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7 publications mentioning gga-mir-460a

Open access articles that are associated with the species Gallus gallus and mention the gene name mir-460a. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 23
Other miRNAs from this paper: hsa-let-7d, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-17, hsa-mir-21, hsa-mir-22, hsa-mir-30a, hsa-mir-32, hsa-mir-33a, hsa-mir-148a, hsa-mir-30c-2, hsa-mir-30d, hsa-mir-147a, hsa-mir-34a, hsa-mir-187, hsa-mir-204, hsa-mir-205, hsa-mir-200b, hsa-mir-23b, hsa-mir-30b, hsa-mir-125b-1, hsa-mir-138-2, hsa-mir-142, hsa-mir-144, hsa-mir-125b-2, hsa-mir-138-1, hsa-mir-146a, hsa-mir-190a, hsa-mir-200c, hsa-mir-155, hsa-mir-30c-1, hsa-mir-200a, hsa-mir-30e, hsa-mir-365b, hsa-mir-328, gga-mir-33-1, gga-mir-125b-2, gga-mir-155, gga-mir-17, gga-mir-148a, gga-mir-138-1, gga-mir-187, gga-mir-32, gga-mir-30d, gga-mir-30b, gga-mir-30a, gga-mir-30c-2, gga-mir-190a, gga-mir-204-2, gga-mir-138-2, gga-let-7d, gga-let-7f, gga-mir-146a, gga-mir-205b, gga-mir-200a, gga-mir-200b, gga-mir-34a, gga-mir-30e, gga-mir-30c-1, gga-mir-205a, gga-mir-204-1, gga-mir-23b, gga-mir-142, hsa-mir-449a, hsa-mir-489, hsa-mir-146b, hsa-mir-548a-1, hsa-mir-548a-2, hsa-mir-548a-3, hsa-mir-33b, hsa-mir-449b, gga-mir-146b, gga-mir-147, gga-mir-489, gga-mir-449a, hsa-mir-449c, gga-mir-21, gga-mir-144, hsa-mir-147b, hsa-mir-190b, gga-mir-22, gga-mir-460b, gga-mir-1662, gga-mir-1684a, gga-mir-449c, gga-mir-146c, gga-mir-449b, gga-mir-2954, hsa-mir-548aa-1, hsa-mir-548aa-2, hsa-mir-548ab, hsa-mir-548ac, hsa-mir-548ad, hsa-mir-548ae-1, hsa-mir-548ae-2, hsa-mir-548ag-1, hsa-mir-548ag-2, hsa-mir-548ah, hsa-mir-548ai, hsa-mir-548aj-1, hsa-mir-548aj-2, hsa-mir-548ak, hsa-mir-548al, hsa-mir-548am, hsa-mir-548an, hsa-mir-548ao, hsa-mir-548ap, hsa-mir-548aq, hsa-mir-548ar, hsa-mir-548as, hsa-mir-548at, hsa-mir-548au, hsa-mir-548av, hsa-mir-548aw, hsa-mir-548ax, hsa-mir-548ay, hsa-mir-548az, gga-mir-365b, gga-mir-33-2, gga-mir-125b-1, gga-mir-190b, gga-mir-449d, gga-mir-205c
We noticed the miR-33-5p, miR-460a-5p, miR-365b-5p, miR-125b-5p and miR-2954 correlated with inflammatory genes including MEOX2, IL-1BETA, TRAF2, TNFRSF1B and MAP3K8, and except for the up-regulated miR-33-5 correlated with under expression of MEOX2, other down-regulated miRNAs all correlated with overexpression targets. [score:13]
Similarly, we found that down regulated miR-460a-5p also correlated with the overexpression target gene IRF8 in the AS broilers’ pulmonary artery tissues. [score:6]
In this study, we also found that the down-regulated miR-460a-5p and miR-125b-5p were relevant to STAT3 and STAT5 these two genes, respectively. [score:4]
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[+] score: 16
Therefore, although little is known about the specific functions of several of these miRNAs (e. g. miR-31, miR-101, miR-200b, miR-10b, miR-460, miR-15b, miR-16 and miR203) during muscle development, the close relationship between their targets and myogenesis regulation demonstrates a potential role during muscle development. [score:6]
Seven (miR-101, miR-10a, miR-10b, miR-1677, let-7f, miR-31, and miR-205b) were expressed at higher levels in layers, and ten (miR-203, miR-200b, miR-16c, miR-15b, miR-15c, miR-460, miR-429, let-7c, miR-2188, and gga-miR-N2) were expressed at higher levels in broilers. [score:5]
