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26 publications mentioning hsa-mir-1285-1

Open access articles that are associated with the species Homo sapiens and mention the gene name mir-1285-1. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 65
In a transcriptome analysis of similar phenotypic comparison groups in Ethiopians with scarring trachoma [2], 25% of predicted targets of miR-1285 and 52% of predicted targets of miR-147b predicted targets (TargetScan v6.2) were differentially regulated (adjusted p<0.05). [score:10]
This is consistent with the array results in which miR-147b was up-regulated 9.6 fold in individuals with TSI versus N. MiR-1285 was up-regulated 4.6 fold in TSI relative to TS (p = 0.005). [score:7]
miR-147b is significantly up-regulated in TSI versus N (fold change = 2.3, p = 0.03) and miR-1285 is up-regulated in TSI versus TS (fold change = 4.6, p = 0.005), which was consistent with the results of the qPCR array. [score:7]
MiR-147b was up-regulated in individuals with TSI compared to N and miR-1285 was up-regulated in people with TSI compared to those with TS alone. [score:5]
In order to understand the mechanisms by which these miR may contribute to health and disease of the conjunctiva the associations of miR-147b and miR-1285 with trachomatous disease now requires further study. [score:5]
This is also consistent with the array results in which miR-1285 was up-regulated 16 fold in TSI versus TS. [score:4]
miR-147b and miR-1285 are up-regulated in inflammatory trachomatous scarring. [score:4]
Expression levels of miR-1285 were reduced in clinical samples of renal cell carcinoma (RCC) compared to healthy mucosa and miR-1285 transfection in RCC cell lines in vitro led to inhibition of cell proliferation, migration and invasion [20]. [score:4]
The authors verified transglutaminase 2 (TGM2) as a target of miR-1285. [score:3]
In contrast, Hidaka and colleagues [20] find miR-1285 to be a tumor suppressor. [score:3]
We confirmed that miR-147b and miR-1285 have increased expression in individuals with trachomatous scarring in the presence of clinically significant inflammation. [score:3]
Two miR with significantly increased expression in trachomatous scarring and inflammation were identified (miR-147b and miR-1285). [score:3]
MiR-1285 directly targets the 3′UTR of p53 mRNA in HEK 293T cells [19]. [score:3]
Seven miR were selected for follow-up (supplementary table S7) including three miR that were differentially regulated in the N v TS comparison (miR-30c, miR-32, miR-203) and four from the N v TSI comparison (miR-10a, miR-147b, miR-1285, miR-1305). [score:2]
In vitro studies in primary conjunctival epithelia will be required to understand the function of miR-1285 in chlamydial infection and trachoma. [score:1]
Only miR-1285 and miR-147b showed a significant difference between the different phenotypic groups in this validation set (table 5). [score:1]
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[+] score: 47
Based on the fold changes, qRT-PCR was performed to validate microarray results on 12 miRNAs, specifically miRNAs up-regulated in both heart and plasma (miR-660-3p, miR-665, miR-1285-3p and miR-4491), down-regulated in heart but up-regulated in plasma (miR-206 and miR-1268b), up-regulated in heart but down-regulated in plasma (miR-130-3p, miR-199a and miR-330-3p), down-regulated in both heart and plasma (miR-221-30, miR-487b-3p and miR-4288), were chosen for validation test in the plasma of 45 control and 45 CHF patients. [score:19]
