miRBase entry: hsa-mir-323b

Stem-loop hsa-mir-323b


Accession
MI0014206
Symbol
HGNC: MIR323B
Description
Homo sapiens hsa-mir-323b precursor miRNA
Gene family
MIPF0000018; mir-154

Literature search
47 open access papers mention hsa-mir-323b
(109 sentences)

Sequence

277 reads, 21 reads per million, 29 experiments
ugguacucggagggAGGUUGUCCGUGGUGAGUUCGCAuuauuuaaugaugCCCAAUACACGGUCGACCUCUUuucgguauca
((((((.(((((((((((((.(((((........(((((((...)))))))......))))).)))))))))))))))))))

Structure
      u             U     GUGAGUUC       u 
ugguac cggagggAGGUUG CCGUG        GCAuuau  
|||||| ||||||||||||| |||||        ||||||| u
acuaug gcuuUUCUCCAGC GGCAC        Cguagua  
      -             U     --AUAACC       a 


Annotation confidence High
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Comments
miR-323b-5p was previously named miR-453 here and in [1,2], but appears to be processed from the same hairpin as miR-332b-3p identified in [3]. Entries for mir-323b and mir-453 are merged here.

Genome context
chr14: 101056219-101056300 [+]
Clustered miRNAs
18 other miRNAs are < 10 kb from hsa-mir-323b
Name Accession Chromosome Start End Strand Confidence




Database links

Mature hsa-miR-323b-5p

Accession MIMAT0001630
Description Homo sapiens hsa-miR-323b-5p mature miRNA
Sequence 15 - AGGUUGUCCGUGGUGAGUUCGCA - 37
Evidence experimental
cloned [1-2]

Mature hsa-miR-323b-3p

Accession MIMAT0015050
Description Homo sapiens hsa-miR-323b-3p mature miRNA
Sequence 51 - CCCAAUACACGGUCGACCUCUU - 72
Evidence experimental
Illumina [3]
Database links
Predicted targets

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 15891114
    Clustering and conservation patterns of human microRNAs
    "Altuvia Y, Landgraf P, Lithwick G, Elefant N, Pfeffer S, Aravin A, Brownstein MJ, Tuschl T, Margalit H"
    "Nucleic Acids Res (2005) 33:2697-2706

  3. PubMed ID: 20300190
    Characterization of the Melanoma miRNAome by Deep Sequencing
    "Stark MS, Tyagi S, Nancarrow DJ, Boyle GM, Cook AL, Whiteman DC, Parsons PG, Schmidt C, Sturm RA, Hayward NK"
    "PLoS One (2010) 5:e9685