Stem-loop sequence mmu-mir-1983

Accession

MI0009990 (change log)

Symbol

MGI:Mir1983

Description

Mus musculus miR-1983 stem-loop

Literature search

8 open access papers mention mmu-mir-1983
(13 sentences)

Stem-loop

   ---ccuuuaca                 ---u   --------    --     uag   g g    u     a 
5'            gagaaagcaugcuccag    ggc        gcaa  ucggu   cgc c guac uauac g
              |||||||||||||||||    |||        ||||  |||||   ||| | |||| |||||  
3'            uucuuuuguacgagguc    ccg        uguu  agccg   gug g cgug auaug c
   ccgccuuuccc                 cacu   agcuugag    gg     -ua   - g    u     a 

Deep sequencing

33124 reads, 64.5 reads per million, 107 experiments

Confidence

Annotation confidence: not enough data

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Comments

Babiarz et al. show that mir-1983 is derived from Dicer-dependent processing of an alternative hairpin conformation of a tRNA(Ile) sequence [1]. The biological significance of the mature miRNA is unknown, and tRNA-derived miRNA sequences are not expected to be prevalent.

Genome context

• Coordinates (GRCm38; GCA_000001635.2): chr13: 21896918-21897049 [-]
• Overlapping transcripts:

  intergenic

Database links

• EntrezGene:Mir1983
• MGI:Mir1983
• RNAcentral:URS000075BF24_10090
• miRBase Tracker:MI0009990

Mature sequence mmu-miR-1983

• Accession: MIMAT0009455
• Sequence: 100 - cucaccuggagcauguuuucu - 120
• Deep sequencing: 24216 reads, 101 experiments
• Evidence: experimental; Illumina [1]
• Database links:
  • RNAcentral:URS000050CF2F_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-1983
  • miRDB:mmu-miR-1983
  • microrna.org:mmu-miR-1983

References

1. PMID:18923076 "Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs" Babiarz JE, Ruby JG, Wang Y, Bartel DP, Blelloch R Genes Dev. 22:2773-2785(2008).