG - 44
Evidence not_experimental
Database links
Predicted targets

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 15965474
    Identification of hundreds of conserved and nonconserved human microRNAs
    "Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z"
    "Nat Genet (2005) 37:766-770