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5 publications mentioning gga-mir-383

Open access articles that are associated with the species Gallus gallus and mention the gene name mir-383. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 99
To validate the downregulation of c DNMT3B at the post-transcription levels, the miRNAs, gga-miR-15c (target score: 74, seed location: 544 and 732), gga-miR-29b (target score: 62, seed location: 1223), gga-miR-383 (target score: 53, seed location: 996), and gga-miR-222 (target score: 50, seed location: 591) were selected for the c DNMT3B 3′-UTR based on an online database miRDB (Fig. 11A). [score:12]
Regulation of cDNMT3B using 3′UTR target miRNAsTo examine the regulation of c DNMT3B expression, we selected four miRNAs including gga-miR-15c (5′-UAG CAG CAC AUC AUG GUU UGU A-3′), gga-miR-29b (5′-UAG CAC CAU UUG AAA UCA GUG UU-3′), gga-miR-383 (5′-AGA UCA GAA GGU GAU UGU GGC U-3′), and gga-miR-222 (5′-AGC UAC AUC UGG CUA CUG GGU CUC-3′) specific to the 3′UTR region of c DNMT3B from miRDB, a microRNA target prediction and functional annotation database [17]. [score:9]
Expression patterns of miRNA and Regulation of cDNMT3B Expression patterns of miRNAs gga-miR-15c, gga-miR-29b, gga-miR-383 and gga-miR-222 were examined during meiotic stages of germ line development by qRT-PCR. [score:7]
Correlation between c DNMT3B and miRNAs expressions during meiotic stages of germ line development suggests that gga-miR-15c, gga-miR-383 and gga-miR-222 may downregulate c DNMT3B in vivo in both male and female chickens. [score:7]
To examine the regulation of c DNMT3B expression, we selected four miRNAs including gga-miR-15c (5′-UAG CAG CAC AUC AUG GUU UGU A-3′), gga-miR-29b (5′-UAG CAC CAU UUG AAA UCA GUG UU-3′), gga-miR-383 (5′-AGA UCA GAA GGU GAU UGU GGC U-3′), and gga-miR-222 (5′-AGC UAC AUC UGG CUA CUG GGU CUC-3′) specific to the 3′UTR region of c DNMT3B from miRDB, a microRNA target prediction and functional annotation database [17]. [score:6]
In correlation with c DNMT3B expression, gga-miR-15c, gga-miR-383 and gga-miR-222 expressions were increased after E11.5 in males. [score:5]
miR-383 expression was detected at a moderate level on E9.5, after this period, the expression was decreased to a low level in all stages (Fig. 10). [score:5]
Regulation of c DNMT3B using the c DNMT3B 3′UTR target miRNAs gga-miR-15c, gga-miR-29b, gga-miR-383, and gga-miR-222 is of great interest in this study. [score:4]
Our studies in chickens reinforce that miR-15c, miR-29b, miR-383 and miR-222 may downregulate DNMT3B in PGCs from female embryos after they enter meiosis. [score:4]
Expression patterns of miRNAs gga-miR-15c, gga-miR-29b, gga-miR-383 and gga-miR-222 were examined during meiotic stages of germ line development by qRT-PCR. [score:4]
We performed miRNA to examine the relative quantification of the expression level of gga-miR-15c, gga-miR-29b, gga-miR-383 and gga-miR-222 during germ line development. [score:4]
Earlier publications reported the downregulation of DNMT3B by miR-29b or miR-383 particularly in tumor cells [31], [32]. [score:4]
We examined the expression of gga-miR-15c, gga-miR-29b, gga-miR-383 and gga-miR-222 during meiotic stages of germ line development by qRT-PCR. [score:4]
We also suggest that miR-15c, miR-383 and miR-222 may downregulate DNMT3B in PGCs from male embryos. [score:4]
Expression of gga-miR-15c, gga-miR-29b, gga-miR-383 and gga-miR-222 during meiotic stages of germ line development examined by qRT-PCR. [score:4]
miR-383 significantly interacts with growth arrest and the DNA damage-inducible gamma (GADD45G) gene, which inhibits cell growth and induces apoptosis. [score:3]
Our dual fluorescent reporter assay suggests that gga-miR-29b, gga-miR-383 and gga-miR-222 may cause maximum (30.01–31.28%) downregulation of c DNMT3B in vitro. [score:3]
miR-383 expression is abundant in meiotic prophase cells and primary spermatocytes in mammals [30]. [score:3]
During male germ line development, miR-15c, miR-383 and miR-222 were detected at a low level on E9.5 to E11.5. [score:2]
c DNMT3B 3′UTR and cDNMT3B 3′UTR mutants for each miRNA binding sites generated by point mutation cloned into a pcDNA3 plasmid encoding eGFP and c DNMT3B 3′UTR-specific miRNAs including gga-miR-15c, gga-miR-29b, gga-miR-383, and gga-miR-222 cloned into a pDsRed2-N1 plasmid, respectively, encoding RFP were cotransfected into 293 FT cells. [score:2]
Compared to each mutants, c DNMT3B 3′UTR eGFP expression was slightly decreased by gga-miR-15c (25.82%), gga-miR-29b (30.01%), gga-miR-383 (30.0%), and gga-miR-222 (31.28%). [score:2]
miR-15c, miR-29b, miR-383 and miR-222 binding sites in chicken and corresponding human and mouse sequences are shown in red colour. [score:1]
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2
[+] score: 3
Most of the changed microRNAs are involved in development (especially in the embryonic development) and some examples of them are miRNA-222, miRNA-383, miRNA-126, miRNA-133, miRNA-30, miRNA-10a, miRNA-196 and miRNA-18b. [score:3]
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3
[+] score: 3
CISH is a target of miR-21, miR-383 and miR-205a. [score:3]
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4
[+] score: 2
Other miRNAs from this paper: gga-mir-19a, gga-mir-18a, gga-mir-200b, gga-mir-23b
Previous studies have demonstrated that miR-383 24 and miR-23a 25 are regulatory factors for IRF1. [score:2]
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5
[+] score: 1
The other seven miRNAs (miR-460B-5P, miR-383-5p, miR-181b-5p, gga-let-7b, miR-301b-3p, miR-10a-3p and miR-217-5p) created the other half of the network, interacting with 13 other protein-coding genes that are related to the immune system, hemarthrosis, arteriosclerosis obliterans, apoptosis, survival caspase cascade and muscular dystrophy. [score:1]
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