Analysis of miRNAs expression revealed that miR-660-3p, miR-665, miR-1285-3p, miR-4491 and miR-130a-3p were relatively cardiac-enriched, while the remaining miRNAs showed a non-cardiac highly expression patterns (Supplemental Figure 1). [score:5]
Among the 10 successfully validated miRNAs, only 4 cardiac fibroblast-derived miRNAs (miR-660-3p, miR-665, miR-1285-3p and miR-4491) were upregulated both in heart and circulation. [score:4]
Then, we identified 3 cardiac fibroblast-derived circulating miRNAs (miR-660-3p, miR-665 and miR-1285-3p) significantly upregulated in CHF (in heart and circulation) and correlated to CHF severity, holding promises as diagnostic biomarker for CHF. [score:4]
Four cardiac fibroblast-derived miRNAs (miR-660-3p, miR-665, miR-1285-3p and miR-4491) were found significantly upregulated in heart and plasma during heart failure. [score:4]
In this study, 4 cardiac fibroblast-derived circulating miRNAs (miR-660-3p, miR-665, miR-1285-3p and miR-4491) performed better than other miRNAs in distinguishing CHF and indicating disease severity. [score:3]
However, recent studies demonstrates that miR-21-3p, which has a similar limited abundance to miR-665, miR-1285-3p and miR-4491 (Supplemental Figure 4), plays important role in cardiac hypertrophy, suggesting that miRNA with limited abundance may play important roles in diseases and should not be left ignore [24, 25]. [score:3]
Interestingly, as shown in Figure 4, we found significant correlations with LVEF% (P < 0.05) for 3 cardiac fibroblast-derived circulating miRNAs, namely miR-660-3p, miR-665 and miR-1285-3p, while the other miRNAs showed no significant correlation. [score:1]
Further bioinformatics analysis aids us in the interpretation of the biological functions of these cardiac-related miRNAs (miR-660-3p, miR-665, miR-1285-3p and miR-4491) in CHF. [score:1]
However, most miRNAs provided here have not been well studied before (including miR-660-3p, miR-665, miR-1285-3p and miR-4491), probably due to the following reasons. [score:1]
The results showed that 4 cardiac fibroblast derived circulating miRNAs (miR-660-3p, miR-665, miR-1285-3p and miR-4491) all exhibited high accuracy for diagnosis (> 0.9). [score:1]
As a result, 8 of the 12 selected miRNAs (miR-660-3p, miR-665, miR-1285-3p, miR-4491, miR-206, miR-1268b, miR-130-3p and miR-330-3p) were successfully validated in the second cohort. [score:1]
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[+] score: 21
Other miRNAs from this paper: hsa-mir-25, hsa-mir-30d, hsa-mir-210, hsa-mir-1285-2
Tian S. Huang S. Wu S. Guo W. Li J. He X. MicroRNA-1285 inhibits the expression of p53 by directly targeting its 3’ untranslated region Biochem. [score:9]
In addition, we recently discovered that p53 was targeted by miR-1285, miR-25 and miR-30d through analysis using both bioinformatics tools (miRGen, TargetScan, Pictar, and Miranda) and the most current literature [25, 26, 27]. [score:5]
As shown in Figure 5a, qPCR analysis revealed a significant MeHg -induced downregulation of the three miRNAs in ihNPCs (miR-30d fold change: 10 nM, 0.25 ± 0.02; 50 nM, 0.58 ± 0.04; miR-1285 fold change: 10 nM, 0.87 ± 0.11; 50 nM, 0.13 ± 0.01; miR-25 fold change: 10 nM, 0.68 ± 0.03; 50 nM, 0.78 ± 0.07). [score:4]
