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4 publications mentioning gga-mir-454

Open access articles that are associated with the species Gallus gallus and mention the gene name mir-454. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 31
a ADIPOR2 is targeted by miR-20b and let-7c, b INSIG1 is targeted by miR-182, miR-183, and miR-454, c MAPK4K4 is targeted by miR-29a, d FASN is targeted by miR-107, e FADS2 is targeted by let-7c, f ELOVL2 is targeted by miR-10b, g HMGCS1 is targeted by miR-18a, and h MSMO1 is targeted by miR-20b and miR-454 To further explore miRNA regulatory networks associated with the metabolic switch, we identified potential metabolic mRNA targets for let-7c, miR-20b, and miR-183 using in silico target prediction in combination with IPA pathway analysis. [score:22]
MSMO1 mRNA was increased 15-fold in the posthatch liver and is targeted by two downregulated miRNAs, miR-20b and miR-454 (Fig. 3h). [score:6]
INSIG1 mRNA is a predicted target of three miRNAs (miR-182, miR-183, and miR-454), all of which decreased 2-fold between D1 and D3 (Figs. 1 and 3b). [score:3]
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2
[+] score: 15
Moreover, miR-454, a target miRNA of Smad4, was found to be down-regulated in S. japonicum -induced murine liver fibrosis mo dels, while α-SMA and Smad4 were up-regulated (Zhu et al., 2014); these results suggested that the down-regulation of miR-454 may be involved in the pathogenesis of liver fibrosis in S. japonicum-infected mice. [score:12]
Expression of microRNA-454 in TGF-β1-stimulated hepatic stellate cells and in mouse livers infected with Schistosoma japonicum. [score:3]
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3
[+] score: 14
In 7-week-old chickens, as compared with 14-day-old embryos, the expression of let-7b, miR-30a-5p, miR-30b, miR-99a and miR-133b was significantly up-regulated, but miR-16c, miR-92, miR-106, miR-203, miR-451 and miR-454 were significantly down-regulated in both dwarf and normal chickens. [score:8]
The expression of miR-16c, miR-92, miR-106, miR-203, miR-451, and miR-454 was commonly down-regulated (Table  2). [score:6]
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4
[+] score: 11
The most significantly differentially expressed were gga-miR-206 (3.5-fold), gga-miR-31 (2.5-fold), gga-miR-3535 (2.5-fold), gga-miR-17–3p (2.3-fold), gga-miR-429 (2.3-fold) and gga-miR-200b (2.2-fold), and in comparison, gga-miR-454 (-2.9-fold) and gga-miR-1b (-2.7-fold) were those mostly down-regulated in the fat line (Fig. 4). [score:6]
Last but not least, expression levels of 10 miRNAs can be perturbed in animals when fed with high-fat diet (miR-142–5p and miR-101) [74– 78], or with obesity or obesity-related diseases (miR-10a, miR-218, miR-429, miR-200a, miR-200b, miR-451, miR-142–3p, and miR-454) [77, 79– 85], which indicates that they could be potentially related to adipogenesis. [score:5]
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