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9 publications mentioning gga-mir-451

Open access articles that are associated with the species Gallus gallus and mention the gene name mir-451. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 24
Comparing the inhibition of luciferase activity by the lentiviral expressed and endogenously expressed miRNAs, these results show that 1) the lentiviral expressed miR126 (both sense and antisense strands) and miR140 antisense strand exhibit potent RNAi activity; 2) the lentiviral expressed miR451 antisense strand does not have any RNAi activity; 3) the observed RNAi activity of lentiviral expressed miR21 (both sense and antisense strands) and miR140 sense strand could be due to endogenous miRNAs. [score:13]
Expression of the sense but not the antisense strand of gga-miR451 inhibited Renilla luciferase activity, consistent with the report from miRBase [23]. [score:5]
Based on literature reports and the miRNA database (miRBase), we chose four endogenous chicken miRNAs gga-miR21, gga-miR126, gga-miR140 and gga-miR451 that are expressed in many different tissues of adult chicken and chicken embryo [22]. [score:3]
Because gga-miR21, gga-miR126, gga-miR140 and gga-miR451 are generally expressed, we assayed their activity in DF-1 cells by directly transfecting the reporter plasmids into DF-1 cells. [score:3]
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[+] score: 14
In 7-week-old chickens, as compared with 14-day-old embryos, the expression of let-7b, miR-30a-5p, miR-30b, miR-99a and miR-133b was significantly up-regulated, but miR-16c, miR-92, miR-106, miR-203, miR-451 and miR-454 were significantly down-regulated in both dwarf and normal chickens. [score:8]
The expression of miR-16c, miR-92, miR-106, miR-203, miR-451, and miR-454 was commonly down-regulated (Table  2). [score:6]
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[+] score: 10
Specifically, there was a 2.05 fold up-regulation (7.25 fold in deep sequencing analysis) in miR-451, and 4.71 fold down regulation (2.86 fold in deep sequencing analysis) in miR-206 with AIV infection in lungs (P < 0.05). [score:5]
The expression levels of miR-206 and miR-451 in each sample were measured in terms of threshold cycle value and normalized to U6 expression using 2 [-∆∆CT][48]. [score:3]
There was general consistency between the TaqMan assays and deep sequence analysis of miR-451 and miR-206 in terms of direction of regulation and statistical significance (Figure 3). [score:2]
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[+] score: 10
gga-miR-451 was too down-regulated by GH in chicken hepatocytes in our study, indicating gga-miR-451 might mediate GH regulation of chicken liver metabolism but gga-miR-29b played different roles in GH regulation of liver metabolism comparing to miR-29b in rat. [score:6]
In male rat livers, miR-451 and miR-29b are down-regulated by GH [45]. [score:4]
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[+] score: 7
Their study showed that several host-encoded miRNAs, including gga-miR-155, gga-miR-150, gga-miR-451, gga-miR-26a, and gga-miR-223, were down-regulated in all MDV-transformed cell lines compared to normal splenocytes, and nine MDV-1-encoded miRNAs were up-regulated in all of the MDV-transformed cell lines compared to the MDV -negative reticuloendotheliosis virus (REV)-T-transformed cell line AVOL-1. Previous studies have mainly focused on miRNA profiles of MDV-infected CEF and MDV-transformed cell lines and expression of several individual miRNAs in MDV -induced splenic tumors. [score:7]
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[+] score: 6
Other miRNAs from this paper: gga-mir-26a, gga-mir-223, gga-mir-146a, gga-mir-126
Comparative miRNA expression profiles of 7 MDV-transformed T-cell lines showed that host-encoded miRNAs such as miR-26a, miR-223, miR-150, miR-451 and miR-126 were consistently downregulated [3]. [score:6]
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[+] score: 5
Last but not least, expression levels of 10 miRNAs can be perturbed in animals when fed with high-fat diet (miR-142–5p and miR-101) [74– 78], or with obesity or obesity-related diseases (miR-10a, miR-218, miR-429, miR-200a, miR-200b, miR-451, miR-142–3p, and miR-454) [77, 79– 85], which indicates that they could be potentially related to adipogenesis. [score:5]
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[+] score: 4
The host miRNAs downregulated in the MDV-transformed cell lines include miR-155, miR-223, miR-150, miR-451, and miR-26a. [score:4]
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[+] score: 3
Avian influenza impacted the expression levels of several miRNAs in the chicken trachea and lung including the following miRNAs significant in the current study: let-7a-1, let-7f, let-7j, mir-1b, mir-30d, mir-34c, mir-101-2, mir-144, mir-200b, and mir-451 (Wang et al., 2009). [score:3]
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