sort by

13 publications mentioning gga-mir-181b-1

Open access articles that are associated with the species Gallus gallus and mention the gene name mir-181b-1. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 24
Let-7b -mediated regulation of GHR expressionThe miRNAs involved in the regulation of GHR were let-7b, miR-15c (miR-16, miR-16c), and miR-181b (Additional file 3: Table S3). [score:5]
In 14-day-old embryos, expression of both miR-1623 and miR-181b was significantly down-regulated in dwarf chickens compared with normal chickens. [score:5]
At the same developmental stages, different expression profiles in skeletal muscles of dwarf and normal chickens occurred for four miRNAs (miR-1623, miR-181b, let-7b, and miR-128). [score:4]
However, the target sites of miR-15c, miR-16, miR-16c and miR-181b were far apart from the GHR region. [score:3]
But the target locations of miR-16, miR-16c and miR-181b were distant from the deleted region. [score:3]
Four miRNAs, let-7b, miR-16, miR-16c, and miR-181b, are involved in the regulation of GHR. [score:2]
The miRNAs involved in the regulation of GHR were let-7b, miR-15c (miR-16, miR-16c), and miR-181b (Additional file 3: Table S3). [score:2]
[1 to 20 of 7 sentences]
2
[+] score: 22
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-15a, hsa-mir-16-1, hsa-mir-17, hsa-mir-18a, hsa-mir-19a, hsa-mir-19b-1, hsa-mir-19b-2, hsa-mir-20a, hsa-mir-21, hsa-mir-24-1, hsa-mir-24-2, hsa-mir-92a-1, hsa-mir-92a-2, hsa-mir-106a, hsa-mir-16-2, hsa-mir-181a-2, hsa-mir-181b-1, hsa-mir-181a-1, hsa-mir-221, hsa-mir-222, hsa-mir-223, hsa-let-7g, hsa-let-7i, hsa-mir-15b, hsa-mir-23b, hsa-mir-27b, hsa-mir-122, hsa-mir-125b-1, hsa-mir-140, hsa-mir-125b-2, hsa-mir-136, hsa-mir-146a, hsa-mir-150, hsa-mir-206, hsa-mir-155, hsa-mir-181b-2, hsa-mir-106b, hsa-mir-302a, hsa-mir-34b, hsa-mir-34c, hsa-mir-302b, hsa-mir-302c, hsa-mir-302d, hsa-mir-367, gga-let-7i, gga-let-7a-3, gga-let-7b, gga-let-7c, gga-mir-125b-2, gga-mir-155, gga-mir-222a, gga-mir-221, gga-mir-92-1, gga-mir-19b, gga-mir-20a, gga-mir-19a, gga-mir-18a, gga-mir-17, gga-mir-16-1, gga-mir-15a, gga-mir-1a-2, gga-mir-206, gga-mir-223, gga-mir-106, gga-mir-302a, gga-mir-181a-1, gga-mir-16-2, gga-mir-15b, gga-mir-140, gga-let-7g, gga-let-7d, gga-let-7f, gga-let-7a-1, gga-mir-146a, gga-mir-181b-2, gga-mir-181a-2, gga-mir-1a-1, gga-mir-1b, gga-let-7a-2, gga-mir-34b, gga-mir-34c, gga-let-7j, gga-let-7k, gga-mir-23b, gga-mir-27b, gga-mir-24, gga-mir-122-1, gga-mir-122-2, hsa-mir-429, hsa-mir-449a, hsa-mir-146b, hsa-mir-507, hsa-mir-455, hsa-mir-92b, hsa-mir-449b, gga-mir-146b, gga-mir-302b, gga-mir-302c, gga-mir-302d, gga-mir-455, gga-mir-367, gga-mir-429, gga-mir-449a, hsa-mir-449c, gga-mir-21, gga-mir-1458, gga-mir-1576, gga-mir-1612, gga-mir-1636, gga-mir-449c, gga-mir-1711, gga-mir-1729, gga-mir-1798, gga-mir-122b, gga-mir-1811, gga-mir-146c, gga-mir-15c, gga-mir-449b, gga-mir-222b, gga-mir-92-2, gga-mir-125b-1, gga-mir-449d, gga-let-7l-1, gga-let-7l-2, gga-mir-122b-1, gga-mir-122b-2
Clusters mir-16-1-mir-15a, let-7f-let-7a-1, mir-181a-1-mir-181b-1, let-7j-let-7k, mir-23b-mir-27b-mir-24, and mir-16-2-mir-15b were down-regulated in lungs and mir-181a-1-mir-181b-1 was also down-regulated in tracheae with AIV infection. [score:7]
