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miRBase |
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![]() 5 publications mentioning rno-mir-488Open access articles that are associated with the species Rattus norvegicus and mention the gene name mir-488. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary. |
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Other miRNAs from this paper: rno-mir-140, rno-mir-135b, rno-let-7f-1, rno-let-7f-2, rno-mir-21, rno-mir-31a, rno-mir-34a, rno-mir-128-1, rno-mir-128-2, rno-mir-135a, rno-mir-141, rno-mir-143, rno-mir-145, rno-mir-153, rno-mir-200c, rno-mir-200b, rno-mir-298, rno-mir-455, rno-mir-490, rno-mir-875, rno-mir-711, rno-mir-31b
MiR-21, miR-31 and miR-488 are down-regulated, while miR-153, miR-135b, miR-135a and miR-298 are up-regulated in secretory-stage enamel formation compared to maturation-stage.
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The expression patterns of seven selected miRNAs (miR-21, miR-31, miR-488, miR-153, miR-135b, miR-135a and miR-298) were examined (Figure 6E-R).
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Seven differentially expressed miRNAs (miR-21, miR-31, miR-488, miR-153, miR-135b, miR-135a and miR298) in secretory- and/or maturation-stage enamel organs were confirmed by in situ hybridization.
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In situ hybridization analyses of miR-21, miR-31 and miR-488 generated higher signal intensities in maturation-stage enamel organ cells than in secretory-stage enamel organ cells (Figures 6E and 4J), and this data correlates well (same directional change) with the miRNA qPCR array data/fold increase (i. e., miR-21, miR-31, miR-488 increased by 5.2, 9.5 and 6.9 fold, respectively) (Additional file 1).
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Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7d, hsa-mir-22, hsa-mir-27a, hsa-mir-92a-1, hsa-mir-92a-2, hsa-mir-29b-1, hsa-mir-29b-2, hsa-mir-129-1, hsa-mir-148a, hsa-mir-210, hsa-let-7g, hsa-let-7i, hsa-mir-138-2, hsa-mir-145, hsa-mir-125b-2, hsa-mir-126, hsa-mir-129-2, rno-let-7d, rno-mir-129-2, rno-let-7a-1, rno-let-7a-2, rno-let-7i, rno-mir-22, rno-mir-27a, rno-mir-29b-2, rno-mir-29b-1, rno-mir-92a-1, rno-mir-92a-2, rno-mir-125b-2, rno-mir-126a, rno-mir-129-1, rno-mir-138-2, rno-mir-145, rno-mir-210, hsa-mir-488, hsa-mir-920, rno-mir-126b, rno-let-7g, rno-mir-148a, rno-mir-29b-3
miR-488, suppresses the expression of panic disorder gene pro-opiomelanocortin.
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Overexpression of miR-488 dysregulated corticotropin releasing hormone signalling, which is a crucial pathway activated in response to stress [25].
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Muiños-Gimeno M. Espinosa-Parrilla Y. Guidi M. Kagerbauer B. Sipilä T. Maron E. Pettai K. Kananen L. Navinés R. Martín-Santos R. Human microRNAs miR-22, miR-138-2, miR-148a, and miR-488 are associated with panic disorder and regulate several anxiety candidate genes and related pathwaysBiol.
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miR-125b-2* and miR-488 peaked at 6 h from the onset of stroke, to 1.56 ± 0.28 and 1.36 ± 0.24 fold, respectively in ischemic rat brain whereas miR-27a*, -422a and -627 peaked at 24 h from the onset of stroke, to 5.37 ± 0.46, 1.52 ± 0.28 and 8.53 ± 1.23 fold, respectively (Figure 4).
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In fact, a recent study reported a cause-effect association between micro -RNA488 (or miR488) and ZIP8 in osteoarthritis by involving in a reduced degradation of chondrocytes [37].
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We have not confirmed this epigenetic effect of IH via assessing amount of miR488 in our mo del yet.
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Roles of zinc uptake transporters such as ZIP8 in bone and miR488 may be crucial since a low bone mineral density is a typical symptom of T1D and T2D [38].
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Other miRNAs from this paper: rno-mir-181c, rno-mir-181a-2, rno-mir-181b-1, rno-mir-181b-2, rno-mir-181a-1, rno-mir-383, rno-mir-377, rno-mir-485, rno-mir-181d, rno-mir-384
org) revealed several miRNA that might interact with POMC mRNA untranslated region, including miR-488, miR-485, miR-384-3p, miR-383, miR-377, miR-485-5p and miR-181 (family).
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Other miRNAs from this paper: rno-mir-7a-1, rno-mir-7a-2, rno-mir-7b, rno-mir-29b-2, rno-mir-29b-1, rno-mir-34b, rno-mir-34c, rno-mir-34a, rno-mir-129-1, rno-mir-130b, rno-mir-181a-2, rno-mir-181a-1, rno-mir-383, rno-mir-484, rno-mir-29b-3
We were unable to detect reproducible changes in the levels of miR-29b, miR-129-1* (currently annotated miR-129-1-3p), miR-484 and miR-488 (ESM Fig. 3).
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