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12 publications mentioning dme-mir-13a

Open access articles that are associated with the species Drosophila melanogaster and mention the gene name mir-13a. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 14
mir-2 and mir-13 repress translation of the target genes, grim, skl and rpr, suggesting that they may be involved in regulating apoptosis [48]. [score:6]
bmo-miR-2b, which is found in the gene cluster bmo-miR-2a-1/bmo-miR-2a-1*/bmo-miR-2a-2/bmo-miR-2b/bmo-miR-13a*/bmo-miR-13b, encodes a newly identified member of the mir-2 family. [score:1]
We designated these sequences bmo-miR-13a*, bmo-miR-14, bmo-miR-46, bmo-miR-46*, bmo-miR-71, bmo-miR-277 and bmo-bantam. [score:1]
Searching the D. melanogaster and A. gambiae miRNAs, we found that corresponding mir-2 and mir-13 family members also assembled into clusters in these two species. [score:1]
These newly identified miRNAs are bmo-miR-2a*, bmo-miR-8*, bmo-miR-13a*, bmo-miR-46*, bmo-miR-263*, bmo-miR-279*, and bmo-miR-305*. [score:1]
Examining the positions of the identified miRNAs in the B. mori genome, we identified two miRNA clusters (Figure 4): bmo-miR-2a-1/bmo-miR-2a-1*/bmo-miR-2a-2/bmo-miR-2b/bmo-miR-13a*/bmo-miR-13b; and bmo-miR-275/bmo-miR-305/bmo-miR-305*. [score:1]
Genes in the cluster containing bmo-miR-2a-1/bmo-miR-2a-1*/bmo-miR-2a-2/bmo-miR-2b/bmo-miR-13a*/bmo-miR-13b are members of the mir-2 miRNA family. [score:1]
4220] of these six genes can bind perfectly to mir-2 (bmo-miR-2a, bmo-miR-2b, bmo-miR-13a* and bmo-miR-13b) and bmo-miR-7, respectively. [score:1]
a. bmo-miR-2a-1/bmo-miR-2a-1*/bmo-miR-2a-2/bmo-miR-2b/bmo-miR-13a*/bmo-miR-13b; b. bmo-miR-275/bmo-miR-305/bmo-miR-305*. [score:1]
[1 to 20 of 9 sentences]
[+] score: 10
Therefore, feeding of the DCPTN-PT containing culture media did not depress the regulatory microRNAs (miR-2, miR-13 and miR-14) that control the translation of three pro-apoptotic host genes (miR-2 and miR-13 targets rpr, grim and miR-14 targets Drice), suggesting that DCPTN-PT compound is not an inhibitor of all proapoptotic genes but very specific to oncomiR bantam. [score:10]
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[+] score: 4
These included miR-SPs targeting bantam, miR-1, the K-box family (miR-2b, miR-2c and miR-13b displayed strong phenotypes; miR-2a and miR-13a were flight impaired but fell below our stringent cutoff; ), miR-7, the miR-31 family, miR-34, miR-190, miR-957, miR-986, miR-987 and miR-1001. [score:3]
Supporting this argument, several hits in the viability screen belonged to the K-box family (miR-2a, miR-2b and miR-2c, and miR-13a and miR-13b) and the miR-9 family (miR-9b and miR-9c). [score:1]
[1 to 20 of 2 sentences]
[+] score: 3
Depletion of yki in S2 cells by RNAi led to a significant reduction in the levels of expression of miR-2a and b (P<0.05, Fig.  3B; miR-13a/b were on average lower, but the effect was variable and so not statistically significant). [score:3]
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[+] score: 3
In the 13b~2c cluster a wrong conclusion of a lack of correlation of dme-mir-13b-1 to dme-mir-13a and dme-mir-2c can be formally deduced due to the superposition of the expression of the non-clustered paralog dme-mir-13b-2 with identical sequence. [score:3]
[1 to 20 of 1 sentences]
[+] score: 3
Interestingly, we have earlier shown that a cluster of three K box miRNAs (mir-2c, mir-13a and mir-13b-1) is specifically expressed throughout the embryonic CNS [8], and other Hox miRNAs (e. g. mir-iab-4 and mir-iab-8) are restricted to specific anterior-posterior domains in the CNS of germband-retracted embryos [51]. [score:3]
[1 to 20 of 1 sentences]
[+] score: 3
The SLS output contained five predictions with significant similarity to the HOM output (ame-mir-13a, ame-mir-276, ame-mir-305, ame-mir-92 and ame-mir-9a) and only two predictions with significant similarity to the top 25 MCE candidates, both of which were variants of C5152. [score:1]
In D. melanogaster, the proapoptotic K-box miRNA mir-2, and mir-13 occur jointly. [score:1]
Finally, three copies of ame-mir-2, plus one instance each of ame-mir-13a and ame-mir-71, all occur within intron 3 of GB15727 - a serine/threonine phosphatase lost from Drosophila, but with both vertebrate and more ancient metazoan orthologs. [score:1]
[1 to 20 of 3 sentences]
[+] score: 3
However, there are numerous examples of microRNAs that are present in RISC more than expected from their expression levels (miR-14-3p, miR-317-3p, 275-3p) or less than expected (miR-13a-3p, miR-317-5p, miR-190-3p). [score:3]
[1 to 20 of 1 sentences]
[+] score: 2
A cluster of miR-2a-1, miR-2a-2, miR-2b, miR-13a and miR-13b is localized on chromosome 1 of B. mori, indicating there are two precursors of miR-2a, and miR-2a-2 is in the interior of this cluster. [score:1]
By searching bmo-miR-2a in Silkworm Genome Database, it is noticed that there are two precursors of pre-bmo-miR-2a which localized on chromosome 1 and organized as a cluster with pre-miR-2b, pre-miR-13a and pre-miR-13b (Figure 5). [score:1]
[1 to 20 of 2 sentences]
[+] score: 2
Two of the five clusters, mir-13b-1/mir-13a/mir-2c and mir-2a-2/mir-2a-1/mir-2b-2, are derived from a single ancestral mir-2/mir-13 cluster (48, 49). [score:1]
All members of the mir-2/mir-13 ancestral cluster belong to the same family (the mir-2 family), suggesting that the ancestral cluster originated by tandem duplication. [score:1]
[1 to 20 of 2 sentences]
[+] score: 1
The cluster (sfr-mir-2a, sfr-mir-2b, sfr-mir-2c, sfr-mir-13a, sfr-mir-13b) is distributed over the region, 8161–8774 of scaffold 1973 with a size of 20411bp (Fig. 3B, i), while the other (sfr-mir-10494, sfr-mir-10463, sfr-mir-10471) span over 10636bp region of scaffold 6745. [score:1]
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[+] score: 1
For sickle we found one conserved site in all flies for miR-2, miR-13, and miR-6, which share the same nucleus. [score:1]
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