Only miR-181b was expressed in the macrophage cell line HD11 as well in the spleen adherent cells and that its expression increased after activation by LPS or CD40-ligand [42]. [score:5]
The mir-181a-1-mir181b-1 cluster was significantly down-regulated in both infected lungs and tracheae. [score:4]
These results suggest that miR-181a and miR-181b may be strong miRNA candidates that regulate host response to AIV infection, and warrant further investigation of their targets and regulation mechanism in chickens. [score:3]
In the current study, miR-181b had same expression pattern with miR-181a in both lung and trachea comparisons. [score:3]
[1 to 20 of 5 sentences]
3
[+] score: 20
For example, differences in the transcripts level of two microRNA were detected (Table S2 in): mir181-b was downregulated in the 3NF/pCI, while mir1186 was downregulated in K3/pCI. [score:7]
Moreover, miR-181b-1 was downregulated only in 3NF/pCI group, while miR-1186 was downregulated only in K3/pCI. [score:7]
Interestingly, mir181-b inhibits the expression of importin-α3 that is crucial for translocation of NF-κB from cytoplasm to nucleus. [score:5]
The level of mir181-b is reduced after proinflamatory stimulation, e. g., by TNF-α and the transcription of NF-κB -dependent genes can be activated (33). [score:1]
[1 to 20 of 4 sentences]
4
[+] score: 17
All members of the miR-15, miR-181, and miR-29 families were down-regulated in L30 compared with L20, whereas the other families included members that were either up- or down-regulated. [score:6]
MiR-101-3p (−2.1-fold) and miR-15c-5p (−1.4-fold) had the most target genes followed by miR-15a, miR-16-5p, miR-214, miR-16c-5p, and miR-181b-5p (Supplementary Table S4), and these miRNAs were all down-regulated in L30 compared with L20. [score:5]
In this study, FADS1 was targeted by miR-365-3p, miR-218-5p, miR-181a-5p, miR-181b-5p, miR-29a-3p, and miR-23b-3p, whereas FADS2 was targeted by miR-30c-1-3p. [score:5]
Seven conserved families all were DE with P ≤ 0.05, including let-7 (let-7a, -7b, -7c,-7f, -7g, -7i, -7j, and -7k), miR-130 (miR-130a, and -130b), miR-146 (miR-146a, -146b, and -146c), miR-15 (miR-15a, -15b, and -15c), miR-181 (miR-181a and -181b), miR-29 (miR-29a, -29b and -29c), and miR-30 (miR-30a, -30b, -30c, -30d, and -30e). [score:1]
[1 to 20 of 4 sentences]
5
[+] score: 13
Similarly, some other highly expressed differential miRNAs (FDR < 0.05), such as miR-107-3p, let-7b, and miR-181b, have all been proved to take part in the regulation of postnatal liver development or metergasis process 22, 24, 25. [score:5]
By using three different endogenous control miRNAs (U6, 5S, and 18S), the results have all showed that two miRNAs (gga-miR-181b-5p_R + 1 and gga-miR-30b-5p) had significantly lower expression levels in matured livers than the postnatal livers, and the expression level of another four miRNAs (gga-let-7a-5p, gga-miR-2954_R + 2, gga-miR-21-5p, and gga-miR-122-5p) were significantly increased in matured livers (Fig.   3), which were consistent with the miRNA-seq data. [score:5]
