miRBase entry: hsa-mir-548c

Stem-loop hsa-mir-548c


Accession
MI0003630
Symbol
HGNC: MIR548C
Description
Homo sapiens hsa-mir-548c precursor miRNA
Gene family
MIPF0000317; mir-548

Literature search
58 open access papers mention hsa-mir-548c
(257 sentences)

Sequence

2341 reads, 142 reads per million, 85 experiments
cauuggcaucuauuagguuggugcAAAAGUAAUUGCGGUUUUUGCCauuacuuucaguagCAAAAAUCUCAAUUACUUUUGCaccaacuuaauacuu
..........(((((((((((((((((((((((((.(((((((((...((((...))))))))))))).)))))))))))))))))))))))))...

Structure
cauuggcauc                         C         Cau    u 
          uauuagguuggugcAAAAGUAAUUG GGUUUUUGC   uacu  
          ||||||||||||||||||||||||| |||||||||   |||| u
          auaauucaaccaCGUUUUCAUUAAC CUAAAAACg   auga  
-------uuc                         U         ---    c 


Annotation confidence Not enough data
Do you think this miRNA is real?
Comments
Extensive cloning studies suggest that the 5' miRNA may be the predominant one [2].

Genome context
chr12: 64622509-64622605 [+]
Clustered miRNAs
1 other miRNA is < 10 kb from hsa-mir-548c
Name Accession Chromosome Start End Strand Confidence




Disease association
hsa-mir-548c is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature hsa-miR-548c-5p

Accession MIMAT0004806
Description Homo sapiens hsa-miR-548c-5p mature miRNA
Sequence 25 - AAAAGUAAUUGCGGUUUUUGCC - 46
Evidence experimental
cloned [2]
Database links
Predicted targets

Mature hsa-miR-548c-3p

Accession MIMAT0003285
Description Homo sapiens hsa-miR-548c-3p mature miRNA
Sequence 61 - CAAAAAUCUCAAUUACUUUUGC - 82
Evidence experimental
SAGE [1]

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 16505370
    The colorectal microRNAome
    "Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA Jr, Sjoblom T, Barad O, Bentwich Z, Szafranska AE, Labourier E, Raymond CK, Roberts BS, Juhl H, Kinzler KW, Vogelstein B, Velculescu VE"
    "Proc Natl Acad Sci U S A (2006) 103:3687-3692