miRBase entry: bta-mir-2904-1

Stem-loop bta-mir-2904-1


Accession
MI0013080
Description
Bos taurus bta-mir-2904-1 precursor miRNA
Gene family
MIPF0000872; mir-2904

Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?

Bta-mir-2904 is a miRNA that has been identified as one of the top differentially expressed miRNAs [PMC9810022]. It has been associated with a bacterial cluster comprising Prevotella, Bacteroides, Ruminococcus, Propionibacterium, and Klebsiella [PMC6708143]. Bta-mir-2904 exhibits the highest diversity of isomiRs, with numerous variants at both the 5' and 3' ends [PMC4609085]. It has also been found to be highly expressed in certain groups compared to control groups, such as in the SA group [PMC6896338] and LF bulls [PMC8329915]. Bta-mir-2904 has been shown to target genes such as IL1A and DEXH Asp-Glu-X-His box polypeptide 58 (DHX58) [PMC7943879]. In different studies, bta-mir-2904 has shown both upregulation and downregulation in expression levels compared to control groups or other conditions [PMC7943879] [PMC8903571] [PMC5414302] [PMC7519046]. Additionally, bta-mir-2904 is one of the miRNAs significantly enriched in HS-EVs compared to control-EVs [PMC7519046]. Overall, bta-mir-2904 exhibits differential expression patterns and potential target genes that may be associated with various biological processes.

Literature search
4 open access papers mention bta-mir-2904-1
(6 sentences)

Sequence

11057 reads, 1158 reads per million, 73 experiments
acggcagcgccgcGGGAGCCUCGGUUGGCCUCggauagccggucccccgccguccccgccggcgggccgu
(((((..(((((((((.((..(((..((((..((....))))))..)))..)).)))).))))).)))))

Structure
     ag     -    A  CU   UU    UC  a 
acggc  cgccg cGGG GC  CGG  GGCC  gg u
|||||  ||||| |||| ||  |||  ||||  ||  
ugccg  gcggc gccc ug  gcc  cugg  cc a
     -g     c    c  cc   cc    --  g 


Annotation confidence Low
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Genome context
chr2: 66499624-66499693 [+]
Clustered miRNAs
1 other miRNA is < 10 kb from bta-mir-2904-1
Name Accession Chromosome Start End Strand Confidence




Database links

Mature bta-miR-2904

Accession MIMAT0013862
Description Bos taurus bta-miR-2904 mature miRNA
Sequence 14 - GGGAGCCUCGGUUGGCCUC - 32
Evidence experimental
cloned [1]

References

  1. PubMed ID: 19765282
    Identification and characterization of miRNAs expressed in the bovine ovary
    Hossain MM, Ghanem N, Hoelker M, Rings F, Phatsara C, Tholen E, Schellander K, Tesfaye D
    BMC Genomics (2009) 10:443