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2 publications mentioning dme-mir-958

Open access articles that are associated with the species Drosophila melanogaster and mention the gene name mir-958. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 20
Using bioinformatics to identify putative target mRNAs combined with functional annotation cluster analysis, we find that targets of miRs-8 and -289 (but not miR-958) are enriched in neuron-related clusters (Figure 5B–D). [score:5]
When the lar reporter was co -transfected with each activity-regulated miRNA, we found that all three significantly repressed luciferase expression (Figure 6A; miR-8 = 24%; miR-289 = 39%; miR-958 = 32%; all at p<0.0001). [score:4]
Using miRecords, we identified 490 putative mRNA targets for miR-8, 2494 for miR-289, and 304 for miR-958 (Figure 5A; Table S3). [score:3]
Note that the 304 predicted targets for miR-958 were not enriched in these clusters. [score:3]
Interestingly, we found that predicted targets for miRs-8 and -289 but not miR-958 were found in these enriched annotation clusters (Figure 5B–C; Table S3; enrichment scores = 6.1 and 15.9 respectively). [score:3]
miR-8, miR-289, and miR-958 Negatively Regulate Activity -dependent Growth. [score:2]
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[+] score: 4
Of these, 5 miRNAs (miR-987–5p, miR-277–3p, miR-958–3p, miR-956–3p, miR-252–5p) were upregulated ≥4-fold in Dis3 -depleted discs. [score:4]
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