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19 publications mentioning gga-mir-148a

Open access articles that are associated with the species Gallus gallus and mention the gene name mir-148a. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 17
These miRNAs were divided into three groups according to their expression levels in the fat broiler line, 4 highly expressed (gga-miR-21, gga-miR-148a, gga-miR-103, gga-miR-101) (2 [-ΔCt] >0.7), 4 moderately expressed (gga-miR-100, gga-miR-146a, gga-miR-92, gga-miR-2188) (0.7>2 [-ΔCt]>0.08), and 7 lowly expressed (gga-miR-1a, gga-miR-130a, gga-miR-221, gga-miR-19a, gga-miR-181b, gga-miR-458, gga-miR-17–3p) (2 [-ΔCt]<0.08) (Table 2). [score:9]
Seven miRNAs (gga-miR-148a, gga-miR-101, gga-miR-100, gga-miR-92, gga-miR-130a, gga-miR-19a and gga-miR-221) with significantly differential expression levels were found (* P<0.05; ** P<0.01). [score:3]
Recently, miR-148a was found to be able to target DNMT1, affecting the methylation status of adipocytes [49]. [score:3]
Three other miRNAs, gga-miR-148a, gga-miR-146c and gga-miR-10a were more abundant in the lean line than in the fat line. [score:1]
The top 10 abundant miRNAs included the let-7 miRNA family (let-7a, j, b, f, c, and k), gga-miR-148a, gga-miR-146c, gga-miR-10a, and gga-miR-21. [score:1]
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2
[+] score: 9
For example, miR-126, -30d and -10a are relevant to porcine muscle development 33, and miR-148a mediates myogenic differentiation through targeting ROCK1 34. [score:4]
MiR-22-3p (−1.33-fold) exhibited the highest expression levels in both libraries, followed by miR-148a-3p (−1.35-fold), whereas miR-146c-5p (−3.69-fold) exhibited the maximum fold-change. [score:3]
A previous study demonstrated that miR-148a, miR-122, and miR-21-5p were the most abundant miRNAs in porcine liver 32. [score:1]
In addition, some other miRNAs, such as miR-148a, miR-122, miR-21-5p, Let-7f-5p, miR-26a-5p, miR-126-5p, miR-30d, and miR-10a-5p, were also highly abundant in chicken liver. [score:1]
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3
[+] score: 8
Among the known miRNAs, miR-10b-5p, gga-miR-148a-3p, gga-miR-22-3p and gga-miR-133a-3p were relatively high expressed in all three stages of chicken skeletal muscle development. [score:4]
In this group, miR-10b-5p, miR-148a-3p and miR-133a-3p were the most abundant accounting for 79,359, 171,817 and 404,782 of total normalized miRNA reads from the E11, E16 and P1 libraries, respectively. [score:1]
The 20 most abundant miRNAs in the three groups were ordered by the average proportion of each miRNA and included miR-148a-3p, miR-22-3p, miR-10b-5p, miR-181a-5p, miR-133a-3p, miR-126-5p, let-7f-5p, miR-10a-5p, miR-30c-5p, miR-146c-5p (Supplementary Table 1). [score:1]
Figure 2 The muscle specific miRNAs (myo-miR), miR-133a/b, miR-206, miR-486, miR-26a, miR-27b, miR-378, miR-148a and miR-181 were highly enriched in skeletal muscle and play key roles in skeletal muscle metabolism [11]. [score:1]
Figure 2The muscle specific miRNAs (myo-miR), miR-133a/b, miR-206, miR-486, miR-26a, miR-27b, miR-378, miR-148a and miR-181 were highly enriched in skeletal muscle and play key roles in skeletal muscle metabolism [11]. [score:1]
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4
[+] score: 7
Other miRNAs from this paper: hsa-let-7d, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-17, hsa-mir-21, hsa-mir-22, hsa-mir-30a, hsa-mir-32, hsa-mir-33a, hsa-mir-148a, hsa-mir-30c-2, hsa-mir-30d, hsa-mir-147a, hsa-mir-34a, hsa-mir-187, hsa-mir-204, hsa-mir-205, hsa-mir-200b, hsa-mir-23b, hsa-mir-30b, hsa-mir-125b-1, hsa-mir-138-2, hsa-mir-142, hsa-mir-144, hsa-mir-125b-2, hsa-mir-138-1, hsa-mir-146a, hsa-mir-190a, hsa-mir-200c, hsa-mir-155, hsa-mir-30c-1, hsa-mir-200a, hsa-mir-30e, hsa-mir-365b, hsa-mir-328, gga-mir-33-1, gga-mir-125b-2, gga-mir-155, gga-mir-17, gga-mir-138-1, gga-mir-187, gga-mir-32, gga-mir-30d, gga-mir-30b, gga-mir-30a, gga-mir-30c-2, gga-mir-190a, gga-mir-204-2, gga-mir-138-2, gga-let-7d, gga-let-7f, gga-mir-146a, gga-mir-205b, gga-mir-200a, gga-mir-200b, gga-mir-34a, gga-mir-30e, gga-mir-30c-1, gga-mir