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15 publications mentioning hsa-mir-492

Open access articles that are associated with the species Homo sapiens and mention the gene name mir-492. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 15
Similarly, the most highly expressed miRNAs in normal-like/claudin-low cell lines were hsa-miR-22, hsa-miR-532-3p, hsa-miR-125b, hsa-miR-501-5p, and hsa-miR-155*, whereas in basal-like cell lines miRNAs of the miR-200 family (hsa-miR-492, hsa-miR-26b, hsa-miR-617, hsa-miR-155) were highly expressed (fold change ≥ 2) (see Table S9 in Additional file 1). [score:5]
The hsa-miR-492 miRNA has been shown to be processed from the keratin 19 gene and upregulated in metastatic hepatoblastoma [43]. [score:4]
Among these potentially novel ER-related miRNAs, four miRNAs (hsa-miR-26a, hsa-miR-92b, hsa-miR-191, hsa-miR-492) appear to show consistently higher expression across all the ER -positive cell lines (fold change ≥ 1.5), and as yet only hsa-miR-26a has been implicated in breast carcinogenesis whereas hsa-miR-26a and hsa-miR-92b have also been implicated in brain tumors [39, 40]. [score:3]
Another group of 17 miRNAs (hsa-miR-575, hsa-miR-155, hsa-miR-26b, hsa-miR-200a, hsa-miR-200b, hsa-miR-141, hsa-miR-200c, hsa-miR-190b, hsa-miR-492, hsa-miR-640, hsa-miR-196a, hsa-miR-29c, hsa-miR-93, hsa-miR-193a-3p, hsa-miR-191, hsa-miR-26a, hsa-miR-182) showed significantly higher expression in the major cluster compared with the other miRNAs (fold change ≥ 1.5) (Figure 2, bottom red box). [score:2]
The other two miRNAs (hsa-miR-191, hsa-miR-492) have been linked to hepatic cancer. [score:1]
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[+] score: 13
Predicted targets for the top 5 annotated miRNA in exosomes (miR-663, miR-503, miR-492, miR-498 and miR-671–5p) were searched using TargetScan and subsequently the target mRNAs were analysed by IPA software to determine predicted canonical pathways, networks and biofunctions regulated by the exosomal miRNAs (Fig. 5 and Additional Information, Table S6. [score:8]
TargetScanHuman 5.1 was applied to predict mRNA targets for the top 5 annotated microRNAs detected in exosomes (miR-663, miR-503, miR-492, miR-498 and miR-671–5p), which generated a list of 500 mRNA. [score:5]
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[+] score: 11
Considering a fold-change of 1.5, only three miRNA were downregulated following TSH addition (hsa-miR-492 and hsa-miR-584 at 48 h and has-miR-138 at 72 h) and no miRNA was upregulated. [score:7]
For the TSH treatment, no miRNA was modulated before 48 hours, and 2 miRNA were downregulated (hsa-miR-492 and hsa-miR-584) at that time. [score:4]
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[+] score: 9
Other miRNAs from this paper: hsa-mir-622, hsa-mir-4788, hsa-mir-7161
Shen F. Cai W. -S. Feng Z. Li J. -L. Chen J. -W. Cao J. Xu B. MiR-492 contributes to cell proliferation and cell cycle of human breast cancer cells by suppressing SOX7 expressionTumour Biol. [score:4]
Primate-specific miR-492 may be expressed from both KRT19 gene and retrogene loci [141, 142]. [score:3]
Devor E. J. Primate microRNAs miR-220 and miR-492 lie within processed pseudogenesJ. [score:1]
Interestingly, hs-miR-492 was proposed to play a role in the progression of hepatoblastoma [142] and was found to be a proto-oncogenic miRNA, acting as a cell proliferation promoter in breast cancer [143]. [score:1]
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[+] score: 6
miR-492 and miR-548d were both up-regulated (4.9 and 3.2 times respectively) in TSI individuals compared to controls whilst 3 miR (miR-508, miR-509 and miR-664) were >3 fold down-regulated. [score:6]
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[+] score: 6
Van Jaarsveld et al. compared the miR expression profiles of cisplatin-sensitive and -resistant ovarian cancer cells, revealing that high expression of miR-141, miR-200c, miR-215, and miR-421 and low expression of miR-492-5p correlated with increased cisplatin resistance [61]. [score:6]
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[+] score: 4
Shen F, Cai WS, Feng Z, Li JL, Chen JW, Cao J, et al. MiR-492 contributes to cell proliferation and cell cycle of human breast cancer cells by suppressing SOX7 expression. [score:4]
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[+] score: 3
Furthermore, SOX7 has been supposed to be a suppressor to miR-492, which represents a potential onco-miR and participates in breast cancer carcinogenesis 41. [score:3]
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[+] score: 2
Ying C., Sui-Xin L., Kang-Ling X., Wen-Liang Z., Lei D., Yuan L., Fan Z., Chen Z. (2014) MicroRNA-492 reverses high glucose -induced insulin resistance in HUVEC cells through targeting resistin. [score:2]
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[+] score: 1
$ mir-492 rs2289030 and deviated from HWE in controls. [score:1]
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[+] score: 1
Furthermore, four novel microRNA families detected here were also specific to primate genomes (hsa-mir-1826, hsa-mir-1827, hsa-mir-3185 and hsa-mir-492) (Figure 2a). [score:1]
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[+] score: 1
Other miRNAs from this paper: hsa-mir-205, hsa-mir-210, hsa-mir-1247
In pancreatic juice, increased levels of miR-205, miR-210, miR-492, and miR-1247 are associated with poor prognosis for pancreatic adenocarcinoma [30]. [score:1]
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[+] score: 1
Moreover, Devor et al. [226] found out that primate-specific miRNAs, miR-220 and miR-492, each lie within a processed pseudogene. [score:1]
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[+] score: 1
2 −13.24 1.43E-09 hsa-miR-492 12q22 −7.77 5.38E-08 hsa-miR-874 5q31.2 −6.76 1.53E-08hsa-miR-30b * 8q24.22 −6.54 2.73E-09 hsa-miR-602 9q34.3 −5.75 2.63E-08 * hsa-miR-124 is transcribed from three chromosomal locations, but the mature sequences are the same. [score:1]
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[+] score: 1
The RT-PCR data indicated that over 83% (2 out of 24 genes and time points, e. g., hsa-miR-492 in 5 cGy and 2 Gy groups) of the ratios generated by microarray hybridizations were valid. [score:1]
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