miRBase entry: ame-mir-190

Stem-loop ame-mir-190


Accession
MI0005750
Description
Apis mellifera ame-mir-190 precursor miRNA
Gene family
MIPF0000076; mir-190

Literature search
2 open access papers mention ame-mir-190
(4 sentences)

Sequence

caaacaagucgucugguuuccguaAGAUAUGUUUGAUAUUCUUGGUUGUUuuuuaaagaaucgaccaggaaucaaacauauuauuaugguggucagaaaa
...........(((((((.((((((((((((((((((..(((((((((.((((...)))).))))))))))))))))))))).)))))).)))))))...

Structure
caaacaagucg       u      -            AU         U    u 
           ucugguu ccguaA GAUAUGUUUGAU  UCUUGGUUG Uuuu  
           ||||||| |||||| ||||||||||||  ||||||||| |||| a
           agacugg gguauu uuauacaaacua  aggaccagc aaga  
--------aaa       u      a            --         u    a 


Annotation confidence Not enough data
Do you think this miRNA is real?
Comments
Weaver et al. identify this bee homolog of human mir-190b [1]. They also report a second predicted hairpin on the opposite strand, with RT-PCR evidence for the expression of a second mature miRNA (UAAUAAUAUGUUUGAUUCCUGG).

Genome context
CM000064.5: 9278012-9278111 [+]

Database links

Mature ame-miR-190-5p

Accession MIMAT0004440
Description Apis mellifera ame-miR-190-5p mature miRNA
Sequence 25 - AGAUAUGUUUGAUAUUCUUGGUUGUU - 50
Evidence experimental
RTPCR [1], Illumina [2]

References

  1. PubMed ID: 17543122
    Computational and transcriptional evidence for microRNAs in the honey bee genome
    Weaver DB, Anzola JM, Evans JD, Reid JG, Reese JT, Childs KL, Zdobnov EM, Samanta MP, Miller J, Elsik CG
    Genome Biol (2007) 8:R97

  2. PubMed ID: 22409512
    Behavioral plasticity in honey bees is associated with differences in brain microRNA transcriptome
    "Greenberg JK, Xia J, Zhou X, Thatcher SR, Gu X, Ament SA, Newman TC, Green PJ, Zhang W, Robinson GE, Ben-Shahar Y"
    "Genes Brain Behav (2012) 11:660-670