Therefore, we examined the changes in these miRNAs (miR-30d, miR-1285, miR-25), which may have a potential impact on p53 expression. [score:3]
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[+] score: 15
We have previously found that miR-147b and miR-1285 are up-regulated in adult cases of scarring and inflammatory trachoma [15]. [score:4]
Two miR that were previously found to be up-regulated in inflammatory trachomatous scarring (miR-147b and miR-1285) [15] were also tested by qPCR in these samples. [score:4]
We previously showed that microRNAs (miR) -147b and miR-1285 were up-regulated in inflammatory trachomatous scarring. [score:4]
We did not find miR-147b or miR-1285 to be differentially expressed in Ct positive or Ct negative follicular trachoma cases. [score:3]
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[+] score: 13
Tian S. Huang S. Wu S. Guo W. Li J. He X. MicroRNA-1285 inhibits the expression of p53 by directly targeting its 3’ untranslated region Biochem. [score:9]
Similarly, other microRNAs such as miR-125b, miR-125a and miR-1285 have been described as negative regulator of TP53 [104, 105, 106]. [score:2]
Interestingly, miR-612, which has the same seed sequence as miR-1285, cannot bind to the 3′-UTR of TP53, highlighting the tight regulation of p53 by miRNAs [106]. [score:2]
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[+] score: 13
Of note, miR-1285, which negatively regulates the expression of the crucial tumor suppressor p53 [14], was upregulated approximately 3-fold (p = 0.02, unadjusted). [score:9]
The expression levels of a number of microRNAs known to be involved in the regulation of cellular processes like apoptosis, proliferation, invasion, local immune response and radioresistance (e. g. miR-1285, miR-24-1, miR-151-5p, let-7i) displayed 2 - 3-fold changes after irradiation. [score:4]
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[+] score: 12
LCN2 has target sites for miR-34a and miR-1285, which are both upregulated in the liver. [score:6]
MiR-215-5p (FC 3.1; p value 0.02) and miR-1285 (FC 2.9; p value 7.35x10 [-5]) were the most upregulated miRNAs. [score:4]
MiR-1285 and miR-199a-5p were also up regulated with fold changes of > 1.5 and p values < 0.05. [score:2]
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[+] score: 12
To further validate the miRNA microarray results, 5 out of the most obvious up-regulated miRNAs (miR-6723-5p, miR-1285-3p, miR-619-5p, miR-1290 and miR-1273a) and 5 out of the most obvious down-regulated miRNAs (miR-98, miR-7846-3p, miR-668-5p, miR-4738-3p and miR-4654) were selected to determine their relative expression levels on hypertrophic scar tissues to verify the effect of chips. [score:9]
showed that relative expression values of miR-6723-5p, miR-1285-3p, miR-619-5p, miR-1290 and miR-1273a were above 0 and that relative levels of miR-98, miR-7846-3p, miR-668-5p, miR-4738-3p and miR-4654 were below 0 (Fig.   1b). [score:3]
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[+] score: 9