-205a, gga-mir-204-1, gga-mir-23b, gga-mir-142, hsa-mir-449a, hsa-mir-489, hsa-mir-146b, hsa-mir-548a-1, hsa-mir-548a-2, hsa-mir-548a-3, hsa-mir-33b, hsa-mir-449b, gga-mir-146b, gga-mir-147, gga-mir-489, gga-mir-449a, hsa-mir-449c, gga-mir-21, gga-mir-144, gga-mir-460a, hsa-mir-147b, hsa-mir-190b, gga-mir-22, gga-mir-460b, gga-mir-1662, gga-mir-1684a, gga-mir-449c, gga-mir-146c, gga-mir-449b, gga-mir-2954, hsa-mir-548aa-1, hsa-mir-548aa-2, hsa-mir-548ab, hsa-mir-548ac, hsa-mir-548ad, hsa-mir-548ae-1, hsa-mir-548ae-2, hsa-mir-548ag-1, hsa-mir-548ag-2, hsa-mir-548ah, hsa-mir-548ai, hsa-mir-548aj-1, hsa-mir-548aj-2, hsa-mir-548ak, hsa-mir-548al, hsa-mir-548am, hsa-mir-548an, hsa-mir-548ao, hsa-mir-548ap, hsa-mir-548aq, hsa-mir-548ar, hsa-mir-548as, hsa-mir-548at, hsa-mir-548au, hsa-mir-548av, hsa-mir-548aw, hsa-mir-548ax, hsa-mir-548ay, hsa-mir-548az, gga-mir-365b, gga-mir-33-2, gga-mir-125b-1, gga-mir-190b, gga-mir-449d, gga-mir-205c
Likewise, from the miRNA-mRNA association, the under expressed genes LZTFL1, JAZF1, THBS2 and RPS14 were associated with microRNAs (miR-146b-5p, miR-1684a-3p, miR-460b-3p, miR-30e-5p, miR-33-5p, miR-148a-5p, miR-32-5p, miR-155 and miR-144-3p) that were down-regulated in pulmonary arteries (Figure 4). [score:6]
Nonetheless, miR-142-3p, miR-449-5p, miR-148a-5p, miR-365b-5p, miR-200-3p, miR-34a-5p and miR-1443-3p found in our results have few reported associations to PAH. [score:1]
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5
[+] score: 7
Other miRNAs from this paper: gga-mir-106, gga-mir-126
Emerging evidence has revealed a general necessity for miRNAs in osteoclastogenesis, knowing that ectopic expression of miR-148a and miR-503 inhibited the expression of V-maf musculoaponeurotic fibrosarcoma oncogene homolog B (MAFB) [20] and RANK [21], resulting in the blockage of osteoclast differentiation. [score:7]
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6
[+] score: 6
In the presence of miR-148a or miR-1612 for DNMT1, neither the intensity nor percentage of GFP -expressing cells changed (data now shown). [score:3]
For the dual fluorescence reporter assay, the fusion contained the DsRed gene and either miR-148a or miR-1612 for DNMT1; miR-1596, miR-1687, miR-1741, or miR-1749 for DNMT3A; and miR-16c, miR-222, or miR-1632 for DNMT3B, and each was designed to be co-expressed under control of the CMV promoter (pcDNA-DsRed-miRNA). [score:2]
org/miRDB/) revealed putative binding sites for miR-148a and miR-1612 (for DNMT1) ; miR-1596, miR-1687, miR-1741, and miR-1749 (for DNMT3A) ; and miR-16c, miR-222, and miR-1632 (for DNMT3B). [score:1]
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7
[+] score: 5
This is the case of the miRNA mir148A which promotes cell proliferation and cell cycle progression by targeting p27, a key inhibitor of the cell cycle. [score:5]
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8
[+] score: 4
The following 15 miRNAs were dominantly expressed in the two libraries: gga-miR-10a, gga-miR-146c, gga-miR-101, gga-miR-21, gga-let-7a, gga-let-7b, gga-let-7c, gga-let-7j, gga-let-7f, gga-let-7 k, gga-miR-30a-5p, gga-miR-30e, gga-miR-148a, gga-miR-100 and gga-miR-126. [score:3]
Furthermore, gga-miR-101, gga-miR-1a, gga-miR-146c, gga-miR-148a, gga-miR-126, gga-miR-26a and gga-miR-30d were abundant in our sequencing libraries, as has been shown in other animal gonads [25, 27, 28]. [score:1]
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9
[+] score: 3
This is consistent with the previous report, in which miR-148a was identified as the most abundant miRNA in porcine livers of different breeds [43]. [score:1]
This result indicated miR-148a might play important roles in liver. [score:1]
Among the identified miRNAs in this study, gga-miR-148a is the most abundant miRNA in chicken hepatocytes. [score:1]
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10
[+] score: 3
Other miRNAs from this paper: gga-mir-155, gga-mir-10b, gga-mir-137, gga-mir-21
Gga-miR-148a displayed increased H3K4me3 marks in infected birds from the resistant line at 10 dpi, while no changes were evident at the earlier time-point (Figure  2B). [score:1]
