miRBase entry: hsa-mir-744

Stem-loop hsa-mir-744


Accession
MI0005559
Symbol
HGNC: MIR744
Description
Homo sapiens hsa-mir-744 precursor miRNA
Gene family
MIPF0000431; mir-744

Literature search
47 open access papers mention hsa-mir-744
(449 sentences)

Sequence

159015 reads, 697 reads per million, 134 experiments
uugggcaaggUGCGGGGCUAGGGCUAACAGCAgucuuacugaagguuuccuggaaaccacgcacaugCUGUUGCCACUAACCUCAACCUuacucgguc
(((((.(((((..((((.((((((.(((((((...........((((((...)))))).......)))))))))).))).)))).))))).)))))..

Structure
--     c     GC    C   -   U       gucuuacugaa      c 
  uuggg aaggU  GGGG UAG GGC AACAGCA           gguuuc  
  ||||| |||||  |||| ||| ||| |||||||           |||||| u
  ggcuc uUCCA  CUCC AUC CCG UUGUCgu           ccaaag  
cu     a     -A    A   A   -       ----acacgca      g 


Annotation confidence High
Do you think this miRNA is real?
Comments
This sequence was identified as a miRNA candidate by Berezikov et al. using RAKE and MPSS techniques [1]. Expression was later confirmed by cloning [2].

Genome context
chr17: 12081899-12081996 [+]

Disease association
hsa-mir-744 is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature hsa-miR-744-5p

Accession MIMAT0004945
Description Homo sapiens hsa-miR-744-5p mature miRNA
Sequence 11 - UGCGGGGCUAGGGCUAACAGCA - 32
Evidence experimental
cloned [2]
Database links
Predicted targets

Mature hsa-miR-744-3p

Accession MIMAT0004946
Description Homo sapiens hsa-miR-744-3p mature miRNA
Sequence 68 - CUGUUGCCACUAACCUCAACCU - 89
Evidence experimental
cloned [2]
Database links
Predicted targets

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 16954537
    Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis
    "Berezikov E, van Tetering G, Verheul M, van de Belt J, van Laake L, Vos J, Verloop R, van de Wetering M, Guryev V, Takada S, van Zonneveld AJ, Mano H, Plasterk R, Cuppen E"
    "Genome Res (2006) 16:1289-1298