Wang B miR-181b promotes hepatic stellate cells proliferation by targeting p27 and is elevated in the serum of cirrhosis patientsBiochem Biophys Res Commun. [score:3]
[1 to 20 of 3 sentences]
6
[+] score: 9
These miRNAs were divided into three groups according to their expression levels in the fat broiler line, 4 highly expressed (gga-miR-21, gga-miR-148a, gga-miR-103, gga-miR-101) (2 [-ΔCt] >0.7), 4 moderately expressed (gga-miR-100, gga-miR-146a, gga-miR-92, gga-miR-2188) (0.7>2 [-ΔCt]>0.08), and 7 lowly expressed (gga-miR-1a, gga-miR-130a, gga-miR-221, gga-miR-19a, gga-miR-181b, gga-miR-458, gga-miR-17–3p) (2 [-ΔCt]<0.08) (Table 2). [score:9]
[1 to 20 of 1 sentences]
7
[+] score: 6
Expression of miR-181 isoforms, miR-181a and miR-181b, are induced upon initiation of myogenesis and they participate in the regulation of myoblast differentiation by repressing HoxA-11 protein levels [24]. [score:4]
In addition to miR-206, miR-1 and miR-181, nine other miRNAs among the most abundant in these libraries (miR-221, miR-222, miR-21, miR-103, miR-130, miR-99, miR-30, miR20, and miR128) have been implicated in the proliferation and differentiation of muscle cells (Table 1) [15, 19, 33]. [score:1]
Two other myomiRs, miR-1 [19] and miR-181 [24], were high-count sequences in both libraries (Table 1). [score:1]
[1 to 20 of 3 sentences]
8
[+] score: 5
Naguibneva I. Ameyar-Zazoua M. Polesskaya A. Ait-Si-Ali S. Groisman R. Souidi M. Cuvellier S. Harel-Bellan A. The microRNA miR-181 targets the homeobox protein Hox-A11 during mammalian myoblast differentiation Nat. [score:3]
miR-181b and miR-199 are also involved in the regulation of myogenesis [61, 62]. [score:2]
[1 to 20 of 2 sentences]
9
[+] score: 4
During the same developmental stage, miR-1623, miR-181b, let-7b, and miR-128 were differentially expressed in the skeletal muscle of dwarf and normal chickens [10]. [score:4]
[1 to 20 of 1 sentences]
10
[+] score: 4
Two members of miR-181 (miR-181a, 181b) were down-regulated in glioma specimens and glioma cell lines [37], as well as pituitary adenomas [38] and lymphocytic leukemia [39]. [score:4]
[1 to 20 of 1 sentences]
11
[+] score: 3
Two miRNAs, miR-1623 and miR-181b, are differentially expressed in 14-day-old embryos of diverse growth-rate dwarf and normal chickens [83]. [score:3]
[1 to 20 of 1 sentences]
12
[+] score: 2
Figure 2The muscle specific miRNAs (myo-miR), miR-133a/b, miR-206, miR-486, miR-26a, miR-27b, miR-378, miR-148a and miR-181 were highly enriched in skeletal muscle and play key roles in skeletal muscle metabolism [11]. [score:1]
Figure 2 The muscle specific miRNAs (myo-miR), miR-133a/b, miR-206, miR-486, miR-26a, miR-27b, miR-378, miR-148a and miR-181 were highly enriched in skeletal muscle and play key roles in skeletal muscle metabolism [11]. [score:1]
[1 to 20 of 2 sentences]
13
[+] score: 1
The other seven miRNAs (miR-460B-5P, miR-383-5p, miR-181b-5p, gga-let-7b, miR-301b-3p, miR-10a-3p and miR-217-5p) created the other half of the network, interacting with 13 other protein-coding genes that are related to the immune system, hemarthrosis, arteriosclerosis obliterans, apoptosis, survival caspase cascade and muscular dystrophy. [score:1]
[1 to 20 of 1 sentences]