miRBase entry: mcmv-mir-m108-2

Stem-loop mcmv-mir-m108-2


Accession
MI0006263
Description
Mouse cytomegalovirus mcmv-mir-m108-2 precursor miRNA
Gene family
MIPF0000446; mir-m107-1


Sequence

gaUCACUCGUCGCGAGCGGUCACUCGACGCGAGCACCGagucgcuacggacgGUGACUCGAGACGAGUGACCGGUcgacgagcguc
((.(.((((((..((.((((((((((.(.((((((((..(((......))))))).)))).).)))))))))).)))))))).)))

Structure
  U A      GC  G          A G    -    Ga   gc 
ga C CUCGUC  GA CGGUCACUCG C CGAG CACC  guc  u
|| | ||||||  || |||||||||| | |||| ||||  |||   
cu g gagcag  cU GCCAGUGAGC G GCUC GUGg  cag  a
  - c      --  G          A A    A    --   gc 


Annotation confidence Not enough data
Do you think this miRNA is real?
Comments
Buck et al [1] and Dolken et al [2] cloned alternative offset mature miRNA sequences from the 5' arm of this hairpin precursor, named mir-m108-2-5p.1 and .2 here.

Genome context
Unknown

Database links

Mature mcmv-miR-m108-2-5p.2

Accession MIMAT0005559
Description Mouse cytomegalovirus mcmv-miR-m108-2-5p.2 mature miRNA
Sequence 3 - UCACUCGUCGCGAGCGGUCAC - 23
Evidence experimental
cloned [1]

Mature mcmv-miR-m108-2-5p.1

Accession MIMAT0005560
Description Mouse cytomegalovirus mcmv-miR-m108-2-5p.1 mature miRNA
Sequence 16 - GCGGUCACUCGACGCGAGCACCG - 38
Evidence experimental
cloned [2]

Mature mcmv-miR-m108-2-3p

Accession MIMAT0005561
Description Mouse cytomegalovirus mcmv-miR-m108-2-3p mature miRNA
Sequence 53 - GUGACUCGAGACGAGUGACCGGU - 75
Evidence experimental
cloned [1-2]

References

  1. PubMed ID: 17942535
    Mouse cytomegalovirus microRNAs dominate the cellular small RNA profile during lytic infection and show features of posttranscriptional regulation
    "Dolken L, Perot J, Cognat V, Alioua A, John M, Soutschek J, Ruzsics Z, Koszinowski U, Voinnet O, Pfeffer S"
    "J Virol (2007) 81:13771-13782

  2. PubMed ID: 17928340
    Discrete clusters of virus-encoded micrornas are associated with complementary strands of the genome and the 7.2-kilobase stable intron in murine cytomegalovirus
    "Buck AH, Santoyo-Lopez J, Robertson KA, Kumar DS, Reczko M, Ghazal P"
    "J Virol (2007) 81:13761-13770