Stem-loop sequence hsa-mir-744

Accession

MI0005559 (change log)

Symbol

HGNC:MIR744

Description

Homo sapiens miR-744 stem-loop

Gene family

MIPF0000431; mir-744

Literature search

47 open access papers mention hsa-mir-744
(444 sentences)

Stem-loop

   --     c     gc    c   -   u       gucuuacugaagguu 
5'   uuggg aaggu  gggg uag ggc aacagca               u
     ||||| |||||  |||| ||| ||| |||||||               c
3'   ggcuc uucca  cucc auc ccg uugucgu               c
   cu     a     -a    a   a   -       acacgcaccaaaggu 

Deep sequencing

196641 reads, 325 reads per million, 158 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Comments

This sequence was identified as a miRNA candidate by Berezikov et al. using RAKE and MPSS techniques [1]. Expression was later confirmed by cloning [2].

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr17: 12081899-12081996 [+]
• Overlapping transcripts:

  intergenic

Database links

• EntrezGene:MIR744
• HGNC:MIR744
• RNAcentral:URS00000EC1BE_9606
• miRBase Tracker:MI0005559

Mature sequence hsa-miR-744-5p

• Accession: MIMAT0004945
• Previous IDs: hsa-miR-744
• Sequence: 11 - ugcggggcuagggcuaacagca - 32
• Deep sequencing: 194434 reads, 157 experiments
• Evidence: experimental; cloned [2]
• Database links:
  • RNAcentral:URS00002ED61F_9606
• Predicted targets:
  • TargetMiner:hsa-miR-744-5p
  • TargetScanVert:hsa-miR-744-5p
  • miRDB:hsa-miR-744-5p
  • microrna.org:hsa-miR-744-5p

Mature sequence hsa-miR-744-3p

• Accession: MIMAT0004946
• Previous IDs: hsa-miR-744*
• Sequence: 68 - cuguugccacuaaccucaaccu - 89
• Deep sequencing: 2201 reads, 137 experiments
• Evidence: experimental; cloned [2]
• Database links:
  • RNAcentral:URS00005FAA14_9606
• Predicted targets:
  • TargetMiner:hsa-miR-744-3p
  • TargetScanVert:hsa-miR-744-3p
  • miRDB:hsa-miR-744-3p
  • microrna.org:hsa-miR-744-3p

References

1. PMID:16954537 "Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis" Berezikov E, van Tetering G, Verheul M, van de Belt J, van Laake L, Vos J, Verloop R, van de Wetering M, Guryev V, Takada S, van Zonneveld AJ, Mano H, Plasterk R, Cuppen E Genome Res. 16:1289-1298(2006).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).