sort by

1 publications mentioning ipu-mir-181a-5

Open access articles that are associated with the species Ictalurus punctatus and mention the gene name mir-181a-5. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 27
Cichocki et al. demonstrated that nemo-like kinase (NLK), an inhibitor of Notch signaling, is a target of miR-181 in natural killer cell (NK) cells, and knockdown of NLK mirrors the developmental effect of miR-181 overexpression. [score:9]
Li et al. found that increasing miR-181a expression in mature T cells augments their sensitivity to peptide antigens, while inhibiting miR-181a expression in immature T cells reduces sensitivity and impairs both positive and negative selection [28]. [score:7]
Therefore, they concluded that miR-181 can promote NK cell development, at least in part, through the suppression of NLK [29]. [score:4]
Studies on these miRNAs in mammals indicate that miR-181 is involved in multiple roles in immune regulation and disease. [score:4]
The most highly expressed miRNA family in channel catfish was ipu-miR-181 (1,781,434 reads). [score:3]
[1 to 20 of 5 sentences]