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7e, hsa-mir-17, hsa-mir-18a, hsa-mir-19a, hsa-mir-20a, hsa-mir-21, hsa-mir-92a-1, hsa-mir-92a-2, hsa-mir-93, hsa-mir-101-1, hsa-mir-106a, hsa-mir-107, hsa-mir-192, hsa-mir-34a, hsa-mir-204, hsa-mir-205, hsa-mir-214, hsa-mir-215, hsa-mir-222, hsa-mir-223, hsa-mir-1-2, hsa-mir-15b, hsa-mir-125b-1, hsa-mir-141, hsa-mir-191, hsa-mir-125a, hsa-mir-125b-2, hsa-mir-126, hsa-mir-127, hsa-mir-149, hsa-mir-184, hsa-mir-186, hsa-mir-200c, hsa-mir-1-1, hsa-mir-200a, hsa-mir-101-2, hsa-mir-34b, hsa-mir-34c, hsa-mir-339, hsa-mir-146b, hsa-mir-548a-1, hsa-mir-548b, hsa-mir-548a-2, hsa-mir-548a-3, hsa-mir-548c, hsa-mir-624, hsa-mir-650, hsa-mir-651, hsa-mir-548d-1, hsa-mir-548d-2, hsa-mir-449b, hsa-mir-1185-2, hsa-mir-1283-1, hsa-mir-1185-1, hsa-mir-708, hsa-mir-548e, hsa-mir-548j, hsa-mir-1285-2, hsa-mir-548k, hsa-mir-548l, hsa-mir-548f-1, hsa-mir-548f-2, hsa-mir-548f-3, hsa-mir-548f-4, hsa-mir-548f-5, hsa-mir-548g, hsa-mir-548n, hsa-mir-548m, hsa-mir-548o, hsa-mir-548h-1, hsa-mir-548h-2, hsa-mir-548h-3, hsa-mir-548h-4, hsa-mir-548p, hsa-mir-548i-1, hsa-mir-548i-2, hsa-mir-548i-3, hsa-mir-548i-4, hsa-mir-1283-2, hsa-mir-548q, hsa-mir-548s, hsa-mir-548t, hsa-mir-548u, hsa-mir-548v, hsa-mir-548w, hsa-mir-548x, hsa-mir-548y, hsa-mir-548z, hsa-mir-548aa-1, hsa-mir-548aa-2, hsa-mir-548o-2, hsa-mir-548h-5, hsa-mir-548ab, hsa-mir-548ac, hsa-mir-548ad, hsa-mir-548ae-1, hsa-mir-548ae-2, hsa-mir-548ag-1, hsa-mir-548ag-2, hsa-mir-548ah, hsa-mir-548ai, hsa-mir-548aj-1, hsa-mir-548aj-2, hsa-mir-548x-2, hsa-mir-548ak, hsa-mir-548al, hsa-mir-548am, hsa-mir-548an, hsa-mir-548ao, hsa-mir-548ap, hsa-mir-548aq, hsa-mir-548ar, hsa-mir-548as, hsa-mir-548at, hsa-mir-548au, hsa-mir-548av, hsa-mir-548aw, hsa-mir-548ax, hsa-mir-548ay, hsa-mir-548az, hsa-mir-548ba, hsa-mir-548bb, hsa-mir-548bc
Tumor associated miRNAs present in this network included miR-18a, miR-93, miR-146b, miR-200c, miR-214, miR-223, miR-650 and miR-1285, collectively repressing 9 tumor suppressors genes (including ARID2, ATM, CYLD, KLF6, NBN, SDHD, SMAD4, SMARCA4, TNFAIP3), nine oncogenes (including BCL2, CREB1, CREBBP, FOXO1, MYC, MYH11, MYH9, NOTCH1), growth inhibitors (BMPR2, BTG2, BTG3, LITAF and PA2G4), chromatin remo delers, six claudin genes (CLDN11, CLDN14, CLDN5, CLDN7, CLDN8, CLDND1) 11 DNA-repair/ATM pathway genes (ATF4, CREB3, CREB5, DCLRE1C, ERCC1, PARP1, POLR2C, RAD23B, RAD51, RPA1, XRCC5) and six proapoptotic genes (BAK1, BCL2L1, MCL1, SMAD3, SMAD5, SMAD7). [score:5]
miR-1285, which is a direct repressor of TP53 was overexpressed [30]. [score:4]
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[+] score: 8
Tumor suppressive microRNA-1285 regulates novel molecular targets: aberrant expression and functional significance in renal cell carcinoma. [score:8]
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[+] score: 7
More recently, we constructed a miRNA expression signature of RCC clinical specimens and successfully identified tumor suppressive miR-1285 targeting transglutaminase 2 (TGM2) (12). [score:7]
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[+] score: 6
On the other hand, although miR-211-3p, miR-1277-5p, miR-150-3p, miR-513b, miR-664b-5p, and hsa-miR-1285-3p were determined as downregulated in chronic brucellosis in the present study, the function of these miRNAs in infectious diseases remains unknown. [score:6]
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[+] score: 6
