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9 publications mentioning hsa-mir-648

Open access articles that are associated with the species Homo sapiens and mention the gene name mir-648. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 15
Other miRNAs from this paper: hsa-mir-197, hsa-mir-155
The target genes of miR-648 are listed in Figure  8. With the exception of BCL11A, the other nine genes are exclusively regulated by miR-648. [score:4]
Among these two miRNAs, miR-155 downregulation in PCa was in agreement with the results of a previous report [45], whereas miR-648 was identified as a novel PCa miRNA biomarker by our study. [score:4]
Figure 8 Target genes of novel identified biomarker - miR-648 (NOD = 9). [score:3]
miR-648 was identified as a novel candidate PCa miRNA biomarker. [score:1]
To further investigate the activities of PCa miRNA biomarkers predicted by our approach, we randomly selected three miRNAs (miR-155, miR-648, and miR-197) to detect differences in their expression between PCa tissues and benign prostatic hyperplasia tissues by q-PCR technology. [score:1]
These evidences support that miR-648 could be involved in PCa and act as a novel molecular biomarker for PCa diagnosis. [score:1]
In vitro q-PCR experiments and functional analysis further verified the accuracy of our predictions and miR-648 was identified as a novel candidate PCa miRNA biomarker. [score:1]
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[+] score: 11
The expression levels of miR-1225-5p, miR-1909-5p, miR-512-5p, miR-3927, miR-1203, miR-2110, miR-501-5p, miR-648, miR-4729, miR-4475, miR-1914-3p and miR-5002-5p were downregulated in the children with CPHD. [score:6]
However, the expression levels of miR-1225-5p, miR-1909-5p, miR-512-5p, miR-3927, miR-1203, miR-2110, miR-501-5p, miR-648, miR-4729, miR-4475, miR-1914-3p and miR-5002-5p were downregulated (Fig. 2B) (P<0.05) in the children with CPHD compared with the normal controls. [score:5]
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[+] score: 10
Out of the eight miRNAs, miR-648 was up-regulated and the seven remaining miRNAs were down regulated (miR-744-5p, miR-193b-3p, miR-212-3p, miR-143-3p, miR-93-5p, miR-423-3p and miR-766-3p). [score:5]
We used miScript Primer Assays for 9 miRNAs (miR-744-5p, miR-648, miR-193b-3p, miR-212-3p, miR-143-3p, miR-93-5p, miR-222-3p, miR-423-3p and miR-766-3p) and QuantiTect Primer assays for 9 target genes (CDKN1A, MYC, PTEN, ESR1, ETS1, SOD2, MGMT, KRAS and HNF4A) (Qiagen, Hilden, Germany) to validate the different expression levels of the miRNA and their target genes, which are determined by miRTargetLink prediction software. [score:5]
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[+] score: 5
Further assaying these three miRNAs in individual serum sample showed that miR-648 and miR-4298 had relatively narrow expression ranges, with Ct values ranging from 18.5 to 19.4, and 20.0 to 21.4, respectively (Figure 6B). [score:2]
Although miR-16 [40], [41] and miR-648 [42] are known to be present at high levels in serum, this is the first report that miR-4298 also exists abundantly in the circulation. [score:1]
Among them, miR-648, miR-4298, and miR-16 were among the most abundant circulating miRNAs, with a Ct value of 18.9, 20.8, and 22.2, respectively. [score:1]
B: Box-whisker plots of the three most abundant miRNAs, namely miR-648, miR-4298 and miR-16 in each healthy serum sample (n = 40). [score:1]
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[+] score: 5
While miR-21, miR-30a and miR-373 were expressed in all 7 tissues including testis, kidney, lung, spleen, heart, liver and skeletal muscle, miR-422, miR-28, miR-379, miR-431 and miR-648 demonstrated more restricted expression patterns (Figure 2). [score:5]
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[+] score: 3
Other miRNAs found differentially expressed in both tissues and cell lines are miR-146b, miR-508, miR-106b, miR-134, miR-155, miR-346, miR-422a, miR-424, miR-519a, miR-648, miR-662. [score:3]
