miRBase entry: ppt-MIR414

Stem-loop ppt-MIR414


Accession
MI0005669
Description
Physcomitrella patens ppt-MIR414 precursor miRNA
Gene family
MIPF0000375; MIR414

Literature search
1 open access papers mention ppt-MIR414
(2 sentences)

Sequence

agacguucaagaacaauuagagaagaccaaugcuagaauguggggcucaccagauuuuccaacugcauuggcuagcucugcuagcgcuuuggcaguaaccauaucuuugucaucuucaucaucgucaucuucgucaucaucuucgUCAUCCUCAUCAUCCUCGUCCucagcaucag
.((((...((((.......((((.(((((((((.(((((.(((......))).)))))......))))))((((((...))))))....((((((...........))))))...........))).))))........)))))))).............................

Structure
----------------------------a    uuc    -acaauua    a   -----------------------------------------------------      -----u     g   gg 
                             gacg   aaga        gaga gac                                                     caaugc      agaau ugg  c
                             ||||   ||||        |||| |||                                                     ||||||      ||||| |||   
                             CUgc   uucu        uucu cug                                                     guuacg      uuuua acc  u
gacuacgacuCCUGCUCCUACUACUCCUA    ---    acuacugc    a   cuacuacuucuacuguuucuauaccaaugacgguuucgcgaucgucucgaucg      ucaacc     g   ac 


Annotation confidence Not enough data
Do you think this miRNA is real?
Comments
The status of this sequence as a miRNA has been questioned on the basis of lack of conservation in genomes other than Arabidopsis and rice, moderately poor precursor hairpin structure, lack of identified targets, and low Northern blot signal [2]. This sequence may therefore be removed in subsequent data releases.

Genome context
Chr11: 12877706-12877881 [+]

Database links

Mature ppt-miR414

Accession MIMAT0004357
Description Physcomitrella patens ppt-miR414 mature miRNA
Sequence 146 - UCAUCCUCAUCAUCCUCGUCC - 166
Evidence experimental
Northern [1]

References

  1. PubMed ID: 16669754
    MicroRNAS and their regulatory roles in plants
    "Jones-Rhoades MW, Bartel DP, Bartel B"
    "Annu Rev Plant Biol (2006) 57:19-53

  2. PubMed ID: 17359535
    Evidence for the rapid expansion of microRNA-mediated regulation in early land plant evolution
    Fattash I, Voss B, Reski R, Hess WR, Frank W
    BMC Plant Biol (2007) 7:13