detected the expression profile of miRNAs from blood samples of influenza A H1N1 virus-infected patients and then exhibited that the expression levels of 193 miRNA molecules were altered in all influenza patients, of which 16 highly dysregulated miRNAs (miR-1260, miR-1285, miR-18a, miR-185*, miR-299-5p, miR-26a, miR-30a, miR-335*, miR-34b, miR-519e, miR-576-3p, miR-628-3p, miR-664, miR-665, miR-765 and miR-767-5p) were able to provide a clear distinction between infected and healthy individuals [39]. [score:6]
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[+] score: 5
hsa-miR-1285 and hsa-miR-541 had the largest number of genes (462 and 264 genes, respectively) targeted by the survival -associated miRs. [score:3]
07] 0.01 1p36.33 hsa-miR-126 −0.36 [−0.64 – −0.08] 0.01 9q34.3 hsa-miR-888 −0.56 [−1.02 – −0.10] 0.02 Xq27.3 hsa-miR-517b −0.22 [−0.41 – −0.03] 0.03 19q13.42 hsa-miR-363 −0.43 [−0.80 – −0.05] 0.03 Xq26.2 hsa-miR-216b −0.26 [−0.50 – −0.03] 0.03 2p16.1 hsa-miR-1285 −0.27 [−0.53 – −0.02] 0.04 7q21. [score:1]
For example, multivariate analysis improved the P value of the OV-miR pair hsa-miR-221 and hsa-miR-1285; hsa-miR-221 from 0.001 (Table 1) to 0.0003 (Table S2) and hsa-miR-1285 from 0.04 to 0.003. [score:1]
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[+] score: 4
Interestingly, many of the genes containing such highly differentiated SNPs in the Alu-miRNA sites within their 3′UTRs (listed in Table 1) have target sites (encompassing these SNPs) for miRNAs that are primate-specific (miR-661 29, miR-1202 53), human-specific (miR-4739, miR-5095) 54, involved in the regulation of p53 signaling (miR-660 55, miR-661 29, miR-1285 56) or in the apoptosis pathway (miR-17 44 45, miR-30b 57, miR-106a-3p 45, miR-612 58). [score:4]
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[+] score: 3
A total of twelve miRNAs were found to be commonly regulated over time in these three tissues; let-7d, let-7e, miR-1249, miR-1254, miR-1255, miR-1273, miR-1285, miR-1301, miR-1306, miR-548, and miR-8078. [score:2]
Binding sites of the miR-1273 family, miR-1285-3p and miR-5684 in human mRNAs. [score:1]
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[+] score: 3
However miR-1285, -18a, -185*, -30a, -34b, -665 and -765 showed opposing expression patterns (Table 2). [score:3]
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[+] score: 3
Furthermore, ectopic expression of miR-504, miR-33, and miR-1285 has been shown to induce phenotypic changes associated with the loss of p53, including reduced apoptosis and increased stemness [49]. [score:3]
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[+] score: 3
1. Pileup plots for small RNA reads mapping to miR-1285. [score:1]
While in 10 cases results matched well, for 2 miRNAs, however, the qRT-PCR data did not correspond to the NGS results (miR-26a-5p and miR-1285-5p). [score:1]
In contrast, for miR-1285, revealed a wired read mapping to the mature 5′ form on the precursor. [score:1]
[1 to 20 of 3 sentences]
[+] score: 1
Stringent editing criteria (recurrence in > 50 samples) identified 18 editing sites in 10 miRNAs (mir-24-2, mir-27a, mir-27b, mir-605, mir-641, mir-1254, mir-1285-1, mir-1304, mir-3126, and mir-3138; Table S5) and 2 snoRNAs (U88 and SNORD17). [score:1]
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[+] score: 1
