Accession
MI0003672
Symbol
HGNC:
MIR663A
Description
Homo sapiens
hsa-mir-663a precursor miRNA
Gene family
MIPF0000462;
mir-663
Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?
MIR663A is a microRNA that has been found to suppress colorectal cancer (CC) metastasis [PMC6365692]. In contrast, TTC22V1 has been shown to promote CC metastasis [PMC6365692]. The significance of MIR663A downregulation by MALAT1 was evaluated by studying the expression changes of a set of MIR663A target genes, including P5319, PIK3CD12, P2111, CXCR413, TGFB120, and JUND21, in HCT116 cells [PMC6113222].
Literature search
75 open access papers mention hsa-mir-663a
(535 sentences)
(535 sentences)
Sequence
1048
reads,
493
reads per million, 76 experiments
ccuuccggcgucccAGGCGGGGCGCCGCGGGACCGCccucgugucuguggcggugggaucccgcggccguguuuuccugguggcccggccaug
....((((.((((((((.((.(((((((((((((((((........).))))).....)))))))).))).))..))))).))))))).....
....((((.((((((((.((.(((((((((((((((((........).))))).....)))))))).))).))..))))).))))))).....
Structure
-ccuu c - -C G - ----- - ucg
ccgg guc ccAGG GG GCG CCGCGGGA CCGCc c u
|||| ||| ||||| || ||| |||||||| ||||| |
ggcc cgg ggucc uu ugc ggcgcccu ggcgg g g
guacc - u uu g c agggu u ucu
Annotation confidence
Low
Do you think this miRNA is real?
Genome context
chr20: 26208186-26208278 [-]
Disease association
hsa-mir-663a is associated with one or more human diseases in the Human microRNA Disease Database
| Disease | Description | Category | PubMed ID |
|---|
Database links
Mature hsa-miR-663a
| Accession | MIMAT0003326 |
| Description | Homo sapiens hsa-miR-663a mature miRNA |
| Sequence | 15 - AGGCGGGGCGCCGCGGGACCGC - 36 |
| Evidence |
experimental
SAGE [1] |
| Database links |
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| Predicted targets |
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References
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