ID cel-let-7 standard; RNA; CEL; 99 BP.
XX
AC MI0000001;
XX
DE Caenorhabditis elegans let-7 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 12769849.
RA Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J;
RT "Computational and experimental identification of C. elegans microRNAs";
RL Mol Cell. 11:1253-1263(2003).
XX
RN [5]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [6]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [7]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR RFAM; RF00027; let-7.
DR WORMBASE; C05G5/12462-12364; .
XX
CC let-7 is found on chromosome X in Caenorhabditis elegans [1] and pairs to
CC sites within the 3' untranslated region (UTR) of target mRNAs, specifying
CC the translational repression of these mRNAs and triggering the transition
CC to late-larval and adult stages [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 17..38
FT /accession="MIMAT0000001"
FT /product="cel-let-7-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Northern [1], PCR [4], 454 [5],
FT Illumina [6], CLIPseq [7]"
FT miRNA 60..81
FT /accession="MIMAT0015091"
FT /product="cel-let-7-3p"
FT /evidence=experimental
FT /experiment="CLIPseq [7]"
XX
SQ Sequence 99 BP; 26 A; 19 C; 24 G; 0 T; 30 other;
uacacugugg auccggugag guaguagguu guauaguuug gaauauuacc accggugaac 60
uaugcaauuu ucuaccuuac cggagacaga acucuucga 99
//
ID cel-lin-4 standard; RNA; CEL; 94 BP.
XX
AC MI0000002;
XX
DE Caenorhabditis elegans lin-4 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 10642801.
RA Olsen PH, Ambros V;
RT "The lin-4 regulatory RNA controls developmental timing in Caenorhabditis
RT elegans by blocking LIN-14 protein synthesis after the initiation of
RT translation";
RL Dev Biol. 216:671-680(1999).
XX
RN [3]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [4]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [5]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [6]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [7]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR RFAM; RF00052; lin-4.
DR WORMBASE; F59G1/6156-6249; .
XX
CC lin-4 is found on chromosome II in Caenorhabditis elegans [1] and is
CC complementary to sequences in the 3' untranslated region (UTR) of lin-14
CC mRNA. lin-4 acts to developmentally repress the accumulation of lin-14
CC protein. This repression is essential for the proper timing of numerous
CC events of Caenorhabditis elegans larval development [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..36
FT /accession="MIMAT0000002"
FT /product="cel-lin-4-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3-4], 454 [5], Illumina [6],
FT CLIPseq [7]"
FT miRNA 55..76
FT /accession="MIMAT0015092"
FT /product="cel-lin-4-3p"
FT /evidence=experimental
FT /experiment="CLIPseq [7]"
XX
SQ Sequence 94 BP; 17 A; 25 C; 26 G; 0 T; 26 other;
augcuuccgg ccuguucccu gagaccucaa gugugagugu acuauugaug cuucacaccu 60
gggcucuccg gguaccagga cgguuugagc agau 94
//
ID cel-mir-1 standard; RNA; CEL; 96 BP.
XX
AC MI0000003;
XX
DE Caenorhabditis elegans miR-1 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 11679672.
RA Lee RC, Ambros V;
RT "An extensive class of small RNAs in Caenorhabditis elegans";
RL Science. 294:862-864(2001).
XX
RN [3]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [4]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [5]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [6]
RX PUBMED; 12769849.
RA Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J;
RT "Computational and experimental identification of C. elegans microRNAs";
RL Mol Cell. 11:1253-1263(2003).
XX
RN [7]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [8]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [9]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [10]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR RFAM; RF00103; mir-1.
DR WORMBASE; T09B4/23107-23012; .
XX
CC miR-1 was independently identified in C. elegans [1,2] and Drosophila
CC melanogaster (MIR:MI0000116) [3]. The sequence is also conserved in C.
CC briggsae (MIR:MI0000493).
XX
FH Key Location/Qualifiers
FH
FT miRNA 21..42
FT /accession="MIMAT0020301"
FT /product="cel-miR-1-5p"
FT /evidence=experimental
FT /experiment="Illumina [10]"
FT miRNA 61..81
FT /accession="MIMAT0000003"
FT /product="cel-miR-1-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2,4-5], Northern [1], Illumina
FT [10,8], PCR [6], 454 [7], CLIPseq [9]"
XX
SQ Sequence 96 BP; 32 A; 16 C; 23 G; 0 T; 25 other;
aaagugaccg uaccgagcug cauacuuccu uacaugccca uacuauauca uaaauggaua 60
uggaauguaa agaaguaugu agaacggggu gguagu 96
//
ID cel-mir-2 standard; RNA; CEL; 98 BP.
XX
AC MI0000004;
XX
DE Caenorhabditis elegans miR-2 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 11679672.
RA Lee RC, Ambros V;
RT "An extensive class of small RNAs in Caenorhabditis elegans";
RL Science. 294:862-864(2001).
XX
RN [3]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [4]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [5]
RX PUBMED; 12769849.
RA Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J;
RT "Computational and experimental identification of C. elegans microRNAs";
RL Mol Cell. 11:1253-1263(2003).
XX
RN [6]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [7]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [8]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [9]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR RFAM; RF00047; mir-2.
DR WORMBASE; M04C9/29652-29555; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 20..41
FT /accession="MIMAT0020302"
FT /product="cel-miR-2-5p"
FT /evidence=experimental
FT /experiment="Illumina [9]"
FT miRNA 61..83
FT /accession="MIMAT0000004"
FT /product="cel-miR-2-3p"
FT /evidence=experimental
FT /experiment="cloned [1-4], PCR [5], 454 [6], Illumina
FT [7,9], CLIPseq [8]"
XX
SQ Sequence 98 BP; 27 A; 19 C; 22 G; 0 T; 30 other;
uaaacaguau acagaaagcc aucaaagcgg ugguugaugu guugcaaauu augacuuuca 60
uaucacagcc agcuuugaug ugcugccugu ugcacugu 98
//
ID cel-mir-34 standard; RNA; CEL; 97 BP.
XX
AC MI0000005;
XX
DE Caenorhabditis elegans miR-34 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 12769849.
RA Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J;
RT "Computational and experimental identification of C. elegans microRNAs";
RL Mol Cell. 11:1253-1263(2003).
XX
RN [5]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [6]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [7]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR WORMBASE; Y41G9A/23565-23469; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..37
FT /accession="MIMAT0000005"
FT /product="cel-miR-34-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Northern [1], PCR [4], 454 [5],
FT Illumina [6], CLIPseq [7]"
FT miRNA 53..74
FT /accession="MIMAT0015093"
FT /product="cel-miR-34-3p"
FT /evidence=experimental
FT /experiment="CLIPseq [7]"
XX
SQ Sequence 97 BP; 21 A; 27 C; 23 G; 0 T; 26 other;
cggacaaugc ucgagaggca gugugguuag cugguugcau auuuccuuga caacggcuac 60
cuucacugcc accccgaaca ugucguccau cuuugaa 97
//
ID cel-mir-35 standard; RNA; CEL; 97 BP.
XX
AC MI0000006;
XX
DE Caenorhabditis elegans miR-35 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [5]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [6]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [7]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; Y62F5A/16840-16936; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 22..44
FT /accession="MIMAT0020303"
FT /product="cel-miR-35-5p"
FT /evidence=experimental
FT /experiment="Illumina [7]"
FT miRNA 61..82
FT /accession="MIMAT0000006"
FT /product="cel-miR-35-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Northern [1], 454 [4], Illumina
FT [5,7], CLIPseq [6]"
XX
SQ Sequence 97 BP; 20 A; 25 C; 22 G; 0 T; 30 other;
ucucggauca gaucgagcca uugcugguuu cuuccacagu gguacuuucc auuagaacua 60
ucaccgggug gaaacuagca guggcucgau cuuuucc 97
//
ID cel-mir-36 standard; RNA; CEL; 97 BP.
XX
AC MI0000007;
XX
DE Caenorhabditis elegans miR-36 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [6]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; Y62F5A/16945-17041; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 20..42
FT /accession="MIMAT0020304"
FT /product="cel-miR-36-5p"
FT /evidence=experimental
FT /experiment="Illumina [6]"
FT miRNA 61..82
FT /accession="MIMAT0000007"
FT /product="cel-miR-36-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1], 454 [3], Illumina
FT [4,6], CLIPseq [5]"
XX
SQ Sequence 97 BP; 21 A; 30 C; 26 G; 0 T; 20 other;
caccgcuguc ggggaaccgc gccaauuuuc gcuucagugc uagaccaucc aaagugucua 60
ucaccgggug aaaauucgca uggguccccg acgcgga 97
//
ID cel-mir-37 standard; RNA; CEL; 98 BP.
XX
AC MI0000008;
XX
DE Caenorhabditis elegans miR-37 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [5]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [6]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR WORMBASE; Y62F5A/17065-17162; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 22..44
FT /accession="MIMAT0015094"
FT /product="cel-miR-37-5p"
FT /evidence=experimental
FT /experiment="CLIPseq [6]"
FT miRNA 61..82
FT /accession="MIMAT0000008"
FT /product="cel-miR-37-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Northern [1], 454 [4], Illumina
FT [5], CLIPseq [6]"
XX
SQ Sequence 98 BP; 16 A; 24 C; 26 G; 0 T; 32 other;
uucuagaaac ccuuggacca gugugggugu ccguugcggu gcuacauucu cuaaucugua 60
ucaccgggug aacacuugca gugguccucg ugguuucu 98
//
ID cel-mir-38 standard; RNA; CEL; 95 BP.
XX
AC MI0000009;
XX
DE Caenorhabditis elegans miR-38 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [5]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [6]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [7]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; Y62F5A/17162-17259; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 17..38
FT /accession="MIMAT0020305"
FT /product="cel-miR-38-5p"
FT /evidence=experimental
FT /experiment="Illumina [7]"
FT miRNA 58..79
FT /accession="MIMAT0000009"
FT /product="cel-miR-38-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Northern [1], 454 [4], Illumina
FT [5,7], CLIPseq [6]"
XX
SQ Sequence 95 BP; 23 A; 22 C; 25 G; 0 T; 25 other;
gugagccagg uccuguuccg guuuuuuccg uggugauaac gcauccaaaa gucucuauca 60
ccgggagaaa aacuggagua ggaccuguga cucau 95
//
ID cel-mir-39 standard; RNA; CEL; 87 BP.
XX
AC MI0000010;
XX
DE Caenorhabditis elegans miR-39 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [6]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; Y62F5A/17315-17412; .
XX
CC The excised miRNA sequence was initially predicted [1], and confirmed
CC later by sequencing [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 15..36
FT /accession="MIMAT0020306"
FT /product="cel-miR-39-5p"
FT /evidence=experimental
FT /experiment="Illumina [6]"
FT miRNA 55..76
FT /accession="MIMAT0000010"
FT /product="cel-miR-39-3p"
FT /evidence=experimental
FT /experiment="Northern [1], cloned [2], 454 [3], Illumina
FT [4,6], CLIPseq [5]"
XX
SQ Sequence 87 BP; 19 A; 19 C; 22 G; 0 T; 27 other;
uauaccgaga gcccagcuga uuucgucuug guaauaagcu cgucauugag auuaucaccg 60
gguguaaauc agcuuggcuc ugguguc 87
//
ID cel-mir-40 standard; RNA; CEL; 92 BP.
XX
AC MI0000011;
XX
DE Caenorhabditis elegans miR-40 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [5]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [6]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [7]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; Y62F5A/17411-17507; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..38
FT /accession="MIMAT0020307"
FT /product="cel-miR-40-5p"
FT /evidence=experimental
FT /experiment="Illumina [7]"
FT miRNA 56..77
FT /accession="MIMAT0000011"
FT /product="cel-miR-40-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Northern [1], 454 [4], Illumina
FT [5,7], CLIPseq [6]"
XX
SQ Sequence 92 BP; 24 A; 21 C; 24 G; 0 T; 23 other;
uccuguccgc accucagugg auguaugcca ugaugauaag auaucagaaa uccuaucacc 60
ggguguacau cagcuaaggu gcggguacag gu 92
//
ID cel-mir-41 standard; RNA; CEL; 97 BP.
XX
AC MI0000012;
XX
DE Caenorhabditis elegans miR-41 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [6]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; Y62F5A/17540-17636; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 17..39
FT /accession="MIMAT0020770"
FT /product="cel-miR-41-5p"
FT /evidence=experimental
FT /experiment="Illumina [6]"
FT miRNA 61..82
FT /accession="MIMAT0000012"
FT /product="cel-miR-41-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], 454 [3], Illumina [4,6],
FT CLIPseq [5]"
XX
SQ Sequence 97 BP; 22 A; 25 C; 23 G; 0 T; 27 other;
gggucccaga gaccuuggug guuuuucucu gcagugauag auacuucuaa caacucgcua 60
ucaccgggug aaaaaucacc uaggucugga gccuccu 97
//
ID cel-mir-42 standard; RNA; CEL; 95 BP.
XX
AC MI0000013;
XX
DE Caenorhabditis elegans miR-42 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 11679672.
RA Lee RC, Ambros V;
RT "An extensive class of small RNAs in Caenorhabditis elegans";
RL Science. 294:862-864(2001).
XX
RN [3]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [4]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [5]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [6]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [7]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR WORMBASE; ZK930/12429-12523; .
XX
CC The extents of the dominant mature miRNA species are adjusted here in
CC accordance with a large scale cloning and sequencing study [5].
XX
FH Key Location/Qualifiers
FH
FT miRNA 14..38
FT /accession="MIMAT0015095"
FT /product="cel-miR-42-5p"
FT /evidence=experimental
FT /experiment="CLIPseq [7]"
FT miRNA 60..81
FT /accession="MIMAT0000013"
FT /product="cel-miR-42-3p"
FT /evidence=experimental
FT /experiment="cloned [1-4], Northern [1], 454 [5], Illumina
FT [6], CLIPseq [7]"
XX
SQ Sequence 95 BP; 16 A; 20 C; 26 G; 0 T; 33 other;
uucgcggacc uuugugggug uuugcuuuuu cggugaaguu gucuuccgua gcuucuucuu 60
caccggguua acaucuacag agguccaaaa agggg 95
//
ID cel-mir-43 standard; RNA; CEL; 98 BP.
XX
AC MI0000014;
XX
DE Caenorhabditis elegans miR-43 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 11679672.
RA Lee RC, Ambros V;
RT "An extensive class of small RNAs in Caenorhabditis elegans";
RL Science. 294:862-864(2001).
XX
RN [3]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [4]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [5]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [6]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [7]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; ZK930/12528-12625; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 21..44
FT /accession="MIMAT0020308"
FT /product="cel-miR-43-5p"
FT /evidence=experimental
FT /experiment="Illumina [7]"
FT miRNA 61..83
FT /accession="MIMAT0000014"
FT /product="cel-miR-43-3p"
FT /evidence=experimental
FT /experiment="cloned [1-4], Northern [1], 454 [5], Illumina
FT [6-7]"
XX
SQ Sequence 98 BP; 25 A; 23 C; 25 G; 0 T; 25 other;
uauuggcacu agucgcccgu gacaucaaga aacuagugau uaugccaaac cacagggaca 60
uaucacaguu uacuugcugu cgcgggcggu gcugaguu 98
//
ID cel-mir-44 standard; RNA; CEL; 96 BP.
XX
AC MI0000015;
XX
DE Caenorhabditis elegans miR-44 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [5]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [6]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [7]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; ZK930/12641-12736; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..37
FT /accession="MIMAT0020771"
FT /product="cel-miR-44-5p"
FT /evidence=experimental
FT /experiment="Illumina [7]"
FT miRNA 61..81
FT /accession="MIMAT0000015"
FT /product="cel-miR-44-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Northern [1], 454 [4], Illumina
FT [5,7], CLIPseq [6]"
XX
SQ Sequence 96 BP; 26 A; 22 C; 22 G; 0 T; 26 other;
gagaaaaugg ccaaucugga ugugcucguu ggucauagac gucaacacga acuguucaua 60
ugacuagaga cacauucagc uuggccugcu ucucua 96
//
ID cel-mir-45 standard; RNA; CEL; 96 BP.
XX
AC MI0000016;
XX
DE Caenorhabditis elegans miR-45 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [5]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [6]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [7]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; ZK930/3657-3562; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 15..36
FT /accession="MIMAT0020772"
FT /product="cel-miR-45-5p"
FT /evidence=experimental
FT /experiment="Illumina [7]"
FT miRNA 61..81
FT /accession="MIMAT0000016"
FT /product="cel-miR-45-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Northern [1], 454 [4], Illumina
FT [5,7], CLIPseq [6]"
XX
SQ Sequence 96 BP; 27 A; 26 C; 21 G; 0 T; 22 other;
caccaugugc cacgcuggau gugcucguua gucauaauau ccuccacaaa gcaaggacua 60
ugacuagaga cacauucagc uuggcgccga augcau 96
//
ID cel-mir-46 standard; RNA; CEL; 97 BP.
XX
AC MI0000017;
XX
DE Caenorhabditis elegans miR-46 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [5]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [6]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [7]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; ZK525/4728-4824; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 15..36
FT /accession="MIMAT0015096"
FT /product="cel-miR-46-5p"
FT /evidence=experimental
FT /experiment="CLIPseq [6], Illumina [7]"
FT miRNA 61..82
FT /accession="MIMAT0000017"
FT /product="cel-miR-46-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Northern [1], 454 [4], Illumina
FT [5,7], CLIPseq [6]"
XX
SQ Sequence 97 BP; 22 A; 21 C; 28 G; 0 T; 26 other;
cugaggugaa gcugaagaga gccgucuauu gacaguucaa gaccacgagu cguugugugc 60
ugucauggag ucgcucucuu cagaugaucc ggucaau 97
//
ID cel-mir-47 standard; RNA; CEL; 97 BP.
XX
AC MI0000018;
XX
DE Caenorhabditis elegans miR-47 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 12769849.
RA Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J;
RT "Computational and experimental identification of C. elegans microRNAs";
RL Mol Cell. 11:1253-1263(2003).
XX
RN [5]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [6]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [7]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR WORMBASE; K02B9/506-602; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 19..40
FT /accession="MIMAT0015097"
FT /product="cel-miR-47-5p"
FT /evidence=experimental
FT /experiment="CLIPseq [7]"
FT miRNA 61..82
FT /accession="MIMAT0000018"
FT /product="cel-miR-47-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Northern [1], PCR [4], 454 [5],
FT Illumina [6], CLIPseq [7]"
XX
SQ Sequence 97 BP; 24 A; 22 C; 26 G; 0 T; 25 other;
gagagccgac ugaaacugaa gagagcaguc uauugacagu cgguuacucg aaaucuuuac 60
ugucauggag gcgcucucuu cagaugaugu cuggccc 97
//
ID cel-mir-48 standard; RNA; CEL; 98 BP.
XX
AC MI0000019;
XX
DE Caenorhabditis elegans miR-48 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [5]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [6]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR WORMBASE; WBGene00003039; lin-58.
DR ENTREZGENE; 260115; lin-58.
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..38
FT /accession="MIMAT0000019"
FT /product="cel-miR-48-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3], 454 [4], Illumina [5], CLIPseq
FT [6]"
FT miRNA 54..75
FT /accession="MIMAT0015098"
FT /product="cel-miR-48-3p"
FT /evidence=experimental
FT /experiment="CLIPseq [6]"
XX
SQ Sequence 98 BP; 25 A; 25 C; 23 G; 0 T; 25 other;
aaacucccgg gaacuugagg uaggcucagu agaugcgaau ugaacgguau cucacaucca 60
ccagccuagc ucgcauuccc agaguuuacg guauuguu 98
//
ID cel-mir-49 standard; RNA; CEL; 97 BP.
XX
AC MI0000020;
XX
DE Caenorhabditis elegans miR-49 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [6]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; F19C6/9366-9462; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 21..43
FT /accession="MIMAT0020309"
FT /product="cel-miR-49-5p"
FT /evidence=experimental
FT /experiment="Illumina [6]"
FT miRNA 61..82
FT /accession="MIMAT0000020"
FT /product="cel-miR-49-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], 454 [3], Illumina [4,6],
FT CLIPseq [5]"
XX
SQ Sequence 97 BP; 26 A; 20 C; 25 G; 0 T; 26 other;
uuuugaaaaa gaccaccguc cgcaguuugu ugugaugugc uccaagcaau caugagucug 60
aagcaccacg agaagcugca gauggagguu cugauuu 97
//
ID cel-mir-50 standard; RNA; CEL; 99 BP.
XX
AC MI0000021;
XX
DE Caenorhabditis elegans miR-50 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [6]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; Y71G12B/98208-98306; .
XX
CC The extents of the dominant mature miRNA species are adjusted here in
CC accordance with a large scale cloning and sequencing study [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..39
FT /accession="MIMAT0000021"
FT /product="cel-miR-50-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], 454 [3], Illumina [4,6],
FT CLIPseq [5]"
FT miRNA 58..79
FT /accession="MIMAT0020310"
FT /product="cel-miR-50-3p"
FT /evidence=experimental
FT /experiment="Illumina [6]"
XX
SQ Sequence 99 BP; 17 A; 26 C; 31 G; 0 T; 25 other;
cugcccgccg gccgcugaua ugucugguau ucuuggguuu gaacuuccag cguugaaccc 60
gcauauuaga cguaucgacg gccggcgggg cagguaaug 99
//
ID cel-mir-51 standard; RNA; CEL; 100 BP.
XX
AC MI0000022;
XX
DE Caenorhabditis elegans miR-51 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [5]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [6]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR RFAM; RF00104; mir-10.
DR WORMBASE; F36H1/2915-2816; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 17..39
FT /accession="MIMAT0000022"
FT /product="cel-miR-51-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3], 454 [4], Illumina [5], CLIPseq
FT [6]"
FT miRNA 57..78
FT /accession="MIMAT0015099"
FT /product="cel-miR-51-3p"
FT /evidence=experimental
FT /experiment="CLIPseq [6]"
XX
SQ Sequence 100 BP; 28 A; 23 C; 28 G; 0 T; 21 other;
guccgaaaag uccgucuacc cguagcuccu auccauguua cuggucaaaa agugaacaug 60
gaagcaggua caggugcacg gcgaguaggg ucaugaagcu 100
//
ID cel-mir-52 standard; RNA; CEL; 100 BP.
XX
AC MI0000023;
XX
DE Caenorhabditis elegans miR-52 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 11679672.
RA Lee RC, Ambros V;
RT "An extensive class of small RNAs in Caenorhabditis elegans";
RL Science. 294:862-864(2001).
XX
RN [3]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [4]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [5]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [6]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [7]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [8]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; Y37A1B/60854-60953; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 17..40
FT /accession="MIMAT0000023"
FT /product="cel-miR-52-5p"
FT /evidence=experimental
FT /experiment="cloned [1-4], Northern [1], 454 [5], Illumina
FT [6,8], CLIPseq [7]"
FT miRNA 58..79
FT /accession="MIMAT0020311"
FT /product="cel-miR-52-3p"
FT /evidence=experimental
FT /experiment="Illumina [8]"
XX
SQ Sequence 100 BP; 26 A; 24 C; 22 G; 0 T; 28 other;
uccaacucua acaguccacc cguacauaug uuuccgugcu ugacagcgaa gcucaaucac 60
guuacaauga aaggguagcc gguuauugaa guugggucuu 100
//
ID cel-mir-53 standard; RNA; CEL; 99 BP.
XX
AC MI0000024;
XX
DE Caenorhabditis elegans miR-53 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [6]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; F36H1/4494-4396; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..39
FT /accession="MIMAT0000024"
FT /product="cel-miR-53-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], 454 [3], Illumina [4,6],
FT CLIPseq [5]"
FT miRNA 57..78
FT /accession="MIMAT0020312"
FT /product="cel-miR-53-3p"
FT /evidence=experimental
FT /experiment="Illumina [6]"
XX
SQ Sequence 99 BP; 23 A; 26 C; 20 G; 0 T; 30 other;
ccgauucuga caguccaccc guacauuugu uuccgugcuu gacuucaaag cucaaucacg 60
gcacaauaua ugggucgcca gucauuguag ucggaauuu 99
//
ID cel-mir-54 standard; RNA; CEL; 99 BP.
XX
AC MI0000025;
XX
DE Caenorhabditis elegans miR-54 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [5]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [6]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [7]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; F09A5/18644-18546; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 19..40
FT /accession="MIMAT0020773"
FT /product="cel-miR-54-5p"
FT /evidence=experimental
FT /experiment="Illumina [7]"
FT miRNA 61..84
FT /accession="MIMAT0000025"
FT /product="cel-miR-54-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], 454 [4], Illumina [5,7],
FT CLIPseq [6]"
XX
SQ Sequence 99 BP; 27 A; 21 C; 24 G; 0 T; 27 other;
gugagucgcg cucugacuag gauaugagac gacgagaaca uugcuuuuuu aaaagacuug 60
uacccguaau cuucauaauc cgagucaggg cuagcugac 99
//
ID cel-mir-55 standard; RNA; CEL; 98 BP.
XX
AC MI0000026;
XX
DE Caenorhabditis elegans miR-55 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [5]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [6]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; F09A5/18474-18377; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 23..44
FT /accession="MIMAT0020313"
FT /product="cel-miR-55-5p"
FT /evidence=experimental
FT /experiment="Illumina [6]"
FT miRNA 61..83
FT /accession="MIMAT0000026"
FT /product="cel-miR-55-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], 454 [4], Illumina [5-6]"
XX
SQ Sequence 98 BP; 23 A; 20 C; 20 G; 0 T; 35 other;
agauuuggaa cuuaauggga cucggcagaa accuaucggu uauacuuuuu ggauaugcua 60
uacccguaua aguuucugcu gagccccuua uuccuguu 98
//
ID cel-mir-56 standard; RNA; CEL; 97 BP.
XX
AC MI0000027;
XX
DE Caenorhabditis elegans miR-56 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 12769849.
RA Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J;
RT "Computational and experimental identification of C. elegans microRNAs";
RL Mol Cell. 11:1253-1263(2003).
XX
RN [5]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [6]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [7]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR WORMBASE; F09A5/18337-18241; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 18..42
FT /accession="MIMAT0000027"
FT /product="cel-miR-56-5p"
FT /evidence=experimental
FT /experiment="cloned [1], CLIPseq [7]"
FT miRNA 61..82
FT /accession="MIMAT0000028"
FT /product="cel-miR-56-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Northern [1], PCR [4], 454 [5],
FT Illumina [6], CLIPseq [7]"
XX
SQ Sequence 97 BP; 18 A; 25 C; 24 G; 0 T; 30 other;
gagccagugu cuguucuugg cggauccauu uuggguugua ccucauccua aauuugacgg 60
uacccguaau guuuccgcug agaaccgacu gugcacc 97
//
ID cel-mir-57 standard; RNA; CEL; 99 BP.
XX
AC MI0000028;
XX
DE Caenorhabditis elegans miR-57 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [6]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR RFAM; RF00104; mir-10.
DR WORMBASE; T09A5/18697-18599; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..39
FT /accession="MIMAT0000029"
FT /product="cel-miR-57-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], 454 [3], Illumina [4,6],
FT CLIPseq [5]"
FT miRNA 55..76
FT /accession="MIMAT0020314"
FT /product="cel-miR-57-3p"
FT /evidence=experimental
FT /experiment="Illumina [6]"
XX
SQ Sequence 99 BP; 33 A; 22 C; 21 G; 0 T; 23 other;
aucgacaugc ucgucuaccc uguagaucga gcuguguguu ugaaacaauc auacacgagc 60
uagacuacaa ggugcacgaa caaaccgaag auuuaugaa 99
//
ID cel-mir-58a standard; RNA; CEL; 97 BP.
XX
AC MI0000029;
XX
DE Caenorhabditis elegans miR-58 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 11679672.
RA Lee RC, Ambros V;
RT "An extensive class of small RNAs in Caenorhabditis elegans";
RL Science. 294:862-864(2001).
XX
RN [3]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [4]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [5]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [6]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [7]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR WORMBASE; Y67D8A/16188-16284; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..38
FT /accession="MIMAT0015100"
FT /product="cel-miR-58a-5p"
FT /evidence=experimental
FT /experiment="CLIPseq [7]"
FT miRNA 61..82
FT /accession="MIMAT0000030"
FT /product="cel-miR-58a-3p"
FT /evidence=experimental
FT /experiment="cloned [1-4], 454 [5], Illumina [6], CLIPseq
FT [7]"
XX
SQ Sequence 97 BP; 23 A; 27 C; 20 G; 0 T; 27 other;
gcucgucaua uccauugccc uacucuucgc aucucaucac uucguccaau accauaggga 60
ugagaucguu caguacggca auggacugag cuagagu 97
//
ID cel-mir-59 standard; RNA; CEL; 100 BP.
XX
AC MI0000030;
XX
DE Caenorhabditis elegans miR-59 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR WORMBASE; B0035/14964-14865; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 20..41
FT /accession="MIMAT0015101"
FT /product="cel-miR-59-5p"
FT /evidence=experimental
FT /experiment="CLIPseq [5]"
FT miRNA 63..85
FT /accession="MIMAT0000031"
FT /product="cel-miR-59-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], 454 [3], Illumina [4], CLIPseq
FT [5]"
XX
SQ Sequence 100 BP; 38 A; 14 C; 19 G; 0 T; 29 other;
aguugaucua gauaugacau cguccugaaa acgaaacgga acaaaaguuc aagauauuga 60
uuucgaaucg uuuaucagga ugaugugauu aaaaucaacu 100
//
ID cel-mir-60 standard; RNA; CEL; 98 BP.
XX
AC MI0000031;
XX
DE Caenorhabditis elegans miR-60 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 11679672.
RA Lee RC, Ambros V;
RT "An extensive class of small RNAs in Caenorhabditis elegans";
RL Science. 294:862-864(2001).
XX
RN [3]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [4]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [5]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [6]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [7]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR WORMBASE; C32D5/16788-16691; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 22..44
FT /accession="MIMAT0015102"
FT /product="cel-miR-60-5p"
FT /evidence=experimental
FT /experiment="CLIPseq [7]"
FT miRNA 61..83
FT /accession="MIMAT0000032"
FT /product="cel-miR-60-3p"
FT /evidence=experimental
FT /experiment="cloned [1-4], 454 [5], Illumina [6], CLIPseq
FT [7]"
XX
SQ Sequence 98 BP; 33 A; 18 C; 19 G; 0 T; 28 other;
cucgaaaacc gcuuguucuu gaacuggaag agugccauaa aaucaugaca aaguacguga 60
uauuaugcac auuuucuagu ucaagacuug agaaaucg 98
//
ID cel-mir-61 standard; RNA; CEL; 97 BP.
XX
AC MI0000032;
XX
DE Caenorhabditis elegans miR-61 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [5]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [6]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR WORMBASE; F55A11/6731-6635; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 25..46
FT /accession="MIMAT0015103"
FT /product="cel-miR-61-5p"
FT /evidence=experimental
FT /experiment="CLIPseq [6]"
FT miRNA 61..81
FT /accession="MIMAT0000033"
FT /product="cel-miR-61-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], 454 [4], Illumina [5], CLIPseq
FT [6]"
XX
SQ Sequence 97 BP; 19 A; 24 C; 24 G; 0 T; 30 other;
uuccauuauc gcugaaccuc gagauggguu acggggcuua guccuuccuc cguauggcaa 60
ugacuagaac cguuacucau cucgagguuu cggugau 97
//
ID cel-mir-62 standard; RNA; CEL; 58 BP.
XX
AC MI0000033;
XX
DE Caenorhabditis elegans miR-62 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 11679672.
RA Lee RC, Ambros V;
RT "An extensive class of small RNAs in Caenorhabditis elegans";
RL Science. 294:862-864(2001).
XX
RN [3]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [4]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [5]
RX PUBMED; 17589500.
RA Ruby JG, Jan CH, Bartel DP;
RT "Intronic microRNA precursors that bypass Drosha processing";
RL Nature. 448:83-86(2007).
XX
RN [6]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [7]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR WORMBASE; T07C5/11823-11894; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 37..58
FT /accession="MIMAT0000034"
FT /product="cel-miR-62"
FT /evidence=experimental
FT /experiment="cloned [1-3], 454 [4], Illumina [6], CLIPseq
FT [7]"
XX
SQ Sequence 58 BP; 19 A; 10 C; 11 G; 0 T; 18 other;
gugaguuaga ucucauaucc uuccgcaaaa uggaaaugau auguaaucua gcuuacag 58
//
ID cel-mir-63 standard; RNA; CEL; 104 BP.
XX
AC MI0000034;
XX
DE Caenorhabditis elegans miR-63 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR WORMBASE; C16H3/369-266; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 20..42
FT /accession="MIMAT0015104"
FT /product="cel-miR-63-5p"
FT /evidence=experimental
FT /experiment="CLIPseq [5]"
FT miRNA 61..84
FT /accession="MIMAT0000035"
FT /product="cel-miR-63-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], 454 [3], Illumina [4], CLIPseq
FT [5]"
XX
SQ Sequence 104 BP; 34 A; 21 C; 23 G; 0 T; 26 other;
ucaacaagca gacacaauuu cuaacucguc gguagucauc guucuagcug aaaaggacac 60
uaugacacug aagcgaguug gaaauagugg uucuacuuga gcaa 104
//
ID cel-mir-64 standard; RNA; CEL; 110 BP.
