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5 publications mentioning aga-mir-8

Open access articles that are associated with the species Anopheles gambiae and mention the gene name mir-8. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 18
Other miRNAs from this paper: hsa-mir-33a, hsa-mir-92a-1, hsa-mir-92a-2, dme-mir-1, dme-mir-8, dme-mir-11, hsa-mir-34a, hsa-mir-210, dme-mir-184, dme-mir-275, dme-mir-92a, dme-mir-276a, dme-mir-277, dme-mir-33, dme-mir-281-1, dme-mir-281-2, dme-mir-34, dme-mir-276b, dme-mir-210, dme-mir-92b, dme-bantam, dme-mir-309, dme-mir-317, hsa-mir-1-2, hsa-mir-184, hsa-mir-190a, hsa-mir-1-1, hsa-mir-34b, hsa-mir-34c, aga-bantam, aga-mir-1, aga-mir-184, aga-mir-210, aga-mir-275, aga-mir-276, aga-mir-277, aga-mir-281, aga-mir-317, aga-mir-92a, aga-mir-92b, hsa-mir-92b, hsa-mir-33b, hsa-mir-190b, dme-mir-190, dme-mir-957, dme-mir-970, dme-mir-980, dme-mir-981, dme-mir-927, dme-mir-989, dme-mir-252, dme-mir-1000, aga-mir-1174, aga-mir-1175, aga-mir-34, aga-mir-989, aga-mir-11, aga-mir-981, aga-mir-1889, aga-mir-1890, aga-mir-1891, aga-mir-190, aga-mir-927, aga-mir-970, aga-mir-957, aga-mir-1000, aga-mir-309, cqu-mir-1174, cqu-mir-281-1, cqu-mir-1, cqu-mir-275, cqu-mir-957, cqu-mir-277, cqu-mir-252-1, cqu-mir-970, cqu-mir-317-1, cqu-mir-981, cqu-mir-989, cqu-mir-1175, cqu-mir-276-1, cqu-mir-276-2, cqu-mir-276-3, cqu-mir-210, cqu-mir-92, cqu-mir-190-2, cqu-mir-190-1, cqu-mir-1000, cqu-mir-11, cqu-mir-8, cqu-bantam, cqu-mir-1891, cqu-mir-184, cqu-mir-1890, cqu-mir-980, cqu-mir-33, cqu-mir-2951, cqu-mir-2941-1, cqu-mir-2941-2, cqu-mir-2952, cqu-mir-1889, cqu-mir-309, cqu-mir-252-2, cqu-mir-281-2, cqu-mir-317-2, aga-mir-2944a-1, aga-mir-2944a-2, aga-mir-2944b, aga-mir-2945, aga-mir-33, aga-mir-980
Furthermore, nucleotide diversity in the terminal loop for miR-8, a miRNA known to be involved in Wnt signaling in the fly [21, 36], may help fine tune not only miRNA strand selection but also the miRNA sequence itself, thereby also fine tuning miRNA target regulation. [score:4]
Additionally, the prevalence of the miRNA* strand for several miRNAs, such as miR-1889, miR-8, and bantam, expands the potential of miRNA regulation in an organism by adding to the number of possible miRNA seeds and thus adding new mRNA targets. [score:4]
In Drosophila, miR-277 has predicted targets in metabolic pathways [20] while miR-8 plays a role in Wnt signaling [36]. [score:3]
albopictus library, the ratio of 5p:3p miRNA reads was 1,244 miR-8-5p: 3,002 miR-8-3p (ratio of 0.41) (Table 1). [score:1]
quinquefasciatus miR-8-3p. [score:1]
miRNA* strands for several miRNAs, including miR-8, miR-1889, and bantam, were sequenced a significant number of times, and thus are annotated with 5p or 3p (Tables 1, 2). [score:1]
Intriguingly, all nucleotide differences for miR-8 affect only the terminal loop of the pre-miRNA hairpin, which alters the pairing at the immediate base of the terminal loop. [score:1]
aegypti miR-8 pre-miRNA shares 98% and 92% sequence identity with the miR-8 pre-miRNA in Cx. [score:1]
Interestingly, for miR-8 in the Ae. [score:1]
albopictus C710 cells, these two species shared five out of the top ten most frequently occurring miRNAs: miR-184, miR-317, miR-277, miR-275, and miR-8 (Tables 1, 2). [score:1]
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2
[+] score: 14
Strikingly, in A. gambiae, 80% of nontemplate-directed urydilated reads derived from miR-8. The number of described 3’ additions in this study might be significantly underestimated since certain adenine and uracil additions map to adjacent genomic sequence of the pre-miRNA (e. g. miR-281, let-7 or bantam) and therefore, it was not possible to discern unambiguously between template- and nontemplate-directed additions. [score:3]
We identified bantam, miR-263a, miR-8, miR-10, miR-184 and miR-281 as the most abundantly expressed miRNAs in A. gambiae (Additional file 1: Figure S2). [score:3]
Strikingly, more than 80% of detected non-template directed uracil additions were associated with miR-8 (Figure  3G, E). [score:2]
In addition, the ecdysone-responsive Drosophila miR-8 regulates insulin signaling and innate immune homeostasis [47, 48]. [score:2]
Nevertheless, the detected 3’ extensions of miR-8 and bantam might be a signature of their activity in the complex regulatory network of insulin and ecdysone signaling in A. gambiae females triggered by blood meal intake. [score:2]
Such modifications were mostly associated with miR-11, miR-14, miR-317, miR-277, miR-184, miR-8, miR-92b and miR-989. [score:1]
Functions of the most abundantly tailed miR-8, bantam and miR-281 are not known yet in A. gambiae. [score:1]
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3
[+] score: 4
For example, miR-315 and miR-8 regulate components of the Wg pathway, while miR-1 and miR-7 regulate N pathway components during fly development (reviewed by [136]). [score:4]
[1 to 20 of 1 sentences]
4
[+] score: 1
The copy numbers of ast-miR-8*, and ast-mir-277* are less than those of ast-miR-8 and ast-miR-277, respectively. [score:1]
[1 to 20 of 1 sentences]
5
[+] score: 1
The miR and miR* strands of a few other miRNAs (e. g., bantam and miR-8) were present in comparable levels in the Ago1 complex. [score:1]
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