1 publications mentioning dre-mir-301b

Open access articles that are associated with the species Danio rerio and mention the gene name mir-301b. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

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Totally, the final results included 9 downregulated miRNAs (dre-miR-142a-3p, dre-miR-142b-5p, dre-miR-144-3p, dre-miR-146a, dre-miR-190a, dre-miR-219-5p, dre-miR-301b-3p, dre-miR-459-5p and rno-miR-33-5p) and 3 upregulated miRNAs (dre-miR-735-3p, dre-miR-735-5p and mmu-miR-6240).

In general, dre-miR-301b, -142a, -144, and rno-miR-33, were highly focused in network of downregulated miRNAs, while dre-miR-735 and mmu-miR-6240 were in network of upregulated miRNAs.

MiR-301 also regulated the expression of key proteins involved in cholesterol homeostasis and blood lipid levels [27], consistent with what was indicated in S3 Fig. Although the research realm of miR-142a centered on cardiovascular and immune system [28, 29], evidences suggested its renal -associated actions [30].

One of them, miR-301b, belonged to miR-130 family, which was regarded as an oncogene and abnormally expressed in lung, breast and many other cancers [24– 26].

The utmost concern about miR-33 was its ability to regulate cellular cholesterol transport and maintain plasma HDL levels [32], which highly related with the physiological role of miR-301b.