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[+] score: 3
While miR648 and 373 were reportedly expressed in the rhesus liver [37], these miRNAs were not detected in baboon liver using miRNA arrays or RT-PCR. [score:3]
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[+] score: 2
In our preliminary test, however, we found that miR-648 and miR-1208 could not be readily detected by PCR, hence we did not include them in further analysis. [score:1]
The sequence for miR-648 was aagugugcagggcacuggu. [score:1]
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[+] score: 1
Other miRNAs from this paper: hsa-mir-25, hsa-mir-28, hsa-mir-95, mmu-mir-151, mmu-mir-290a, mmu-mir-297a-1, mmu-mir-297a-2, mmu-mir-130b, mmu-mir-340, mmu-mir-25, mmu-mir-28a, hsa-mir-130b, hsa-mir-367, hsa-mir-372, hsa-mir-378a, mmu-mir-378a, hsa-mir-340, hsa-mir-151a, mmu-mir-466a, mmu-mir-467a-1, hsa-mir-505, hsa-mir-506, mmu-mir-367, hsa-mir-92b, hsa-mir-548a-1, hsa-mir-548b, hsa-mir-548a-2, hsa-mir-548a-3, hsa-mir-548c, hsa-mir-548d-1, hsa-mir-548d-2, hsa-mir-659, hsa-mir-421, hsa-mir-151b, hsa-mir-1271, hsa-mir-378d-2, mmu-mir-467b, mmu-mir-297b, mmu-mir-505, mmu-mir-297a-3, mmu-mir-297a-4, mmu-mir-297c, mmu-mir-421, mmu-mir-466b-1, mmu-mir-466b-2, mmu-mir-466b-3, mmu-mir-466c-1, mmu-mir-466e, mmu-mir-466f-1, mmu-mir-466f-2, mmu-mir-466f-3, mmu-mir-466g, mmu-mir-466h, mmu-mir-467c, mmu-mir-467d, mmu-mir-92b, mmu-mir-466d, hsa-mir-297, mmu-mir-467e, mmu-mir-466l, mmu-mir-669g, mmu-mir-466i, mmu-mir-466f-4, mmu-mir-466k, mmu-mir-467f, mmu-mir-466j, mmu-mir-467g, mmu-mir-467h, mmu-mir-1195, hsa-mir-548e, hsa-mir-548j, hsa-mir-1285-1, hsa-mir-1285-2, hsa-mir-1289-1, hsa-mir-1289-2, hsa-mir-548k, hsa-mir-1299, hsa-mir-548l, hsa-mir-1302-1, hsa-mir-1302-2, hsa-mir-1302-3, hsa-mir-1302-4, hsa-mir-1302-5, hsa-mir-1302-6, hsa-mir-1302-7, hsa-mir-1302-8, hsa-mir-548f-1, hsa-mir-548f-2, hsa-mir-548f-3, hsa-mir-548f-4, hsa-mir-548f-5, hsa-mir-1255a, hsa-mir-548g, hsa-mir-548n, hsa-mir-548m, hsa-mir-548o, hsa-mir-1268a, hsa-mir-548h-1, hsa-mir-548h-2, hsa-mir-548h-3, hsa-mir-548h-4, hsa-mir-548p, hsa-mir-548i-1, hsa-mir-548i-2, hsa-mir-548i-3, hsa-mir-548i-4, hsa-mir-1255b-1, hsa-mir-1255b-2, mmu-mir-1906-1, hsa-mir-1972-1, hsa-mir-548q, mmu-mir-466m, mmu-mir-466o, mmu-mir-467a-2, mmu-mir-467a-3, mmu-mir-466c-2, mmu-mir-467a-4, mmu-mir-466b-4, mmu-mir-467a-5, mmu-mir-466b-5, mmu-mir-467a-6, mmu-mir-466b-6, mmu-mir-467a-7, mmu-mir-466b-7, mmu-mir-467a-8, mmu-mir-467a-9, mmu-mir-467a-10, mmu-mir-466p, mmu-mir-466n, mmu-mir-466b-8, hsa-mir-3116-1, hsa-mir-3116-2, hsa-mir-3118-1, hsa-mir-3118-2, hsa-mir-3118-3, hsa-mir-548s, hsa-mir-378b, hsa-mir-466, hsa-mir-548t, hsa-mir-548u, hsa-mir-548v, hsa-mir-3156-1, hsa-mir-3118-4, hsa-mir-3174, hsa-mir-3179-1, hsa-mir-3179-2, hsa-mir-3179-3, hsa-mir-548w, hsa-mir-3156-2, hsa-mir-3156-3, hsa-mir-548x, mmu-mir-3470a, mmu-mir-3470b, mmu-mir-3471-1, mmu-mir-3471-2, hsa-mir-378c, hsa-mir-1972-2, hsa-mir-1302-9, hsa-mir-1302-10, hsa-mir-1302-11, mmu-mir-1906-2, hsa-mir-3683, hsa-mir-3690-1, hsa-mir-548y, hsa-mir-548z, hsa-mir-548aa-1, hsa-mir-548aa-2, hsa-mir-548o-2, hsa-mir-1268b, hsa-mir-378d-1, hsa-mir-378e, hsa-mir-548h-5, hsa-mir-548ab, hsa-mir-378f, hsa-mir-378g, hsa-mir-548ac, hsa-mir-548ad, hsa-mir-548ae-1, hsa-mir-548ae-2, hsa-mir-548ag-1, hsa-mir-548ag-2, hsa-mir-548ah, hsa-mir-378h, hsa-mir-548ai, hsa-mir-548aj-1, hsa-mir-548aj-2, hsa-mir-548x-2, hsa-mir-548ak, hsa-mir-548al, hsa-mir-378i, hsa-mir-548am, hsa-mir-548an, mmu-mir-28c, mmu-mir-378b, mmu-mir-28b, hsa-mir-548ao, hsa-mir-548ap, mmu-mir-466q, hsa-mir-548aq, hsa-mir-548ar, hsa-mir-548as, hsa-mir-548at, hsa-mir-548au, hsa-mir-548av, hsa-mir-548aw, hsa-mir-548ax, hsa-mir-378j, mmu-mir-378c, mmu-mir-378d, hsa-mir-548ay, hsa-mir-548az, hsa-mir-3690-2, mmu-mir-290b, hsa-mir-548ba, hsa-mir-548bb, hsa-mir-3179-4, mmu-mir-466c-3, hsa-mir-548bc, mmu-mir-1271
Exceptions to this were hsa-mir-130b and hsa-mir-648 that we classified as NRdmiRs, and hsa-mir-659 that was classified as a PRdmiR. [score:1]
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