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5 publications mentioning ame-mir-14

Open access articles that are associated with the species Apis mellifera and mention the gene name mir-14. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 18
Interestingly, the EcR mRNA has predicted binding sites for miR-14 (data not shown), and our global gene expression assays revealed a downregulation of this miRNA in bees silenced for EcR gene function. [score:5]
These results suggest that in A. mellifera, EcR gene expression is regulated in a loop-type mechanism involving miR-14, as already demonstrated for D. melanogaster (Varghese and Cohen, 2007; for a comprehensive review see Yamanaka et al., 2013). [score:4]
Moreover, ecdysteroid signaling was shown to be linked to the expression levels of the let-7-C cluster genes, as well as of miR-14 and miR-34 during insect development (for review see Kucherenko and Shcherbata, 2013). [score:4]
Many of the miRNAs affected by EcR knockdown in honeybees (let-7, miR-1, miR-9a, miR-12, miR-14, miR-34, miR-79, miR-92b, miR-124, miR-184, miR-210, miR-219, miR-263a, miR-276, miR-279, miR-283, miR-305, miR-306, miR-316, miR-317) have previously been reported as putatively involved in the regulation of D. melanogaster immune genes, particularly those belonging to the JNK, Imd and Toll signaling pathways (Fullaondo and Lee, 2012). [score:3]
microRNA miR-14 acts to modulate a positive autoregulatory loop controlling steroid hormone signaling in Drosophila. [score:2]
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[+] score: 5
In the network constructed with miRNAs, mRNAs and lncRNAs, we found that some genes served as bridges linking different miRNAs, four of which (gene id: 408284, 408609, 409587, and 409152) acting as miRNA targets linked let-7, miR-100, miR-12, miR-14, miR-316 and miR-996. [score:3]
Additionally, miR-14 and miR-8 have been suggested to be associated with juvenile hormones (JH) and ecdysteroids (Ec), which play key roles in ovary development and other reproductive behaviors in honey bees (Boecking, Bienefeld & Drescher, 2000; Flatt, Tu & Tatar, 2005; Goodman & Cusson, 2012; Hartfelder & Emlen, 2005; Hoover et al., 2003; Riddiford, 1994; Wyatt & Davey, 1996). [score:2]
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[+] score: 5
EcR expression and activity levels have been shown to be negatively regulated by mir-14 55. [score:4]
Consistent with this role, ame-mir-14 levels were elevated in queens relative to workers. [score:1]
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[+] score: 4
In the up-regulated miRNAs (Table S1), ame-bantam, ame-mir-184, ame-mir-14, ame-mir-252 were the most abundant in RJM. [score:4]
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[+] score: 3
In Drosophila, mir-14 deficiency is associated with a variety of phenotypes, including a lower probability of larvae to survive development to adulthood, reduced adult lifespan, stress-sensitivity and abnormal energy metabolism [24], [25]. [score:2]
One of these genes is mir-14, which has diminished levels in the IE data set (−0.52 log [2]-fold change) (Table 1). [score:1]
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