However, the majority including one novel miRNAs (gga-miR-N2) and eight known miRNAs (miR-101, miR-15b, miR-15c, miR-1677, miR-200, miR-460, gga-mir-2188 and miR-429) have not been implicated in the regulation of muscle development. [score:3]
Little is known about the functional roles of the remaining eight (miR-31, miR-101, miR-200b, miR-10b, miR-460, miR-15b, miR-16 and miR-203) during muscle development. [score:2]
[1 to 20 of 4 sentences]
[+] score: 14
Non-infected (Fold-change) miRNA [1] (fold change)MX1 myxovirus (influenza virus) resistance 1 [27]Z23168+11.46gga-miR-155(+3.55)gga-miR-206(−2.86)Interleukin 8 (IL8) [28]M16199+11.03gga-miR-32(+7.98)Interferon regulatory factor 7 (IRF7) [29]U20338+2.11gga-miR-142-5p(+2.84)Interleukin1receptor-like1, transcript variant1 [51]AB041738+1.65gga-miR-460 (only expressed in infected lungs)TNF receptor superfamily, member 19 [30]BX931334−1.85gga-miR-187(−4.35)Tipartite motif-containing 7.1 [52]BX934475−1.81NA [2]RAC serine/threonine-protein kinase3 (ATK3) [53]BX950472−1.65NAC-fringe 1 [54] U97157 −1.52 NANote: [1]miRNAs targeting on differentially expressed immune related genes; [2] No miRNAs targeting on the gene; +: Up-regulated with AIV infection; –: Down- regulated with AIV infection. [score:14]
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[+] score: 14
In the E11_VS_E16 group, miR-6561-5p, miR-203a, miR-3536 and miR-460a-5p were predicted to regulate their cognate target genes. [score:4]
In this group, miR-6561-5p, miR-203a, miR-3536 and miR-460a-5p potentially targeted 12, 10, 9 and 8 mRNAs, respectively. [score:3]
Networking interactions showed that miR-460a-5p targeted the eight mRNAs ACTN2, CAP2, SGCD, RTN4, PIKA, COL15A1, FXR1 and CLASP2. [score:3]
Furthermore, in the E11_VS_E16 contrast group, 8 miRNAs (miR-203a, miR-6561-5p, miR-460a-5p, miR-205a, miR-3536, miR-103-3p miR-205b, and miR-200b-3p) were highly regulated. [score:2]
Moreover, in the E11_VS_P1 contrast group, eleven miRNAs (miR-6548-5p, miR-19a-5p, miR-3536, miR-6631-5p, miR-222a, miR-140-3p, miR-92-5p, miR-135a-5p, miR-455-3p, miR-460a-5p and miR-200a-3p), were highly regulated. [score:2]
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[+] score: 8
However, among the remaining 12 miRNAs, we found that miR-2188 affects embryonic development in fishes [86, 87]; miR-1306 is related to Alzheimer’s disease by targeting ADAM10 [88]; miR-1684 was differentially expressed in chicken lines selected for necrotic enteritis [89]; miR-1b could be potentially related to immunity genes in insects [90]; no literature was found for the other 8 miRNAs (miR-3535, miR-1434, miR-1805–3p, miR-1551, miR-1563, miR-1653, miR-1416, miR-460a). [score:8]
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[+] score: 3
Expression patterns of 15 miRNAs identified using RT-PCR agreed with those identified using deep sequencing, miR-101, miR-10a, miR-10b, miR-1677, let-7f, and miR-31 were higher in layers, while miR-200b, let-7c, miR-16c, miR15b, miR-15c, miR460, miR-429, miR-2188, and the novel miR-N2 were higher in broilers. [score:3]
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[+] score: 1
These microRNAs show no sequence similarity to any known microRNAs, with the exception of #46, which is similar, but not identical to dre-miR-730 (21/22) and gga-miR-460 (19/22). [score:1]
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