Stem-loop hsa-mir-615

Accession

MI0003628

Symbol

HGNC: MIR615

Description

Homo sapiens hsa-mir-615 precursor miRNA mir-615

Gene
family

RF00879; mir-615

Literature search

29 open access papers mention hsa-mir-615
(246 sentences)

Sequence

8781 reads, 56 reads per million, 103 experiments

cucgggaggggcgggagGGGGGUCCCCGGUGCUCGGAUCucgagggugcuuauuguucggUCCGAGCCUGGGUCUCCCUCUUccccccaacccccc
...(((..(((.((((((((((..(((((.((((((((..((((.(.......).)))))))))))))))))...)))))))))))))..)))...

Structure

cuc   ag   c          -UC     U        Cu    g ug 
   ggg  ggg gggagGGGGG   CCCGG GCUCGGAU  cgag g  c
   |||  ||| ||||||||||   ||||| ||||||||  |||| |  u
   ccc  ccc cccUUCUCCC   GGGUC CGAGCCUg  gcuu u  u
ccc   aa   -          UCU     -        --    g ua 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

chr12: 54033950-54034045 [+]

Disease association

hsa-mir-615 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-615-5p

• Accession: MIMAT0004804
• Description: Homo sapiens hsa-miR-615-5p mature miRNA
• Sequence: 18 - GGGGGUCCCCGGUGCUCGGAUC - 39
• Evidence: experimental ; cloned [2]

Mature hsa-miR-615-3p

• Accession: MIMAT0003283
• Description: Homo sapiens hsa-miR-615-3p mature miRNA
• Sequence: 61 - UCCGAGCCUGGGUCUCCCUCUU - 82
• Evidence: experimental ; RT-PCR [1], SAGE [1], cloned [2]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 16505370
   The colorectal microRNAome
   "Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA Jr, Sjoblom T, Barad O, Bentwich Z, Szafranska AE, Labourier E, Raymond CK, Roberts BS, Juhl H, Kinzler KW, Vogelstein B, Velculescu VE"
   "Proc Natl Acad Sci U S A (2006) 103:3687-3692