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3 publications mentioning ccr-mir-27a

Open access articles that are associated with the species Cyprinus carpio and mention the gene name mir-27a. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 24
miR-21 is a key determinant in the IL-11/Stat3 anti-apoptotic signaling pathway involved in the preconditioning of skeletal myoblasts [25], miR-26a targets Ezh2 during myogenesis [44], miR-27 regulates behaviors of muscle stem cells by repression of Pax3 expression [45], miR-214 promotes myogenic differentiation by facilitating exit from mitosis via down-regulation of proto-oncogene N-ras [38], and miR-221 and miR-222 modulate differentiation and maturation of skeletal muscle cells by targeting p27 [41]. [score:11]
miR-27a, miR-214, and miR-222 are expressed at relatively high levels in the 30 dph skeletal muscles, and then decreased in the 1-year and 2-year skeletal muscles (Figure 5). [score:3]
Of note, half of detected miRNAs (miR-21, miR-26a, miR-27a, and miR-214) were expressed at a higher level in the fertilized oocytes than in embryos after fertilization (Figure S3); this is likely caused by the existence of maternal miRNAs or dicer. [score:3]
Importantly, miR-23a, miR-24, miR-27a, and miR-214 were highly expressed in muscle-related tissue or organs (skeletal muscle, heart, gut), although they could also be detected in non-muscle organs (Fig. 4B). [score:3]
We then selected miR-1, miR-21, miR-23a, miR-24, miR-26a, miR-27a, miR-133a-3p, miR-181a-5p, miR-206, miR-214, and miR-222, which have been reported to play roles in the development of vertebrate skeletal muscle (Table 3). [score:2]
These results indicate that miR-27a, miR-214, and miR-222 are related to the process of skeletal muscle proliferation and differentiation in the common carp. [score:1]
Other muscle-related miRNAs in vertebrates, including miR-21, miR-214, miR-26, miR-27, miR-221, and miR-222, have also been identified in the common carp. [score:1]
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2
[+] score: 9
In addition, up-regulation of miR-27 members suggests a possible role of this family during ovary development. [score:5]
MiR-27 may be involved in the regulation of cell proliferation and differentiation in vertebrates, but has not been found in invertebrates. [score:1]
Five members of the miR-27 family have been identified to date, including three in pufferfish (Fugu rubripes and Tetraodon nigroviridis), four (hno-miR-27a, hon-miR-27b, hno-miR-27d, hno-miR-27e) in bighead and silver carp [54], and five (dre-miR-27a, dre-miR-27b, dre-miR-27c, dre-miR-27d, dre-miR-27e) in zebrafish [53]. [score:1]
We found five members of the miR-27 family in Yellow River carp, including ccr-miR-27a, ccr-miR-27c-3p, ccr-miR-27c-5p, ccr-miR-27d, miR-27-5p, and miR-27-3p. [score:1]
It has been suggested that miR-27 may have originated in fish [54]. [score:1]
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3
[+] score: 6
Different members of these miRNA families were presented in different lineages ranging from urochordates to mammals, as we can see in Table 2. miR-27 was not found in sea squirt or any other invertebrates, indicating that the miR-27 gene likely originated in fishes. [score:1]
Sequence comparison of miR-27, miR-30 and miR-181 family members in zebrafish and human. [score:1]
Up to now, five members of the miR-27 family have been found. [score:1]
Alignments were carried out within miR-27, miR-30 and miR-181 family of zebrafish and human, respectively (Figure 7). [score:1]
miR-27, miR-30 and miR-181 family members in different lineages. [score:1]
Three miRNA families, miR-27, miR-30 and miR-181, were analyzed to determine gain and loss of miRNA family members and changes in their sequences (miRNA sequences were downloaded from miRBase). [score:1]
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