Chen and co-workers identified a panel of 5miRNAin this regard; let-7c, let-7e, miR-30c, miR-622, and miR-1285. [score:1]
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[+] score: 1
For example, miR-1285 was observed in the present study might possibly lead to increased radioresistance in subsequent radiotherapy sessions. [score:1]
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[+] score: 1
Other miRNAs from this paper: hsa-mir-17, hsa-mir-28, hsa-mir-223, hsa-mir-127, hsa-mir-188, hsa-mir-194-1, hsa-mir-155, hsa-mir-194-2, hsa-mir-30e, hsa-mir-362, hsa-mir-363, hsa-mir-367, hsa-mir-379, hsa-mir-196b, hsa-mir-450a-1, hsa-mir-431, ssc-mir-28, hsa-mir-493, hsa-mir-512-1, hsa-mir-512-2, hsa-mir-500a, hsa-mir-501, hsa-mir-502, hsa-mir-450a-2, hsa-mir-513a-1, hsa-mir-513a-2, hsa-mir-506, hsa-mir-508, hsa-mir-509-1, hsa-mir-532, hsa-mir-615, hsa-mir-660, bta-mir-127, bta-mir-30e, bta-mir-17, bta-mir-450a-2, bta-mir-532, bta-mir-363, bta-mir-660, hsa-mir-891a, hsa-mir-892a, hsa-mir-509-2, hsa-mir-450b, hsa-mir-892b, hsa-mir-708, hsa-mir-509-3, hsa-mir-1285-2, hsa-mir-1248, ssc-mir-17, bta-mir-155, bta-mir-188, bta-mir-194-2, bta-mir-196b, bta-mir-223, bta-mir-28, bta-mir-362, bta-mir-367, bta-mir-379, bta-mir-431, bta-mir-493, bta-mir-500, bta-mir-502a-1, bta-mir-502a-2, bta-mir-502b, bta-mir-615, bta-mir-708, bta-mir-1248-1, bta-mir-1248-2, ssc-mir-450a, bta-mir-2320, bta-mir-1388, bta-mir-194-1, bta-mir-450a-1, eca-mir-30e, eca-mir-367, eca-mir-684, eca-mir-196b, eca-mir-615, eca-mir-708, eca-mir-194-1, eca-mir-493a, eca-mir-17, eca-mir-1248, eca-mir-28, eca-mir-127, eca-mir-379, eca-mir-431, eca-mir-493b, eca-mir-155, eca-mir-194-2, eca-mir-188, eca-mir-223, eca-mir-362, eca-mir-363, eca-mir-450a, eca-mir-450b, eca-mir-450c, eca-mir-500-1, eca-mir-500-2, eca-mir-501, eca-mir-502, eca-mir-508, eca-mir-509a, eca-mir-532, eca-mir-660, ssc-mir-30e, ssc-mir-196b-1, ssc-mir-450b, ssc-mir-127, ssc-mir-532, ssc-mir-708, ssc-mir-1285, ssc-mir-500, hsa-mir-514b, ssc-mir-363-1, ssc-mir-450c, hsa-mir-500b, ssc-mir-194b, ssc-mir-155, ssc-mir-362, bta-mir-3601, ssc-mir-615, ssc-mir-2320, bta-mir-450b, ssc-mir-194a, ssc-mir-196b-2, ssc-mir-363-2, ssc-mir-493, hsa-mir-892c, eca-mir-1388, eca-mir-514b, eca-mir-506a, eca-mir-509b, bta-mir-194b, ssc-mir-1388, ssc-mir-223, ssc-mir-660, bta-mir-194b-2, bta-mir-1949
That is, some miRNA and one of the following snoRNAs: SNORA36, SNORA81, SCARNA4, SNORD59, SNORA53, SCARNA15, and SNORA18; Mir-1285 and Metazoa _SRP; and finally 28S rRNA and 4 different miRNAs. [score:1]
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[+] score: 1
Other miRNAs from this paper: hsa-mir-25, hsa-mir-28, hsa-mir-95, mmu-mir-151, mmu-mir-290a, mmu-mir-297a-1, mmu-mir-297a-2, mmu-mir-130b, mmu-mir-340, mmu-mir-25, mmu-mir-28a, hsa-mir-130b, hsa-mir-367, hsa-mir-372, hsa-mir-378a, mmu-mir-378a, hsa-mir-340, hsa-mir-151a, mmu-mir-466a, mmu-mir-467a-1, hsa-mir-505, hsa-mir-506, mmu-mir-367, hsa-mir-92b, hsa-mir-548a-1, hsa-mir-548b, hsa-mir-548a-2, hsa-mir-548a-3, hsa-mir-548c, hsa-mir-648, hsa-mir-548d-1, hsa-mir-548d-2, hsa-mir-659, hsa-mir-421, hsa-mir-151b, hsa-mir-1271, hsa-mir-378d-2, mmu-mir-467b, mmu-mir-297b, mmu-mir-505, mmu-mir-297a-3, mmu-mir-297a-4, mmu-mir-297c, mmu-mir-421, mmu-mir-466b-1, mmu-mir-466b-2, mmu-mir-466b-3, mmu-mir-466c-1, mmu-mir-466e, mmu-mir-466f-1, mmu-mir-466f-2, mmu-mir