XX
AC MI0000035;
XX
DE Caenorhabditis elegans miR-64 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR WORMBASE; Y48G9A/92980-93089; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 22..44
FT /accession="MIMAT0000036"
FT /product="cel-miR-64-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1], 454 [3], Illumina
FT [4], CLIPseq [5]"
FT miRNA 68..88
FT /accession="MIMAT0015105"
FT /product="cel-miR-64-3p"
FT /evidence=experimental
FT /experiment="CLIPseq [5]"
XX
SQ Sequence 110 BP; 24 A; 35 C; 26 G; 0 T; 25 other;
cuccccgcug accucgccga auaugacacu gaagcguuac cgaaccguuu ucccacaccu 60
ggauucggug caacgaucag uggcaugcuc ggcuagcgcc aguuaaguau 110
//
ID cel-mir-65 standard; RNA; CEL; 100 BP.
XX
AC MI0000036;
XX
DE Caenorhabditis elegans miR-65 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [5]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [6]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR WORMBASE; Y48G9A/93134-93233; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 18..40
FT /accession="MIMAT0000037"
FT /product="cel-miR-65-5p"
FT /evidence=experimental
FT /experiment="Northern [1], cloned [2-3], 454 [4], Illumina
FT [5], CLIPseq [6]"
FT miRNA 58..78
FT /accession="MIMAT0015106"
FT /product="cel-miR-65-3p"
FT /evidence=experimental
FT /experiment="CLIPseq [6]"
XX
SQ Sequence 100 BP; 24 A; 27 C; 24 G; 0 T; 25 other;
auggagccuu cgccgauuau gacacugaag cguaaccgaa caccauauuu ugagauucug 60
cuacgcgcag ugccaugcuc ggcgcguugg cuccauuaaa 100
//
ID cel-mir-66 standard; RNA; CEL; 99 BP.
XX
AC MI0000037;
XX
DE Caenorhabditis elegans miR-66 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; Y48G9A/93240-93338; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 17..39
FT /accession="MIMAT0000038"
FT /product="cel-miR-66-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1], 454 [3], Illumina
FT [4-5]"
FT miRNA 60..80
FT /accession="MIMAT0020315"
FT /product="cel-miR-66-3p"
FT /evidence=experimental
FT /experiment="Illumina [5]"
XX
SQ Sequence 99 BP; 32 A; 18 C; 23 G; 0 T; 26 other;
ccacaaaaau gccauacaug acacugauua gggaugugau gaauguuaag aucccgauca 60
aauuccuaac ggugucaaac auggcguaug ugguuguag 99
//
ID cel-mir-67 standard; RNA; CEL; 99 BP.
XX
AC MI0000038;
XX
DE Caenorhabditis elegans miR-67 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [6]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; EGAP1/4494-4396; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 20..42
FT /accession="MIMAT0020316"
FT /product="cel-miR-67-5p"
FT /evidence=experimental
FT /experiment="Illumina [6]"
FT miRNA 61..84
FT /accession="MIMAT0000039"
FT /product="cel-miR-67-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], 454 [3], Illumina [4,6],
FT CLIPseq [5]"
XX
SQ Sequence 99 BP; 30 A; 21 C; 17 G; 0 T; 31 other;
gaucaaagau ucgucgaucc gcucauucug ccgguuguua ugcuauuauc agauuaagca 60
ucacaaccuc cuagaaagag uagaucgauu uuaaaacuu 99
//
ID cel-mir-70 standard; RNA; CEL; 100 BP.
XX
AC MI0000041;
XX
DE Caenorhabditis elegans miR-70 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [5]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [6]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [7]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; T10H9/32413-32314; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 25..47
FT /accession="MIMAT0020317"
FT /product="cel-miR-70-5p"
FT /evidence=experimental
FT /experiment="Illumina [7]"
FT miRNA 62..84
FT /accession="MIMAT0000042"
FT /product="cel-miR-70-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], 454 [4], Illumina [5,7],
FT CLIPseq [6]"
XX
SQ Sequence 100 BP; 39 A; 13 C; 16 G; 0 T; 32 other;
ucaaaauaaa acgaugaaaa cuaucgaaau acuaucgacg aauaacacuu augaagaaau 60
guaauacguc guugguguuu ccauaguuug aauuguuuau 100
//
ID cel-mir-71 standard; RNA; CEL; 94 BP.
XX
AC MI0000042;
XX
DE Caenorhabditis elegans miR-71 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [5]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [6]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [7]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; F16A11/5547-5454; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..38
FT /accession="MIMAT0000043"
FT /product="cel-miR-71-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3], 454 [4], Illumina [5,7],
FT CLIPseq [6]"
FT miRNA 53..73
FT /accession="MIMAT0015107"
FT /product="cel-miR-71-3p"
FT /evidence=experimental
FT /experiment="CLIPseq [6], Illumina [7]"
XX
SQ Sequence 94 BP; 19 A; 21 C; 28 G; 0 T; 26 other;
gucugcucug aacgaugaaa gacaugggua gugagacguc ggagccucgu cguaucacua 60
uucuguuuuu cgccgucggg aucgugaccu ggaa 94
//
ID cel-mir-72 standard; RNA; CEL; 99 BP.
XX
AC MI0000043;
XX
DE Caenorhabditis elegans miR-72 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 11679672.
RA Lee RC, Ambros V;
RT "An extensive class of small RNAs in Caenorhabditis elegans";
RL Science. 294:862-864(2001).
XX
RN [3]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [4]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [5]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [6]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [7]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [8]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; F53G2/2401-2495; .
XX
CC The expression of C. elegans miR-72 was confirmed by PCR amplification,
CC cloning and sequencing. The predicted hairpin precursor sequence presented
CC here is supported by conservation in C. elegans and C. briggsae
CC (MIR:MI0000751), and differs from that shown in [1] (Uwe Ohler, pers.
CC comm.). The extents of the dominant mature miRNA species are adjusted
CC here in accordance with a large scale cloning and sequencing study [5].
XX
FH Key Location/Qualifiers
FH
FT miRNA 17..39
FT /accession="MIMAT0000044"
FT /product="cel-miR-72-5p"
FT /evidence=experimental
FT /experiment="cloned [1-4], 454 [5], Illumina [6,8],
FT CLIPseq [7]"
FT miRNA 61..82
FT /accession="MIMAT0020318"
FT /product="cel-miR-72-3p"
FT /evidence=experimental
FT /experiment="Illumina [8]"
XX
SQ Sequence 99 BP; 26 A; 26 C; 24 G; 0 T; 23 other;
aggucccguc agagcuaggc aagauguugg cauagcugaa ugaucgcuau aacaacuauc 60
agcuucgcca cauucugcca cgcacugaug ugaggaccu 99
//
ID cel-mir-73 standard; RNA; CEL; 99 BP.
XX
AC MI0000044;
XX
DE Caenorhabditis elegans miR-73 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [5]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [6]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [7]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; T24D8/30624-30722; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 23..46
FT /accession="MIMAT0020319"
FT /product="cel-miR-73-5p"
FT /evidence=experimental
FT /experiment="Illumina [7]"
FT miRNA 62..84
FT /accession="MIMAT0000045"
FT /product="cel-miR-73-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], 454 [4], Illumina [5,7],
FT CLIPseq [6]"
XX
SQ Sequence 99 BP; 26 A; 23 C; 26 G; 0 T; 24 other;
cagugagagu cccacacacg acuggacuuc cauaucgagc cacagcuauc aacgaauuug 60
cuggcaagau guaggcaguu caguugugcg uuuauggag 99
//
ID cel-mir-74 standard; RNA; CEL; 97 BP.
XX
AC MI0000045;
XX
DE Caenorhabditis elegans miR-74 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [5]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [6]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [7]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; T24D8/30902-30998; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 20..42
FT /accession="MIMAT0020320"
FT /product="cel-miR-74-5p"
FT /evidence=experimental
FT /experiment="Illumina [7]"
FT miRNA 61..82
FT /accession="MIMAT0000046"
FT /product="cel-miR-74-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], 454 [4], Illumina [5,7],
FT CLIPseq [6]"
XX
SQ Sequence 97 BP; 28 A; 27 C; 17 G; 0 T; 25 other;
aaaugguuca aaaaacguuc gggcuuccau cucuuuccca gccuacaucu caaccugggc 60
uggcaagaaa uggcagucua cacguuuuuc aaccaaa 97
//
ID cel-mir-75 standard; RNA; CEL; 97 BP.
XX
AC MI0000046;
XX
DE Caenorhabditis elegans miR-75 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [6]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; T24D8/34313-34409; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 23..44
FT /accession="MIMAT0015108"
FT /product="cel-miR-75-5p"
FT /evidence=experimental
FT /experiment="CLIPseq [5], Illumina [6]"
FT miRNA 61..82
FT /accession="MIMAT0000047"
FT /product="cel-miR-75-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], 454 [3], Illumina [4,6],
FT CLIPseq [5]"
XX
SQ Sequence 97 BP; 30 A; 18 C; 20 G; 0 T; 29 other;
uucuuguugc uuugaagaau ugcagucggu ugcaagcuua aauacaaauc cgaauuguua 60
uuaaagcuac caaccggcuu caagucugaa agagcag 97
//
ID cel-mir-76 standard; RNA; CEL; 97 BP.
XX
AC MI0000047;
XX
DE Caenorhabditis elegans miR-76 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [6]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; C44B11/10451-10547; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..37
FT /accession="MIMAT0020321"
FT /product="cel-miR-76-5p"
FT /evidence=experimental
FT /experiment="Illumina [6]"
FT miRNA 61..82
FT /accession="MIMAT0000048"
FT /product="cel-miR-76-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], 454 [3], Illumina [4,6],
FT CLIPseq [5]"
XX
SQ Sequence 97 BP; 27 A; 15 C; 23 G; 0 T; 32 other;
auuucagcuc cugucugggc uucacaauag ucgaauaccu uaaauuucaa aauuuggaua 60
uucguuguug augaagccuu gaugggggug agaaaga 97
//
ID cel-mir-77 standard; RNA; CEL; 100 BP.
XX
AC MI0000048;
XX
DE Caenorhabditis elegans miR-77 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [6]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; T21B4/29149-29248; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 24..45
FT /accession="MIMAT0020774"
FT /product="cel-miR-77-5p"
FT /evidence=experimental
FT /experiment="Illumina [6]"
FT miRNA 62..83
FT /accession="MIMAT0000049"
FT /product="cel-miR-77-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], 454 [3], Illumina [4,6],
FT CLIPseq [5]"
XX
SQ Sequence 100 BP; 25 A; 22 C; 25 G; 0 T; 28 other;
gcaucugcca aaccgcccgu uuggaugguu gugcucugag gaaauacgca cagaauguca 60
uuucaucagg ccauagcugu ccaaauuggu auagaguuug 100
//
ID cel-mir-78 standard; RNA; CEL; 96 BP.
XX
AC MI0000049;
XX
DE Caenorhabditis elegans miR-78 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
DR WORMBASE; Y40H7A/25290-25385; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 61..81
FT /accession="MIMAT0000050"
FT /product="cel-miR-78"
FT /evidence=experimental
FT /experiment="cloned [1-2], 454 [3], Illumina [4]"
XX
SQ Sequence 96 BP; 30 A; 9 C; 20 G; 0 T; 37 other;
aauaaaauau auuguuucau aguguccgua aaauaacuag auuuauuuug uaaaaacuau 60
uggaggccug guuguuugug cuggaauguu ucgaga 96
//
ID cel-mir-79 standard; RNA; CEL; 98 BP.
XX
AC MI0000050;
XX
DE Caenorhabditis elegans miR-79 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 12769849.
RA Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J;
RT "Computational and experimental identification of C. elegans microRNAs";
RL Mol Cell. 11:1253-1263(2003).
XX
RN [5]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [6]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [7]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [8]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; C12C8/13303-13400; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 19..41
FT /accession="MIMAT0020322"
FT /product="cel-miR-79-5p"
FT /evidence=experimental
FT /experiment="Illumina [8]"
FT miRNA 61..82
FT /accession="MIMAT0000051"
FT /product="cel-miR-79-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], PCR [4], 454 [5], Illumina
FT [6,8], CLIPseq [7]"
XX
SQ Sequence 98 BP; 23 A; 21 C; 20 G; 0 T; 34 other;
uaguagacau ucuccgaucu uuggugauuc agcuucaaug auuggcuaca gguuucuuuc 60
auaaagcuag guuaccaaag cucggcgucu ugaucuac 98
//
ID cel-mir-80 standard; RNA; CEL; 98 BP.
XX
AC MI0000051;
XX
DE Caenorhabditis elegans miR-80/miR-227 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 11679672.
RA Lee RC, Ambros V;
RT "An extensive class of small RNAs in Caenorhabditis elegans";
RL Science. 294:862-864(2001).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [5]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [6]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [7]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR WORMBASE; K01F9/1056-959; .
XX
CC mir-80 is conserved in C.briggsae (MIR:MI0000518) [1]. Reference [3]
CC reports the identification of miR-227, which appears to be expressed from
CC the 5' arm of the same precursor.
XX
FH Key Location/Qualifiers
FH
FT miRNA 19..40
FT /accession="MIMAT0000052"
FT /product="cel-miR-80-5p"
FT /evidence=experimental
FT /experiment="cloned [3], Illumina [6], CLIPseq [7]"
FT miRNA 61..83
FT /accession="MIMAT0000053"
FT /product="cel-miR-80-3p"
FT /evidence=experimental
FT /experiment="cloned [1-4], Northern [1], 454 [5], Illumina
FT [6], CLIPseq [7]"
XX
SQ Sequence 98 BP; 28 A; 22 C; 21 G; 0 T; 27 other;
auggacacuc guucgcucag cuuucgacau gauucugaac aauccgcaag cccauguugu 60
ugagaucauu aguugaaagc cgaaugauca gagauauc 98
//
ID cel-mir-81 standard; RNA; CEL; 108 BP.
XX
AC MI0000052;
XX
DE Caenorhabditis elegans miR-81 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 11679672.
RA Lee RC, Ambros V;
RT "An extensive class of small RNAs in Caenorhabditis elegans";
RL Science. 294:862-864(2001).
XX
RN [3]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [4]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [5]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [6]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [7]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR WORMBASE; T07D1/14195-14302; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 25..46
FT /accession="MIMAT0015109"
FT /product="cel-miR-81-5p"
FT /evidence=experimental
FT /experiment="CLIPseq [7]"
FT miRNA 67..88
FT /accession="MIMAT0000054"
FT /product="cel-miR-81-3p"
FT /evidence=experimental
FT /experiment="cloned [1-4], 454 [5], Illumina [6], CLIPseq
FT [7]"
XX
SQ Sequence 108 BP; 25 A; 24 C; 26 G; 0 T; 33 other;
aucagugcca ucgugcccaa cagucgguuu ucaccgugau cugagagcaa uccaaaaaug 60
cuuuucugag aucaucguga aagcuaguug uuggucuacg ggcuuuug 108
//
ID cel-mir-82 standard; RNA; CEL; 97 BP.
XX
AC MI0000053;
XX
DE Caenorhabditis elegans miR-82 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [6]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; T07D1/18477-18381; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 22..44
FT /accession="MIMAT0020323"
FT /product="cel-miR-82-5p"
FT /evidence=experimental
FT /experiment="Illumina [6]"
FT miRNA 61..82
FT /accession="MIMAT0000055"
FT /product="cel-miR-82-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], 454 [3], Illumina [4,6],
FT CLIPseq [5]"
XX
SQ Sequence 97 BP; 26 A; 18 C; 20 G; 0 T; 33 other;
gaaauagguu cuuuuagcaa ccgguuuucu cugugaucua cagaaugaca gcuaaucguc 60
ugagaucauc gugaaagcca guuguuuuua ugaacuc 97
//
ID cel-mir-83 standard; RNA; CEL; 98 BP.
XX
AC MI0000054;
XX
DE Caenorhabditis elegans miR-83 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [5]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [6]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [7]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; C06A6/16005-16102; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 17..39
FT /accession="MIMAT0020775"
FT /product="cel-miR-83-5p"
FT /evidence=experimental
FT /experiment="Illumina [7]"
FT miRNA 61..82
FT /accession="MIMAT0000056"
FT /product="cel-miR-83-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], 454 [4], Illumina [5,7],
FT CLIPseq [6]"
XX
SQ Sequence 98 BP; 30 A; 24 C; 20 G; 0 T; 24 other;
agcaccacuc ggaaccacug aauuuaugug uguacuugac ggccaacaag agcaucgauc 60
uagcaccaua uaaauucagu aauuucgcgu cgagagcu 98
//
ID cel-mir-84 standard; RNA; CEL; 75 BP.
XX
AC MI0000055;
XX
DE Caenorhabditis elegans miR-84 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [5]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [6]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [7]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; B0395/3359-3285; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 9..32
FT /accession="MIMAT0000057"
FT /product="cel-miR-84-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Northern [1], 454 [4], Illumina
FT [5,7], CLIPseq [6]"
FT miRNA 47..69
FT /accession="MIMAT0015110"
FT /product="cel-miR-84-3p"
FT /evidence=experimental
FT /experiment="CLIPseq [6], Illumina [7]"
XX
SQ Sequence 75 BP; 19 A; 13 C; 16 G; 0 T; 27 other;
guggcaucug agguaguaug uaauauugua gacugucuau aauguccaca auguuucaac 60
uaacucggcu guucu 75
//
ID cel-mir-85 standard; RNA; CEL; 106 BP.
XX
AC MI0000056;
XX
DE Caenorhabditis elegans miR-85 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [5]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [6]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [7]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; F49E12/16076-16181; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 23..45
FT /accession="MIMAT0020324"
FT /product="cel-miR-85-5p"
FT /evidence=experimental
FT /experiment="Illumina [7]"
FT miRNA 65..88
FT /accession="MIMAT0000058"
FT /product="cel-miR-85-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], 454 [4], Illumina [5,7],
FT CLIPseq [6]"
XX
SQ Sequence 106 BP; 35 A; 15 C; 21 G; 0 T; 35 other;
uauagaauuu uggcgucgga gcccgauuuu ucaauaguuu gaaaccagug uacacauaaa 60
ugguuacaaa guauuugaaa agucgugcuc ugaaaaugaa uucuua 106
//
ID cel-mir-86 standard; RNA; CEL; 98 BP.
XX
AC MI0000057;
XX
DE Caenorhabditis elegans miR-86 stem-loop
XX
RN [1]
RX PUBMED; 11679671.
RA Lau NC, Lim LP, Weinstein EG, Bartel DP;
RT "An abundant class of tiny RNAs with probable regulatory roles in
RT Caenorhabditis elegans";
RL Science. 294:858-862(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [5]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [6]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [7]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; Y56A3A/102935-102838; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..38
FT /accession="MIMAT0000059"
FT /product="cel-miR-86-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3], 454 [4], Illumina [5,7],
FT CLIPseq [6]"
FT miRNA 60..81
FT /accession="MIMAT0020776"
FT /product="cel-miR-86-3p"
FT /evidence=experimental
FT /experiment="Illumina [7]"
XX
SQ Sequence 98 BP; 20 A; 25 C; 27 G; 0 T; 26 other;
cguguccacg ccgucuaagu gaaugcuuug ccacagucuu cgauguucug aaaugaagcc 60
ugggcucaga uucgcuuagg ccggaguuug acacggca 98
//
ID cel-mir-87 standard; RNA; CEL; 94 BP.
XX
AC MI0000058;
XX
DE Caenorhabditis elegans miR-87 stem-loop
XX
RN [1]
RX PUBMED; 11679672.
RA Lee RC, Ambros V;
RT "An extensive class of small RNAs in Caenorhabditis elegans";
RL Science. 294:862-864(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [5]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [6]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [7]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; F10C2/16068-15975; .
XX
CC mir-87 is has found to be most abundant in the L1 stage of larval
CC development in Caenorhabditis elegans. mir-87 orthologues have been found
CC in C. briggsae, Drosophila melanogaster and humans [1]. The extents of
CC the dominant mature miRNA species are adjusted here in accordance with a
CC large scale cloning and sequencing study [4].
XX
FH Key Location/Qualifiers
FH
FT miRNA 17..40
FT /accession="MIMAT0020325"
FT /product="cel-miR-87-5p"
FT /evidence=experimental
FT /experiment="Illumina [7]"
FT miRNA 61..82
FT /accession="MIMAT0000060"
FT /product="cel-miR-87-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], 454 [4], Illumina [5,7],
FT CLIPseq [6]"
XX
SQ Sequence 94 BP; 17 A; 27 C; 26 G; 0 T; 24 other;
gguugugcca uccggccgcc ugauacuuuc gucucaaccu cgcugucaga uuggucguag 60
gugagcaaag uuucaggugu gccggaacac accc 94
//
ID cel-mir-90 standard; RNA; CEL; 98 BP.
XX
AC MI0000059;
XX
DE Caenorhabditis elegans miR-90 stem-loop
XX
RN [1]
RX PUBMED; 11679672.
RA Lee RC, Ambros V;
RT "An extensive class of small RNAs in Caenorhabditis elegans";
RL Science. 294:862-864(2001).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [3]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [4]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [5]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [6]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [7]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; K01F9/9773-9676; .
XX
CC mir-90 is has found to be most abundant in the L1 stage of larval
CC development in Caenorhabditis elegans [1]. The extents of the dominant
CC mature miRNA species are adjusted here in accordance with a large scale
CC cloning and sequencing study [4].
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..38
FT /accession="MIMAT0020326"
FT /product="cel-miR-90-5p"
FT /evidence=experimental
FT /experiment="Illumina [7]"
FT miRNA 62..84
FT /accession="MIMAT0000061"
FT /product="cel-miR-90-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], 454 [4], Illumina [5,7],
FT CLIPseq [6]"
XX
SQ Sequence 98 BP; 22 A; 24 C; 23 G; 0 T; 29 other;
gggcgccauu ucgagcggcu uucaacgacg auaucaaccg acaacucaca cuuuugcgug 60
uugauauguu guuugaaugc cccuugaauu ggaugcca 98
//
ID hsa-let-7a-1 standard; RNA; HSA; 80 BP.
XX
AC MI0000060;
XX
DE Homo sapiens let-7a-1 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 15183728.
RA Suh MR, Lee Y, Kim JY, Kim SK, Moon SH, Lee JY, Cha KY, Chung HM, Yoon HS,
RA Moon SY, Kim VN, Kim KS;
RT "Human embryonic stem cells express a unique set of microRNAs";
RL Dev Biol. 270:488-498(2004).
XX
RN [3]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
XX
RN [4]
RX PUBMED; 14573789.
RA Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ;
RT "Reduced accumulation of specific microRNAs in colorectal neoplasia";
RL Mol Cancer Res. 1:882-891(2003).
XX
RN [5]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [6]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [7]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
RN [8]
RX PUBMED; 17989717.
RA Marton S, Garcia MR, Robello C, Persson H, Trajtenberg F, Pritsch O,
RA Rovira C, Naya H, Dighiero G, Cayota A;
RT "Small RNAs analysis in CLL reveals a deregulation of miRNA expression and
RT novel miRNA candidates of putative relevance in CLL pathogenesis";
RL Leukemia. 22:330-338(2008).
XX
RN [9]
RX PUBMED; 20158877.
RA Koh W, Sheng CT, Tan B, Lee QY, Kuznetsov V, Kiang LS, Tanavde V;
RT "Analysis of deep sequencing microRNA expression profile from human
RT embryonic stem cells derived mesenchymal stem cells reveals possible role
RT of let-7 microRNA family in downstream targeting of hepatic nuclear factor
RT 4 alpha";
RL BMC Genomics. 11 Suppl 1:S6(2010).
XX
DR RFAM; RF00027; let-7.
DR TARGETS:PICTAR-VERT; hsa-let-7a; hsa-let-7a.
DR HGNC; 31476; MIRLET7A1.
DR ENTREZGENE; 406881; MIRLET7A1.
XX
CC let-7a-3p cloned in [6] has a 1 nt 3' extension (U), which is incompatible
CC with the genome sequence.
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..27
FT /accession="MIMAT0000062"
FT /product="hsa-let-7a-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3,5-8], Northern [1], Illumina [9]"
FT miRNA 57..77
FT /accession="MIMAT0004481"
FT /product="hsa-let-7a-3p"
FT /evidence=experimental
FT /experiment="cloned [6]"
XX
SQ Sequence 80 BP; 21 A; 15 C; 19 G; 0 T; 25 other;
ugggaugagg uaguagguug uauaguuuua gggucacacc caccacuggg agauaacuau 60
acaaucuacu gucuuuccua 80
//
ID hsa-let-7a-2 standard; RNA; HSA; 72 BP.
XX
AC MI0000061;
XX
DE Homo sapiens let-7a-2 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 15183728.
RA Suh MR, Lee Y, Kim JY, Kim SK, Moon SH, Lee JY, Cha KY, Chung HM, Yoon HS,
RA Moon SY, Kim VN, Kim KS;
RT "Human embryonic stem cells express a unique set of microRNAs";
RL Dev Biol. 270:488-498(2004).
XX
RN [3]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
XX
RN [4]
RX PUBMED; 14573789.
RA Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ;
RT "Reduced accumulation of specific microRNAs in colorectal neoplasia";
RL Mol Cancer Res. 1:882-891(2003).
XX
RN [5]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [6]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [7]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
RN [8]
RX PUBMED; 17989717.
RA Marton S, Garcia MR, Robello C, Persson H, Trajtenberg F, Pritsch O,
RA Rovira C, Naya H, Dighiero G, Cayota A;
RT "Small RNAs analysis in CLL reveals a deregulation of miRNA expression and
RT novel miRNA candidates of putative relevance in CLL pathogenesis";
RL Leukemia. 22:330-338(2008).
XX
RN [9]
RX PUBMED; 19015728.
RA Tzur G, Levy A, Meiri E, Barad O, Spector Y, Bentwich Z, Mizrahi L,
RA Katzenellenbogen M, Ben-Shushan E, Reubinoff BE, Galun E;
RT "MicroRNA expression patterns and function in endodermal differentiation
RT of human embryonic stem cells";
RL PLoS One. 3:e3726(2008).
XX
RN [10]
RX PUBMED; 20158877.
RA Koh W, Sheng CT, Tan B, Lee QY, Kuznetsov V, Kiang LS, Tanavde V;
RT "Analysis of deep sequencing microRNA expression profile from human
RT embryonic stem cells derived mesenchymal stem cells reveals possible role
RT of let-7 microRNA family in downstream targeting of hepatic nuclear factor
RT 4 alpha";
RL BMC Genomics. 11 Suppl 1:S6(2010).
XX
DR RFAM; RF00027; let-7.
DR TARGETS:PICTAR-VERT; hsa-let-7a; hsa-let-7a.
DR HGNC; 31477; MIRLET7A2.
DR ENTREZGENE; 406882; MIRLET7A2.
XX
FH Key Location/Qualifiers
FH
FT miRNA 5..26
FT /accession="MIMAT0000062"
FT /product="hsa-let-7a-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3,5-8], Northern [1], Illumina
FT [10]"
FT miRNA 50..71
FT /accession="MIMAT0010195"
FT /product="hsa-let-7a-2-3p"
FT /evidence=experimental
FT /experiment="qRT-PCR [9]"
XX
SQ Sequence 72 BP; 20 A; 11 C; 18 G; 0 T; 23 other;
agguugaggu aguagguugu auaguuuaga auuacaucaa gggagauaac uguacagccu 60
ccuagcuuuc cu 72
//
ID hsa-let-7a-3 standard; RNA; HSA; 74 BP.
XX
AC MI0000062;
XX
DE Homo sapiens let-7a-3 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 15183728.
RA Suh MR, Lee Y, Kim JY, Kim SK, Moon SH, Lee JY, Cha KY, Chung HM, Yoon HS,
RA Moon SY, Kim VN, Kim KS;
RT "Human embryonic stem cells express a unique set of microRNAs";
RL Dev Biol. 270:488-498(2004).
XX
RN [3]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
XX
RN [4]
RX PUBMED; 14573789.
RA Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ;
RT "Reduced accumulation of specific microRNAs in colorectal neoplasia";
RL Mol Cancer Res. 1:882-891(2003).
XX
RN [5]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [6]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [7]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
RN [8]
RX PUBMED; 17989717.
RA Marton S, Garcia MR, Robello C, Persson H, Trajtenberg F, Pritsch O,
RA Rovira C, Naya H, Dighiero G, Cayota A;
RT "Small RNAs analysis in CLL reveals a deregulation of miRNA expression and
RT novel miRNA candidates of putative relevance in CLL pathogenesis";
RL Leukemia. 22:330-338(2008).
XX
RN [9]
RX PUBMED; 20158877.
RA Koh W, Sheng CT, Tan B, Lee QY, Kuznetsov V, Kiang LS, Tanavde V;
RT "Analysis of deep sequencing microRNA expression profile from human
RT embryonic stem cells derived mesenchymal stem cells reveals possible role
RT of let-7 microRNA family in downstream targeting of hepatic nuclear factor
RT 4 alpha";
RL BMC Genomics. 11 Suppl 1:S6(2010).
XX
DR RFAM; RF00027; let-7.
DR TARGETS:PICTAR-VERT; hsa-let-7a; hsa-let-7a.
DR HGNC; 31478; MIRLET7A3.
DR ENTREZGENE; 406883; MIRLET7A3.
XX
CC let-7a-3p cloned in [6] has a 1 nt 3' extension (U), which is incompatible
CC with the genome sequence.
XX
FH Key Location/Qualifiers
FH
FT miRNA 4..25
FT /accession="MIMAT0000062"
FT /product="hsa-let-7a-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3,5-8], Northern [1], Illumina [9]"
FT miRNA 52..72
FT /accession="MIMAT0004481"
FT /product="hsa-let-7a-3p"
FT /evidence=experimental
FT /experiment="cloned [6]"
XX
SQ Sequence 74 BP; 14 A; 13 C; 21 G; 0 T; 26 other;
gggugaggua guagguugua uaguuugggg cucugcccug cuaugggaua acuauacaau 60
cuacugucuu uccu 74
//
ID hsa-let-7b standard; RNA; HSA; 83 BP.
XX
AC MI0000063;
XX
DE Homo sapiens let-7b stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 14573789.
RA Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ;
RT "Reduced accumulation of specific microRNAs in colorectal neoplasia";
RL Mol Cancer Res. 1:882-891(2003).
XX
RN [3]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR RFAM; RF00027; let-7.
DR TARGETS:PICTAR-VERT; hsa-let-7b; hsa-let-7b.
DR HGNC; 31479; MIRLET7B.
DR ENTREZGENE; 406884; MIRLET7B.
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..27
FT /accession="MIMAT0000063"
FT /product="hsa-let-7b-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3-5], Northern [1]"
FT miRNA 60..81
FT /accession="MIMAT0004482"
FT /product="hsa-let-7b-3p"
FT /evidence=experimental
FT /experiment="cloned [4-5]"
XX
SQ Sequence 83 BP; 16 A; 18 C; 26 G; 0 T; 23 other;
cggggugagg uaguagguug ugugguuuca gggcagugau guugccccuc ggaagauaac 60
uauacaaccu acugccuucc cug 83
//
ID hsa-let-7c standard; RNA; HSA; 84 BP.
XX
AC MI0000064;
XX
DE Homo sapiens let-7c stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 14573789.
RA Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ;
RT "Reduced accumulation of specific microRNAs in colorectal neoplasia";
RL Mol Cancer Res. 1:882-891(2003).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
RN [5]
RX PUBMED; 20158877.
RA Koh W, Sheng CT, Tan B, Lee QY, Kuznetsov V, Kiang LS, Tanavde V;
RT "Analysis of deep sequencing microRNA expression profile from human
RT embryonic stem cells derived mesenchymal stem cells reveals possible role
RT of let-7 microRNA family in downstream targeting of hepatic nuclear factor
RT 4 alpha";
RL BMC Genomics. 11 Suppl 1:S6(2010).
XX
RN [6]
RX PUBMED; 23034410.
RA Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H,
RA Khaitovich P, Kaessmann H;
RT "Birth and expression evolution of mammalian microRNA genes";
RL Genome Res. 23:34-45(2013).
XX
DR RFAM; RF00027; let-7.
DR TARGETS:PICTAR-VERT; hsa-let-7c; hsa-let-7c.
DR HGNC; 31480; MIRLET7C.
DR ENTREZGENE; 406885; MIRLET7C.
XX
FH Key Location/Qualifiers
FH
FT miRNA 11..32
FT /accession="MIMAT0000064"
FT /product="hsa-let-7c-5p"
FT /evidence=experimental
FT /experiment="cloned [1-4], Northern [1], Illumina [5-6]"
FT miRNA 56..77
FT /accession="MIMAT0026472"
FT /product="hsa-let-7c-3p"
FT /evidence=experimental
FT /experiment="Illumina [6]"
XX
SQ Sequence 84 BP; 17 A; 16 C; 24 G; 0 T; 27 other;
gcauccgggu ugagguagua gguuguaugg uuuagaguua cacccuggga guuaacugua 60
caaccuucua gcuuuccuug gagc 84
//
ID hsa-let-7d standard; RNA; HSA; 87 BP.
XX
AC MI0000065;
XX
DE Homo sapiens let-7d stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
RN [5]
RX PUBMED; 20158877.
RA Koh W, Sheng CT, Tan B, Lee QY, Kuznetsov V, Kiang LS, Tanavde V;
RT "Analysis of deep sequencing microRNA expression profile from human
RT embryonic stem cells derived mesenchymal stem cells reveals possible role
RT of let-7 microRNA family in downstream targeting of hepatic nuclear factor
RT 4 alpha";
RL BMC Genomics. 11 Suppl 1:S6(2010).
XX
DR RFAM; RF00027; let-7.
DR TARGETS:PICTAR-VERT; hsa-let-7d; hsa-let-7d.
DR HGNC; 31481; MIRLET7D.