Close examination of the list of DMR -associated miRNAs revealed several immune-related miRNAs, e. g. gga-miR-155, gga-miR-148a (H3K4me3), gga-miR-10b and gga-miR-137 (H3K27me3). [score:1]
A) Gga-mir-155, B) Gga-mir-148a and C) Gga-mir-21 display significantly increased H3K4me3 marks in the resistant line L6 [3] at the latent stage of infection. [score:1]
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11
[+] score: 3
Other chicken miRNAs that are expressed at high levels in IAH30 cells include gga-miR-24 (5.5%), gga-miR-27b (4%), gga-miR-19b (3.9%), gga-miR-20a (3.9%), gga-miR-148a (3.7%), gga-miR-23b (3%), and gga-miR-92 (3%). [score:3]
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12
[+] score: 3
L. monocytogenes infection reduced expression of miR-143, miR-148a, miR-200b, miR-200c, and miR-378 in intestine upon L. monocytogenes infection (7). [score:3]
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13
[+] score: 3
The miRNAs predicted to target these genes were mainly miR-21-5p, miR-100-5p, miR-148a-3p, let-7f-5p, and miR-10a-5p. [score:3]
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14
[+] score: 3
miRNAs Normalized Reads Total Reads WRRh WRRl XHh XHl gga-miR-133a 3,558,683 3,069,071 1,997,286 2,607,787 11,232,827 gga-miR-133c 3,350,936 2,885,440 1,878,925 2,449,209 10,564,510 gga-miR-133b 3,326,848 2,864,578 1,864,721 2,431,274 10,487,421 gga-let-7a 1,699,621 1,513,865 857,210 1,133,532 5,204,228 gga-miR-22-3p 1,333,233 1,145,421 712,464 988,186 4,179,304 gga-miR-30a-5p 1,213,468 1,148,128 790,893 930,507 4,082,996 gga-miR-26a 1,212,635 1,054,689 691,456 1,006,522 3,965,302 gga-miR-30d 851,887 813,262 583,932 667,002 2,916,083 gga-miR-181a-6p 918,452 836,452 485,661 650,836 2,891,401 gga-miR-10a-5p 943,686 782,180 420,809 663,401 2,810,076 gga-miR-10b 911,725 757,564 398,852 633,567 2,701,708 gga-miR-30e 799,679 730,832 501,718 596,218 2,628,447 gga-let-7j 848,972 756,205 428,182 566,165 2,599,524 gga-let-7f 398,292 363,598 206,995 274,333 1,243,218 gga-miR-148a 288,585 300,432 144,015 180,973 914,005 gga-miR-146c-5p 224,147 207,782 171,443 132,712 736,084 gga-let-7k 211,853 206,518 118,297 155,412 692,080 gga-let-7c 242,661 189,820 111,118 139,257 682,856 gga-miR-199-3p 168,417 152,158 75,346 121,460 517,381 gga-miR-126-5p 139,914 109,805 89,607 86,681 426,007 Differentially expressed miRNAs were identified by DEGseq analysis (fold change > 1.5 or < 0.66; p-value < 0.05; q-value < 0.01), as a result, 200, 279, 257 and 297 miRNAs were detected in four comparisons of WRRh vs. [score:3]
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15
[+] score: 2
gga-miR-221, gga-miR-222, gga-miR148, gga-miR-27b, gga-miR-34a and gga-miR-130a, which are related to differentiation and maturation, could also further influence the function of mature DCs. [score:1]
As shown in Fig. 4, gga-miR-221, gga-miR-125b, gga-miR-211, gga-miR-222a, gga-miR-193b, gga-miR-148a, gga-miR-27b, gga-miR-34a and gga-miR-130a were quantified by qRT-PCR, and these results were consistent with the sequencing analysis. [score:1]
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16
[+] score: 2
Other miRNAs from this paper: hsa-mir-148a
Xu Q, Liu LZ, Yin Y, He J, Li Q, Qian X, et al. Regulatory circuit of PKM2/NF-κB/miR-148a/152-modulated tumor angiogenesis and cancer progression. [score:2]
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17
[+] score: 1
Furthermore, gga-miR-7, gga-miR-148a-3p, gga-miR-146c-5p, gga-miR-125b-5p, gga-miR-30d, gga-miR-153-3p and gga-miR-126-3p were abundant in our sequencing libraries and have been shown to occur in other animals [15, 69, 73, 74]. [score:1]
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18
[+] score: 1
MiR-18, miR-98, miR-128, miR-135, and miR-148 affect ovarian cell steroidogenesis, including the production of progesterone, testosterone, and estradiol [17]. [score:1]
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19
[+] score: 1
MiR-128-1 and miR-148a reduce hepatic levels of proteins involved in lipid trafficking and metabolism and levels of circulating cholesterol and TG [28]. [score:1]
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