-466f-3, mmu-mir-466g, mmu-mir-466h, mmu-mir-467c, mmu-mir-467d, mmu-mir-92b, mmu-mir-466d, hsa-mir-297, mmu-mir-467e, mmu-mir-466l, mmu-mir-669g, mmu-mir-466i, mmu-mir-466f-4, mmu-mir-466k, mmu-mir-467f, mmu-mir-466j, mmu-mir-467g, mmu-mir-467h, mmu-mir-1195, hsa-mir-548e, hsa-mir-548j, hsa-mir-1285-2, hsa-mir-1289-1, hsa-mir-1289-2, hsa-mir-548k, hsa-mir-1299, hsa-mir-548l, hsa-mir-1302-1, hsa-mir-1302-2, hsa-mir-1302-3, hsa-mir-1302-4, hsa-mir-1302-5, hsa-mir-1302-6, hsa-mir-1302-7, hsa-mir-1302-8, hsa-mir-548f-1, hsa-mir-548f-2, hsa-mir-548f-3, hsa-mir-548f-4, hsa-mir-548f-5, hsa-mir-1255a, hsa-mir-548g, hsa-mir-548n, hsa-mir-548m, hsa-mir-548o, hsa-mir-1268a, hsa-mir-548h-1, hsa-mir-548h-2, hsa-mir-548h-3, hsa-mir-548h-4, hsa-mir-548p, hsa-mir-548i-1, hsa-mir-548i-2, hsa-mir-548i-3, hsa-mir-548i-4, hsa-mir-1255b-1, hsa-mir-1255b-2, mmu-mir-1906-1, hsa-mir-1972-1, hsa-mir-548q, mmu-mir-466m, mmu-mir-466o, mmu-mir-467a-2, mmu-mir-467a-3, mmu-mir-466c-2, mmu-mir-467a-4, mmu-mir-466b-4, mmu-mir-467a-5, mmu-mir-466b-5, mmu-mir-467a-6, mmu-mir-466b-6, mmu-mir-467a-7, mmu-mir-466b-7, mmu-mir-467a-8, mmu-mir-467a-9, mmu-mir-467a-10, mmu-mir-466p, mmu-mir-466n, mmu-mir-466b-8, hsa-mir-3116-1, hsa-mir-3116-2, hsa-mir-3118-1, hsa-mir-3118-2, hsa-mir-3118-3, hsa-mir-548s, hsa-mir-378b, hsa-mir-466, hsa-mir-548t, hsa-mir-548u, hsa-mir-548v, hsa-mir-3156-1, hsa-mir-3118-4, hsa-mir-3174, hsa-mir-3179-1, hsa-mir-3179-2, hsa-mir-3179-3, hsa-mir-548w, hsa-mir-3156-2, hsa-mir-3156-3, hsa-mir-548x, mmu-mir-3470a, mmu-mir-3470b, mmu-mir-3471-1, mmu-mir-3471-2, hsa-mir-378c, hsa-mir-1972-2, hsa-mir-1302-9, hsa-mir-1302-10, hsa-mir-1302-11, mmu-mir-1906-2, hsa-mir-3683, hsa-mir-3690-1, hsa-mir-548y, hsa-mir-548z, hsa-mir-548aa-1, hsa-mir-548aa-2, hsa-mir-548o-2, hsa-mir-1268b, hsa-mir-378d-1, hsa-mir-378e, hsa-mir-548h-5, hsa-mir-548ab, hsa-mir-378f, hsa-mir-378g, hsa-mir-548ac, hsa-mir-548ad, hsa-mir-548ae-1, hsa-mir-548ae-2, hsa-mir-548ag-1, hsa-mir-548ag-2, hsa-mir-548ah, hsa-mir-378h, hsa-mir-548ai, hsa-mir-548aj-1, hsa-mir-548aj-2, hsa-mir-548x-2, hsa-mir-548ak, hsa-mir-548al, hsa-mir-378i, hsa-mir-548am, hsa-mir-548an, mmu-mir-28c, mmu-mir-378b, mmu-mir-28b, hsa-mir-548ao, hsa-mir-548ap, mmu-mir-466q, hsa-mir-548aq, hsa-mir-548ar, hsa-mir-548as, hsa-mir-548at, hsa-mir-548au, hsa-mir-548av, hsa-mir-548aw, hsa-mir-548ax, hsa-mir-378j, mmu-mir-378c, mmu-mir-378d, hsa-mir-548ay, hsa-mir-548az, hsa-mir-3690-2, mmu-mir-290b, hsa-mir-548ba, hsa-mir-548bb, hsa-mir-3179-4, mmu-mir-466c-3, hsa-mir-548bc, mmu-mir-1271
Although, in the present study, the mir-1285, mir-1289 and mir-3116 families are only appear in human, the mir-1285 and mir-3116 families are actually primate-specific miRNA families, and the mir-1289 family is not limited to primate species, but is also found in horse (eca-mir-1289). [score:1]
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Four microRNAs, including miR-9, miR-1285-3p, miR-424-3p, and miR-182-5p, were filtered in all three comparisons. [score:1]
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In addition, a series of miRNAs (including miR-34a, miR-145, miR-205, miR-708, miR-1285 and miR-1826) have been shown to modulate the viability, proliferation, invasion and metastasis of RCC cells [12- 17]. [score:1]
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