DR ENTREZGENE; 406886; MIRLET7D.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 8..29
FT /accession="MIMAT0000065"
FT /product="hsa-let-7d-5p"
FT /evidence=experimental
FT /experiment="cloned [1-4], Northern [1], Illumina [5]"
FT miRNA 62..83
FT /accession="MIMAT0004484"
FT /product="hsa-let-7d-3p"
FT /evidence=experimental
FT /experiment="cloned [3]"
XX
SQ Sequence 87 BP; 21 A; 16 C; 26 G; 0 T; 24 other;
ccuaggaaga gguaguaggu ugcauaguuu uagggcaggg auuuugccca caaggaggua 60
acuauacgac cugcugccuu ucuuagg 87
//
ID hsa-let-7e standard; RNA; HSA; 79 BP.
XX
AC MI0000066;
XX
DE Homo sapiens let-7e stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
RN [5]
RX PUBMED; 20158877.
RA Koh W, Sheng CT, Tan B, Lee QY, Kuznetsov V, Kiang LS, Tanavde V;
RT "Analysis of deep sequencing microRNA expression profile from human
RT embryonic stem cells derived mesenchymal stem cells reveals possible role
RT of let-7 microRNA family in downstream targeting of hepatic nuclear factor
RT 4 alpha";
RL BMC Genomics. 11 Suppl 1:S6(2010).
XX
DR RFAM; RF00027; let-7.
DR TARGETS:PICTAR-VERT; hsa-let-7e; hsa-let-7e.
DR HGNC; 31482; MIRLET7E.
DR ENTREZGENE; 406887; MIRLET7E.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 8..29
FT /accession="MIMAT0000066"
FT /product="hsa-let-7e-5p"
FT /evidence=experimental
FT /experiment="cloned [1-4], Northern [1], Illumina [5]"
FT miRNA 53..74
FT /accession="MIMAT0004485"
FT /product="hsa-let-7e-3p"
FT /evidence=experimental
FT /experiment="cloned [3]"
XX
SQ Sequence 79 BP; 18 A; 20 C; 25 G; 0 T; 16 other;
cccgggcuga gguaggaggu uguauaguug aggaggacac ccaaggagau cacuauacgg 60
ccuccuagcu uuccccagg 79
//
ID hsa-let-7f-1 standard; RNA; HSA; 87 BP.
XX
AC MI0000067;
XX
DE Homo sapiens let-7f-1 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 14573789.
RA Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ;
RT "Reduced accumulation of specific microRNAs in colorectal neoplasia";
RL Mol Cancer Res. 1:882-891(2003).
XX
RN [3]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
RN [6]
RX PUBMED; 20158877.
RA Koh W, Sheng CT, Tan B, Lee QY, Kuznetsov V, Kiang LS, Tanavde V;
RT "Analysis of deep sequencing microRNA expression profile from human
RT embryonic stem cells derived mesenchymal stem cells reveals possible role
RT of let-7 microRNA family in downstream targeting of hepatic nuclear factor
RT 4 alpha";
RL BMC Genomics. 11 Suppl 1:S6(2010).
XX
DR RFAM; RF00027; let-7.
DR TARGETS:PICTAR-VERT; hsa-let-7f; hsa-let-7f.
DR HGNC; 31483; MIRLET7F1.
DR ENTREZGENE; 406888; MIRLET7F1.
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..28
FT /accession="MIMAT0000067"
FT /product="hsa-let-7f-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3-5], Northern [1], Illumina [6]"
FT miRNA 63..84
FT /accession="MIMAT0004486"
FT /product="hsa-let-7f-1-3p"
FT /evidence=experimental
FT /experiment="cloned [4]"
XX
SQ Sequence 87 BP; 22 A; 13 C; 22 G; 0 T; 30 other;
ucagagugag guaguagauu guauaguugu gggguaguga uuuuacccug uucaggagau 60
aacuauacaa ucuauugccu ucccuga 87
//
ID hsa-let-7f-2 standard; RNA; HSA; 83 BP.
XX
AC MI0000068;
XX
DE Homo sapiens let-7f-2 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 14573789.
RA Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ;
RT "Reduced accumulation of specific microRNAs in colorectal neoplasia";
RL Mol Cancer Res. 1:882-891(2003).
XX
RN [3]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
RN [6]
RX PUBMED; 20158877.
RA Koh W, Sheng CT, Tan B, Lee QY, Kuznetsov V, Kiang LS, Tanavde V;
RT "Analysis of deep sequencing microRNA expression profile from human
RT embryonic stem cells derived mesenchymal stem cells reveals possible role
RT of let-7 microRNA family in downstream targeting of hepatic nuclear factor
RT 4 alpha";
RL BMC Genomics. 11 Suppl 1:S6(2010).
XX
DR RFAM; RF00027; let-7.
DR TARGETS:PICTAR-VERT; hsa-let-7f; hsa-let-7f.
DR HGNC; 31484; MIRLET7F2.
DR ENTREZGENE; 406889; MIRLET7F2.
XX
FH Key Location/Qualifiers
FH
FT miRNA 8..29
FT /accession="MIMAT0000067"
FT /product="hsa-let-7f-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3-5], Northern [1], Illumina [6]"
FT miRNA 58..79
FT /accession="MIMAT0004487"
FT /product="hsa-let-7f-2-3p"
FT /evidence=experimental
FT /experiment="cloned [4]"
XX
SQ Sequence 83 BP; 20 A; 15 C; 20 G; 0 T; 28 other;
ugugggauga gguaguagau uguauaguuu uagggucaua ccccaucuug gagauaacua 60
uacagucuac ugucuuuccc acg 83
//
ID hsa-mir-15a standard; RNA; HSA; 83 BP.
XX
AC MI0000069;
XX
DE Homo sapiens miR-15a stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 12434020.
RA Calin GA, Dumitru CD, Shimizu M, Bichi R, Zupo S, Noch E, Aldler H, Rattan
RA S, Keating M, Rai K, Rassenti L, Kipps T, Negrini M, Bullrich F, Croce CM;
RT "Frequent deletions and down-regulation of micro- RNA genes miR15 and
RT miR16 at 13q14 in chronic lymphocytic leukemia";
RL Proc Natl Acad Sci U S A. 99:15524-15529(2002).
XX
RN [3]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
XX
RN [4]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [5]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [6]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-15a; hsa-miR-15a.
DR HGNC; 31543; MIR15A.
DR ENTREZGENE; 406948; MIR15A.
XX
CC Reference [1] named this sequence miR-15. This is renamed miR-15a here to
CC avoid confusion with miR-15b (MIR:MI0000438) identified later by others.
CC This gene and miR-16 are clustered within 0.5 kb at 13q14. This region
CC has been shown to be deleted in more than half of B cell chronic
CC lymphocytic leukemias (CLL). Both miR-15a and miR-16 are deleted or
CC down-regulated in more than two thirds of CLL cases [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 14..35
FT /accession="MIMAT0000068"
FT /product="hsa-miR-15a-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3-6], Northern [1]"
FT miRNA 51..72
FT /accession="MIMAT0004488"
FT /product="hsa-miR-15a-3p"
FT /evidence=experimental
FT /experiment="cloned [5]"
XX
SQ Sequence 83 BP; 26 A; 13 C; 22 G; 0 T; 22 other;
ccuuggagua aaguagcagc acauaauggu uuguggauuu ugaaaaggug caggccauau 60
ugugcugccu caaaaauaca agg 83
//
ID hsa-mir-16-1 standard; RNA; HSA; 89 BP.
XX
AC MI0000070;
XX
DE Homo sapiens miR-16-1 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [3]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [4]
RX PUBMED; 12434020.
RA Calin GA, Dumitru CD, Shimizu M, Bichi R, Zupo S, Noch E, Aldler H, Rattan
RA S, Keating M, Rai K, Rassenti L, Kipps T, Negrini M, Bullrich F, Croce CM;
RT "Frequent deletions and down-regulation of micro- RNA genes miR15 and
RT miR16 at 13q14 in chronic lymphocytic leukemia";
RL Proc Natl Acad Sci U S A. 99:15524-15529(2002).
XX
RN [5]
RX PUBMED; 14573789.
RA Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ;
RT "Reduced accumulation of specific microRNAs in colorectal neoplasia";
RL Mol Cancer Res. 1:882-891(2003).
XX
RN [6]
RX PUBMED; 15183728.
RA Suh MR, Lee Y, Kim JY, Kim SK, Moon SH, Lee JY, Cha KY, Chung HM, Yoon HS,
RA Moon SY, Kim VN, Kim KS;
RT "Human embryonic stem cells express a unique set of microRNAs";
RL Dev Biol. 270:488-498(2004).
XX
RN [7]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [8]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [9]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-16; hsa-miR-16.
DR HGNC; 31545; MIR16-1.
DR ENTREZGENE; 406950; MIR16-1.
XX
CC Human miR-16 has been cloned by independent groups [1,2]. This precursor
CC sequence maps to chromosome 13, and was named mir-16 in [1] and
CC mir-16-precursor-13 in [2]. Lim et al. reported 2 identical chromosome 13
CC loci, which appear to map to the same locus in subsequent genome
CC assemblies. This gene and miR-15a are clustered within 0.5 kb at 13q14.
CC This region has been shown to be deleted in more than half of B cell
CC chronic lymphocytic leukemias (CLL). Both miR-15a and miR-16 are deleted
CC or down-regulated in more than two thirds of CLL cases [3]. A second
CC putative mir-16 hairpin precursor is located on chromosome 3
CC (MIR:MI0000738).
XX
FH Key Location/Qualifiers
FH
FT miRNA 14..35
FT /accession="MIMAT0000069"
FT /product="hsa-miR-16-5p"
FT /evidence=experimental
FT /experiment="cloned [1,5,7-9], Northern [1,6]"
FT miRNA 56..77
FT /accession="MIMAT0004489"
FT /product="hsa-miR-16-1-3p"
FT /evidence=experimental
FT /experiment="cloned [8]"
XX
SQ Sequence 89 BP; 26 A; 16 C; 20 G; 0 T; 27 other;
gucagcagug ccuuagcagc acguaaauau uggcguuaag auucuaaaau uaucuccagu 60
auuaacugug cugcugaagu aagguugac 89
//
ID hsa-mir-17 standard; RNA; HSA; 84 BP.
XX
AC MI0000071;
XX
DE Homo sapiens miR-17 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [3]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
XX
RN [4]
RX PUBMED; 15183728.
RA Suh MR, Lee Y, Kim JY, Kim SK, Moon SH, Lee JY, Cha KY, Chung HM, Yoon HS,
RA Moon SY, Kim VN, Kim KS;
RT "Human embryonic stem cells express a unique set of microRNAs";
RL Dev Biol. 270:488-498(2004).
XX
RN [5]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [6]
RX PUBMED; 15978578.
RA Fu H, Tie Y, Xu C, Zhang Z, Zhu J, Shi Y, Jiang H, Sun Z, Zheng X;
RT "Identification of human fetal liver miRNAs by a novel method";
RL FEBS Lett. 579:3849-3854(2005).
XX
RN [7]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [8]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR RFAM; RF00051; mir-17.
DR TARGETS:PICTAR-VERT; hsa-miR-17-3p; hsa-miR-17-3p.
DR TARGETS:PICTAR-VERT; hsa-miR-17-5p; hsa-miR-17-5p.
DR HGNC; 31547; MIR17.
DR ENTREZGENE; 406952; MIR17.
XX
FH Key Location/Qualifiers
FH
FT miRNA 14..36
FT /accession="MIMAT0000070"
FT /product="hsa-miR-17-5p"
FT /evidence=experimental
FT /experiment="cloned [2,5-8], Northern [4]"
FT miRNA 51..72
FT /accession="MIMAT0000071"
FT /product="hsa-miR-17-3p"
FT /evidence=experimental
FT /experiment="cloned [1,5,7-8], Northern [1]"
XX
SQ Sequence 84 BP; 24 A; 13 C; 23 G; 0 T; 24 other;
gucagaauaa ugucaaagug cuuacagugc agguagugau augugcaucu acugcaguga 60
aggcacuugu agcauuaugg ugac 84
//
ID hsa-mir-18a standard; RNA; HSA; 71 BP.
XX
AC MI0000072;
XX
DE Homo sapiens miR-18a stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [3]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [4]
RX PUBMED; 15978578.
RA Fu H, Tie Y, Xu C, Zhang Z, Zhu J, Shi Y, Jiang H, Sun Z, Zheng X;
RT "Identification of human fetal liver miRNAs by a novel method";
RL FEBS Lett. 579:3849-3854(2005).
XX
RN [5]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [6]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR HGNC; 31548; MIR18A.
DR ENTREZGENE; 406953; MIR18A.
XX
CC This sequence maps to chromosome 13 and is named miR-18 precursor-13 in
CC reference [2]. The mature sequence shown here represents the most
CC commonly cloned form from large-scale cloning studies [5]. The mature
CC sequence shown here represents the most commonly cloned form from
CC large-scale cloning studies [5].
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..28
FT /accession="MIMAT0000072"
FT /product="hsa-miR-18a-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3-6], Northern [1]"
FT miRNA 47..69
FT /accession="MIMAT0002891"
FT /product="hsa-miR-18a-3p"
FT /evidence=experimental
FT /experiment="cloned [4-6]"
XX
SQ Sequence 71 BP; 17 A; 15 C; 17 G; 0 T; 22 other;
uguucuaagg ugcaucuagu gcagauagug aaguagauua gcaucuacug cccuaagugc 60
uccuucuggc a 71
//
ID hsa-mir-19a standard; RNA; HSA; 82 BP.
XX
AC MI0000073;
XX
DE Homo sapiens miR-19a stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [3]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-19a; hsa-miR-19a.
DR HGNC; 31574; MIR19A.
DR ENTREZGENE; 406979; MIR19A.
XX
CC This sequence maps to chromosome 13 and is named miR-19a precursor-13 in
CC reference [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 14..35
FT /accession="MIMAT0004490"
FT /product="hsa-miR-19a-5p"
FT /evidence=experimental
FT /experiment="cloned [4]"
FT miRNA 49..71
FT /accession="MIMAT0000073"
FT /product="hsa-miR-19a-3p"
FT /evidence=experimental
FT /experiment="cloned [1-5], Northern [1]"
XX
SQ Sequence 82 BP; 22 A; 15 C; 20 G; 0 T; 25 other;
gcaguccucu guuaguuuug cauaguugca cuacaagaag aauguaguug ugcaaaucua 60
ugcaaaacug augguggccu gc 82
//
ID hsa-mir-19b-1 standard; RNA; HSA; 87 BP.
XX
AC MI0000074;
XX
DE Homo sapiens miR-19b-1 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [3]
RX PUBMED; 14573789.
RA Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ;
RT "Reduced accumulation of specific microRNAs in colorectal neoplasia";
RL Mol Cancer Res. 1:882-891(2003).
XX
RN [4]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
XX
RN [5]
RX PUBMED; 15183728.
RA Suh MR, Lee Y, Kim JY, Kim SK, Moon SH, Lee JY, Cha KY, Chung HM, Yoon HS,
RA Moon SY, Kim VN, Kim KS;
RT "Human embryonic stem cells express a unique set of microRNAs";
RL Dev Biol. 270:488-498(2004).
XX
RN [6]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [7]
RX PUBMED; 15978578.
RA Fu H, Tie Y, Xu C, Zhang Z, Zhu J, Shi Y, Jiang H, Sun Z, Zheng X;
RT "Identification of human fetal liver miRNAs by a novel method";
RL FEBS Lett. 579:3849-3854(2005).
XX
RN [8]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [9]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-19b; hsa-miR-19b.
DR HGNC; 31575; MIR19B1.
DR ENTREZGENE; 406980; MIR19B1.
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..38
FT /accession="MIMAT0004491"
FT /product="hsa-miR-19b-1-5p"
FT /evidence=experimental
FT /experiment="cloned [8]"
FT miRNA 54..76
FT /accession="MIMAT0000074"
FT /product="hsa-miR-19b-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3,6-9], Northern [1,5]"
XX
SQ Sequence 87 BP; 18 A; 16 C; 22 G; 0 T; 31 other;
cacuguucua ugguuaguuu ugcagguuug cauccagcug ugugauauuc ugcugugcaa 60
auccaugcaa aacugacugu gguagug 87
//
ID hsa-mir-19b-2 standard; RNA; HSA; 96 BP.
XX
AC MI0000075;
XX
DE Homo sapiens miR-19b-2 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [3]
RX PUBMED; 14573789.
RA Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ;
RT "Reduced accumulation of specific microRNAs in colorectal neoplasia";
RL Mol Cancer Res. 1:882-891(2003).
XX
RN [4]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
XX
RN [5]
RX PUBMED; 15183728.
RA Suh MR, Lee Y, Kim JY, Kim SK, Moon SH, Lee JY, Cha KY, Chung HM, Yoon HS,
RA Moon SY, Kim VN, Kim KS;
RT "Human embryonic stem cells express a unique set of microRNAs";
RL Dev Biol. 270:488-498(2004).
XX
RN [6]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [7]
RX PUBMED; 15978578.
RA Fu H, Tie Y, Xu C, Zhang Z, Zhu J, Shi Y, Jiang H, Sun Z, Zheng X;
RT "Identification of human fetal liver miRNAs by a novel method";
RL FEBS Lett. 579:3849-3854(2005).
XX
RN [8]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [9]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-19b; hsa-miR-19b.
DR HGNC; 31576; MIR19B2.
DR ENTREZGENE; 406981; MIR19B2.
XX
FH Key Location/Qualifiers
FH
FT miRNA 19..40
FT /accession="MIMAT0004492"
FT /product="hsa-miR-19b-2-5p"
FT /evidence=experimental
FT /experiment="cloned [8]"
FT miRNA 62..84
FT /accession="MIMAT0000074"
FT /product="hsa-miR-19b-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3,6-9], Northern [1,5]"
XX
SQ Sequence 96 BP; 27 A; 14 C; 19 G; 0 T; 36 other;
acauugcuac uuacaauuag uuuugcaggu uugcauuuca gcguauauau guauaugugg 60
cugugcaaau ccaugcaaaa cugauuguga uaaugu 96
//
ID hsa-mir-20a standard; RNA; HSA; 71 BP.
XX
AC MI0000076;
XX
DE Homo sapiens miR-20a stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 14573789.
RA Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ;
RT "Reduced accumulation of specific microRNAs in colorectal neoplasia";
RL Mol Cancer Res. 1:882-891(2003).
XX
RN [3]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
XX
RN [4]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [5]
RX PUBMED; 15978578.
RA Fu H, Tie Y, Xu C, Zhang Z, Zhu J, Shi Y, Jiang H, Sun Z, Zheng X;
RT "Identification of human fetal liver miRNAs by a novel method";
RL FEBS Lett. 579:3849-3854(2005).
XX
RN [6]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [7]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR HGNC; 31577; MIR20A.
DR ENTREZGENE; 406982; MIR20A.
XX
FH Key Location/Qualifiers
FH
FT miRNA 8..30
FT /accession="MIMAT0000075"
FT /product="hsa-miR-20a-5p"
FT /evidence=experimental
FT /experiment="cloned [1,4-7], Northern [1]"
FT miRNA 44..65
FT /accession="MIMAT0004493"
FT /product="hsa-miR-20a-3p"
FT /evidence=experimental
FT /experiment="cloned [6]"
XX
SQ Sequence 71 BP; 20 A; 11 C; 16 G; 0 T; 24 other;
guagcacuaa agugcuuaua gugcagguag uguuuaguua ucuacugcau uaugagcacu 60
uaaaguacug c 71
//
ID hsa-mir-21 standard; RNA; HSA; 72 BP.
XX
AC MI0000077;
XX
DE Homo sapiens miR-21 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [3]
RX PUBMED; 14573789.
RA Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ;
RT "Reduced accumulation of specific microRNAs in colorectal neoplasia";
RL Mol Cancer Res. 1:882-891(2003).
XX
RN [4]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
XX
RN [5]
RX PUBMED; 15183728.
RA Suh MR, Lee Y, Kim JY, Kim SK, Moon SH, Lee JY, Cha KY, Chung HM, Yoon HS,
RA Moon SY, Kim VN, Kim KS;
RT "Human embryonic stem cells express a unique set of microRNAs";
RL Dev Biol. 270:488-498(2004).
XX
RN [6]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [7]
RX PUBMED; 15978578.
RA Fu H, Tie Y, Xu C, Zhang Z, Zhu J, Shi Y, Jiang H, Sun Z, Zheng X;
RT "Identification of human fetal liver miRNAs by a novel method";
RL FEBS Lett. 579:3849-3854(2005).
XX
RN [8]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [9]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
RN [10]
RX PUBMED; 20158877.
RA Koh W, Sheng CT, Tan B, Lee QY, Kuznetsov V, Kiang LS, Tanavde V;
RT "Analysis of deep sequencing microRNA expression profile from human
RT embryonic stem cells derived mesenchymal stem cells reveals possible role
RT of let-7 microRNA family in downstream targeting of hepatic nuclear factor
RT 4 alpha";
RL BMC Genomics. 11 Suppl 1:S6(2010).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-21; hsa-miR-21.
DR HGNC; 31586; MIR21.
DR ENTREZGENE; 406991; MIR21.
XX
CC Mourelatos et al. named this sequence miR-21 precursor-17 and also
CC reported the exact reverse complement of this predicted stem-loop sequence
CC and erroneously assigned the name miR-104 [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 8..29
FT /accession="MIMAT0000076"
FT /product="hsa-miR-21-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3,6-9], Northern [1,5], Illumina
FT [10]"
FT miRNA 46..66
FT /accession="MIMAT0004494"
FT /product="hsa-miR-21-3p"
FT /evidence=experimental
FT /experiment="cloned [8-9]"
XX
SQ Sequence 72 BP; 16 A; 15 C; 20 G; 0 T; 21 other;
ugucggguag cuuaucagac ugauguugac uguugaaucu cauggcaaca ccagucgaug 60
ggcugucuga ca 72
//
ID hsa-mir-22 standard; RNA; HSA; 85 BP.
XX
AC MI0000078;
XX
DE Homo sapiens miR-22 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 14573789.
RA Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ;
RT "Reduced accumulation of specific microRNAs in colorectal neoplasia";
RL Mol Cancer Res. 1:882-891(2003).
XX
RN [3]
RX PUBMED; 15978578.
RA Fu H, Tie Y, Xu C, Zhang Z, Zhu J, Shi Y, Jiang H, Sun Z, Zheng X;
RT "Identification of human fetal liver miRNAs by a novel method";
RL FEBS Lett. 579:3849-3854(2005).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
RN [6]
RX PUBMED; 20158877.
RA Koh W, Sheng CT, Tan B, Lee QY, Kuznetsov V, Kiang LS, Tanavde V;
RT "Analysis of deep sequencing microRNA expression profile from human
RT embryonic stem cells derived mesenchymal stem cells reveals possible role
RT of let-7 microRNA family in downstream targeting of hepatic nuclear factor
RT 4 alpha";
RL BMC Genomics. 11 Suppl 1:S6(2010).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-22; hsa-miR-22.
DR HGNC; 31599; MIR22.
DR ENTREZGENE; 407004; MIR22.
XX
FH Key Location/Qualifiers
FH
FT miRNA 15..36
FT /accession="MIMAT0004495"
FT /product="hsa-miR-22-5p"
FT /evidence=experimental
FT /experiment="cloned [4]"
FT miRNA 53..74
FT /accession="MIMAT0000077"
FT /product="hsa-miR-22-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3-5], Northern [1], Illumina [6]"
XX
SQ Sequence 85 BP; 17 A; 24 C; 22 G; 0 T; 22 other;
ggcugagccg caguaguucu ucaguggcaa gcuuuauguc cugacccagc uaaagcugcc 60
aguugaagaa cuguugcccu cugcc 85
//
ID hsa-mir-23a standard; RNA; HSA; 73 BP.
XX
AC MI0000079;
XX
DE Homo sapiens miR-23a stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [3]
RX PUBMED; 12808467.
RA Kawasaki H, Taira K;
RT "Hes1 is a target of microRNA-23 during retinoic-acid-induced neuronal
RT differentiation of NT2 cells";
RL Nature. 423:838-842(2003).
RC Retraction: Nature 426:100(2003)
XX
RN [4]
RX PUBMED; 14573789.
RA Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ;
RT "Reduced accumulation of specific microRNAs in colorectal neoplasia";
RL Mol Cancer Res. 1:882-891(2003).
XX
RN [5]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [6]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [7]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-23a; hsa-miR-23a.
DR HGNC; 31605; MIR23A.
DR ENTREZGENE; 407010; MIR23A.
XX
CC This miRNA was previously named miR-23 [1,2] but is renamed here to avoid
CC confusion with the more recently described miR-23b (MIR:MI0000439).
CC Kawasaki and Taira reported that miR-23 regulates the transcriptional
CC repressor Hairy enhancer of split (HES1) [3]. This finding was later
CC retracted after the discovery that the regulated gene was human homolog of
CC ES1 (HES1), whose function is unknown.
XX
FH Key Location/Qualifiers
FH
FT miRNA 9..30
FT /accession="MIMAT0004496"
FT /product="hsa-miR-23a-5p"
FT /evidence=experimental
FT /experiment="cloned [6-7]"
FT miRNA 45..65
FT /accession="MIMAT0000078"
FT /product="hsa-miR-23a-3p"
FT /evidence=experimental
FT /experiment="cloned [1,4-7], Northern [1]"
XX
SQ Sequence 73 BP; 13 A; 20 C; 22 G; 0 T; 18 other;
ggccggcugg gguuccuggg gaugggauuu gcuuccuguc acaaaucaca uugccaggga 60
uuuccaaccg acc 73
//
ID hsa-mir-24-1 standard; RNA; HSA; 68 BP.
XX
AC MI0000080;
XX
DE Homo sapiens miR-24-1 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [3]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [4]
RX PUBMED; 14573789.
RA Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ;
RT "Reduced accumulation of specific microRNAs in colorectal neoplasia";
RL Mol Cancer Res. 1:882-891(2003).
XX
RN [5]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [6]
RX PUBMED; 15978578.
RA Fu H, Tie Y, Xu C, Zhang Z, Zhu J, Shi Y, Jiang H, Sun Z, Zheng X;
RT "Identification of human fetal liver miRNAs by a novel method";
RL FEBS Lett. 579:3849-3854(2005).
XX
RN [7]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [8]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
RN [9]
RX PUBMED; 20158877.
RA Koh W, Sheng CT, Tan B, Lee QY, Kuznetsov V, Kiang LS, Tanavde V;
RT "Analysis of deep sequencing microRNA expression profile from human
RT embryonic stem cells derived mesenchymal stem cells reveals possible role
RT of let-7 microRNA family in downstream targeting of hepatic nuclear factor
RT 4 alpha";
RL BMC Genomics. 11 Suppl 1:S6(2010).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-189; hsa-miR-189.
DR TARGETS:PICTAR-VERT; hsa-miR-24; hsa-miR-24.
DR HGNC; 31607; MIR24-1.
DR ENTREZGENE; 407012; MIR24-1.
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..28
FT /accession="MIMAT0000079"
FT /product="hsa-miR-24-1-5p"
FT /evidence=experimental
FT /experiment="cloned [7]"
FT /similarity="MI0000231"
FT miRNA 44..65
FT /accession="MIMAT0000080"
FT /product="hsa-miR-24-3p"
FT /evidence=experimental
FT /experiment="cloned [1,4,6-8], Northern [1], Illumina [9]"
XX
SQ Sequence 68 BP; 16 A; 18 C; 16 G; 0 T; 18 other;
cuccggugcc uacugagcug auaucaguuc ucauuuuaca cacuggcuca guucagcagg 60
aacaggag 68
//
ID hsa-mir-24-2 standard; RNA; HSA; 73 BP.
XX
AC MI0000081;
XX
DE Homo sapiens miR-24-2 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [3]
RX PUBMED; 14573789.
RA Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ;
RT "Reduced accumulation of specific microRNAs in colorectal neoplasia";
RL Mol Cancer Res. 1:882-891(2003).
XX
RN [4]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [5]
RX PUBMED; 15978578.
RA Fu H, Tie Y, Xu C, Zhang Z, Zhu J, Shi Y, Jiang H, Sun Z, Zheng X;
RT "Identification of human fetal liver miRNAs by a novel method";
RL FEBS Lett. 579:3849-3854(2005).
XX
RN [6]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [7]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
RN [8]
RX PUBMED; 20158877.
RA Koh W, Sheng CT, Tan B, Lee QY, Kuznetsov V, Kiang LS, Tanavde V;
RT "Analysis of deep sequencing microRNA expression profile from human
RT embryonic stem cells derived mesenchymal stem cells reveals possible role
RT of let-7 microRNA family in downstream targeting of hepatic nuclear factor
RT 4 alpha";
RL BMC Genomics. 11 Suppl 1:S6(2010).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-24; hsa-miR-24.
DR HGNC; 31608; MIR24-2.
DR ENTREZGENE; 407013; MIR24-2.
XX
CC mir-24-2 was identified independently by two groups. This sequence was
CC named miR-24 precursor-19 in reference [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 13..34
FT /accession="MIMAT0004497"
FT /product="hsa-miR-24-2-5p"
FT /evidence=experimental
FT /experiment="cloned [6]"
FT miRNA 50..71
FT /accession="MIMAT0000080"
FT /product="hsa-miR-24-3p"
FT /evidence=experimental
FT /experiment="cloned [1,4-7], Northern [1], Illumina [8]"
XX
SQ Sequence 73 BP; 15 A; 20 C; 20 G; 0 T; 18 other;
cucugccucc cgugccuacu gagcugaaac acaguugguu uguguacacu ggcucaguuc 60
agcaggaaca ggg 73
//
ID hsa-mir-25 standard; RNA; HSA; 84 BP.
XX
AC MI0000082;
XX
DE Homo sapiens miR-25 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-25; hsa-miR-25.
DR HGNC; 31609; MIR25.
DR ENTREZGENE; 407014; MIR25.
XX
FH Key Location/Qualifiers
FH
FT miRNA 14..34
FT /accession="MIMAT0004498"
FT /product="hsa-miR-25-5p"
FT /evidence=experimental
FT /experiment="cloned [3]"
FT miRNA 52..73
FT /accession="MIMAT0000081"
FT /product="hsa-miR-25-3p"
FT /evidence=experimental
FT /experiment="cloned [1-4], Northern [1]"
XX
SQ Sequence 84 BP; 12 A; 22 C; 31 G; 0 T; 19 other;
ggccaguguu gagaggcgga gacuugggca auugcuggac gcugcccugg gcauugcacu 60
ugucucgguc ugacagugcc ggcc 84
//
ID hsa-mir-26a-1 standard; RNA; HSA; 77 BP.
XX
AC MI0000083;
XX
DE Homo sapiens miR-26a-1 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 14573789.
RA Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ;
RT "Reduced accumulation of specific microRNAs in colorectal neoplasia";
RL Mol Cancer Res. 1:882-891(2003).
XX
RN [3]
RX PUBMED; 15183728.
RA Suh MR, Lee Y, Kim JY, Kim SK, Moon SH, Lee JY, Cha KY, Chung HM, Yoon HS,
RA Moon SY, Kim VN, Kim KS;
RT "Human embryonic stem cells express a unique set of microRNAs";
RL Dev Biol. 270:488-498(2004).
XX
RN [4]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [5]
RX PUBMED; 15978578.
RA Fu H, Tie Y, Xu C, Zhang Z, Zhu J, Shi Y, Jiang H, Sun Z, Zheng X;
RT "Identification of human fetal liver miRNAs by a novel method";
RL FEBS Lett. 579:3849-3854(2005).
XX
RN [6]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [7]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-26a; hsa-miR-26a.
DR HGNC; 31610; MIR26A1.
DR ENTREZGENE; 407015; MIR26A1.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [6].
XX
FH Key Location/Qualifiers
FH
FT miRNA 10..31
FT /accession="MIMAT0000082"
FT /product="hsa-miR-26a-5p"
FT /evidence=experimental
FT /experiment="cloned [1,4-7], Northern [1,3]"
FT miRNA 49..70
FT /accession="MIMAT0004499"
FT /product="hsa-miR-26a-1-3p"
FT /evidence=experimental
FT /experiment="cloned [6]"
XX
SQ Sequence 77 BP; 14 A; 19 C; 24 G; 0 T; 20 other;
guggccucgu ucaaguaauc caggauaggc ugugcagguc ccaaugggcc uauucuuggu 60
uacuugcacg gggacgc 77
//
ID hsa-mir-26b standard; RNA; HSA; 77 BP.
XX
AC MI0000084;
XX
DE Homo sapiens miR-26b stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 14573789.
RA Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ;
RT "Reduced accumulation of specific microRNAs in colorectal neoplasia";
RL Mol Cancer Res. 1:882-891(2003).
XX
RN [3]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-26b; hsa-miR-26b.
DR HGNC; 31612; MIR26B.
DR ENTREZGENE; 407017; MIR26B.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [4].
XX
FH Key Location/Qualifiers
FH
FT miRNA 12..32
FT /accession="MIMAT0000083"
FT /product="hsa-miR-26b-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3-5], Northern [1]"
FT miRNA 47..67
FT /accession="MIMAT0004500"
FT /product="hsa-miR-26b-3p"
FT /evidence=experimental
FT /experiment="cloned [4]"
XX
SQ Sequence 77 BP; 13 A; 20 C; 23 G; 0 T; 21 other;
ccgggaccca guucaaguaa uucaggauag guugugugcu guccagccug uucuccauua 60
cuuggcucgg ggaccgg 77
//
ID hsa-mir-27a standard; RNA; HSA; 78 BP.
XX
AC MI0000085;
XX
DE Homo sapiens miR-27a stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [3]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-27a; hsa-miR-27a.
DR HGNC; 31613; MIR27A.
DR ENTREZGENE; 407018; MIR27A.
XX
CC This miRNA was previously named miR-27 [1,2] but is renamed here to avoid
CC confusion with the more recently described miR-27b (MIR:MI0000440).
XX
FH Key Location/Qualifiers
FH
FT miRNA 10..31
FT /accession="MIMAT0004501"
FT /product="hsa-miR-27a-5p"
FT /evidence=experimental
FT /experiment="cloned [4]"
FT miRNA 51..71
FT /accession="MIMAT0000084"
FT /product="hsa-miR-27a-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3-5], Northern [1]"
XX
SQ Sequence 78 BP; 15 A; 23 C; 24 G; 0 T; 16 other;
cugaggagca gggcuuagcu gcuugugagc aggguccaca ccaagucgug uucacagugg 60
cuaaguuccg ccccccag 78
//
ID hsa-mir-28 standard; RNA; HSA; 86 BP.
XX
AC MI0000086;
XX
DE Homo sapiens miR-28 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
RN [4]
RX PUBMED; 18230126.
RA Afanasyeva EA, Hotz-Wagenblatt A, Glatting KH, Westermann F;
RT "New miRNAs cloned from neuroblastoma";
RL BMC Genomics. 9:52(2008).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-28; hsa-miR-28.
DR HGNC; 31615; MIR28.
DR ENTREZGENE; 407020; MIR28.
XX
FH Key Location/Qualifiers
FH
FT miRNA 14..35
FT /accession="MIMAT0000085"
FT /product="hsa-miR-28-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Northern [1]"
FT miRNA 54..75
FT /accession="MIMAT0004502"
FT /product="hsa-miR-28-3p"
FT /evidence=experimental
FT /experiment="cloned [2-4]"
XX
SQ Sequence 86 BP; 16 A; 24 C; 21 G; 0 T; 25 other;
gguccuugcc cucaaggagc ucacagucua uugaguuacc uuucugacuu ucccacuaga 60
uugugagcuc cuggagggca ggcacu 86
//
ID hsa-mir-29a standard; RNA; HSA; 64 BP.
XX
AC MI0000087;
XX
DE Homo sapiens miR-29a stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 14573789.
RA Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ;
RT "Reduced accumulation of specific microRNAs in colorectal neoplasia";
RL Mol Cancer Res. 1:882-891(2003).
XX
RN [3]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
XX
RN [4]
RX PUBMED; 15183728.
RA Suh MR, Lee Y, Kim JY, Kim SK, Moon SH, Lee JY, Cha KY, Chung HM, Yoon HS,
RA Moon SY, Kim VN, Kim KS;
RT "Human embryonic stem cells express a unique set of microRNAs";
RL Dev Biol. 270:488-498(2004).
XX
RN [5]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [6]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [7]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
RN [8]
RX PUBMED; 20158877.
RA Koh W, Sheng CT, Tan B, Lee QY, Kuznetsov V, Kiang LS, Tanavde V;
RT "Analysis of deep sequencing microRNA expression profile from human
RT embryonic stem cells derived mesenchymal stem cells reveals possible role
RT of let-7 microRNA family in downstream targeting of hepatic nuclear factor
RT 4 alpha";
RL BMC Genomics. 11 Suppl 1:S6(2010).
XX
DR RFAM; RF00074; mir-29.
DR TARGETS:PICTAR-VERT; hsa-miR-29a; hsa-miR-29a.
DR HGNC; 31616; MIR29A.
DR ENTREZGENE; 407021; MIR29A.
XX
CC miR-29a was previously know as miR-29 here and in [1]. The mature
CC sequence shown here represents the most commonly cloned form from
CC large-scale cloning studies [6].
XX
FH Key Location/Qualifiers
FH
FT miRNA 4..25
FT /accession="MIMAT0004503"
FT /product="hsa-miR-29a-5p"
FT /evidence=experimental
FT /experiment="cloned [6]"
FT miRNA 42..63
FT /accession="MIMAT0000086"
FT /product="hsa-miR-29a-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3,5-7], Northern [1,4], Illumina
FT [8]"
XX
SQ Sequence 64 BP; 17 A; 10 C; 11 G; 0 T; 26 other;
augacugauu ucuuuuggug uucagaguca auauaauuuu cuagcaccau cugaaaucgg 60
uuau 64
//
ID hsa-mir-30a standard; RNA; HSA; 71 BP.
XX
AC MI0000088;
XX
DE Homo sapiens miR-30a stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [3]
RX PUBMED; 14573789.
RA Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ;
RT "Reduced accumulation of specific microRNAs in colorectal neoplasia";
RL Mol Cancer Res. 1:882-891(2003).
XX
RN [4]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [5]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [6]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-30a-3p; hsa-miR-30a-3p.
DR TARGETS:PICTAR-VERT; hsa-miR-30a-5p; hsa-miR-30a-5p.
DR HGNC; 31624; MIR30A.
DR ENTREZGENE; 407029; MIR30A.
XX
CC The mature sequences miR-30 [1] and miR-97 [2] appear to originate from
CC the same precursor. Subsequent data confirm that both arms of the
CC precursor appear to give rise to mature miRNA sequences (Pfeffer S, pers.
CC comm.). Landgraf et al. later showed that the 5' product is the
CC predominant one [5]. Related miRNAs are processed from the 5' arms of
CC other precursor loci (mir-30b, MIR:MI0000441; mir-30c-1, MIR:MI0000736;
CC mir-30c-2, MIR:MI0000254; mir-30d, MIR:MI0000255; mir-30e, MI0000749).
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..27
FT /accession="MIMAT0000087"
FT /product="hsa-miR-30a-5p"
FT /evidence=experimental
FT /experiment="cloned [2,4-6]"
FT miRNA 47..68
FT /accession="MIMAT0000088"
FT /product="hsa-miR-30a-3p"
FT /evidence=experimental
FT /experiment="cloned [1,4-5], Northern [1]"
XX
SQ Sequence 71 BP; 16 A; 17 C; 21 G; 0 T; 17 other;
gcgacuguaa acauccucga cuggaagcug ugaagccaca gaugggcuuu cagucggaug 60
uuugcagcug c 71
//
ID hsa-mir-31 standard; RNA; HSA; 71 BP.
XX
AC MI0000089;
XX
DE Homo sapiens miR-31 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-31; hsa-miR-31.
DR HGNC; 31630; MIR31.
DR ENTREZGENE; 407035; MIR31.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [2]. The 5' end of the miRNA may be
CC offset with respect to previous annotations.
XX
FH Key Location/Qualifiers
FH
FT miRNA 8..28
FT /accession="MIMAT0000089"
FT /product="hsa-miR-31-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Northern [1]"
FT miRNA 44..65
FT /accession="MIMAT0004504"
FT /product="hsa-miR-31-3p"
FT /evidence=experimental
FT /experiment="cloned [2]"
XX
SQ Sequence 71 BP; 18 A; 16 C; 20 G; 0 T; 17 other;
ggagaggagg caagaugcug gcauagcugu ugaacuggga accugcuaug ccaacauauu 60
gccaucuuuc c 71
//
ID hsa-mir-32 standard; RNA; HSA; 70 BP.
XX
AC MI0000090;
XX
DE Homo sapiens miR-32 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-32; hsa-miR-32.
DR HGNC; 31631; MIR32.
DR ENTREZGENE; 407036; MIR32.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..27
FT /accession="MIMAT0000090"
FT /product="hsa-miR-32-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1]"
FT miRNA 47..68
FT /accession="MIMAT0004505"
FT /product="hsa-miR-32-3p"
FT /evidence=experimental
FT /experiment="cloned [2]"
XX
SQ Sequence 70 BP; 17 A; 11 C; 16 G; 0 T; 26 other;
ggagauauug cacauuacua aguugcaugu ugucacggcc ucaaugcaau uuagugugug 60
ugauauuuuc 70
//
ID hsa-mir-33a standard; RNA; HSA; 69 BP.
XX
AC MI0000091;
XX
DE Homo sapiens miR-33a stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-33; hsa-miR-33.
DR HGNC; 31634; MIR33A.
DR ENTREZGENE; 407039; MIR33A.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..26
FT /accession="MIMAT0000091"
FT /product="hsa-miR-33a-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1]"
FT miRNA 46..67
FT /accession="MIMAT0004506"
FT /product="hsa-miR-33a-3p"
FT /evidence=experimental
FT /experiment="cloned [2]"
XX
SQ Sequence 69 BP; 13 A; 15 C; 18 G; 0 T; 23 other;
cuguggugca uuguaguugc auugcauguu cuggugguac ccaugcaaug uuuccacagu 60
gcaucacag 69
//
ID hsa-mir-92a-1 standard; RNA; HSA; 78 BP.
XX
AC MI0000093;
XX
DE Homo sapiens miR-92a-1 stem-loop
XX
RN [1]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [2]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [3]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
XX
RN [4]
RX PUBMED; 15183728.
RA Suh MR, Lee Y, Kim JY, Kim SK, Moon SH, Lee JY, Cha KY, Chung HM, Yoon HS,
RA Moon SY, Kim VN, Kim KS;
RT "Human embryonic stem cells express a unique set of microRNAs";
RL Dev Biol. 270:488-498(2004).
XX
RN [5]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [6]
RX PUBMED; 15978578.
RA Fu H, Tie Y, Xu C, Zhang Z, Zhu J, Shi Y, Jiang H, Sun Z, Zheng X;
RT "Identification of human fetal liver miRNAs by a novel method";
RL FEBS Lett. 579:3849-3854(2005).
XX
RN [7]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [8]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-92; hsa-miR-92.
DR HGNC; 31643; MIR92A1.
DR ENTREZGENE; 407048; MIR92A1.
XX
CC Human miR-92a (previously named miR-92 here) has two predicted hairpin
CC precursor sequences: mir-92a-1 (MIR:MI0000093) on chromosome 13 (named
CC mir-92-13 in [1]) and mir-92a-2 (MIR:MI0000094) on chromosome X (named
CC mir-92-X in [1]). miR-92a has also been cloned from mouse embryonic stem
CC cells [2] and is predicted to be expressed from two closely related
CC precursor hairpins (MIR:MI0000719 and MIR:MI0000580). The mature sequence
CC shown here represents the most commonly cloned form from large-scale
CC cloning studies [7].
XX
FH Key Location/Qualifiers
FH
FT miRNA 11..33
FT /accession="MIMAT0004507"
FT /product="hsa-miR-92a-1-5p"
FT /evidence=experimental
FT /experiment="cloned [7-8]"
FT miRNA 48..69
FT /accession="MIMAT0000092"
FT /product="hsa-miR-92a-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3,5-8], Northern [4]"
XX
SQ Sequence 78 BP; 10 A; 15 C; 23 G; 0 T; 30 other;
cuuucuacac agguugggau cgguugcaau gcuguguuuc uguaugguau ugcacuuguc 60
ccggccuguu gaguuugg 78
//
ID hsa-mir-92a-2 standard; RNA; HSA; 75 BP.
XX
AC MI0000094;
XX
DE Homo sapiens miR-92a-2 stem-loop
XX
RN [1]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [2]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [3]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
XX
RN [4]
RX PUBMED; 15183728.
RA Suh MR, Lee Y, Kim JY, Kim SK, Moon SH, Lee JY, Cha KY, Chung HM, Yoon HS,
RA Moon SY, Kim VN, Kim KS;
RT "Human embryonic stem cells express a unique set of microRNAs";
RL Dev Biol. 270:488-498(2004).
XX
RN [5]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [6]
RX PUBMED; 15978578.
RA Fu H, Tie Y, Xu C, Zhang Z, Zhu J, Shi Y, Jiang H, Sun Z, Zheng X;
RT "Identification of human fetal liver miRNAs by a novel method";
RL FEBS Lett. 579:3849-3854(2005).
XX
RN [7]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [8]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-92; hsa-miR-92.
DR HGNC; 31644; MIR92A2.
DR ENTREZGENE; 407049; MIR92A2.
XX
CC Human miR-92a (previously named miR-92 here) has two predicted hairpin
CC precursor sequences: mir-92a-1 (MIR:MI0000093) on chromosome 13 (named
CC mir-92-13 in [1]) and mir-92a-2 (MIR:MI0000094) on chromosome X (named
CC mir-92-X in [1]). miR-92a has also been cloned from mouse embryonic stem
CC cells [2] and is predicted to be expressed from two closely related
CC precursor hairpins (MIR:MI0000719 and MIR:MI0000580). The mature sequence
CC shown here represents the most commonly cloned form from large-scale
CC cloning studies [7].
XX
FH Key Location/Qualifiers
FH
FT miRNA 9..30
FT /accession="MIMAT0004508"
FT /product="hsa-miR-92a-2-5p"
FT /evidence=experimental
FT /experiment="cloned [7]"
FT miRNA 48..69
FT /accession="MIMAT0000092"
FT /product="hsa-miR-92a-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3,5-8], Northern [4]"
XX
SQ Sequence 75 BP; 14 A; 14 C; 20 G; 0 T; 27 other;
ucaucccugg guggggauuu guugcauuac uuguguucua uauaaaguau ugcacuuguc 60
ccggccugug gaaga 75
//
ID hsa-mir-93 standard; RNA; HSA; 80 BP.
XX
AC MI0000095;
XX
DE Homo sapiens miR-93 stem-loop
XX
RN [1]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [2]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
XX
RN [3]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [4]
RX PUBMED; 15978578.
RA Fu H, Tie Y, Xu C, Zhang Z, Zhu J, Shi Y, Jiang H, Sun Z, Zheng X;
RT "Identification of human fetal liver miRNAs by a novel method";
RL FEBS Lett. 579:3849-3854(2005).
XX
RN [5]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [6]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-93; hsa-miR-93.
DR HGNC; 31645; MIR93.
DR ENTREZGENE; 407050; MIR93.
XX
CC Mourelatos et al. identified two copies of this sequence mapping to
CC chromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 [1].
CC Subsequent genome assemblies suggest the presence of only one miR-93 locus
CC on chromosome 7. The mature sequence shown here represents the most
CC commonly cloned form from large-scale cloning studies [5]. The 5' end of
CC the miRNA may be offset with respect to previous annotations.
XX
FH Key Location/Qualifiers
FH
FT miRNA 11..33
FT /accession="MIMAT0000093"
FT /product="hsa-miR-93-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3-6], Northern [4]"
FT miRNA 50..71
FT /accession="MIMAT0004509"
FT /product="hsa-miR-93-3p"
FT /evidence=experimental
FT /experiment="cloned [5]"
XX
SQ Sequence 80 BP; 14 A; 25 C; 23 G; 0 T; 18 other;
cugggggcuc caaagugcug uucgugcagg uagugugauu acccaaccua cugcugagcu 60
agcacuuccc gagcccccgg 80
//
ID hsa-mir-95 standard; RNA; HSA; 81 BP.
XX
AC MI0000097;
XX
DE Homo sapiens miR-95 stem-loop
XX
RN [1]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 23034410.
RA Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H,
RA Khaitovich P, Kaessmann H;
RT "Birth and expression evolution of mammalian microRNA genes";
RL Genome Res. 23:34-45(2013).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-95; hsa-miR-95.
DR HGNC; 31647; MIR95.
DR ENTREZGENE; 407052; MIR95.
XX
CC This sequence is localised to chromosome 4 and was named mir-95-4 in
CC reference [1].
XX
FH Key Location/Qualifiers
FH
FT miRNA 15..35
FT /accession="MIMAT0026473"
FT /product="hsa-miR-95-5p"
FT /evidence=experimental
FT /experiment="Illumina [3]"
FT miRNA 49..70
FT /accession="MIMAT0000094"
FT /product="hsa-miR-95-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Illumina [3]"
XX
SQ Sequence 81 BP; 24 A; 16 C; 17 G; 0 T; 24 other;
aacacagugg gcacucaaua aaugucuguu gaauugaaau gcguuacauu caacggguau 60
uuauugagca cccacucugu g 81
//
ID hsa-mir-96 standard; RNA; HSA; 78 BP.
XX
AC MI0000098;
XX
DE Homo sapiens miR-96 stem-loop
XX
RN [1]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-96; hsa-miR-96.
DR HGNC; 31648; MIR96.
DR ENTREZGENE; 407053; MIR96.
XX
CC This sequence is localised to chromosome 7 and was named mir-96-7 in
CC reference [1]. The mature sequence shown here represents the most
CC commonly cloned form from large-scale cloning studies [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 9..31
FT /accession="MIMAT0000095"
FT /product="hsa-miR-96-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3]"
FT miRNA 52..73
FT /accession="MIMAT0004510"
FT /product="hsa-miR-96-3p"
FT /evidence=experimental
FT /experiment="cloned [2]"
XX
SQ Sequence 78 BP; 16 A; 18 C; 19 G; 0 T; 25 other;
uggccgauuu uggcacuagc acauuuuugc uugugucucu ccgcucugag caaucaugug 60
cagugccaau augggaaa 78
//
ID hsa-mir-98 standard; RNA; HSA; 119 BP.
XX
AC MI0000100;
XX
DE Homo sapiens miR-98 stem-loop
XX
RN [1]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
RN [4]
RX PUBMED; 22282338.
RA Voellenkle C, Rooij Jv, Guffanti A, Brini E, Fasanaro P, Isaia E, Croft L,
RA David M, Capogrossi MC, Moles A, Felsani A, Martelli F;
RT "Deep-sequencing of endothelial cells exposed to hypoxia reveals the
RT complexity of known and novel microRNAs";
RL RNA. 18:472-484(2012).
XX
DR RFAM; RF00027; let-7.
DR TARGETS:PICTAR-VERT; hsa-miR-98; hsa-miR-98.
DR HGNC; 31649; MIR98.
DR ENTREZGENE; 407054; MIR98.
XX
CC This sequence is localised to chromosome X and was named mir-98-X in
CC reference [1]. The predicted stem-loop precursor sequence is clearly
CC related to let-7.
XX
FH Key Location/Qualifiers
FH
FT miRNA 22..43
FT /accession="MIMAT0000096"
FT /product="hsa-miR-98-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3], SOLiD [4]"
FT miRNA 80..101
FT /accession="MIMAT0022842"
FT /product="hsa-miR-98-3p"
FT /evidence=experimental
FT /experiment="SOLiD [4]"
XX
SQ Sequence 119 BP; 30 A; 19 C; 32 G; 0 T; 38 other;
aggauucugc ucaugccagg gugagguagu aaguuguauu guuguggggu agggauauua 60
ggccccaauu agaagauaac uauacaacuu acuacuuucc cuggugugug gcauauuca 119
//
ID hsa-mir-99a standard; RNA; HSA; 81 BP.
XX
AC MI0000101;
XX
DE Homo sapiens miR-99a stem-loop
XX
RN [1]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR RFAM; RF00104; mir-10.
DR TARGETS:PICTAR-VERT; hsa-miR-99a; hsa-miR-99a.
DR HGNC; 31650; MIR99A.
DR ENTREZGENE; 407055; MIR99A.
XX
CC This sequence is localised to chromosome 21 and was named mir-99-21 in
CC reference [1].
XX
FH Key Location/Qualifiers
FH
FT miRNA 13..34
FT /accession="MIMAT0000097"
FT /product="hsa-miR-99a-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3]"
FT miRNA 50..71
FT /accession="MIMAT0004511"
FT /product="hsa-miR-99a-3p"
FT /evidence=experimental
FT /experiment="cloned [2]"
XX
SQ Sequence 81 BP; 16 A; 20 C; 23 G; 0 T; 22 other;
cccauuggca uaaacccgua gauccgaucu uguggugaag uggaccgcac aagcucgcuu 60
cuaugggucu gugucagugu g 81
//
ID hsa-mir-100 standard; RNA; HSA; 80 BP.
XX
AC MI0000102;
XX
DE Homo sapiens miR-100 stem-loop
XX
RN [1]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
RN [4]
RX PUBMED; 20158877.
RA Koh W, Sheng CT, Tan B, Lee QY, Kuznetsov V, Kiang LS, Tanavde V;
RT "Analysis of deep sequencing microRNA expression profile from human
RT embryonic stem cells derived mesenchymal stem cells reveals possible role
RT of let-7 microRNA family in downstream targeting of hepatic nuclear factor
RT 4 alpha";
RL BMC Genomics. 11 Suppl 1:S6(2010).
XX
DR RFAM; RF00104; mir-10.
DR TARGETS:PICTAR-VERT; hsa-miR-100; hsa-miR-100.
DR HGNC; 31487; MIR100.
DR ENTREZGENE; 406892; MIR100.
XX
CC This sequence is localised to chromosome 11 and was named mir-100-11 in
CC reference [1].
XX
FH Key Location/Qualifiers
FH
FT miRNA 13..34
FT /accession="MIMAT0000098"
FT /product="hsa-miR-100-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Illumina [4]"
FT miRNA 48..69
FT /accession="MIMAT0004512"
FT /product="hsa-miR-100-3p"
FT /evidence=experimental
FT /experiment="cloned [2]"
XX
SQ Sequence 80 BP; 18 A; 18 C; 19 G; 0 T; 25 other;
ccuguugcca caaacccgua gauccgaacu ugugguauua guccgcacaa gcuuguaucu 60
auagguaugu gucuguuagg 80
//
ID hsa-mir-101-1 standard; RNA; HSA; 75 BP.
XX
AC MI0000103;
XX
DE Homo sapiens miR-101-1 stem-loop
XX
RN [1]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [2]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-101; hsa-miR-101.
DR HGNC; 31488; MIR101-1.
DR ENTREZGENE; 406893; MIR101-1.
XX
CC Reference [1] reports two miR-101 precursor hairpin structures in human,
CC on chromosome 1 (MIR:MI0000103) and 9 (MIR:MI0000739, named
CC mir-101-precursor-9 in [1]). The mature sequence shown here represents
CC the most commonly cloned form from large-scale cloning studies [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 11..32
FT /accession="MIMAT0004513"
FT /product="hsa-miR-101-5p"
FT /evidence=experimental
FT /experiment="cloned [3-4]"
FT miRNA 47..67
FT /accession="MIMAT0000099"
FT /product="hsa-miR-101-3p"
FT /evidence=experimental
FT /experiment="cloned [1-4]"
XX
SQ Sequence 75 BP; 19 A; 15 C; 19 G; 0 T; 22 other;
ugcccuggcu caguuaucac agugcugaug cugucuauuc uaaagguaca guacugugau 60
aacugaagga uggca 75
//
ID hsa-mir-29b-1 standard; RNA; HSA; 81 BP.
XX
AC MI0000105;
XX
DE Homo sapiens miR-29b-1 stem-loop
XX
RN [1]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [2]
RX PUBMED; 15183728.
RA Suh MR, Lee Y, Kim JY, Kim SK, Moon SH, Lee JY, Cha KY, Chung HM, Yoon HS,
RA Moon SY, Kim VN, Kim KS;
RT "Human embryonic stem cells express a unique set of microRNAs";
RL Dev Biol. 270:488-498(2004).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR MIR; MI0000143; mmu-mir-29b-1.
DR RFAM; RF00074; mir-29.
DR TARGETS:PICTAR-VERT; hsa-miR-29b; hsa-miR-29b.
DR HGNC; 31619; MIR29B1.
DR ENTREZGENE; 407024; MIR29B1.
XX
CC Mourelatos et al. identified two copies of this sequence mapping to
CC chromosome 7, and assigned the names mir-102-7.1 and mir-102-7.2 [1].
CC Subsequent genome assemblies suggest the presence of only one miR-102
CC locus on chromosome 7. Human miR-102 is a homologue of mouse miR-29b
CC (MIR:MI0000143) and so has been renamed here for consistency.
XX
FH Key Location/Qualifiers
FH
FT miRNA 10..33
FT /accession="MIMAT0004514"
FT /product="hsa-miR-29b-1-5p"
FT /evidence=experimental
FT /experiment="cloned [3-4]"
FT miRNA 51..73
FT /accession="MIMAT0000100"
FT /product="hsa-miR-29b-3p"
FT /evidence=experimental
FT /experiment="cloned [1-4], Northern [2]"
XX
SQ Sequence 81 BP; 19 A; 10 C; 22 G; 0 T; 30 other;
cuucaggaag cugguuucau auggugguuu agauuuaaau agugauuguc uagcaccauu 60
ugaaaucagu guucuugggg g 81
//
ID hsa-mir-29b-2 standard; RNA; HSA; 81 BP.
XX
AC MI0000107;
XX
DE Homo sapiens miR-29b-2 stem-loop
XX
RN [1]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [2]
RX PUBMED; 15183728.
RA Suh MR, Lee Y, Kim JY, Kim SK, Moon SH, Lee JY, Cha KY, Chung HM, Yoon HS,
RA Moon SY, Kim VN, Kim KS;
RT "Human embryonic stem cells express a unique set of microRNAs";
RL Dev Biol. 270:488-498(2004).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR MIR; MI0000712; mmu-mir-29b-2.
DR RFAM; RF00074; mir-29.
DR TARGETS:PICTAR-VERT; hsa-miR-29b; hsa-miR-29b.
DR HGNC; 31620; MIR29B2.
DR ENTREZGENE; 407025; MIR29B2.
XX
CC This sequence was named mir-102-1 in reference [1]. Human miR-102 is a
CC homologue of mouse miR-29b (MIR:MI0000143) and so has been renamed here
CC for consistency.
XX
FH Key Location/Qualifiers
FH
FT miRNA 11..32
FT /accession="MIMAT0004515"
FT /product="hsa-miR-29b-2-5p"
FT /evidence=experimental
FT /experiment="cloned [3]"
FT miRNA 52..74
FT /accession="MIMAT0000100"
FT /product="hsa-miR-29b-3p"
FT /evidence=experimental
FT /experiment="cloned [1-4], Northern [2]"
XX
SQ Sequence 81 BP; 17 A; 14 C; 18 G; 0 T; 32 other;
cuucuggaag cugguuucac augguggcuu agauuuuucc aucuuuguau cuagcaccau 60
uugaaaucag uguuuuagga g 81
//
ID hsa-mir-103a-2 standard; RNA; HSA; 78 BP.
XX
AC MI0000108;
XX
DE Homo sapiens miR-103a-2 stem-loop
XX
RN [1]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [2]
RX PUBMED; 15183728.
RA Suh MR, Lee Y, Kim JY, Kim SK, Moon SH, Lee JY, Cha KY, Chung HM, Yoon HS,
RA Moon SY, Kim VN, Kim KS;
RT "Human embryonic stem cells express a unique set of microRNAs";
RL Dev Biol. 270:488-498(2004).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
RN [5]
RX PUBMED; 19144710.
RA Zhu JY, Pfuhl T, Motsch N, Barth S, Nicholls J, Grasser F, Meister G;
RT "Identification of novel Epstein-Barr virus microRNA genes from
RT nasopharyngeal carcinomas";
RL J Virol. 83:3333-3341(2009).
XX
RN [6]
RX PUBMED; 20158877.
RA Koh W, Sheng CT, Tan B, Lee QY, Kuznetsov V, Kiang LS, Tanavde V;
RT "Analysis of deep sequencing microRNA expression profile from human
RT embryonic stem cells derived mesenchymal stem cells reveals possible role
RT of let-7 microRNA family in downstream targeting of hepatic nuclear factor
RT 4 alpha";
RL BMC Genomics. 11 Suppl 1:S6(2010).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-103; hsa-miR-103.
DR HGNC; 31491; MIR103-2.
DR ENTREZGENE; 406896; MIR103A2.
XX
CC This sequence was localised to chromosome 20 and named mir-103-20 in
CC reference [1].
XX
FH Key Location/Qualifiers
FH
FT miRNA 11..33
FT /accession="MIMAT0009196"
FT /product="hsa-miR-103a-2-5p"
FT /evidence=experimental
FT /experiment="454 [5]"
FT miRNA 48..70
FT /accession="MIMAT0000101"
FT /product="hsa-miR-103a-3p"
FT /evidence=experimental
FT /experiment="cloned [1-4], Northern [2], Illumina [6]"
XX
SQ Sequence 78 BP; 19 A; 17 C; 18 G; 0 T; 24 other;
uugugcuuuc agcuucuuua cagugcugcc uuguagcauu caggucaagc agcauuguac 60
agggcuauga aagaacca 78
//
ID hsa-mir-103a-1 standard; RNA; HSA; 78 BP.
XX
AC MI0000109;
XX
DE Homo sapiens miR-103a-1 stem-loop
XX
RN [1]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [2]
RX PUBMED; 15183728.
RA Suh MR, Lee Y, Kim JY, Kim SK, Moon SH, Lee JY, Cha KY, Chung HM, Yoon HS,
RA Moon SY, Kim VN, Kim KS;
RT "Human embryonic stem cells express a unique set of microRNAs";
RL Dev Biol. 270:488-498(2004).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
RN [5]
RX PUBMED; 20158877.
RA Koh W, Sheng CT, Tan B, Lee QY, Kuznetsov V, Kiang LS, Tanavde V;
RT "Analysis of deep sequencing microRNA expression profile from human
RT embryonic stem cells derived mesenchymal stem cells reveals possible role
RT of let-7 microRNA family in downstream targeting of hepatic nuclear factor
RT 4 alpha";
RL BMC Genomics. 11 Suppl 1:S6(2010).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-103; hsa-miR-103.
DR HGNC; 31490; MIR103-1.
DR ENTREZGENE; 406895; MIR103A1.
XX
FH Key Location/Qualifiers
FH
FT miRNA 11..33
FT /accession="MIMAT0037306"
FT /product="hsa-miR-103a-1-5p"
FT /evidence=not_experimental
FT miRNA 48..70
FT /accession="MIMAT0000101"
FT /product="hsa-miR-103a-3p"
FT /evidence=experimental
FT /experiment="cloned [1-4], Northern [2], Illumina [5]"
XX
SQ Sequence 78 BP; 16 A; 18 C; 20 G; 0 T; 24 other;
uacugcccuc ggcuucuuua cagugcugcc uuguugcaua uggaucaagc agcauuguac 60
agggcuauga aggcauug 78
//
ID hsa-mir-105-1 standard; RNA; HSA; 81 BP.
XX
AC MI0000111;
XX
DE Homo sapiens miR-105-1 stem-loop
XX
RN [1]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-105; hsa-miR-105.
DR HGNC; 31492; MIR105-1.
DR ENTREZGENE; 406897; MIR105-1.
XX
CC Mourelatos et al. [1] reported two identical predicted stem loop sequences
CC located on chromosome X, which they named mir-105-X.1 and mir-105-X.2.
CC These sequences have been renamed mir-105-1 (MIR:MI0000111) and mir-105-2
CC (MIR:MI0000112) here. mir-105-2 differs slightly from that published in
CC [1] and deposited in EMBL (EMBL:AF480548). The mature sequence shown here
CC represents the most commonly cloned form from large-scale cloning studies
CC [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 13..35
FT /accession="MIMAT0000102"
FT /product="hsa-miR-105-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2]"
FT miRNA 51..72
FT /accession="MIMAT0004516"
FT /product="hsa-miR-105-3p"
FT /evidence=experimental
FT /experiment="cloned [2]"
XX
SQ Sequence 81 BP; 14 A; 19 C; 24 G; 0 T; 24 other;
ugugcaucgu ggucaaaugc ucagacuccu gugguggcug cucaugcacc acggauguuu 60
gagcaugugc uacggugucu a 81
//
ID hsa-mir-105-2 standard; RNA; HSA; 81 BP.
XX
AC MI0000112;
XX
DE Homo sapiens miR-105-2 stem-loop
XX
RN [1]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-105; hsa-miR-105.
DR HGNC; 31493; MIR105-2.
DR ENTREZGENE; 406898; MIR105-2.
XX
CC Mourelatos et al. [1] reported two identical predicted stem loop sequences
CC located on chromosome X, which they named mir-105-X.1 and mir-105-X.2.
CC These sequences have been renamed mir-105-1 (MIR:MI0000111) and mir-105-2
CC (MIR:MI0000112) here. mir-105-2 differs slightly from that published in
CC [1] and deposited in EMBL (EMBL:AF480548). The mature sequence shown here
CC represents the most commonly cloned form from large-scale cloning studies
CC [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 13..35
FT /accession="MIMAT0000102"
FT /product="hsa-miR-105-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2]"
FT miRNA 51..72
FT /accession="MIMAT0004516"
FT /product="hsa-miR-105-3p"
FT /evidence=experimental
FT /experiment="cloned [2]"
XX
SQ Sequence 81 BP; 14 A; 17 C; 24 G; 0 T; 26 other;
ugugcaucgu ggucaaaugc ucagacuccu gugguggcug cuuaugcacc acggauguuu 60
gagcaugugc uauggugucu a 81
//
ID hsa-mir-106a standard; RNA; HSA; 81 BP.
XX
AC MI0000113;
XX
DE Homo sapiens miR-106a stem-loop
XX
RN [1]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [2]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
DR MIR; MI0000071; hsa-mir-17.
DR RFAM; RF00051; mir-17.
DR TARGETS:PICTAR-VERT; hsa-miR-106a; hsa-miR-106a.
DR HGNC; 31494; MIR106A.
DR ENTREZGENE; 406899; MIR106A.
XX
CC This miRNA was not cloned in reference [1], rather it was identified by
CC homology to miR-91 (MIR:MI0000071). This sequence is localised to
CC chromosome X and was named mir-106-X in [1]. Mouse and human miR-106a
CC (MIR:MI0000406 and MIR:MI0000113) differ at two positions but the
CC precursor sequences are clearly closely related. The sequences are also
CC related to mir-17 (MIR:MI0000071 and MIR:MI0000687). The mature sequence
CC shown here represents the most commonly cloned form from large-scale
CC cloning studies [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 13..35
FT /accession="MIMAT0000103"
FT /product="hsa-miR-106a-5p"
FT /evidence=experimental
FT /experiment="cloned [2-3]"
FT miRNA 50..71
FT /accession="MIMAT0004517"
FT /product="hsa-miR-106a-3p"
FT /evidence=experimental
FT /experiment="cloned [3]"
XX
SQ Sequence 81 BP; 21 A; 17 C; 17 G; 0 T; 26 other;
ccuuggccau guaaaagugc uuacagugca gguagcuuuu ugagaucuac ugcaauguaa 60
gcacuucuua cauuaccaug g 81
//
ID hsa-mir-107 standard; RNA; HSA; 81 BP.
XX
AC MI0000114;
XX
DE Homo sapiens miR-107 stem-loop
XX
RN [1]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
DR MIR; MI0000108; .
DR TARGETS:PICTAR-VERT; hsa-miR-107; hsa-miR-107.
DR HGNC; 31496; MIR107.
DR ENTREZGENE; 406901; MIR107.
XX
CC This miRNA was identified by homology to miR-103 [1], and later verified
CC by cloning in human [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 50..72
FT /accession="MIMAT0000104"
FT /product="hsa-miR-107"
FT /evidence=experimental
FT /experiment="cloned [2]"
XX
SQ Sequence 81 BP; 18 A; 19 C; 19 G; 0 T; 25 other;
cucucugcuu ucagcuucuu uacaguguug ccuuguggca uggaguucaa gcagcauugu 60
acagggcuau caaagcacag a 81
//
ID hsa-mir-16-2 standard; RNA; HSA; 81 BP.
XX
AC MI0000115;
XX
DE Homo sapiens miR-16-2 stem-loop
XX
RN [1]
RX MEDLINE; 21912064.
RX PUBMED; 11914277.
RA Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L,
RA Rappsilber J, Mann M, Dreyfuss G;
RT "miRNPs: a novel class of ribonucleoproteins containing numerous
RT microRNAs";
RL Genes Dev. 16:720-728(2002).
XX
RN [2]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [3]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [4]
RX PUBMED; 15183728.
RA Suh MR, Lee Y, Kim JY, Kim SK, Moon SH, Lee JY, Cha KY, Chung HM, Yoon HS,
RA Moon SY, Kim VN, Kim KS;
RT "Human embryonic stem cells express a unique set of microRNAs";
RL Dev Biol. 270:488-498(2004).
XX
RN [5]
RX PUBMED; 14573789.
RA Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ;
RT "Reduced accumulation of specific microRNAs in colorectal neoplasia";
RL Mol Cancer Res. 1:882-891(2003).
XX
RN [6]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [7]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [8]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-16; hsa-miR-16.
DR HGNC; 31546; MIR16-2.
DR ENTREZGENE; 406951; MIR16-2.
XX
CC This entry represents a second putative hairpin precursor sequence for
CC miR-16, located on chromosome 3 (see also MIR:MI0000070). The sequence
CC was previously named mir-16-3 here and in references [1] and [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 10..31
FT /accession="MIMAT0000069"
FT /product="hsa-miR-16-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3-4,6-8], Northern [3]"
FT miRNA 53..74
FT /accession="MIMAT0004518"
FT /product="hsa-miR-16-2-3p"
FT /evidence=experimental
FT /experiment="cloned [7]"
XX
SQ Sequence 81 BP; 25 A; 15 C; 15 G; 0 T; 26 other;
guuccacucu agcagcacgu aaauauuggc guagugaaau auauauuaaa caccaauauu 60
acugugcugc uuuaguguga c 81
//
ID dme-mir-1 standard; RNA; DME; 91 BP.
XX
AC MI0000116;
XX
DE Drosophila melanogaster miR-1 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [3]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [4]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [5]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR RFAM; RF00103; mir-1.
DR TARGETS:MIRTE; miR-1; miR-1.
DR TARGETS:PICTAR-FLY; dme-miR-1; dme-miR-1.
XX
FH Key Location/Qualifiers
FH
FT miRNA 18..39
FT /accession="MIMAT0020779"
FT /product="dme-miR-1-5p"
FT /evidence=not_experimental
FT miRNA 56..77
FT /accession="MIMAT0000105"
FT /product="dme-miR-1-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1-2], 454 [4-5],
FT Illumina [5]"
FT /similarity="MI0000116"
XX
SQ Sequence 91 BP; 27 A; 15 C; 21 G; 0 T; 28 other;
uucagccuuu gagaguucca ugcuuccuug cauucaauag uuauauucaa gcauauggaa 60
uguaaagaag uauggagcga aaucuggcga g 91
//
ID dme-mir-2a-1 standard; RNA; DME; 76 BP.
XX
AC MI0000117;
XX
DE Drosophila melanogaster miR-2a-1 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 14691535.
RA Stark A, Brennecke J, Russell RB, Cohen SM;
RT "Identification of Drosophila MicroRNA targets";
RL PLoS Biol. 1:E60(2003).
XX
RN [3]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [4]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [5]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [6]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR RFAM; RF00047; mir-2.
DR TARGETS:MIRTE; miR-2a; miR-2a.
DR TARGETS:PICTAR-FLY; dme-miR-2a; dme-miR-2a.
XX
CC Stark et al. [2] have identified targets for miR-2 in Drosophila using
CC computational prediction followed by experimental validation. miR-2
CC regulates the proapoptotic genes reaper, grim and sickle, suggesting that
CC it may be involved in the control of apoptosis.
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..28
FT /accession="MIMAT0020780"
FT /product="dme-miR-2a-1-5p"
FT /evidence=not_experimental
FT miRNA 49..71
FT /accession="MIMAT0000106"
FT /product="dme-miR-2a-3p"
FT /evidence=experimental
FT /experiment="cloned [1,4], Northern [1,3], 454 [5-6],
FT Illumina [6]"
FT /similarity="MI0000117"
XX
SQ Sequence 76 BP; 15 A; 18 C; 21 G; 0 T; 22 other;
gcugggcucu caaagugguu gugaaaugca uuuccgcuuu gcgcggcaua ucacagccag 60
cuuugaugag cuuagc 76
//
ID dme-mir-2a-2 standard; RNA; DME; 72 BP.
XX
AC MI0000118;
XX
DE Drosophila melanogaster miR-2a-2 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 14691535.
RA Stark A, Brennecke J, Russell RB, Cohen SM;
RT "Identification of Drosophila MicroRNA targets";
RL PLoS Biol. 1:E60(2003).
XX
RN [3]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [4]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [5]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [6]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR RFAM; RF00047; mir-2.
DR TARGETS:PICTAR-FLY; dme-miR-2a; dme-miR-2a.
XX
CC Stark et al. [2] have identified targets for miR-2 in Drosophila using
CC computational prediction followed by experimental validation. miR-2
CC regulates the proapoptotic genes reaper, grim and sickle, suggesting that
CC it may be involved in the control of apoptosis.
XX
FH Key Location/Qualifiers
FH
FT miRNA 8..28
FT /accession="MIMAT0020781"
FT /product="dme-miR-2a-2-5p"
FT /evidence=not_experimental
FT miRNA 44..66
FT /accession="MIMAT0000106"
FT /product="dme-miR-2a-3p"
FT /evidence=experimental
FT /experiment="cloned [1,4], Northern [1,3], 454 [5-6],
FT Illumina [6]"
FT /similarity="MI0000118"
XX
SQ Sequence 72 BP; 21 A; 16 C; 16 G; 0 T; 19 other;
aucuaagccu caucaagugg uugugauaug gauacccaac gcauaucaca gccagcuuug 60
augagcuagg au 72
//
ID dme-mir-2b-1 standard; RNA; DME; 77 BP.
XX
AC MI0000119;
XX
DE Drosophila melanogaster miR-2b-1 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 14691535.
RA Stark A, Brennecke J, Russell RB, Cohen SM;
RT "Identification of Drosophila MicroRNA targets";
RL PLoS Biol. 1:E60(2003).
XX
RN [3]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [4]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [5]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [6]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR RFAM; RF00047; mir-2.
DR TARGETS:MIRTE; miR-2b; miR-2b.
DR TARGETS:PICTAR-FLY; dme-miR-2b; dme-miR-2b.
XX
CC Stark et al. [2] have identified targets for miR-2 in Drosophila using
CC computational prediction followed by experimental validation. miR-2
CC regulates the proapoptotic genes reaper, grim and sickle, suggesting that
CC it may be involved in the control of apoptosis.
XX
FH Key Location/Qualifiers
FH
FT miRNA 9..31
FT /accession="MIMAT0020782"
FT /product="dme-miR-2b-1-5p"
FT /evidence=not_experimental
FT miRNA 48..70
FT /accession="MIMAT0000107"
FT /product="dme-miR-2b-3p"
FT /evidence=experimental
FT /experiment="cloned [1,4], Northern [1,3], 454 [5-6],
FT Illumina [6]"
FT /similarity="MI0000119"
XX
SQ Sequence 77 BP; 20 A; 17 C; 18 G; 0 T; 22 other;
cuucaacugu cuucaaagug gcagugacau guugucaaca auauucauau cacagccagc 60
uuugaggagc guugcgg 77
//
ID dme-mir-2b-2 standard; RNA; DME; 83 BP.
XX
AC MI0000120;
XX
DE Drosophila melanogaster miR-2b-2 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 14691535.
RA Stark A, Brennecke J, Russell RB, Cohen SM;
RT "Identification of Drosophila MicroRNA targets";
RL PLoS Biol. 1:E60(2003).
XX
RN [3]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [4]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [5]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [6]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR RFAM; RF00047; mir-2.
DR MIRTE; miR-2b; miR-2b.
DR TARGETS:PICTAR-FLY; dme-miR-2b; dme-miR-2b.
XX
CC Stark et al. [2] have identified targets for miR-2 in Drosophila using
CC computational prediction followed by experimental validation. miR-2
CC regulates the proapoptotic genes reaper, grim and sickle, suggesting that
CC it may be involved in the control of apoptosis.
XX
FH Key Location/Qualifiers
FH
FT miRNA 9..31
FT /accession="MIMAT0020783"
FT /product="dme-miR-2b-2-5p"
FT /evidence=not_experimental
FT miRNA 54..76
FT /accession="MIMAT0000107"
FT /product="dme-miR-2b-3p"
FT /evidence=experimental
FT /experiment="cloned [1,4], Northern [1,3], 454 [5-6],
FT Illumina [6]"
FT /similarity="MI0000120"
XX
SQ Sequence 83 BP; 18 A; 16 C; 19 G; 0 T; 30 other;
uugugucauu cuucaaagug guugugaaau guuugccuuu uuaugccuau ucauaucaca 60
gccagcuuug aggagcgacg cga 83
//
ID dme-mir-3 standard; RNA; DME; 69 BP.
XX
AC MI0000121;
XX
DE Drosophila melanogaster miR-3 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [3]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [4]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [5]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-3; miR-3.
DR TARGETS:PICTAR-FLY; dme-miR-3; dme-miR-3.
XX
FH Key Location/Qualifiers
FH
FT miRNA 8..29
FT /accession="MIMAT0020784"
FT /product="dme-miR-3-5p"
FT /evidence=not_experimental
FT miRNA 43..64
FT /accession="MIMAT0000108"
FT /product="dme-miR-3-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1-3], 454 [4-5],
FT Illumina [5]"
FT /similarity="MI0000121"
XX
SQ Sequence 69 BP; 16 A; 15 C; 16 G; 0 T; 22 other;
gauccuggga ugcaucuugu gcaguuaugu uucaaucuca caucacuggg caaagugugu 60
cucaagauc 69
//
ID dme-mir-4 standard; RNA; DME; 81 BP.
XX
AC MI0000122;
XX
DE Drosophila melanogaster miR-4 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [3]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [4]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [5]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-4; miR-4.
DR TARGETS:PICTAR-FLY; dme-miR-4; dme-miR-4.
XX
FH Key Location/Qualifiers
FH
FT miRNA 14..37
FT /accession="MIMAT0020785"
FT /product="dme-miR-4-5p"
FT /evidence=not_experimental
FT miRNA 49..69
FT /accession="MIMAT0000109"
FT /product="dme-miR-4-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1-3], 454 [4-5],
FT Illumina [5]"
FT /similarity="MI0000122"
XX
SQ Sequence 81 BP; 17 A; 15 C; 19 G; 0 T; 30 other;
uugcaauuag uuucuuuggu cguccagccu uaggugauuu uuccggucau aaagcuagac 60
aaccauugaa guucguugug g 81
//
ID dme-mir-5 standard; RNA; DME; 69 BP.
XX
AC MI0000123;
XX
DE Drosophila melanogaster miR-5 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [3]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [4]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [5]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-5; miR-5.
DR TARGETS:PICTAR-FLY; dme-miR-5; dme-miR-5.
XX
FH Key Location/Qualifiers
FH
FT miRNA 5..27
FT /accession="MIMAT0000110"
FT /product="dme-miR-5-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1-2], 454 [4-5],
FT Illumina [5]"
FT /similarity="MI0000123"
FT miRNA 43..65
FT /accession="MIMAT0020786"
FT /product="dme-miR-5-3p"
FT /evidence=not_experimental
XX
SQ Sequence 69 BP; 20 A; 12 C; 13 G; 0 T; 24 other;
gcuaaaagga acgaucguug ugauaugagu uguuuccuaa cauaucacag ugauuuuccu 60
uuauaacgc 69
//
ID dme-mir-6-1 standard; RNA; DME; 82 BP.
XX
AC MI0000124;
XX
DE Drosophila melanogaster miR-6-1 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [3]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [4]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [5]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-6; miR-6.
DR TARGETS:PICTAR-FLY; dme-miR-6; dme-miR-6.
XX
FH Key Location/Qualifiers
FH
FT miRNA 11..32
FT /accession="MIMAT0020787"
FT /product="dme-miR-6-1-5p"
FT /evidence=not_experimental
FT miRNA 52..73
FT /accession="MIMAT0000111"
FT /product="dme-miR-6-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1-2], 454 [4],
FT Illumina [5]"
XX
SQ Sequence 82 BP; 23 A; 11 C; 16 G; 0 T; 32 other;
uuuaauguag agggaauagu ugcugugcug uaaguuaaua uaccauaucu auaucacagu 60
ggcuguucuu uuuguaccua aa 82
//
ID dme-mir-6-2 standard; RNA; DME; 74 BP.
XX
AC MI0000125;
XX
DE Drosophila melanogaster miR-6-2 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [3]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [4]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [5]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:PICTAR-FLY; dme-miR-6; dme-miR-6.
XX
FH Key Location/Qualifiers
FH
FT miRNA 8..30
FT /accession="MIMAT0020788"
FT /product="dme-miR-6-2-5p"
FT /evidence=not_experimental
FT miRNA 48..69
FT /accession="MIMAT0000111"
FT /product="dme-miR-6-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1-2], 454 [4],
FT Illumina [5]"
FT /similarity="MI0000125"
XX
SQ Sequence 74 BP; 20 A; 13 C; 14 G; 0 T; 27 other;
uaacccaagg gaacuucugc ugcugauaua uuauugaaaa acuacuauau cacaguggcu 60
guucuuuuug guug 74
//
ID dme-mir-6-3 standard; RNA; DME; 80 BP.
XX
AC MI0000126;
XX
DE Drosophila melanogaster miR-6-3 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [3]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [4]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [5]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:PICTAR-FLY; dme-miR-6; dme-miR-6.
XX
FH Key Location/Qualifiers
FH
FT miRNA 9..31
FT /accession="MIMAT0020789"
FT /product="dme-miR-6-3-5p"
FT /evidence=not_experimental
FT miRNA 53..74
FT /accession="MIMAT0000111"
FT /product="dme-miR-6-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1-2], 454 [4],
FT Illumina [5]"
FT /similarity="MI0000126"
XX
SQ Sequence 80 BP; 22 A; 11 C; 18 G; 0 T; 29 other;
caaaaagaag ggaacgguug cugaugaugu aguuugaaac ucucacaauu uauaucacag 60
uggcuguucu uuuuuguuug 80
//
ID dme-mir-7 standard; RNA; DME; 88 BP.
XX
AC MI0000127;
XX
DE Drosophila melanogaster miR-7 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 14691535.
RA Stark A, Brennecke J, Russell RB, Cohen SM;
RT "Identification of Drosophila MicroRNA targets";
RL PLoS Biol. 1:E60(2003).
XX
RN [3]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [4]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [5]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [6]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR RFAM; RF00053; mir-7.
DR TARGETS:MIRTE; miR-7; miR-7.
DR TARGETS:PICTAR-FLY; dme-miR-7; dme-miR-7.
DR ENTREZGENE; 3772237; mir-7.
XX
CC Stark et al. [2] have identified targets for miR-7 in Drosophila using
CC computational prediction followed by experimental validation. miR-7
CC regulates a family of Notch targets including the Enhancer of split and
CC Bearded complex genes Tom and m4, and the basic helix-loop-helix
CC transcriptional repressors HLHm3 and hairy.
XX
FH Key Location/Qualifiers
FH
FT miRNA 15..37
FT /accession="MIMAT0000112"
FT /product="dme-miR-7-5p"
FT /evidence=experimental
FT /experiment="cloned [1,4], Northern [1,3-4], 454 [5-6],
FT Illumina [6]"
FT /similarity="MI0000127"
FT miRNA 55..76
FT /accession="MIMAT0020790"
FT /product="dme-miR-7-3p"
FT /evidence=not_experimental
XX
SQ Sequence 88 BP; 19 A; 14 C; 20 G; 0 T; 35 other;
gagugcauuc cguauggaag acuagugauu uuguuguuug gucuuuggua auaacaauaa 60
aucccuuguc uucuuacggc gugcauuu 88
//
ID dme-mir-8 standard; RNA; DME; 87 BP.
XX
AC MI0000128;
XX
DE Drosophila melanogaster miR-8 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [3]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [4]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [5]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR ENTREZGENE; 3771764; mir-8.
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..37
FT /accession="MIMAT0020791"
FT /product="dme-miR-8-5p"
FT /evidence=not_experimental
FT miRNA 53..75
FT /accession="MIMAT0000113"
FT /product="dme-miR-8-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1-3], 454 [4-5],
FT Illumina [5]"
FT /similarity="MI0000128"
XX
SQ Sequence 87 BP; 22 A; 20 C; 16 G; 0 T; 29 other;
aaggacaucu guucacaucu uaccgggcag cauuagaucc uuuuuauaac ucuaauacug 60
ucagguaaag augucguccg uguccuu 87
//
ID dme-mir-9a standard; RNA; DME; 78 BP.
XX
AC MI0000129;
XX
DE Drosophila melanogaster miR-9a stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [3]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [4]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [5]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-9a; miR-9a.
DR TARGETS:PICTAR-FLY; dme-miR-9a; dme-miR-9a.
XX
FH Key Location/Qualifiers
FH
FT miRNA 10..32
FT /accession="MIMAT0000114"
FT /product="dme-miR-9a-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1-3], 454 [4-5],
FT Illumina [5]"
FT /similarity="MI0000129"
FT miRNA 49..70
FT /accession="MIMAT0020792"
FT /product="dme-miR-9a-3p"
FT /evidence=not_experimental
XX
SQ Sequence 78 BP; 23 A; 11 C; 16 G; 0 T; 28 other;
gcuauguugu cuuugguuau cuagcuguau gagugauaaa uaacgucaua aagcuagcuu 60
accgaaguua auauuagc 78
//
ID dme-mir-10 standard; RNA; DME; 77 BP.
XX
AC MI0000130;
XX
DE Drosophila melanogaster miR-10 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [3]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [4]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [5]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR RFAM; RF00104; mir-10.
DR TARGETS:MIRTE; miR-10; miR-10.
DR TARGETS:PICTAR-FLY; dme-miR-10; dme-miR-10.
XX
CC The first cloning experiments identified the mature miR-10 from the 5' arm
CC of the D. melanogaster precursor [1,3]. High-throughput sequencing later
CC showed that the sequence from the 3' arm dominates [4-5].
XX
FH Key Location/Qualifiers
FH
FT miRNA 9..30
FT /accession="MIMAT0000115"
FT /product="dme-miR-10-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1-3], 454 [4-5],
FT Illumina [5]"
FT miRNA 49..71
FT /accession="MIMAT0012531"
FT /product="dme-miR-10-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1-3], 454 [4-5],
FT Illumina [5]"
XX
SQ Sequence 77 BP; 18 A; 14 C; 18 G; 0 T; 27 other;
ccacgucuac ccuguagauc cgaauuuguu uuauacuagc uuuaaggaca aauucgguuc 60
uagagagguu ugugugg 77
//
ID dme-mir-11 standard; RNA; DME; 75 BP.
XX
AC MI0000131;
XX
DE Drosophila melanogaster miR-11 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [3]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [4]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [5]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-11; miR-11.
DR TARGETS:PICTAR-FLY; dme-miR-11; dme-miR-11.
XX
FH Key Location/Qualifiers
FH
FT miRNA 9..30
FT /accession="MIMAT0020793"
FT /product="dme-miR-11-5p"
FT /evidence=not_experimental
FT miRNA 48..68
FT /accession="MIMAT0000116"
FT /product="dme-miR-11-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1-2], 454 [4-5],
FT Illumina [5]"
FT /similarity="MI0000131"
XX
SQ Sequence 75 BP; 16 A; 20 C; 17 G; 0 T; 22 other;
gcacuuguca agaacuuucu cugugacccg cguguacuua aaagccgcau cacagucuga 60
guucuugcug agugc 75
//
ID dme-mir-12 standard; RNA; DME; 74 BP.
XX
AC MI0000132;
XX
DE Drosophila melanogaster miR-12 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [3]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [4]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [5]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-12; miR-12.
DR TARGETS:PICTAR-FLY; dme-miR-12; dme-miR-12.
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..29
FT /accession="MIMAT0000117"
FT /product="dme-miR-12-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1-2], 454 [4-5],
FT Illumina [5]"
FT /similarity="MI0000132"
FT miRNA 49..70
FT /accession="MIMAT0020794"
FT /product="dme-miR-12-3p"
FT /evidence=not_experimental
XX
SQ Sequence 74 BP; 20 A; 17 C; 15 G; 0 T; 22 other;
uacgguugag uauuacauca gguacuggug ugccuuaaau ccaacaacca guacuuaugu 60
cauacuacgc cgug 74
//
ID dme-mir-13a standard; RNA; DME; 75 BP.
XX
AC MI0000133;
XX
DE Drosophila melanogaster miR-13a stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [3]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [4]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR RFAM; RF00047; mir-2.
DR TARGETS:MIRTE; miR-13a; miR-13a.
DR TARGETS:PICTAR-FLY; dme-miR-13a; dme-miR-13a.
XX
FH Key Location/Qualifiers
FH
FT miRNA 8..29
FT /accession="MIMAT0020795"
FT /product="dme-miR-13a-5p"
FT /evidence=not_experimental
FT miRNA 48..69
FT /accession="MIMAT0000118"
FT /product="dme-miR-13a-3p"
FT /evidence=experimental
FT /experiment="cloned [1], Northern [1-2], 454 [3-4],
FT Illumina [4]"
FT /similarity="MI0000133"
XX
SQ Sequence 75 BP; 20 A; 15 C; 14 G; 0 T; 26 other;
uacguaacuc cucaaagggu ugugaaaugu cgacuauuau cuacucauau cacagccauu 60
uugaugaguu ucgug 75
//
ID dme-mir-13b-1 standard; RNA; DME; 68 BP.
XX
AC MI0000134;
XX
DE Drosophila melanogaster miR-13b-1 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [3]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [4]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [5]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR RFAM; RF00047; mir-2.
DR TARGETS:MIRTE; miR-13b; miR-13b.
DR TARGETS:PICTAR-FLY; dme-miR-13b; dme-miR-13b.
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..30
FT /accession="MIMAT0020796"
FT /product="dme-miR-13b-1-5p"
FT /evidence=not_experimental
FT miRNA 43..64
FT /accession="MIMAT0000119"
FT /product="dme-miR-13b-3p"
FT /evidence=experimental
FT /experiment="Northern [1-2], cloned [3], 454 [4-5],
FT Illumina [5]"
FT /similarity="MI0000134"
XX
SQ Sequence 68 BP; 19 A; 12 C; 12 G; 0 T; 25 other;
ccaugucguu aaaauguuug ugaacuuaug uauucacaau cauaucacag ccauuuugac 60
gaguuugg 68
//
ID dme-mir-13b-2 standard; RNA; DME; 70 BP.
XX
AC MI0000135;
XX
DE Drosophila melanogaster miR-13b-2 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [3]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [4]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [5]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR RFAM; RF00047; mir-2.
DR TARGETS:PICTAR-FLY; dme-miR-13b; dme-miR-13b.
XX
FH Key Location/Qualifiers
FH
FT miRNA 8..31
FT /accession="MIMAT0020797"
FT /product="dme-miR-13b-2-5p"
FT /evidence=not_experimental
FT miRNA 46..67
FT /accession="MIMAT0000119"
FT /product="dme-miR-13b-3p"
FT /evidence=experimental
FT /experiment="Northern [1-2], cloned [3], 454 [4-5],
FT Illumina [5]"
FT /similarity="MI0000135"
XX
SQ Sequence 70 BP; 19 A; 12 C; 15 G; 0 T; 24 other;
uauuaacgcg ucaaaaugac ugugagcuau guggauuuga cuucauauca cagccauuuu 60
gacgaguuug 70
//
ID dme-mir-14 standard; RNA; DME; 63 BP.
XX
AC MI0000136;
XX
DE Drosophila melanogaster miR-14 stem-loop
XX
RN [1]
RX PUBMED; 11679670.
RA Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T;
RT "Identification of novel genes coding for small expressed RNAs";
RL Science. 294:853-858(2001).
XX
RN [2]
RX PUBMED; 12725740.
RA Xu P, Vernooy SY, Guo M, Hay BA;
RT "The Drosophila microRNA Mir-14 suppresses cell death and is required for
RT normal fat metabolism";
RL Curr Biol. 13:790-795(2003).
XX
RN [3]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [4]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [5]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [6]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-14; miR-14.
DR TARGETS:PICTAR-FLY; dme-miR-14; dme-miR-14.
XX
CC miR-14 has been reported to act as a cell death repressor and regulator of
CC fat metabolism [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 4..25
FT /accession="MIMAT0020798"
FT /product="dme-miR-14-5p"
FT /evidence=not_experimental
FT miRNA 41..62
FT /accession="MIMAT0000120"
FT /product="dme-miR-14-3p"
FT /evidence=experimental
FT /experiment="cloned [1,4], Northern [3], 454 [5-6],
FT Illumina [6]"
FT /similarity="MI0000136"
XX
SQ Sequence 63 BP; 13 A; 13 C; 15 G; 0 T; 22 other;
ugugggagcg agacggggac ucacugugcu uauuaaauag ucagucuuuu ucucucuccu 60
aua 63
//
ID mmu-let-7g standard; RNA; MMU; 88 BP.
XX
AC MI0000137;
XX
DE Mus musculus let-7g stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [3]
RX PUBMED; 16766679.
RA Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N,
RA Imai H;
RT "Identification and characterization of two novel classes of small RNAs in
RT the mouse germline: retrotransposon-derived siRNAs in oocytes and germline
RT small RNAs in testes";
RL Genes Dev. 20:1732-1743(2006).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [6]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR RFAM; RF00027; let-7.
DR MGI; 2676800; Mirlet7g.
DR ENTREZGENE; 387249; Mirlet7g.
XX
CC The mature sequence reported in [1] has a 3' terminal A residue, which is
CC incompatible with the reported precursor sequence from [1] and in this
CC entry. The mature sequence shown here represents the most commonly cloned
CC form from large-scale cloning studies [4].
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..28
FT /accession="MIMAT0000121"
FT /product="mmu-let-7g-5p"
FT /evidence=experimental
FT /experiment="cloned [1-4], Illumina [5-6]"
FT miRNA 63..84
FT /accession="MIMAT0004519"
FT /product="mmu-let-7g-3p"
FT /evidence=experimental
FT /experiment="cloned [4], Illumina [5-6]"
XX
SQ Sequence 88 BP; 21 A; 20 C; 26 G; 0 T; 21 other;
ccaggcugag guaguaguuu guacaguuug agggucuaug auaccacccg guacaggaga 60
uaacuguaca ggccacugcc uugccagg 88
//
ID mmu-let-7i standard; RNA; MMU; 85 BP.
XX
AC MI0000138;
XX
DE Mus musculus let-7i stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [3]
RX PUBMED; 16766679.
RA Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N,
RA Imai H;
RT "Identification and characterization of two novel classes of small RNAs in
RT the mouse germline: retrotransposon-derived siRNAs in oocytes and germline
RT small RNAs in testes";
RL Genes Dev. 20:1732-1743(2006).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [6]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR RFAM; RF00027; let-7.
DR MGI; 2676802; Mirlet7i.
DR ENTREZGENE; 387251; Mirlet7i.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [4].
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..27
FT /accession="MIMAT0000122"
FT /product="mmu-let-7i-5p"
FT /evidence=experimental
FT /experiment="cloned [1-4], Illumina [5-6]"
FT miRNA 62..83
FT /accession="MIMAT0004520"
FT /product="mmu-let-7i-3p"
FT /evidence=experimental
FT /experiment="cloned [4], Illumina [5-6]"
XX
SQ Sequence 85 BP; 13 A; 17 C; 29 G; 0 T; 26 other;
cuggcugagg uaguaguuug ugcuguuggu cggguuguga cauugcccgc uguggagaua 60
acugcgcaag cuacugccuu gcuag 85
//
ID mmu-mir-1a-1 standard; RNA; MMU; 77 BP.
XX
AC MI0000139;
XX
DE Mus musculus miR-1a-1 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR RFAM; RF00103; mir-1.
DR MGI; 2676869; Mir1-1.
DR ENTREZGENE; 387136; Mir1a-1.
XX
CC Lagos-Quintana et al. [1] reported the cloning of miR-1b, miR-1c and
CC miR-1d. The mature processed miR sequences are identical apart from the
CC 3' residues (A in mir-1b, C in mir-1c and UU in mir-1d). The 3' residues
CC of both miR-1b and miR-1c conflict with the predicted stem-loop precursor
CC sequence shown here and these sequences are not found in current
CC assemblies of human and mouse genomes. It is suggested that polyA
CC polymerase may add 1-3 nts to the 3' end of the mature transcript (Tom
CC Tuschl, pers. comm.). The common 21 nts of the 3 reported miR sequences
CC have been rationalised here and named miR-1. There are 2 pairs of
CC orthologous putative hairpin precursor structures named mir-1-1 (human
CC MIR:MI0000651, mouse MIR:MI0000139), and mir-1-2 (human MIR:MI0000437,
CC mouse MIR:MI0000652). The mature sequence shown here represents the most
CC commonly cloned form from large-scale cloning studies [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 10..32
FT /accession="MIMAT0016979"
FT /product="mmu-miR-1a-1-5p"
FT /evidence=experimental
FT /experiment="Illumina [3]"
FT miRNA 49..70
FT /accession="MIMAT0000123"
FT /product="mmu-miR-1a-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Illumina [3]"
XX
SQ Sequence 77 BP; 23 A; 14 C; 16 G; 0 T; 24 other;
gcuugggaca cauacuucuu uauaugccca uaugaaccug cuaagcuaug gaauguaaag 60
aaguauguau uucaggc 77
//
ID mmu-mir-15b standard; RNA; MMU; 64 BP.
XX
AC MI0000140;
XX
DE Mus musculus miR-15b stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [3]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
XX
RN [4]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [5]
RX PUBMED; 16766679.
RA Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N,
RA Imai H;
RT "Identification and characterization of two novel classes of small RNAs in
RT the mouse germline: retrotransposon-derived siRNAs in oocytes and germline
RT small RNAs in testes";
RL Genes Dev. 20:1732-1743(2006).
XX
RN [6]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [7]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [8]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676842; Mir15b.
DR ENTREZGENE; 387175; Mir15b.
XX
FH Key Location/Qualifiers
FH
FT miRNA 4..25
FT /accession="MIMAT0000124"
FT /product="mmu-miR-15b-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2,4-6], Illumina [7-8]"
FT miRNA 42..63
FT /accession="MIMAT0004521"
FT /product="mmu-miR-15b-3p"
FT /evidence=experimental
FT /experiment="cloned [6], Illumina [7-8]"
XX
SQ Sequence 64 BP; 18 A; 14 C; 12 G; 0 T; 20 other;
cuguagcagc acaucauggu uuacauacua cagucaagau gcgaaucauu auuugcugcu 60
cuag 64
//
ID mmu-mir-23b standard; RNA; MMU; 74 BP.
XX
AC MI0000141;
XX
DE Mus musculus miR-23b stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
XX
RN [3]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [6]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676898; Mir23b.
DR ENTREZGENE; 387217; Mir23b.
XX
FH Key Location/Qualifiers
FH
FT miRNA 9..29
FT /accession="MIMAT0016980"
FT /product="mmu-miR-23b-5p"
FT /evidence=experimental
FT /experiment="Illumina [6]"
FT miRNA 46..66
FT /accession="MIMAT0000125"
FT /product="mmu-miR-23b-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3-4], Illumina [5-6]"
XX
SQ Sequence 74 BP; 17 A; 17 C; 19 G; 0 T; 21 other;
ggcugcuugg guuccuggca ugcugauuug ugacuugaga uuaaaaucac auugccaggg 60
auuaccacgc aacc 74
//
ID mmu-mir-27b standard; RNA; MMU; 73 BP.
XX
AC MI0000142;
XX
DE Mus musculus miR-27b stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [3]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
XX
RN [4]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [5]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [6]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [7]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676903; Mir27b.
DR ENTREZGENE; 387221; Mir27b.
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..28
FT /accession="MIMAT0004522"
FT /product="mmu-miR-27b-5p"
FT /evidence=experimental
FT /experiment="cloned [5], Illumina [6-7]"
FT miRNA 49..69
FT /accession="MIMAT0000126"
FT /product="mmu-miR-27b-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3-5], Illumina [6-7]"
XX
SQ Sequence 73 BP; 14 A; 14 C; 21 G; 0 T; 24 other;
aggugcagag cuuagcugau uggugaacag ugauugguuu ccgcuuuguu cacaguggcu 60
aaguucugca ccu 73
//
ID mmu-mir-29b-1 standard; RNA; MMU; 71 BP.
XX
AC MI0000143;
XX
DE Mus musculus miR-29b-1 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [3]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [4]
RX PUBMED; 15634332.
RA Weber MJ;
RT "New human and mouse microRNA genes found by homology search";
RL FEBS J. 272:59-73(2005).
XX
RN [5]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [6]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [7]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR RFAM; RF00074; mir-29.
DR MGI; 2676905; Mir29b-1.
DR ENTREZGENE; 387223; Mir29b-1.
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..27
FT /accession="MIMAT0004523"
FT /product="mmu-miR-29b-1-5p"
FT /evidence=experimental
FT /experiment="cloned [5], Illumina [6-7]"
FT miRNA 47..69
FT /accession="MIMAT0000127"
FT /product="mmu-miR-29b-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3,5], Illumina [6-7]"
XX
SQ Sequence 71 BP; 19 A; 8 C; 17 G; 0 T; 27 other;
aggaagcugg uuucauaugg ugguuuagau uuaaauagug auugucuagc accauuugaa 60
aucaguguuc u 71
//
ID mmu-mir-30a standard; RNA; MMU; 71 BP.
XX
AC MI0000144;
XX
DE Mus musculus miR-30a stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [3]
RX PUBMED; 16766679.
RA Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N,
RA Imai H;
RT "Identification and characterization of two novel classes of small RNAs in
RT the mouse germline: retrotransposon-derived siRNAs in oocytes and germline
RT small RNAs in testes";
RL Genes Dev. 20:1732-1743(2006).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [6]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676907; Mir30a.
DR ENTREZGENE; 387225; Mir30a.
XX
CC Landgraf et al. confirm that the 5' mature miRNA product is the
CC predominant one [4].
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..27
FT /accession="MIMAT0000128"
FT /product="mmu-miR-30a-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2,4], Illumina [5-6]"
FT miRNA 47..68
FT /accession="MIMAT0000129"
FT /product="mmu-miR-30a-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3-4], Illumina [5-6]"
XX
SQ Sequence 71 BP; 17 A; 17 C; 20 G; 0 T; 17 other;
gcgacuguaa acauccucga cuggaagcug ugaagccaca aaugggcuuu cagucggaug 60
uuugcagcug c 71
//
ID mmu-mir-30b standard; RNA; MMU; 96 BP.
XX
AC MI0000145;
XX
DE Mus musculus miR-30b stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [5]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676908; Mir30b.
DR ENTREZGENE; 387226; Mir30b.
XX
FH Key Location/Qualifiers
FH
FT miRNA 21..42
FT /accession="MIMAT0000130"
FT /product="mmu-miR-30b-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Illumina [4-5]"
FT miRNA 59..80
FT /accession="MIMAT0004524"
FT /product="mmu-miR-30b-3p"
FT /evidence=experimental
FT /experiment="cloned [3], Illumina [4-5]"
XX
SQ Sequence 96 BP; 22 A; 20 C; 23 G; 0 T; 31 other;
cuaagccaag uuucaguuca uguaaacauc cuacacucag cugucauaca ugcguuggcu 60
gggaugugga uguuuacguc agcugucuug gaguau 96
//
ID mmu-mir-99a standard; RNA; MMU; 65 BP.
XX
AC MI0000146;
XX
DE Mus musculus miR-99a stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 16766679.
RA Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N,
RA Imai H;
RT "Identification and characterization of two novel classes of small RNAs in
RT the mouse germline: retrotransposon-derived siRNAs in oocytes and germline
RT small RNAs in testes";
RL Genes Dev. 20:1732-1743(2006).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [5]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676912; Mir99a.
DR ENTREZGENE; 387229; Mir99a.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [3]. The 5' end of the miRNA may be
CC offset with respect to previous annotations.
XX
FH Key Location/Qualifiers
FH
FT miRNA 5..26
FT /accession="MIMAT0000131"
FT /product="mmu-miR-99a-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Illumina [4-5]"
FT miRNA 42..62
FT /accession="MIMAT0016981"
FT /product="mmu-miR-99a-3p"
FT /evidence=experimental
FT /experiment="Illumina [5]"
XX
SQ Sequence 65 BP; 13 A; 15 C; 19 G; 0 T; 18 other;
cauaaacccg uagauccgau cuugugguga aguggaccgc gcaagcucgu uucuaugggu 60
cugug 65
//
ID mmu-mir-99b standard; RNA; MMU; 70 BP.
XX
AC MI0000147;
XX
DE Mus musculus miR-99b stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [3]
RX PUBMED; 16766679.
RA Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N,
RA Imai H;
RT "Identification and characterization of two novel classes of small RNAs in
RT the mouse germline: retrotransposon-derived siRNAs in oocytes and germline
RT small RNAs in testes";
RL Genes Dev. 20:1732-1743(2006).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [6]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676913; Mir99b.
DR ENTREZGENE; 387230; Mir99b.
XX
CC Expression of this miRNA in mouse was independently verified in the brain
CC [1], embryonic stem cells [2] and testes [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..28
FT /accession="MIMAT0000132"
FT /product="mmu-miR-99b-5p"
FT /evidence=experimental
FT /experiment="cloned [1-4], Illumina [5-6]"
FT miRNA 45..66
FT /accession="MIMAT0004525"
FT /product="mmu-miR-99b-3p"
FT /evidence=experimental
FT /experiment="cloned [4], Illumina [5-6]"
XX
SQ Sequence 70 BP; 10 A; 26 C; 21 G; 0 T; 13 other;
ggcacccacc cguagaaccg accuugcggg gccuucgccg cacacaagcu cgugucugug 60
gguccguguc 70
//
ID mmu-mir-101a standard; RNA; MMU; 83 BP.
XX
AC MI0000148;
XX
DE Mus musculus miR-101a stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [5]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676803; Mir101a.
DR ENTREZGENE; 387143; Mir101a.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 14..35
FT /accession="MIMAT0004526"
FT /product="mmu-miR-101a-5p"
FT /evidence=experimental
FT /experiment="cloned [3], Illumina [4-5]"
FT miRNA 51..71
FT /accession="MIMAT0000133"
FT /product="mmu-miR-101a-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Illumina [4-5]"
XX
SQ Sequence 83 BP; 21 A; 19 C; 22 G; 0 T; 21 other;
aggcugcccu ggcucaguua ucacagugcu gaugcugucc auucuaaagg uacaguacug 60
ugauaacuga aggauggcag cca 83
//
ID mmu-mir-124-3 standard; RNA; MMU; 68 BP.
XX
AC MI0000150;
XX
DE Mus musculus miR-124-3 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [3]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [6]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 3618704; Mirn124a-3.
DR ENTREZGENE; 723951; Mir124a-3.
XX
CC miR-124 was cloned from mouse brain [1] and embryonic stem cells [2] by
CC independent groups. There are 3 predicted precursor hairpin sequences:
CC mir-124-1 (MIR:MI0000716) on chromosome 14, mir-124-2 (MIR:MI0000717) on
CC chromosome 3, and mir-124-3 (previously known as miR-124a here,
CC MIR:MI0000150) on chromosome 2. All have closely related predicted human
CC homologues (MIR:MI0000443, MIR:MI0000444 and MIR:MI0000445).
CC Lagos-Quintana et al. also report a mature miRNA sequence miR-124b, with a
CC G insertion at position 12 [1]. miR-124b is not found in either the mouse
CC or human genome assemblies.
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..27
FT /accession="MIMAT0004527"
FT /product="mmu-miR-124-5p"
FT /evidence=experimental
FT /experiment="cloned [4], Illumina [5-6]"
FT miRNA 44..63
FT /accession="MIMAT0000134"
FT /product="mmu-miR-124-3p"
FT /evidence=experimental
FT /experiment="cloned [1-4], Illumina [5-6]"
XX
SQ Sequence 68 BP; 18 A; 15 C; 17 G; 0 T; 18 other;
cucugcgugu ucacagcgga ccuugauuua augucuauac aauuaaggca cgcggugaau 60
gccaagag 68
//
ID mmu-mir-125a standard; RNA; MMU; 68 BP.
XX
AC MI0000151;
XX
DE Mus musculus miR-125a stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676809; Mir125a.
DR ENTREZGENE; 387235; Mir125a.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..29
FT /accession="MIMAT0000135"
FT /product="mmu-miR-125a-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Illumina [3-4]"
FT miRNA 44..65
FT /accession="MIMAT0004528"
FT /product="mmu-miR-125a-3p"
FT /evidence=experimental
FT /experiment="cloned [2], Illumina [3-4]"
XX
SQ Sequence 68 BP; 11 A; 17 C; 24 G; 0 T; 16 other;
cugggucccu gagacccuuu aaccugugag gacguccagg gucacaggug agguucuugg 60
gagccugg 68
//
ID mmu-mir-125b-2 standard; RNA; MMU; 71 BP.
XX
AC MI0000152;
XX
DE Mus musculus miR-125b-2 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 15634332.
RA Weber MJ;
RT "New human and mouse microRNA genes found by homology search";
RL FEBS J. 272:59-73(2005).
XX
RN [3]
RX PUBMED; 16766679.
RA Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N,
RA Imai H;
RT "Identification and characterization of two novel classes of small RNAs in
RT the mouse germline: retrotransposon-derived siRNAs in oocytes and germline
RT small RNAs in testes";
RL Genes Dev. 20:1732-1743(2006).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [6]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR RFAM; RF00052; lin-4.
DR MGI; 3618706; Mir125b-2.
DR ENTREZGENE; 723952; Mir125b-2.
XX
CC Mouse miR-125b was cloned from mouse brain tissues in [1]. There are 2
CC predicted hairpin precursor structures in the mouse genome, each has a
CC closely related human homologue [2] (mir-125b-1, MIR:MI0000725;
CC mir-125b-2, MIR:MI0000152; the latter was previously named mir-125b here).
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..28
FT /accession="MIMAT0000136"
FT /product="mmu-miR-125b-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3-4], Illumina [5-6]"
FT miRNA 46..67
FT /accession="MIMAT0004529"
FT /product="mmu-miR-125b-2-3p"
FT /evidence=experimental
FT /experiment="cloned [4], Illumina [5-6]"
XX
SQ Sequence 71 BP; 17 A; 17 C; 17 G; 0 T; 20 other;
gccuaguccc ugagacccua acuugugagg uauuuuagua acaucacaag ucagguucuu 60
gggaccuagg c 71
//
ID mmu-mir-126a standard; RNA; MMU; 73 BP.
XX
AC MI0000153;
XX
DE Mus musculus miR-126a stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [3]
RX PUBMED; 16766679.
RA Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N,
RA Imai H;
RT "Identification and characterization of two novel classes of small RNAs in
RT the mouse germline: retrotransposon-derived siRNAs in oocytes and germline
RT small RNAs in testes";
RL Genes Dev. 20:1732-1743(2006).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [6]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676811; Mir126.
DR ENTREZGENE; 387145; Mir126.
XX
CC miR-123 identified in [1] was later found to originate from the same
CC precursor as miR-126 and was hence renamed miR-126-5p.
XX
FH Key Location/Qualifiers
FH
FT miRNA 9..29
FT /accession="MIMAT0000137"
FT /product="mmu-miR-126a-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2,4], Illumina [5-6]"
FT miRNA 46..67
FT /accession="MIMAT0000138"
FT /product="mmu-miR-126a-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3-4], Illumina [5-6]"
XX
SQ Sequence 73 BP; 19 A; 17 C; 16 G; 0 T; 21 other;
ugacagcaca uuauuacuuu ugguacgcgc ugugacacuu caaacucgua ccgugaguaa 60
uaaugcgcgg uca 73
//
ID mmu-mir-127 standard; RNA; MMU; 70 BP.
XX
AC MI0000154;
XX
DE Mus musculus miR-127 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [3]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [4]
RX PUBMED; 15854907.
RA Davis E, Caiment F, Tordoir X, Cavaille J, Ferguson-Smith A, Cockett N,
RA Georges M, Charlier C;
RT "RNAi-mediated allelic trans-interaction at the imprinted Rtl1/Peg11
RT locus";
RL Curr Biol. 15:743-749(2005).
XX
RN [5]
RX PUBMED; 16766679.
RA Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N,
RA Imai H;
RT "Identification and characterization of two novel classes of small RNAs in
RT the mouse germline: retrotransposon-derived siRNAs in oocytes and germline
RT small RNAs in testes";
RL Genes Dev. 20:1732-1743(2006).
XX
RN [6]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [7]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [8]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676812; Mir127.
DR ENTREZGENE; 387146; Mir127.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [6].
XX
FH Key Location/Qualifiers
FH
FT miRNA 9..30
FT /accession="MIMAT0004530"
FT /product="mmu-miR-127-5p"
FT /evidence=experimental
FT /experiment="cloned [6], Illumina [7-8]"
FT miRNA 43..64
FT /accession="MIMAT0000139"
FT /product="mmu-miR-127-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3,5-6], PCR [4], Illumina [7-8]"
XX
SQ Sequence 70 BP; 14 A; 18 C; 22 G; 0 T; 16 other;
ccagccugcu gaagcucaga gggcucugau ucagaaagau caucggaucc gucugagcuu 60
ggcuggucgg 70
//
ID mmu-mir-128-1 standard; RNA; MMU; 70 BP.
XX
AC MI0000155;
XX
DE Mus musculus miR-128-1 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [5]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676813; Mir128-1.
DR ENTREZGENE; 387147; Mir128-1.
XX
CC The most commonly cloned mature sequences derived from the previously
CC annotated mir-128a and mir-128b were shown by Landgraf et al to be
CC identical [3]. The sequences are therefore renamed mir-128-1 and
CC mir-128-2.
XX
FH Key Location/Qualifiers
FH
FT miRNA 9..29
FT /accession="MIMAT0016982"
FT /product="mmu-miR-128-1-5p"
FT /evidence=experimental
FT /experiment="Illumina [5]"
FT miRNA 44..64
FT /accession="MIMAT0000140"
FT /product="mmu-miR-128-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Illumina [4-5]"
XX
SQ Sequence 70 BP; 12 A; 16 C; 19 G; 0 T; 23 other;
guuggauucg gggccguagc acugucugag agguuuacau uucucacagu gaaccggucu 60
cuuuuucagc 70
//
ID mmu-mir-130a standard; RNA; MMU; 64 BP.
XX
AC MI0000156;
XX
DE Mus musculus miR-130a stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [3]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
XX
RN [4]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [5]
RX PUBMED; 16766679.
RA Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N,
RA Imai H;
RT "Identification and characterization of two novel classes of small RNAs in
RT the mouse germline: retrotransposon-derived siRNAs in oocytes and germline
RT small RNAs in testes";
RL Genes Dev. 20:1732-1743(2006).
XX
RN [6]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [7]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [8]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676816; Mir130a.
DR ENTREZGENE; 387149; Mir130a.
XX
CC This sequence was named miR-130 in reference [1], but is renamed here to
CC avoid confusion with miR-130b (MIR:MI0000408).
XX
FH Key Location/Qualifiers
FH
FT miRNA 3..24
FT /accession="MIMAT0016983"
FT /product="mmu-miR-130a-5p"
FT /evidence=experimental
FT /experiment="Illumina [8]"
FT miRNA 42..63
FT /accession="MIMAT0000141"
FT /product="mmu-miR-130a-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2,4-6], Northern [2], Illumina [7]"
XX
SQ Sequence 64 BP; 16 A; 14 C; 15 G; 0 T; 19 other;
gagcucuuuu cacauugugc uacugucuaa cguguaccga gcagugcaau guuaaaaggg 60
cauc 64
//
ID mmu-mir-9-2 standard; RNA; MMU; 72 BP.
XX
AC MI0000157;
XX
DE Mus musculus miR-9-2 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [3]
RX PUBMED; 15634332.
RA Weber MJ;
RT "New human and mouse microRNA genes found by homology search";
RL FEBS J. 272:59-73(2005).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [6]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 3619442; Mir9-2.
DR ENTREZGENE; 723967; Mir9-2.
XX
FH Key Location/Qualifiers
FH
FT miRNA 8..30
FT /accession="MIMAT0000142"
FT /product="mmu-miR-9-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2,4], Illumina [5-6]"
FT miRNA 45..66
FT /accession="MIMAT0000143"
FT /product="mmu-miR-9-3p"
FT /evidence=experimental
FT /experiment="cloned [1,4], Illumina [5-6]"
XX
SQ Sequence 72 BP; 22 A; 9 C; 15 G; 0 T; 26 other;
guuguuaucu uugguuaucu agcuguauga guguauuggu cuucauaaag cuagauaacc 60
gaaaguaaaa ac 72
//
ID mmu-mir-132 standard; RNA; MMU; 66 BP.
XX
AC MI0000158;
XX
DE Mus musculus miR-132 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20668074.
RA Zhu JY, Strehle M, Frohn A, Kremmer E, Hofig KP, Meister G, Adler H;
RT "Identification and analysis of expression of novel microRNAs of murine
RT gammaherpesvirus 68";
RL J Virol. 84:10266-10275(2010).
XX
RN [5]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676817; Mir132.
DR ENTREZGENE; 387150; Mir132.
XX
FH Key Location/Qualifiers
FH
FT miRNA 5..26
FT /accession="MIMAT0016984"
FT /product="mmu-miR-132-5p"
FT /evidence=experimental
FT /experiment="454 [4], Illumina [5]"
FT miRNA 42..63
FT /accession="MIMAT0000144"
FT /product="mmu-miR-132-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Illumina [3,5]"
XX
SQ Sequence 66 BP; 13 A; 17 C; 21 G; 0 T; 15 other;
gggcaaccgu ggcuuucgau uguuacugug ggaaccggag guaacagucu acagccaugg 60
ucgccc 66
//
ID mmu-mir-133a-1 standard; RNA; MMU; 68 BP.
XX
AC MI0000159;
XX
DE Mus musculus miR-133a-1 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 16582102.
RA Mineno J, Okamoto S, Ando T, Sato M, Chono H, Izu H, Takayama M, Asada K,
RA Mirochnitchenko O, Inouye M, Kato I;
RT "The expression profile of microRNAs in mouse embryos";
RL Nucleic Acids Res. 34:1765-1771(2006).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [5]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676818; Mir133a-1.
DR ENTREZGENE; 387151; Mir133a-1.
XX
CC This mature miRNA sequence was named miR-133 in reference [1], and renamed
CC miR-133a on subsequent identification of a homologue differing at the
CC terminal 3' position (MIR:MI0000821). The mature sequence shown here
CC represents the most commonly cloned form from large-scale cloning studies
CC [3]. The 5' end of the miRNA may be offset with respect to previous
CC annotations.
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..27
FT /accession="MIMAT0003473"
FT /product="mmu-miR-133a-5p"
FT /evidence=experimental
FT /experiment="MPSS [2], Illumina [4-5]"
FT miRNA 43..64
FT /accession="MIMAT0000145"
FT /product="mmu-miR-133a-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Illumina [4-5]"
XX
SQ Sequence 68 BP; 19 A; 18 C; 14 G; 0 T; 17 other;
gcuaaagcug guaaaaugga accaaaucgc cucuucaaug gauuuggucc ccuucaacca 60
gcuguagc 68
//
ID mmu-mir-134 standard; RNA; MMU; 71 BP.
XX
AC MI0000160;
XX
DE Mus musculus miR-134 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 15310658.
RA Seitz H, Royo H, Bortolin ML, Lin SP, Ferguson-Smith AC, Cavaille J;
RT "A large imprinted microRNA gene cluster at the mouse Dlk1-Gtl2 domain";
RL Genome Res. 14:1741-1748(2004).
XX
RN [3]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [6]
RX PUBMED; 20668074.
RA Zhu JY, Strehle M, Frohn A, Kremmer E, Hofig KP, Meister G, Adler H;
RT "Identification and analysis of expression of novel microRNAs of murine
RT gammaherpesvirus 68";
RL J Virol. 84:10266-10275(2010).
XX
RN [7]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676819; Mir134.
DR ENTREZGENE; 387152; Mir134.
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..28
FT /accession="MIMAT0000146"
FT /product="mmu-miR-134-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3-4], PCR [2], Illumina [5,7]"
FT miRNA 46..65
FT /accession="MIMAT0016985"
FT /product="mmu-miR-134-3p"
FT /evidence=experimental
FT /experiment="454 [6], Illumina [7]"
XX
SQ Sequence 71 BP; 12 A; 21 C; 22 G; 0 T; 16 other;
agggugugug acugguugac cagaggggcg ugcacucugu ucacccugug ggccaccuag 60
ucaccaaccc u 71
//
ID mmu-mir-135a-1 standard; RNA; MMU; 90 BP.
XX
AC MI0000161;
XX
DE Mus musculus miR-135a-1 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 15634332.
RA Weber MJ;
RT "New human and mouse microRNA genes found by homology search";
RL FEBS J. 272:59-73(2005).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [5]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676820; Mirn135a-1.
DR ENTREZGENE; 387153; Mir135a-1.
XX
FH Key Location/Qualifiers
FH
FT miRNA 17..39
FT /accession="MIMAT0000147"
FT /product="mmu-miR-135a-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Illumina [4-5]"
FT miRNA 56..77
FT /accession="MIMAT0004531"
FT /product="mmu-miR-135a-1-3p"
FT /evidence=experimental
FT /experiment="cloned [3], Illumina [4-5]"
XX
SQ Sequence 90 BP; 16 A; 18 C; 24 G; 0 T; 32 other;
aggccucacu guucucuaug gcuuuuuauu ccuaugugau ucuauugcuc gcucauauag 60
ggauuggagc cguggcguac ggugaggaua 90
//
ID mmu-mir-136 standard; RNA; MMU; 62 BP.
XX
AC MI0000162;
XX
DE Mus musculus miR-136 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [3]
RX PUBMED; 15854907.
RA Davis E, Caiment F, Tordoir X, Cavaille J, Ferguson-Smith A, Cockett N,
RA Georges M, Charlier C;
RT "RNAi-mediated allelic trans-interaction at the imprinted Rtl1/Peg11
RT locus";
RL Curr Biol. 15:743-749(2005).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [6]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676821; Mir136.
DR ENTREZGENE; 387154; Mir136.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [4].
XX
FH Key Location/Qualifiers
FH
FT miRNA 5..26
FT /accession="MIMAT0000148"
FT /product="mmu-miR-136-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2,4], PCR [3], Illumina [5-6]"
FT miRNA 40..61
FT /accession="MIMAT0004532"
FT /product="mmu-miR-136-3p"
FT /evidence=experimental
FT /experiment="cloned [4], Illumina [5-6]"
XX
SQ Sequence 62 BP; 14 A; 13 C; 12 G; 0 T; 23 other;
gaggacucca uuuguuuuga ugauggauuc uuaagcucca ucaucgucuc aaaugagucu 60
uc 62
//
ID mmu-mir-137 standard; RNA; MMU; 73 BP.
XX
AC MI0000163;
XX
DE Mus musculus miR-137 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [5]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676822; Mir137.
DR ENTREZGENE; 387155; Mir137.
XX
FH Key Location/Qualifiers
FH
FT miRNA 9..31
FT /accession="MIMAT0016986"
FT /product="mmu-miR-137-5p"
FT /evidence=experimental
FT /experiment="Illumina [5]"
FT miRNA 45..67
FT /accession="MIMAT0000149"
FT /product="mmu-miR-137-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Illumina [4-5]"
XX
SQ Sequence 73 BP; 16 A; 10 C; 23 G; 0 T; 24 other;
cuucggugac ggguauucuu ggguggauaa uacggauuac guuguuauug cuuaagaaua 60
cgcguagucg agg 73
//
ID mmu-mir-138-2 standard; RNA; MMU; 71 BP.
XX
AC MI0000164;
XX
DE Mus musculus miR-138-2 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 15634332.
RA Weber MJ;
RT "New human and mouse microRNA genes found by homology search";
RL FEBS J. 272:59-73(2005).
XX
RN [3]
RX PUBMED; 14691248.
RA Kim J, Krichevsky A, Grad Y, Hayes GD, Kosik KS, Church GM, Ruvkun G;
RT "Identification of many microRNAs that copurify with polyribosomes in
RT mammalian neurons";
RL Proc Natl Acad Sci U S A. 101:360-365(2004).
XX
RN [4]
RX PUBMED; 16738409.
RA Obernosterer G, Leuschner PJ, Alenius M, Martinez J;
RT "Post-transcriptional regulation of microRNA expression";
RL RNA. 12:1161-1167(2006).
XX
RN [5]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [6]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [7]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 3618733; Mir138-2.
DR ENTREZGENE; 723956; Mir138-2.
XX
CC Mouse miR-138 was cloned from mouse brain tissue in [1]. There are 2
CC predicted hairpin precursor structures in the mouse genome, each has a
CC closely related human homologue [2]. mir-138-1 (MIR:MI0000722) is found
CC on mouse chromosome 8, and mir-138-2 (MIR:MI0000164, previously named
CC mir-138 here) on chromosome 9. Kim et al. and Obernosterer et al.
CC independently show that the mature product is a 23mer [3,4].
XX
FH Key Location/Qualifiers
FH
FT miRNA 2..24
FT /accession="MIMAT0000150"
FT /product="mmu-miR-138-5p"
FT /evidence=experimental
FT /experiment="cloned [1,5], Illumina [6-7]"
FT miRNA 49..69
FT /accession="MIMAT0016987"
FT /product="mmu-miR-138-2-3p"
FT /evidence=experimental
FT /experiment="Illumina [7]"
XX
SQ Sequence 71 BP; 14 A; 21 C; 20 G; 0 T; 16 other;
cagcuggugu ugugaaucag gccgacgagc agcgcauccu cuuacccggc uauuucacga 60
caccaggguu g 71
//
ID mmu-mir-140 standard; RNA; MMU; 70 BP.
XX
AC MI0000165;
XX
DE Mus musculus miR-140 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [3]
RX PUBMED; 16766679.
RA Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N,
RA Imai H;
RT "Identification and characterization of two novel classes of small RNAs in
RT the mouse germline: retrotransposon-derived siRNAs in oocytes and germline
RT small RNAs in testes";
RL Genes Dev. 20:1732-1743(2006).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [6]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676825; Mir140.
DR ENTREZGENE; 387158; Mir140.
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..27
FT /accession="MIMAT0000151"
FT /product="mmu-miR-140-5p"
FT /evidence=experimental
FT /experiment="cloned [1-4], Illumina [5-6]"
FT miRNA 45..65
FT /accession="MIMAT0000152"
FT /product="mmu-miR-140-3p"
FT /evidence=experimental
FT /experiment="cloned [2,4], Illumina [5-6]"
XX
SQ Sequence 70 BP; 15 A; 18 C; 19 G; 0 T; 18 other;
ccugccagug guuuuacccu augguagguu acgucaugcu guucuaccac aggguagaac 60
cacggacagg 70
//
ID mmu-mir-141 standard; RNA; MMU; 72 BP.
XX
AC MI0000166;
XX
DE Mus musculus miR-141 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [3]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [6]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676826; Mir141.
DR ENTREZGENE; 387159; Mir141.
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..27
FT /accession="MIMAT0004533"
FT /product="mmu-miR-141-5p"
FT /evidence=experimental
FT /experiment="cloned [4], Illumina [5-6]"
FT miRNA 48..69
FT /accession="MIMAT0000153"
FT /product="mmu-miR-141-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3-4], Illumina [5-6]"
XX
SQ Sequence 72 BP; 16 A; 15 C; 21 G; 0 T; 20 other;
ggguccaucu uccagugcag uguuggaugg uugaaguaug aagcuccuaa cacugucugg 60
uaaagauggc cc 72
//
ID mmu-mir-142a standard; RNA; MMU; 64 BP.
XX
AC MI0000167;
XX
DE Mus musculus miR-142 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [5]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676827; Mir142.
DR ENTREZGENE; 387160; Mir142.
XX
CC Expression of miRNAs from both 5' and 3' arms of this precursor have been
CC independently verified in the mouse gut tissue [1] and in embryonic stem
CC cells [2]. The mature sequence shown here represents the most commonly
CC cloned form from large-scale cloning studies [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 4..24
FT /accession="MIMAT0000154"
FT /product="mmu-miR-142a-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Illumina [4-5]"
FT miRNA 40..62
FT /accession="MIMAT0000155"
FT /product="mmu-miR-142a-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Illumina [4-5]"
XX
SQ Sequence 64 BP; 20 A; 12 C; 15 G; 0 T; 17 other;
acccauaaag uagaaagcac uacuaacagc acuggagggu guaguguuuc cuacuuuaug 60
gaug 64
//
ID mmu-mir-144 standard; RNA; MMU; 66 BP.
XX
AC MI0000168;
XX
DE Mus musculus miR-144 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676829; Mir144.
DR ENTREZGENE; 387162; Mir144.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..28
FT /accession="MIMAT0016988"
FT /product="mmu-miR-144-5p"
FT /evidence=experimental
FT /experiment="Illumina [4]"
FT miRNA 43..62
FT /accession="MIMAT0000156"
FT /product="mmu-miR-144-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Illumina [3-4]"
XX
SQ Sequence 66 BP; 20 A; 9 C; 16 G; 0 T; 21 other;
ggcugggaua ucaucauaua cuguaaguuu gugaugagac acuacaguau agaugaugua 60
cuaguc 66
//
ID mmu-mir-145a standard; RNA; MMU; 70 BP.
XX
AC MI0000169;
XX
DE Mus musculus miR-145 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676830; Mir145.
DR ENTREZGENE; 387163; Mir145.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..29
FT /accession="MIMAT0000157"
FT /product="mmu-miR-145a-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Illumina [3-4]"
FT miRNA 47..68
FT /accession="MIMAT0004534"
FT /product="mmu-miR-145a-3p"
FT /evidence=experimental
FT /experiment="cloned [2], Illumina [3-4]"
XX
SQ Sequence 70 BP; 15 A; 16 C; 18 G; 0 T; 21 other;
cucacggucc aguuuuccca ggaaucccuu ggaugcuaag auggggauuc cuggaaauac 60
uguucuugag 70
//
ID mmu-mir-146a standard; RNA; MMU; 65 BP.
XX
AC MI0000170;
XX
DE Mus musculus miR-146a stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676831; Mirn146.
DR ENTREZGENE; 387164; Mir146.
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..27
FT /accession="MIMAT0000158"
FT /product="mmu-miR-146a-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Illumina [3-4]"
FT miRNA 42..63
FT /accession="MIMAT0016989"
FT /product="mmu-miR-146a-3p"
FT /evidence=experimental
FT /experiment="Illumina [4]"
XX
SQ Sequence 65 BP; 18 A; 13 C; 13 G; 0 T; 21 other;
agcucugaga acugaauucc auggguuaua ucaaugucag accugugaaa uucaguucuu 60
cagcu 65
//
ID mmu-mir-149 standard; RNA; MMU; 66 BP.
XX
AC MI0000171;
XX
DE Mus musculus miR-149 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676834; Mir149.
DR ENTREZGENE; 387167; Mir149.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 4..26
FT /accession="MIMAT0000159"
FT /product="mmu-miR-149-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Illumina [3-4]"
FT miRNA 44..65
FT /accession="MIMAT0016990"
FT /product="mmu-miR-149-3p"
FT /evidence=experimental
FT /experiment="Illumina [4]"
XX
SQ Sequence 66 BP; 6 A; 16 C; 29 G; 0 T; 15 other;
ggcucuggcu ccgugucuuc acucccgugu uuguccgagg agggagggag ggacgggggc 60
ggugcu 66
//
ID mmu-mir-150 standard; RNA; MMU; 65 BP.
XX
AC MI0000172;
XX
DE Mus musculus miR-150 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676835; Mir150.
DR ENTREZGENE; 387168; Mir150.
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..27
FT /accession="MIMAT0000160"
FT /product="mmu-miR-150-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Illumina [3-4]"
FT miRNA 42..63
FT /accession="MIMAT0004535"
FT /product="mmu-miR-150-3p"
FT /evidence=experimental
FT /experiment="cloned [2], Illumina [3-4]"
XX
SQ Sequence 65 BP; 10 A; 22 C; 19 G; 0 T; 14 other;
cccugucucc caacccuugu accagugcug ugccucagac ccugguacag gccuggggga 60
uaggg 65
//
ID mmu-mir-151 standard; RNA; MMU; 68 BP.
XX
AC MI0000173;
XX
DE Mus musculus miR-151 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676836; Mir151.
DR ENTREZGENE; 387169; Mir151.
XX
FH Key Location/Qualifiers
FH
FT miRNA 8..28
FT /accession="MIMAT0004536"
FT /product="mmu-miR-151-5p"
FT /evidence=experimental
FT /experiment="cloned [2], Illumina [3-4]"
FT miRNA 43..63
FT /accession="MIMAT0000161"
FT /product="mmu-miR-151-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Illumina [3-4]"
XX
SQ Sequence 68 BP; 13 A; 22 C; 17 G; 0 T; 16 other;
ccugcccucg aggagcucac agucuaguau gucuccuccc uacuagacug aggcuccuug 60
aggacagg 68
//
ID mmu-mir-152 standard; RNA; MMU; 73 BP.
XX
AC MI0000174;
XX
DE Mus musculus miR-152 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [3]
RX PUBMED; 16766679.
RA Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N,
RA Imai H;
RT "Identification and characterization of two novel classes of small RNAs in
RT the mouse germline: retrotransposon-derived siRNAs in oocytes and germline
RT small RNAs in testes";
RL Genes Dev. 20:1732-1743(2006).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [6]
RX PUBMED; 20668074.
RA Zhu JY, Strehle M, Frohn A, Kremmer E, Hofig KP, Meister G, Adler H;
RT "Identification and analysis of expression of novel microRNAs of murine
RT gammaherpesvirus 68";
RL J Virol. 84:10266-10275(2010).
XX
RN [7]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676837; Mir152.
DR ENTREZGENE; 387170; Mir152.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [4].
XX
FH Key Location/Qualifiers
FH
FT miRNA 8..31
FT /accession="MIMAT0016991"
FT /product="mmu-miR-152-5p"
FT /evidence=experimental
FT /experiment="454 [6], Illumina [7]"
FT miRNA 47..67
FT /accession="MIMAT0000162"
FT /product="mmu-miR-152-3p"
FT /evidence=experimental
FT /experiment="cloned [1-4], Illumina [5,7]"
XX
SQ Sequence 73 BP; 13 A; 21 C; 24 G; 0 T; 15 other;
ccgggccuag guucugugau acacuccgac ucgggcucug gagcagucag ugcaugacag 60
aacuugggcc cgg 73
//
ID mmu-mir-153 standard; RNA; MMU; 69 BP.
XX
AC MI0000175;
XX
DE Mus musculus miR-153 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [5]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676838; Mir153.
DR ENTREZGENE; 387171; Mir153.
XX
FH Key Location/Qualifiers
FH
FT miRNA 5..27
FT /accession="MIMAT0016992"
FT /product="mmu-miR-153-5p"
FT /evidence=experimental
FT /experiment="Illumina [5]"
FT miRNA 44..65
FT /accession="MIMAT0000163"
FT /product="mmu-miR-153-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Illumina [4-5]"
XX
SQ Sequence 69 BP; 18 A; 12 C; 17 G; 0 T; 22 other;
cggugucauu uuugugacgu ugcagcuagu aauaugagcc caguugcaua gucacaaaag 60
ugaucauug 69
//
ID mmu-mir-154 standard; RNA; MMU; 66 BP.
XX
AC MI0000176;
XX
DE Mus musculus miR-154 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 15310658.
RA Seitz H, Royo H, Bortolin ML, Lin SP, Ferguson-Smith AC, Cavaille J;
RT "A large imprinted microRNA gene cluster at the mouse Dlk1-Gtl2 domain";
RL Genome Res. 14:1741-1748(2004).
XX
RN [3]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [6]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676839; Mir154.
DR ENTREZGENE; 387172; Mir154.
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..27
FT /accession="MIMAT0000164"
FT /product="mmu-miR-154-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3-4], PCR [2], Illumina [5-6]"
FT miRNA 42..63
FT /accession="MIMAT0004537"
FT /product="mmu-miR-154-3p"
FT /evidence=experimental
FT /experiment="cloned [4], Illumina [5-6]"
XX
SQ Sequence 66 BP; 14 A; 13 C; 14 G; 0 T; 25 other;
gaagauaggu uauccguguu gccuucgcuu uauucgugac gaaucauaca cgguugaccu 60
auuuuu 66
//
ID mmu-mir-155 standard; RNA; MMU; 65 BP.
XX
AC MI0000177;
XX
DE Mus musculus miR-155 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 15634332.
RA Weber MJ;
RT "New human and mouse microRNA genes found by homology search";
RL FEBS J. 272:59-73(2005).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 20668074.
RA Zhu JY, Strehle M, Frohn A, Kremmer E, Hofig KP, Meister G, Adler H;
RT "Identification and analysis of expression of novel microRNAs of murine
RT gammaherpesvirus 68";
RL J Virol. 84:10266-10275(2010).
XX
RN [5]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676840; Mir155.
DR ENTREZGENE; 387173; Mir155.
XX
CC Mouse mir-155 resides in the non-coding BIC transcript (EMBL:AY096003),
CC located on chromosome 16 [2]. The mature sequence shown here represents
CC the most commonly cloned form from large-scale cloning studies [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 4..26
FT /accession="MIMAT0000165"
FT /product="mmu-miR-155-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Illumina [5]"
FT miRNA 43..63
FT /accession="MIMAT0016993"
FT /product="mmu-miR-155-3p"
FT /evidence=experimental
FT /experiment="454 [4], Illumina [5]"
XX
SQ Sequence 65 BP; 14 A; 13 C; 15 G; 0 T; 23 other;
cuguuaaugc uaauugugau agggguuuug gccucugacu gacuccuacc uguuagcauu 60
aacag 65
//
ID ath-MIR156a standard; RNA; ATH; 123 BP.
XX
AC MI0000178;
XX
DE Arabidopsis thaliana miR156a stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR RFAM; RF00073; mir-156.
DR ASRP; ASRP1423; miR156.
XX
CC MIR156a is thought to target 10 mRNAs coding for proteins containing the
CC Squamosa-promoter Binding Protein (SBP) box [1]. The complementary sites
CC are downstream of this conserved domain, within a poorly conserved
CC protein-coding context or the 3' UTR [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 21..40
FT /accession="MIMAT0000166"
FT /product="ath-miR156a-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 5'RACE [3], 454
FT [4-5], MPSS [4], Illumina [6]"
FT miRNA 83..104
FT /accession="MIMAT0031865"
FT /product="ath-miR156a-3p"
FT /evidence=not_experimental
XX
SQ Sequence 123 BP; 34 A; 29 C; 26 G; 0 T; 34 other;
caagagaaac gcaaagaaac ugacagaaga gagugagcac acaaaggcaa uuugcauauc 60
auugcacuug cuucucuugc gugcucacug cucuuucugu cagauuccgg ugcugaucuc 120
uuu 123
//
ID ath-MIR156b standard; RNA; ATH; 183 BP.
XX
AC MI0000179;
XX
DE Arabidopsis thaliana miR156b stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR RFAM; RF00073; mir-156.
DR ASRP; ASRP1423; miR156.
XX
CC MIR156b is thought to target 10 mRNAs coding for proteins containing the
CC Squamosa-promoter Binding Protein (SBP) box [1]. The complementary sites
CC are downstream of this conserved domain, within a poorly conserved
CC protein-coding context or the 3' UTR [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 47..66
FT /accession="MIMAT0000167"
FT /product="ath-miR156b-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 454 [4-5], MPSS
FT [4], Illumina [6]"
FT miRNA 106..128
FT /accession="MIMAT0031866"
FT /product="ath-miR156b-3p"
FT /evidence=not_experimental
XX
SQ Sequence 183 BP; 41 A; 43 C; 44 G; 0 T; 55 other;
gcuagaagag ggagagaugg ugauugagga augcaacaga gaaaacugac agaagagagu 60
gagcacaugc aggcacuguu augugucuau aacuuugcgu gugcgugcuc accucucuuu 120
cugucaguug ccuaucucug ccugcuugac cucucucucu cucucucucu cucaaauuug 180
gcu 183
//
ID ath-MIR156c standard; RNA; ATH; 104 BP.
XX
AC MI0000180;
XX
DE Arabidopsis thaliana miR156c stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR RFAM; RF00073; mir-156.
DR ASRP; ASRP1423; miR156.
XX
CC MIR156c is thought to target 10 mRNAs coding for proteins containing the
CC Squamosa-promoter Binding Protein (SBP) box [1]. The complementary sites
CC are downstream of this conserved domain, within a poorly conserved
CC protein-coding context or the 3' UTR [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 12..31
FT /accession="MIMAT0000168"
FT /product="ath-miR156c-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 5'RACE [3], 454
FT [4-5], MPSS [4], Illumina [6]"
FT miRNA 75..96
FT /accession="MIMAT0031867"
FT /product="ath-miR156c-3p"
FT /evidence=not_experimental
XX
SQ Sequence 104 BP; 25 A; 26 C; 24 G; 0 T; 29 other;
cgcauagaaa cugacagaag agagugagca cacaaaggca cuuugcaugu ucgaugcauu 60
ugcuucucuu gcgugcucac ugcucuaucu gucagauucc ggcu 104
//
ID ath-MIR156d standard; RNA; ATH; 118 BP.
XX
AC MI0000181;
XX
DE Arabidopsis thaliana miR156d stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR RFAM; RF00073; mir-156.
DR ASRP; ASRP1423; miR156.
XX
CC MIR156d is thought to target 10 mRNAs coding for proteins containing the
CC Squamosa-promoter Binding Protein (SBP) box [1]. The complementary sites
CC are downstream of this conserved domain, within a poorly conserved
CC protein-coding context or the 3' UTR [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 18..37
FT /accession="MIMAT0000169"
FT /product="ath-miR156d-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 454 [4-5], MPSS
FT [4], Illumina [6]"
FT miRNA 85..107
FT /accession="MIMAT0031868"
FT /product="ath-miR156d-3p"
FT /evidence=not_experimental
XX
SQ Sequence 118 BP; 33 A; 17 C; 30 G; 0 T; 38 other;
gaugggggaa aagaaguuga cagaagagag ugagcacaca aaggggaagu uguauaaaag 60
uuuuguauau gguugcuuuu gcgugcucac ucucuuuuug ucauaacuuc uccuucau 118
//
ID ath-MIR156e standard; RNA; ATH; 107 BP.
XX
AC MI0000182;
XX
DE Arabidopsis thaliana miR156e stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR RFAM; RF00073; mir-156.
DR ASRP; ASRP1423; miR156.
XX
CC MIR156e is thought to target 10 mRNAs coding for proteins containing the
CC Squamosa-promoter Binding Protein (SBP) box [1]. The complementary sites
CC are downstream of this conserved domain, within a poorly conserved
CC protein-coding context or the 3' UTR [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..26
FT /accession="MIMAT0000170"
FT /product="ath-miR156e"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 5'RACE [3], 454
FT [4-5], MPSS [4], Illumina [6]"
XX
SQ Sequence 107 BP; 21 A; 21 C; 28 G; 0 T; 37 other;
aggaggugac agaagagagu gagcacacau ggugguuucu ugcaugcuuu uuugauuagg 60
guuucaugcu ugaagcuaug ugugcuuacu cucucucugu caccccu 107
//
ID ath-MIR156f standard; RNA; ATH; 132 BP.
XX
AC MI0000183;
XX
DE Arabidopsis thaliana miR156f stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR RFAM; RF00073; mir-156.
DR ASRP; ASRP1423; miR156.
XX
CC MIR156f is thought to target 10 mRNAs coding for proteins containing the
CC Squamosa-promoter Binding Protein (SBP) box [1]. The complementary sites
CC are downstream of this conserved domain, within a poorly conserved
CC protein-coding context or the 3' UTR [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 21..40
FT /accession="MIMAT0000171"
FT /product="ath-miR156f-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 5'RACE [3], 454
FT [4-5], MPSS [4], Illumina [6]"
FT miRNA 92..112
FT /accession="MIMAT0031869"
FT /product="ath-miR156f-3p"
FT /evidence=not_experimental
XX
SQ Sequence 132 BP; 26 A; 34 C; 32 G; 0 T; 40 other;
gaguggugag gaauugaugg ugacagaaga gagugagcac acaugguggc uuucuugcau 60
auuugaaggu uccaugcuug aagcuaugug ugcucacucu cuauccguca cccccuucuc 120
ucccucuccc uc 132
//
ID ath-MIR157a standard; RNA; ATH; 98 BP.
XX
AC MI0000184;
XX
DE Arabidopsis thaliana miR157a stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR ASRP; ASRP1424; miR157.
XX
CC MIR157a is thought, like the miR156 family, to target mRNAs coding for
CC proteins containing the Squamosa-promoter Binding Protein (SBP) box [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 4..24
FT /accession="MIMAT0000172"
FT /product="ath-miR157a-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 3'RACE [3], 454
FT [4-5], MPSS [4], Illumina [6]"
FT miRNA 75..95
FT /accession="MIMAT0031870"
FT /product="ath-miR157a-3p"
FT /evidence=not_experimental
XX
SQ Sequence 98 BP; 24 A; 22 C; 21 G; 0 T; 31 other;
guguugacag aagauagaga gcacagauga ugagauacaa uucggagcau guucuuugca 60
ucuuacuccu uugugcucuc uagccuucug ucaucacc 98
//
ID ath-MIR157b standard; RNA; ATH; 132 BP.
XX
AC MI0000185;
XX
DE Arabidopsis thaliana miR157b stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR ASRP; ASRP1424; miR157.
XX
CC MIR157b is thought, like the miR156 family, to target mRNAs coding for
CC proteins containing the Squamosa-promoter Binding Protein (SBP) box [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 19..39
FT /accession="MIMAT0000173"
FT /product="ath-miR157b-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 3'RACE [3], 454
FT [4-5], MPSS [4], Illumina [6]"
FT miRNA 90..110
FT /accession="MIMAT0031871"
FT /product="ath-miR157b-3p"
FT /evidence=not_experimental
XX
SQ Sequence 132 BP; 32 A; 33 C; 26 G; 0 T; 41 other;
ugggaggcau ugauaguguu gacagaagau agagagcaca gaugauaaga uacaauuccu 60
cgcagcuucu uugcaucuua cuccuuugug cucucuagcc uucugucauc acccguuauu 120
ugccaucacc ca 132
//
ID ath-MIR157c standard; RNA; ATH; 217 BP.
XX
AC MI0000186;
XX
DE Arabidopsis thaliana miR157c stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR ASRP; ASRP1424; miR157.
XX
CC MIR157c is thought, like the miR156 family, to target mRNAs coding for
CC proteins containing the Squamosa-promoter Binding Protein (SBP) box [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 24..44
FT /accession="MIMAT0000174"
FT /product="ath-miR157c-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 5'RACE [3], 454
FT [4-5], MPSS [4], Illumina [6]"
FT miRNA 170..190
FT /accession="MIMAT0031872"
FT /product="ath-miR157c-3p"
FT /evidence=not_experimental
XX
SQ Sequence 217 BP; 71 A; 40 C; 43 G; 0 T; 63 other;
agguuugaga gugauguugg uuguugacag aagauagaga gcacuaagga ugacaugcaa 60
guacauacau auauaucauc acaccgcaug uggaugauaa aauauguaua acaaauucaa 120
agaaagagag ggagagaaag agagagaacc ugcaucucua cucuuuugug cucucuauac 180
uucugucacc accuuuaucu cuucuucucu cuaaccu 217
//
ID ath-MIR157d standard; RNA; ATH; 221 BP.
XX
AC MI0000187;
XX
DE Arabidopsis thaliana miR157d stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
CC MIR157d is thought, like the MIR156 family, to target mRNAs coding for
CC proteins containing the Squamosa-promoter Binding Protein (SBP) box [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 24..43
FT /accession="MIMAT0000175"
FT /product="ath-miR157d"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 5'RACE [3], 454
FT [4-5], MPSS [4], Illumina [6]"
XX
SQ Sequence 221 BP; 69 A; 39 C; 42 G; 0 T; 71 other;
guggagggug auaguguggu ugcugacaga agauagagag cacuaaggau gcuaugcaaa 60
acagacacag auauguguuu cuaauuguau uucauacuuu aaccucaaag uugauauaaa 120
aaaagaaaga aagauagaag agcuagaaga cuaucugcau cucuauuccu augugcucuc 180
uaugcuucug ucaucaccuu ucuuucucua uuucucucua c 221
//
ID ath-MIR158a standard; RNA; ATH; 100 BP.
XX
AC MI0000188;
XX
DE Arabidopsis thaliana miR158a stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR ASRP; ASRP142; miR158.
XX
FH Key Location/Qualifiers
FH
FT miRNA 20..40
FT /accession="MIMAT0031873"
FT /product="ath-miR158a-5p"
FT /evidence=not_experimental
FT miRNA 63..82
FT /accession="MIMAT0000176"
FT /product="ath-miR158a-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 454 [4-5], MPSS
FT [4], Illumina [6]"
XX
SQ Sequence 100 BP; 27 A; 22 C; 19 G; 0 T; 32 other;
acacgucauc ucugugcuuc uuugucuaca auuuuggaaa aagugaugac gccauugcuc 60
uuucccaaau guagacaaag caauaccgug augaugucgu 100
//
ID ath-MIR159a standard; RNA; ATH; 184 BP.
XX
AC MI0000189;
XX
DE Arabidopsis thaliana miR159a stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12226481.
RA Mette MF, van der Winden J, Matzke M, Matzke AJ;
RT "Short RNAs can identify new candidate transposable element families in
RT Arabidopsis";
RL Plant Physiol. 130:6-9(2002).
XX
RN [3]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [4]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [5]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [6]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [7]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR ASRP; ASRP1425; miR159.
XX
CC MIR159a was identified independently by Reinhart et al. [1] and Mette et
CC al. [2]. The latter group referred to this sequence by the internal
CC identifier MIR40a. This sequence is not related to C. elegans miR-40.
CC MIR159a is thought to target mRNAs coding for MYB proteins which are known
CC to bind to the promoter of the floral meristem identity gene LEAFY [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 163..183
FT /accession="MIMAT0000177"
FT /product="ath-miR159a"
FT /evidence=experimental
FT /experiment="cloned [1,4], Northern [1], 5'RACE [4], 454
FT [5-6], MPSS [5], Illumina [7]"
XX
SQ Sequence 184 BP; 55 A; 32 C; 40 G; 0 T; 57 other;
guagagcucc uuaaaguuca aacaugaguu gagcagggua aagaaaagcu gcuaagcuau 60
ggaucccaua agcccuaauc cuuguaaagu aaaaaaggau uugguuauau ggauugcaua 120
ucucaggagc uuuaacuugc ccuuuaaugg cuuuuacucu ucuuuggauu gaagggagcu 180
cuac 184
//
ID ath-MIR160a standard; RNA; ATH; 85 BP.
XX
AC MI0000190;
XX
DE Arabidopsis thaliana miR160a stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
RN [7]
RX PUBMED; 24119003.
RA Vidal EA, Moyano TC, Krouk G, Katari MS, Tanurdzic M, McCombie WR, Coruzzi
RA GM, Gutierrez RA;
RT "Integrated RNA-seq and sRNA-seq analysis identifies novel
RT nitrate-responsive genes in Arabidopsis thaliana roots";
RL BMC Genomics. 14:701(2013).
XX
DR ASRP; ASRP1426; miR160.
XX
CC MIR160a is thought to target mRNAs coding for auxin response factor
CC proteins [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 4..24
FT /accession="MIMAT0000178"
FT /product="ath-miR160a-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 5'RACE [3], 454
FT [4-5], MPSS [4], Illumina [6]"
FT miRNA 64..84
FT /accession="MIMAT0031874"
FT /product="ath-miR160a-3p"
FT /evidence=experimental
FT /experiment="Illumina [7]"
XX
SQ Sequence 85 BP; 17 A; 22 C; 24 G; 0 T; 22 other;
guaugccugg cucccuguau gccauaugcu gagcccaucg aguaucgaug accuccgugg 60
auggcguaug aggagccaug cauau 85
//
ID ath-MIR160b standard; RNA; ATH; 89 BP.
XX
AC MI0000191;
XX
DE Arabidopsis thaliana miR160b stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR ASRP; ASRP1426; miR160.
XX
CC MIR160b is thought to target mRNAs coding for auxin response factor
CC proteins [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 5..25
FT /accession="MIMAT0000179"
FT /product="ath-miR160b"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 5'RACE [3], 454
FT [4-5], MPSS [4], Illumina [6]"
XX
SQ Sequence 89 BP; 26 A; 21 C; 20 G; 0 T; 22 other;
gucgugccug gcucccugua ugccacaaga aaacaucgau uuaguuucaa aaucgaucac 60
uaguggcgua cagaguaguc aagcaugac 89
//
ID ath-MIR160c standard; RNA; ATH; 89 BP.
XX
AC MI0000192;
XX
DE Arabidopsis thaliana miR160c stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
RN [7]
RX PUBMED; 24119003.
RA Vidal EA, Moyano TC, Krouk G, Katari MS, Tanurdzic M, McCombie WR, Coruzzi
RA GM, Gutierrez RA;
RT "Integrated RNA-seq and sRNA-seq analysis identifies novel
RT nitrate-responsive genes in Arabidopsis thaliana roots";
RL BMC Genomics. 14:701(2013).
XX
DR ASRP; ASRP1426; miR160.
XX
CC MIR160c is thought to target mRNAs coding for auxin response factor
CC proteins [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 5..25
FT /accession="MIMAT0000180"
FT /product="ath-miR160c-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 5'RACE [3], 454
FT [4-5], MPSS [4], Illumina [6]"
FT miRNA 68..88
FT /accession="MIMAT0031875"
FT /product="ath-miR160c-3p"
FT /evidence=experimental
FT /experiment="Illumina [7]"
XX
SQ Sequence 89 BP; 19 A; 20 C; 26 G; 0 T; 24 other;
guuaugccug gcucccugua ugccacgagu ggauaccgau uuugguuuua aaaucggcug 60
ccgguggcgu acaaggaguc aagcaugac 89
//
ID ath-MIR161 standard; RNA; ATH; 173 BP.
XX
AC MI0000193;
XX
DE Arabidopsis thaliana miR161 stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [5]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [6]
RX PUBMED; 18542052.
RA German MA, Pillay M, Jeong DH, Hetawal A, Luo S, Janardhanan P, Kannan V,
RA Rymarquis LA, Nobuta K, German R, De Paoli E, Lu C, Schroth G, Meyers BC,
RA Green PJ;
RT "Global identification of microRNA-target RNA pairs by parallel analysis
RT of RNA ends";
RL Nat Biotechnol. 26:941-946(2008).
XX
RN [7]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR ASRP; ASRP111; miR161.
XX
CC MIR161 is to target mRNAs coding for PPR repeat proteins [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 38..58
FT /accession="MIMAT0006779"
FT /product="ath-miR161.2"
FT /evidence=experimental
FT /experiment="cloned [3], PARE [6], Illumina [7]"
FT miRNA 47..67
FT /accession="MIMAT0000181"
FT /product="ath-miR161.1"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 5'RACE [3], 454
FT [4-5], MPSS [5], Illumina [7]"
XX
SQ Sequence 173 BP; 48 A; 30 C; 36 G; 0 T; 59 other;
ugcuugaucu cgguuuuuga ccaguuuauu gcgucgauca augcauugaa agugacuaca 60
ucgggguucc gauuuuuuuu guucuucaua ugaugaagcg gaaacaguaa ucaacccugg 120
uuuagucacu uucacugcau uaaucaaugc auuuguaaaa agagggaaaa gca 173
//
ID ath-MIR162a standard; RNA; ATH; 140 BP.
XX
AC MI0000194;
XX
DE Arabidopsis thaliana miR162a stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
DR ASRP; ASRP395; miR162.
XX
FH Key Location/Qualifiers
FH
FT miRNA 26..47
FT /accession="MIMAT0031876"
FT /product="ath-miR162a-5p"
FT /evidence=not_experimental
FT miRNA 89..109
FT /accession="MIMAT0000182"
FT /product="ath-miR162a-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 3'RACE [3],
FT 5'RACE [3], 454 [4-5], MPSS [4]"
XX
SQ Sequence 140 BP; 39 A; 27 C; 31 G; 0 T; 43 other;
uaguuggaag aagagugaga gucgcuggag gcagcgguuc aucgaucucu uccugugaac 60
acauuaaaaa uguaaaagca ugaauagauc gauaaaccuc ugcauccagc guuugccucu 120
uguaucuuuc uuauugacuu 140
//
ID ath-MIR162b standard; RNA; ATH; 111 BP.
XX
AC MI0000195;
XX
DE Arabidopsis thaliana miR162b stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
DR ASRP; ASRP395; miR162.
XX
FH Key Location/Qualifiers
FH
FT miRNA 13..34
FT /accession="MIMAT0031877"
FT /product="ath-miR162b-5p"
FT /evidence=not_experimental
FT miRNA 79..99
FT /accession="MIMAT0000183"
FT /product="ath-miR162b-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 3'RACE [3],
FT 5'RACE [3], 454 [4-5], MPSS [4]"
XX
SQ Sequence 111 BP; 29 A; 24 C; 25 G; 0 T; 33 other;
gagugaaguc gcuggaggca gcgguucauc gaucaauucc ugugaauauu uauuuuuguu 60
uacaaaagca agaaucgauc gauaaaccuc ugcauccagc gcugcuugcu c 111
//
ID ath-MIR163 standard; RNA; ATH; 331 BP.
XX
AC MI0000196;
XX
DE Arabidopsis thaliana miR163 stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [3]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [4]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [5]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR ASRP; ASRP1390; miR163.
XX
FH Key Location/Qualifiers
FH
FT miRNA 294..317
FT /accession="MIMAT0000184"
FT /product="ath-miR163"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1], 5'RACE [2], 454
FT [3-4], MPSS [3], Illumina [5]"
XX
SQ Sequence 331 BP; 93 A; 73 C; 77 G; 0 T; 88 other;
acccggugga uaaaaucgag uuccaaccuc uucaacgaca acgauuucaa cacucucuuc 60
caggaacaac uuccuccagg cagaugauac uaaagugcug gaguucccgg uuccugagag 120
ugaguccaua ucaaaaugcg cauucguuau cacuugguug aacccauuug gggauuuaaa 180
uuuggaggug aaauggaacg cguaauugau gacuccuacg uggaaccucu ucuuaggaag 240
agcacggucg aagaaguaac ugcgcagugc uuaaaucgua gaugcuaaag ucguugaaga 300
ggacuuggaa cuucgauauu aucccccgug u 331
//
ID ath-MIR164a standard; RNA; ATH; 113 BP.
XX
AC MI0000197;
XX
DE Arabidopsis thaliana miR164a stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR ASRP; ASRP1427; miR164.
XX
CC MIR164a is thought to target mRNAs coding for NAC domain containing
CC proteins such as Cup-Shaped Cotyledon 2 (CUC2) which is required for shoot
CC apical meristem formation [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 19..39
FT /accession="MIMAT0000185"
FT /product="ath-miR164a"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 5'RACE [3], 454
FT [4-5], MPSS [4], Illumina [6]"
XX
SQ Sequence 113 BP; 32 A; 31 C; 22 G; 0 T; 28 other;
gggugagaau cuccauguug gagaagcagg gcacgugcaa accaacaaac acgaaauccg 60
ucucauuugc uuauuugcac guacuuaacu ucuccaacau gagcucuuca ccc 113
//
ID ath-MIR164b standard; RNA; ATH; 153 BP.
XX
AC MI0000198;
XX
DE Arabidopsis thaliana miR164b stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR ASRP; ASRP1427; miR164.
XX
CC MIR164b is thought to target mRNAs coding for NAC domain containing
CC proteins such as Cup-Shaped Cotyledon 2 (CUC2) which is required for shoot
CC apical meristem formation [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 3..23
FT /accession="MIMAT0000186"
FT /product="ath-miR164b-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 5'RACE [3], 454
FT [4-5], MPSS [4], Illumina [6]"
FT miRNA 133..153
FT /accession="MIMAT0031878"
FT /product="ath-miR164b-3p"
FT /evidence=not_experimental
XX
SQ Sequence 153 BP; 39 A; 26 C; 38 G; 0 T; 50 other;
gauggagaag cagggcacgu gcauuacuag cucauauaua cacucucacc acaaaugcgu 60
guauauaugc ggaauuuugu gauauagaug ugugugugug uugaguguga ugauauggau 120
gaguuaguuc uucaugugcc caucuucacc auc 153
//
ID ath-MIR165a standard; RNA; ATH; 111 BP.
XX
AC MI0000199;
XX
DE Arabidopsis thaliana miR165a stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR RFAM; RF00075; mir-166.
DR ASRP; ASRP1428; miR165.
XX
CC MIR165a is thought to target mRNAs coding for HD-Zip transcription factors
CC including Phabulosa (PHB) and Phavoluta (PHV) that regulate axillary
CC meristem initiation and leaf development [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 8..28
FT /accession="MIMAT0031879"
FT /product="ath-miR165a-5p"
FT /evidence=not_experimental
FT miRNA 86..106
FT /accession="MIMAT0000187"
FT /product="ath-miR165a-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 5'RACE [3], 454
FT [4-5], MPSS [4], Illumina [6]"
XX
SQ Sequence 111 BP; 31 A; 20 C; 27 G; 0 T; 33 other;
guugagggga auguugucug gaucgaggau auuauagaua uauacaugug uauguuaaug 60
auucaaguga ucauagagag uauccucgga ccaggcuuca ucccccccaa c 111
//
ID ath-MIR165b standard; RNA; ATH; 182 BP.
XX
AC MI0000200;
XX
DE Arabidopsis thaliana miR165b stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR RFAM; RF00075; mir-166.
DR ASRP; ASRP1428; miR165.
XX
CC MIR165b is thought to target mRNAs coding for HD-Zip transcription factors
CC including Phabulosa (PHB) and Phavoluta (PHV) that regulate axillary
CC meristem initiation and leaf development [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 137..157
FT /accession="MIMAT0000188"
FT /product="ath-miR165b"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 454 [4-5], MPSS
FT [4], Illumina [6]"
XX
SQ Sequence 182 BP; 52 A; 33 C; 36 G; 0 T; 61 other;
ugaagaggcu auuucuguug uggggaaugu uguuuggauc gaggauauca uaaacgcaua 60
cacauguuua uauguuauga ugcauuauau gacugaugua auguacauau auauacauac 120
augccacaug guaucgucgg accaggcuuc aucccccuca acauguuaau ugccuucaau 180
ca 182
//
ID ath-MIR166a standard; RNA; ATH; 170 BP.
XX
AC MI0000201;
XX
DE Arabidopsis thaliana miR166a stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
RN [7]
RX PUBMED; 24119003.
RA Vidal EA, Moyano TC, Krouk G, Katari MS, Tanurdzic M, McCombie WR, Coruzzi
RA GM, Gutierrez RA;
RT "Integrated RNA-seq and sRNA-seq analysis identifies novel
RT nitrate-responsive genes in Arabidopsis thaliana roots";
RL BMC Genomics. 14:701(2013).
XX
DR RFAM; RF00075; mir-166.
DR ASRP; ASRP934; miR166.
XX
CC MIR166a, like miR165, is thought to target mRNAs coding for HD-Zip
CC transcription factors including Phabulosa (PHB) and Phavoluta (PHV) that
CC regulate axillary meristem initiation and leaf development [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 21..41
FT /accession="MIMAT0031880"
FT /product="ath-miR166a-5p"
FT /evidence=experimental
FT /experiment="Illumina [7]"
FT miRNA 134..154
FT /accession="MIMAT0000189"
FT /product="ath-miR166a-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 5'RACE [3], 454
FT [4-5], MPSS [4], Illumina [6]"
XX
SQ Sequence 170 BP; 29 A; 41 C; 39 G; 0 T; 61 other;
aggggcuuuc ucuuuugagg ggacuguugu cuggcucgag gacucuggcu cgcucuauuc 60
auguuggauc ucuuucgauc uaacaaucga auugaaccuu cagauuucag auuugauuag 120
gguuuuagcg ucuucggacc aggcuucauu ccccccaauu guugcucccu 170
//
ID ath-MIR166b standard; RNA; ATH; 120 BP.
XX
AC MI0000202;
XX
DE Arabidopsis thaliana miR166b stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
RN [7]
RX PUBMED; 24119003.
RA Vidal EA, Moyano TC, Krouk G, Katari MS, Tanurdzic M, McCombie WR, Coruzzi
RA GM, Gutierrez RA;
RT "Integrated RNA-seq and sRNA-seq analysis identifies novel
RT nitrate-responsive genes in Arabidopsis thaliana roots";
RL BMC Genomics. 14:701(2013).
XX
DR RFAM; RF00075; mir-166.
DR ASRP; ASRP934; miR166.
XX
CC MIR166b, like miR165, is thought to target mRNAs coding for HD-Zip
CC transcription factors including Phabulosa (PHB) and Phavoluta (PHV) that
CC regulate axillary meristem initiation and leaf development [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..27
FT /accession="MIMAT0031881"
FT /product="ath-miR166b-5p"
FT /evidence=experimental
FT /experiment="Illumina [7]"
FT miRNA 96..116
FT /accession="MIMAT0000190"
FT /product="ath-miR166b-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 5'RACE [3], 454
FT [4-5], MPSS [4], Illumina [6]"
XX
SQ Sequence 120 BP; 27 A; 25 C; 27 G; 0 T; 41 other;
uugaggggac uguugucugg cucgaggacu cuuauucuaa uacaaucuca uuugaauaca 60
uucagaucug augauugauu aggguuuuag ugucgucgga ccaggcuuca uuccccccaa 120
//
ID ath-MIR166c standard; RNA; ATH; 139 BP.
XX
AC MI0000203;
XX
DE Arabidopsis thaliana miR166c stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR RFAM; RF00075; mir-166.
DR ASRP; ASRP934; miR166.
XX
CC MIR166c, like miR165, is thought to target mRNAs coding for HD-Zip
CC transcription factors including Phabulosa (PHB) and Phavoluta (PHV) that
CC regulate axillary meristem initiation and leaf development [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 103..123
FT /accession="MIMAT0000191"
FT /product="ath-miR166c"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 5'RACE [3], 454
FT [4-5], MPSS [4], Illumina [6]"
XX
SQ Sequence 139 BP; 42 A; 28 C; 31 G; 0 T; 38 other;
gcgauuuagu guugagagga uuguugucug gcucgagguc augaagaaga gaaucacucg 60
aauuaauuug gaagaacaaa uuaagaaaac ccuagaugau ucucggacca ggcuucauuc 120
ccccuaaccu acuuaucgc 139
//
ID ath-MIR166d standard; RNA; ATH; 113 BP.
XX
AC MI0000204;
XX
DE Arabidopsis thaliana miR166d stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR RFAM; RF00075; mir-166.
DR ASRP; ASRP934; miR166.
XX
CC MIR166d, like miR165, is thought to target mRNAs coding for HD-Zip
CC transcription factors including Phabulosa (PHB) and Phavoluta (PHV) that
CC regulate axillary meristem initiation and leaf development [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 87..107
FT /accession="MIMAT0000192"
FT /product="ath-miR166d"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 5'RACE [3], 454
FT [4-5], MPSS [4], Illumina [6]"
XX
SQ Sequence 113 BP; 32 A; 23 C; 27 G; 0 T; 31 other;
gguugagagg aauauugucu ggcucgaggu caugaagaag aucgguagau ugauucauuu 60
uaaagaguga aaucccuaaa ugauucucgg accaggcuuc auucccccca acc 113
//
ID ath-MIR166e standard; RNA; ATH; 143 BP.
XX
AC MI0000205;
XX
DE Arabidopsis thaliana miR166e stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR RFAM; RF00075; mir-166.
DR ASRP; ASRP934; miR166.
XX
CC MIR166e, like miR165, is thought to target mRNAs coding for HD-Zip
CC transcription factors including Phabulosa (PHB) and Phavoluta (PHV) that
CC regulate axillary meristem initiation and leaf development [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..27
FT /accession="MIMAT0031882"
FT /product="ath-miR166e-5p"
FT /evidence=not_experimental
FT miRNA 119..139
FT /accession="MIMAT0000193"
FT /product="ath-miR166e-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 3'RACE [3], 454
FT [4-5], MPSS [4], Illumina [6]"
XX
SQ Sequence 143 BP; 36 A; 27 C; 26 G; 0 T; 54 other;
uugaggggaa uguugucugg cacgaggccc uuaacuuaga ucuauauuug auuauauaua 60
uaugucucuu cuuuauucau uagucuauac augaaugauc auuuuacggu uaaugacguc 120
ggaccaggcu ucauuccccu caa 143
//
ID ath-MIR166f standard; RNA; ATH; 105 BP.
XX
AC MI0000206;
XX
DE Arabidopsis thaliana miR166f stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR RFAM; RF00075; mir-166.
DR ASRP; ASRP934; miR166.
XX
CC MIR166f, like miR165, is thought to target mRNAs coding for HD-Zip
CC transcription factors including Phabulosa (PHB) and Phavoluta (PHV) that
CC regulate axillary meristem initiation and leaf development [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 78..98
FT /accession="MIMAT0000194"
FT /product="ath-miR166f"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 3'RACE [3], 454
FT [4-5], MPSS [4], Illumina [6]"
XX
SQ Sequence 105 BP; 28 A; 24 C; 22 G; 0 T; 31 other;
aaguucaggu gaaugaugcc uggcucgaga ccauucaauc ucaugaucuc augauuauaa 60
cgaugaugau gaugaugucg gaccaggcuu cauuccccuc aacuu 105
//
ID ath-MIR166g standard; RNA; ATH; 122 BP.
XX
AC MI0000207;
XX
DE Arabidopsis thaliana miR166g stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [4]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [5]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR RFAM; RF00075; mir-166.
DR ASRP; ASRP934; miR166.
XX
CC MIR166g, like miR165, is thought to target mRNAs coding for HD-Zip
CC transcription factors including Phabulosa (PHB) and Phavoluta (PHV) that
CC regulate axillary meristem initiation and leaf development [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 85..105
FT /accession="MIMAT0000195"
FT /product="ath-miR166g"
FT /evidence=experimental
FT /experiment="cloned [1], Northern [1], 454 [3-4], MPSS
FT [3], Illumina [5]"
XX
SQ Sequence 122 BP; 31 A; 27 C; 26 G; 0 T; 38 other;
gcgauuuagg guuuagagga auguuguuug gcucgagguc auggagagua auucguuaac 60
ccaacucaaa acucuaaaug auucucggac caggcuucau uccccucaac cuauuuuauc 120
gc 122
//
ID ath-MIR167a standard; RNA; ATH; 138 BP.
XX
AC MI0000208;
XX
DE Arabidopsis thaliana miR167a stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR ASRP; ASRP5; miR167.
XX
CC MIR167a is thought, like miR160, to target mRNAs coding for auxin response
CC factors, DNA binding proteins that are thought to control transcription in
CC response to the phytohormone auxin. Transcriptional regulation is
CC important for many of the diverse developmental responses to auxin
CC signals, which include cell elongation, division, and differentiation in
CC both roots and shoots [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 19..39
FT /accession="MIMAT0000196"
FT /product="ath-miR167a-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 5'RACE [3], 454
FT [4-5], MPSS [4], Illumina [6]"
FT miRNA 101..121
FT /accession="MIMAT0031883"
FT /product="ath-miR167a-3p"
FT /evidence=not_experimental
XX
SQ Sequence 138 BP; 28 A; 32 C; 31 G; 0 T; 47 other;
uggugcaccg gcaucugaug aagcugccag caugaucuaa uuagcuuucu uuauccuuug 60
uuguguuuca ugacgauggu uaagagauca gucucgauua gaucauguuc gcaguuucac 120
ccguugacug ucgcaccc 138
//
ID ath-MIR167b standard; RNA; ATH; 109 BP.
XX
AC MI0000209;
XX
DE Arabidopsis thaliana miR167b stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR ASRP; ASRP5; miR167.
XX
CC MIR167b is thought, like miR160, to target mRNAs coding for auxin response
CC factors, DNA binding proteins that are thought to control transcription in
CC response to the phytohormone auxin. Transcriptional regulation is
CC important for many of the diverse developmental responses to auxin
CC signals, which include cell elongation, division, and differentiation in
CC both roots and shoots [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 10..30
FT /accession="MIMAT0000197"
FT /product="ath-miR167b"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 5'RACE [3], 454
FT [4-5], MPSS [4], Illumina [6]"
XX
SQ Sequence 109 BP; 31 A; 25 C; 24 G; 0 T; 29 other;
gggaacaagu gaagcugcca gcaugaucua ucuuugguua agagaugaau guggaaacau 60
auugcuuaaa cccaagcuag gucaugcucu gacagccuca cuccuuccu 109
//
ID ath-MIR168a standard; RNA; ATH; 138 BP.
XX
AC MI0000210;
XX
DE Arabidopsis thaliana miR168a stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR ASRP; ASRP1429; miR168.
XX
CC MIR168a thought to target mRNAs coding for Argonaute (AGO1), which is
CC required for axillary shoot meristem formation and leaf development in
CC Arabidopsis. It has been suggested that AGO1 may also influence miRNA
CC accumulation in plants and that miR168 may act as a negative-feedback
CC mechanism for controlling expression of the AGO1 gene [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 18..38
FT /accession="MIMAT0000198"
FT /product="ath-miR168a-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 454 [4-5], MPSS
FT [4], Illumina [6]"
FT miRNA 103..123
FT /accession="MIMAT0031884"
FT /product="ath-miR168a-3p"
FT /evidence=not_experimental
XX
SQ Sequence 138 BP; 27 A; 35 C; 39 G; 0 T; 37 other;
caccaucggg cucggauucg cuuggugcag gucgggaacc aauucggcug acacagccuc 60
gugacuuuua aaccuuuauu gguuugugag cagggauugg aucccgccuu gcaucaacug 120
aaucggaucc ucgaggug 138
//
ID ath-MIR168b standard; RNA; ATH; 124 BP.
XX
AC MI0000211;
XX
DE Arabidopsis thaliana miR168b stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR ASRP; ASRP1429; miR168.
XX
CC MIR168b thought to target mRNAs coding for Argonaute (AGO1), which is
CC required for axillary shoot meristem formation and leaf development in
CC Arabidopsis. It has been suggested that AGO1 may also influence miRNA
CC accumulation in plants and that miR168 may act as a negative-feedback
CC mechanism for controlling expression of the AGO1 gene [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 19..39
FT /accession="MIMAT0000199"
FT /product="ath-miR168b-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 454 [4-5], MPSS
FT [4], Illumina [6]"
FT miRNA 89..109
FT /accession="MIMAT0031885"
FT /product="ath-miR168b-3p"
FT /evidence=not_experimental
XX
SQ Sequence 124 BP; 20 A; 28 C; 40 G; 0 T; 36 other;
uuaccggcgg ucucggauuc gcuuggugca ggucgggaac ugauuggcug acaccgacac 60
gugucuuguc augguugguu ugugagcucc cgucuuguau caacugaauc ggaguccgag 120
guga 124
//
ID ath-MIR169a standard; RNA; ATH; 226 BP.
XX
AC MI0000212;
XX
DE Arabidopsis thaliana miR169a stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR ASRP; ASRP1430; miR169.
XX
CC MIR169 is thought to target mRNAs coding for CCAAT binding factor
CC (CBF)-HAP2-like proteins [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 18..38
FT /accession="MIMAT0000200"
FT /product="ath-miR169a-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 5'RACE [3], 454
FT [4-5], MPSS [4], Illumina [6]"
FT miRNA 190..209
FT /accession="MIMAT0031886"
FT /product="ath-miR169a-3p"
FT /evidence=not_experimental
XX
SQ Sequence 226 BP; 75 A; 31 C; 39 G; 0 T; 81 other;
gugacgaaag uagugugcag ccaaggauga cuugccgauu uaaaugaucu uucuuuauac 60
ucuauuaaga caauuuaguu ucaaacuuuu uuuuuuuuuu uuuuuugaag gauucaggaa 120
gaaauuagga uauauuauuc cguauaaaau acaagauaua uaaaaccaaa aagaaaaagu 180
aacaugaucg gcaaguuguc cuuggcuaca cguuacuuug ugucgc 226
//
ID ath-MIR170 standard; RNA; ATH; 93 BP.
XX
AC MI0000213;
XX
DE Arabidopsis thaliana miR170 stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
DR ASRP; ASRP1431; miR170.
XX
CC MIR170 is thought to target mRNAs coding for GRAS domain or SCARECROW-like
CC proteins, a family of transcription factors whose members have been
CC implicated in radial patterning in roots, signaling by the phytohormone
CC gibberellin, and light signaling [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 18..38
FT /accession="MIMAT0031887"
FT /product="ath-miR170-5p"
FT /evidence=not_experimental
FT miRNA 59..79
FT /accession="MIMAT0000201"
FT /product="ath-miR170-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 5'RACE [3], 454
FT [4-5], MPSS [4]"
XX
SQ Sequence 93 BP; 18 A; 26 C; 17 G; 0 T; 32 other;
cgagagaguc ccucugauau uggccugguu cacucagauu cucuuuuacu aacucaucug 60
auugagccgu gucaauaucu caguccucuc ucg 93
//
ID ath-MIR171a standard; RNA; ATH; 123 BP.
XX
AC MI0000214;
XX
DE Arabidopsis thaliana miR171a stem-loop
XX
RN [1]
RX PUBMED; 12101121.
RA Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP;
RT "MicroRNAs in plants";
RL Genes Dev. 16:1616-1626(2002).
XX
RN [2]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR ASRP; ASRP39; miR171.
XX
CC MIR171 is thought, like miR170, to target mRNAs coding for GRAS domain or
CC SCARECROW-like proteins, a family of transcription factors whose members
CC have been implicated in radial patterning in roots, signaling by the
CC phytohormone gibberellin, and light signaling [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 19..39
FT /accession="MIMAT0031888"
FT /product="ath-miR171a-5p"
FT /evidence=not_experimental
FT miRNA 88..108
FT /accession="MIMAT0000202"
FT /product="ath-miR171a-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], 5'RACE [3], 454
FT [4-5], MPSS [4], Illumina [6]"
XX
SQ Sequence 123 BP; 30 A; 32 C; 21 G; 0 T; 40 other;
augagagagu cccuuugaua uuggccuggu ucacucagau cuuaccugac cacacacgua 60
gauauacauu auucucucua gauuaucuga uugagccgcg ccaauaucuc aguacucucu 120
cgu 123
//
ID ath-MIR172a standard; RNA; ATH; 102 BP.
XX
AC MI0000215;
XX
DE Arabidopsis thaliana miR172a stem-loop
XX
RN [1]
RX PUBMED; 12225663.
RA Park W, Li J, Song R, Messing J, Chen X;
RT "CARPEL FACTORY, a Dicer homolog, and HEN1, a novel protein, act in
RT microRNA metabolism in Arabidopsis thaliana";
RL Curr Biol. 12:1484-1495(2002).
XX
RN [2]
RX PUBMED; 12226481.
RA Mette MF, van der Winden J, Matzke M, Matzke AJ;
RT "Short RNAs can identify new candidate transposable element families in
RT Arabidopsis";
RL Plant Physiol. 130:6-9(2002).
XX
RN [3]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [4]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [5]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [6]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR ASRP; ASRP1432; miR172.
XX
CC This sequence was independently identified by two groups. Park et al.
CC described miR172a1, found on chromosome 2 in Arabidopsis thaliana and
CC thought to target mRNAs coding for Apetala 2 (AP2) proteins, and miR172a2
CC (MIR:MI0000216) [1]. These sequences have been renamed miR172a and
CC miR172b here to match previous plant miRNA nomenclature. This sequence
CC was referred to by Mette et al. by the internal identifier MIR123a [2],
CC and was previously identified as MIR180a here. This sequence is not
CC related to mouse miR-123.
XX
FH Key Location/Qualifiers
FH
FT miRNA 78..98
FT /accession="MIMAT0000203"
FT /product="ath-miR172a"
FT /evidence=experimental
FT /experiment="cloned [1-2], 5'RACE [3], 454 [4-5], MPSS
FT [4], Illumina [6]"
XX
SQ Sequence 102 BP; 26 A; 21 C; 24 G; 0 T; 31 other;
ugcuguggca ucaucaagau ucacaucugu ugauggacgg uggugauuca cucuccacaa 60
aguucucuau gaaaaugaga aucuugauga ugcugcaucg gc 102
//
ID ath-MIR172b standard; RNA; ATH; 95 BP.
XX
AC MI0000216;
XX
DE Arabidopsis thaliana miR172b stem-loop
XX
RN [1]
RX PUBMED; 12225663.
RA Park W, Li J, Song R, Messing J, Chen X;
RT "CARPEL FACTORY, a Dicer homolog, and HEN1, a novel protein, act in
RT microRNA metabolism in Arabidopsis thaliana";
RL Curr Biol. 12:1484-1495(2002).
XX
RN [2]
RX PUBMED; 12226481.
RA Mette MF, van der Winden J, Matzke M, Matzke AJ;
RT "Short RNAs can identify new candidate transposable element families in
RT Arabidopsis";
RL Plant Physiol. 130:6-9(2002).
XX
RN [3]
RX PUBMED; 15345049.
RA Wang XJ, Reyes JL, Chua NH, Gaasterland T;
RT "Prediction and identification of Arabidopsis thaliana microRNAs and their
RT mRNA targets";
RL Genome Biol. 5:R65(2004).
XX
RN [4]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [5]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [6]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [7]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR ASRP; ASRP1432; miR172.
XX
CC This sequence was independently identified by two groups. Park et al.
CC described miR172a2, found on chromosome 5 in Arabidopsis thaliana and
CC thought to target mRNAs coding for Apetala 2 (AP2) proteins, and miR172a1
CC (MIR:MI0000215) [1]. These sequences have been renamed miR172b and
CC miR172a here to match previous plant miRNA nomenclature. This sequence
CC was referred to by Mette et al. by the internal identifier MIR123b [2],
CC and was previously identified as MIR180b here. This sequence is not
CC related to mouse miR-123. Wang et al. [2] report Northern blot evidence
CC for the miR172b* sequence from the opposite arm of the precursor.
XX
FH Key Location/Qualifiers
FH
FT miRNA 5..24
FT /accession="MIMAT0000204"
FT /product="ath-miR172b-5p"
FT /evidence=experimental
FT /experiment="Northern [3], 454 [6]"
FT miRNA 71..91
FT /accession="MIMAT0000205"
FT /product="ath-miR172b-3p"
FT /evidence=experimental
FT /experiment="cloned [1], 5'RACE [4], 454 [5-6], MPSS [5],
FT Illumina [7]"
XX
SQ Sequence 95 BP; 33 A; 15 C; 19 G; 0 T; 28 other;
aggcgcagca ccauuaagau ucacauggaa auugauaaau acccuaaauu aggguuuuga 60
uauguauaug agaaucuuga ugaugcugca ucaac 95
//
ID ath-MIR173 standard; RNA; ATH; 102 BP.
XX
AC MI0000217;
XX
DE Arabidopsis thaliana miR173 stem-loop
XX
RN [1]
RX PUBMED; 12225663.
RA Park W, Li J, Song R, Messing J, Chen X;
RT "CARPEL FACTORY, a Dicer homolog, and HEN1, a novel protein, act in
RT microRNA metabolism in Arabidopsis thaliana";
RL Curr Biol. 12:1484-1495(2002).
XX
RN [2]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [3]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [4]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [5]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
RN [6]
RX PUBMED; 22221297.
RA Zhang B, Xie D, Jin Z;
RT "Global analysis of non-coding small RNAs in Arabidopsis in response to
RT jasmonate treatment by deep sequencing technology";
RL J Integr Plant Biol. 54:73-86(2012).
XX
DR ASRP; ASRP886; miR173.
XX
CC MIR173 is thought to target mRNAs coding for a protein of unknown function
CC (At3g28460) [1].
XX
FH Key Location/Qualifiers
FH
FT miRNA 9..30
FT /accession="MIMAT0000206"
FT /product="ath-miR173-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], 454 [3-4], MPSS [3], Illumina
FT [5]"
FT miRNA 75..95
FT /accession="MIMAT0022843"
FT /product="ath-miR173-3p"
FT /evidence=experimental
FT /experiment="Illumina [6]"
XX
SQ Sequence 102 BP; 28 A; 17 C; 22 G; 0 T; 35 other;
uaaguacuuu cgcuugcaga gagaaaucac aguggucaaa aaaguuguag uuuucuuaaa 60
gucucuuucc ucugugauuc ucuguguaag cgaaagagcu ug 102
//
ID ath-MIR159b standard; RNA; ATH; 196 BP.
XX
AC MI0000218;
XX
DE Arabidopsis thaliana miR159b stem-loop
XX
RN [1]
RX PUBMED; 12226481.
RA Mette MF, van der Winden J, Matzke M, Matzke AJ;
RT "Short RNAs can identify new candidate transposable element families in
RT Arabidopsis";
RL Plant Physiol. 130:6-9(2002).
XX
RN [2]
RX PUBMED; 12225663.
RA Park W, Li J, Song R, Messing J, Chen X;
RT "CARPEL FACTORY, a Dicer homolog, and HEN1, a novel protein, act in
RT microRNA metabolism in Arabidopsis thaliana";
RL Curr Biol. 12:1484-1495(2002).
XX
RN [3]
RX PUBMED; 12202040.
RA Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP;
RT "Prediction of plant microRNA targets";
RL Cell. 110:513-520(2002).
XX
RN [4]
RX PUBMED; 16040653.
RA Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC;
RT "Expression of Arabidopsis MIRNA genes";
RL Plant Physiol. 138:2145-2154(2005).
XX
RN [5]
RX PUBMED; 16954541.
RA Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS,
RA Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC;
RT "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent
RT RNA polymerase-2 mutant";
RL Genome Res. 16:1276-1288(2006).
XX
RN [6]
RX PUBMED; 17182867.
RA Rajagopalan R, Vaucheret H, Trejo J, Bartel DP;
RT "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis
RT thaliana";
RL Genes Dev. 20:3407-3425(2006).
XX
RN [7]
RX PUBMED; 19815687.
RA Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW;
RT "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in
RT Arabidopsis";
RL J Exp Bot. 61:165-177(2010).
XX
DR ASRP; ASRP1747; miR159.
XX
CC Reference [1] described the discovery of MIR159b, but referred to the
CC sequence by the internal identifier MIR40b. This sequence is not related
CC to C. elegans miR-40. MIR159b is found on chromosome 1 in Arabidopsis
CC thaliana [2] and is thought to target mRNAs coding for MYB proteins which
CC are known to bind to the promoter of the floral meristem identity gene
CC LEAFY [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 5..25
FT /accession="MIMAT0031889"
FT /product="ath-miR159b-5p"
FT /evidence=not_experimental
FT miRNA 168..188
FT /accession="MIMAT0000207"
FT /product="ath-miR159b-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2,4], 5'RACE [4], 454 [5-6], MPSS
FT [5], Illumina [7]"
XX
SQ Sequence 196 BP; 51 A; 37 C; 42 G; 0 T; 66 other;
ggaagagcuc cuugaaguuc aauggagggu uuagcagggu gaaguaaagc ugcuaagcua 60
uggaucccau aagccuuauc aaauucaaua uaauugauga uaagguuuuu uuuauggaug 120
ccauaucuca ggagcuuuca cuuaccccuu uaauggcuuc acucuucuuu ggauugaagg 180
gagcucuuca ucucuc 196
//
ID mmu-mir-10b standard; RNA; MMU; 68 BP.
XX
AC MI0000221;
XX
DE Mus musculus miR-10b stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR RFAM; RF00104; mir-10.
DR MGI; 2676804; Mir10b.
DR ENTREZGENE; 387144; Mir10b.
XX
CC The sequence of mouse miR-10b, as reported by Lagos-Quintana et al. [1],
CC is offset by 2 nt in the 3' direction with respect to sequences cloned
CC from human (MIR:MI0000267) and zebrafish (MIR:MI0001364). The mature
CC sequence shown here represents the most commonly cloned form from
CC large-scale cloning studies [2]. The 5' end of the miRNA may be offset
CC with respect to previous annotations.
XX
FH Key Location/Qualifiers
FH
FT miRNA 5..27
FT /accession="MIMAT0000208"
FT /product="mmu-miR-10b-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Illumina [3-4]"
FT miRNA 45..66
FT /accession="MIMAT0004538"
FT /product="mmu-miR-10b-3p"
FT /evidence=experimental
FT /experiment="cloned [2], Illumina [3-4]"
XX
SQ Sequence 68 BP; 21 A; 13 C; 14 G; 0 T; 20 other;
uauauacccu guagaaccga auuugugugg uacccacaua gucacagauu cgauucuagg 60
ggaauaua 68
//
ID mmu-mir-129-1 standard; RNA; MMU; 73 BP.
XX
AC MI0000222;
XX
DE Mus musculus miR-129-1 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [3]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [6]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676815; Mir129-1.
DR ENTREZGENE; 387237; Mir129-1.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [4].
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..26
FT /accession="MIMAT0000209"
FT /product="mmu-miR-129-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3-4], Illumina [5-6]"
FT miRNA 49..70
FT /accession="MIMAT0016994"
FT /product="mmu-miR-129-1-3p"
FT /evidence=experimental
FT /experiment="Illumina [6]"
XX
SQ Sequence 73 BP; 15 A; 18 C; 17 G; 0 T; 23 other;
uggaucuuuu ugcggucugg gcuugcuguu cucucgacag uagucaggaa gcccuuaccc 60
caaaaaguau cua 73
//
ID mmu-mir-181a-2 standard; RNA; MMU; 76 BP.
XX
AC MI0000223;
XX
DE Mus musculus miR-181a-2 stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [3]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [4]
RX PUBMED; 15634332.
RA Weber MJ;
RT "New human and mouse microRNA genes found by homology search";
RL FEBS J. 272:59-73(2005).
XX
RN [5]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [6]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [7]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676845; Mir181a-2.
DR ENTREZGENE; 387176; Mir181a-2.
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..29
FT /accession="MIMAT0000210"
FT /product="mmu-miR-181a-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3,5], Illumina [6-7]"
FT miRNA 51..72
FT /accession="MIMAT0005443"
FT /product="mmu-miR-181a-2-3p"
FT /evidence=experimental
FT /experiment="cloned [5], Illumina [6-7]"
XX
SQ Sequence 76 BP; 24 A; 18 C; 17 G; 0 T; 17 other;
ccauggaaca uucaacgcug ucggugaguu ugggauucaa aaacaaaaaa accaccgacc 60
guugacugua ccuugg 76
//
ID mmu-mir-182 standard; RNA; MMU; 75 BP.
XX
AC MI0000224;
XX
DE Mus musculus miR-182 stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [5]
RX PUBMED; 20668074.
RA Zhu JY, Strehle M, Frohn A, Kremmer E, Hofig KP, Meister G, Adler H;
RT "Identification and analysis of expression of novel microRNAs of murine
RT gammaherpesvirus 68";
RL J Virol. 84:10266-10275(2010).
XX
RN [6]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676846; Mir182.
DR ENTREZGENE; 387177; Mir182.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..31
FT /accession="MIMAT0000211"
FT /product="mmu-miR-182-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Illumina [4,6]"
FT miRNA 50..70
FT /accession="MIMAT0016995"
FT /product="mmu-miR-182-3p"
FT /evidence=experimental
FT /experiment="454 [5], Illumina [6]"
XX
SQ Sequence 75 BP; 19 A; 16 C; 20 G; 0 T; 20 other;
accauuuuug gcaaugguag aacucacacc gguaagguaa ugggacccgg ugguucuaga 60
cuugccaacu auggu 75
//
ID mmu-mir-183 standard; RNA; MMU; 70 BP.
XX
AC MI0000225;
XX
DE Mus musculus miR-183 stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [5]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676847; Mir183.
DR ENTREZGENE; 387178; Mir183.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..27
FT /accession="MIMAT0000212"
FT /product="mmu-miR-183-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Illumina [4-5]"
FT miRNA 45..66
FT /accession="MIMAT0004539"
FT /product="mmu-miR-183-3p"
FT /evidence=experimental
FT /experiment="cloned [3], Illumina [4-5]"
XX
SQ Sequence 70 BP; 21 A; 14 C; 18 G; 0 T; 17 other;
cuguguaugg cacugguaga auucacugug aacagucuca gucagugaau uaccgaaggg 60
ccauaaacag 70
//
ID mmu-mir-184 standard; RNA; MMU; 69 BP.
XX
AC MI0000226;
XX
DE Mus musculus miR-184 stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676848; Mir184.
DR ENTREZGENE; 387179; Mir184.
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..27
FT /accession="MIMAT0022690"
FT /product="mmu-miR-184-5p"
FT /evidence=not_experimental
FT miRNA 45..66
FT /accession="MIMAT0000213"
FT /product="mmu-miR-184-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Illumina [3-4]"
XX
SQ Sequence 69 BP; 15 A; 15 C; 17 G; 0 T; 22 other;
ccuuuccuua ucacuuuucc agccagcuuu gugacucuaa guguuggacg gagaacugau 60
aaggguagg 69
//
ID mmu-mir-185 standard; RNA; MMU; 65 BP.
XX
AC MI0000227;
XX
DE Mus musculus miR-185 stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676849; Mir185.
DR ENTREZGENE; 387180; Mir185.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..28
FT /accession="MIMAT0000214"
FT /product="mmu-miR-185-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Illumina [3-4]"
FT miRNA 41..61
FT /accession="MIMAT0016996"
FT /product="mmu-miR-185-3p"
FT /evidence=experimental
FT /experiment="Illumina [4]"
XX
SQ Sequence 65 BP; 10 A; 17 C; 21 G; 0 T; 17 other;
agggauugga gagaaaggca guuccugaug guccccuccc aggggcuggc uuuccucugg 60
uccuu 65
//
ID mmu-mir-186 standard; RNA; MMU; 71 BP.
XX
AC MI0000228;
XX
DE Mus musculus miR-186 stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [5]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676850; Mir186.
DR ENTREZGENE; 387181; Mir186.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..28
FT /accession="MIMAT0000215"
FT /product="mmu-miR-186-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Illumina [4-5]"
FT miRNA 46..67
FT /accession="MIMAT0004540"
FT /product="mmu-miR-186-3p"
FT /evidence=experimental
FT /experiment="cloned [3], Illumina [4-5]"
XX
SQ Sequence 71 BP; 16 A; 12 C; 12 G; 0 T; 31 other;
acuuuccaaa gaauucuccu uuugggcuuu cucauuuuau uuuaagcccu aaggugaauu 60
uuuugggaag u 71
//
ID mmu-mir-187 standard; RNA; MMU; 61 BP.
XX
AC MI0000229;
XX
DE Mus musculus miR-187 stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676851; Mir187.
DR ENTREZGENE; 387182; Mir187.
XX
FH Key Location/Qualifiers
FH
FT miRNA 3..24
FT /accession="MIMAT0016997"
FT /product="mmu-miR-187-5p"
FT /evidence=experimental
FT /experiment="Illumina [4]"
FT miRNA 40..61
FT /accession="MIMAT0000216"
FT /product="mmu-miR-187-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Illumina [3-4]"
XX
SQ Sequence 61 BP; 9 A; 21 C; 18 G; 0 T; 13 other;
ucaggcuaca acacaggacc cgggcgcugc ucugaccccu cgugucuugu guugcagccg 60
g 61
//
ID mmu-mir-188 standard; RNA; MMU; 68 BP.
XX
AC MI0000230;
XX
DE Mus musculus miR-188 stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [5]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676852; Mir188.
DR ENTREZGENE; 387183; Mir188.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..26
FT /accession="MIMAT0000217"
FT /product="mmu-miR-188-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Illumina [4-5]"
FT miRNA 45..65
FT /accession="MIMAT0004541"
FT /product="mmu-miR-188-3p"
FT /evidence=experimental
FT /experiment="cloned [3], Illumina [4-5]"
XX
SQ Sequence 68 BP; 14 A; 20 C; 18 G; 0 T; 16 other;
ucucacaucc cuugcauggu ggagggugag cucucugaaa accccuccca caugcagggu 60
uugcagga 68
//
ID mmu-mir-24-1 standard; RNA; MMU; 68 BP.
XX
AC MI0000231;
XX
DE Mus musculus miR-24-1 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [3]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [4]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
XX
RN [5]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [6]
RX PUBMED; 16766679.
RA Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N,
RA Imai H;
RT "Identification and characterization of two novel classes of small RNAs in
RT the mouse germline: retrotransposon-derived siRNAs in oocytes and germline
RT small RNAs in testes";
RL Genes Dev. 20:1732-1743(2006).
XX
RN [7]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [8]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [9]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676899; Mir24-1.
DR ENTREZGENE; 387142; Mir24-1.
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..28
FT /accession="MIMAT0000218"
FT /product="mmu-miR-24-1-5p"
FT /evidence=experimental
FT /experiment="cloned [2,7], Illumina [8-9]"
FT miRNA 44..65
FT /accession="MIMAT0000219"
FT /product="mmu-miR-24-3p"
FT /evidence=experimental
FT /experiment="cloned [1,3,5-7], Northern [3], Illumina [8]"
XX
SQ Sequence 68 BP; 16 A; 19 C; 16 G; 0 T; 17 other;
cuccggugcc uacugagcug auaucaguuc ucauuucaca cacuggcuca guucagcagg 60
aacaggag 68
//
ID mmu-mir-190a standard; RNA; MMU; 67 BP.
XX
AC MI0000232;
XX
DE Mus musculus miR-190 stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20668074.
RA Zhu JY, Strehle M, Frohn A, Kremmer E, Hofig KP, Meister G, Adler H;
RT "Identification and analysis of expression of novel microRNAs of murine
RT gammaherpesvirus 68";
RL J Virol. 84:10266-10275(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676854; Mir190.
DR ENTREZGENE; 387185; Mir190.
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..27
FT /accession="MIMAT0000220"
FT /product="mmu-miR-190a-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Illumina [4]"
FT miRNA 42..63
FT /accession="MIMAT0016998"
FT /product="mmu-miR-190a-3p"
FT /evidence=experimental
FT /experiment="454 [3], Illumina [4]"
XX
SQ Sequence 67 BP; 20 A; 9 C; 10 G; 0 T; 28 other;
cugugugaua uguuugauau auuagguugu uauuuaaucc aacuauauau caagcauauu 60
ccuacag 67
//
ID mmu-mir-191 standard; RNA; MMU; 74 BP.
XX
AC MI0000233;
XX
DE Mus musculus miR-191 stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [3]
RX PUBMED; 16766679.
RA Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N,
RA Imai H;
RT "Identification and characterization of two novel classes of small RNAs in
RT the mouse germline: retrotransposon-derived siRNAs in oocytes and germline
RT small RNAs in testes";
RL Genes Dev. 20:1732-1743(2006).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [6]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676855; Mir191.
DR ENTREZGENE; 387186; Mir191.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [4].
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..29
FT /accession="MIMAT0000221"
FT /product="mmu-miR-191-5p"
FT /evidence=experimental
FT /experiment="cloned [1-4], Illumina [5-6]"
FT miRNA 49..70
FT /accession="MIMAT0004542"
FT /product="mmu-miR-191-3p"
FT /evidence=experimental
FT /experiment="cloned [4], Illumina [5-6]"
XX
SQ Sequence 74 BP; 16 A; 22 C; 18 G; 0 T; 18 other;
agcgggcaac ggaaucccaa aagcagcugu ugucuccaga gcauuccagc ugcacuugga 60
uuucguuccc ugcu 74
//
ID hsa-mir-192 standard; RNA; HSA; 110 BP.
XX
AC MI0000234;
XX
DE Homo sapiens miR-192 stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [3]
RX PUBMED; 14573789.
RA Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ;
RT "Reduced accumulation of specific microRNAs in colorectal neoplasia";
RL Mol Cancer Res. 1:882-891(2003).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-192; hsa-miR-192.
DR HGNC; 31562; MIR192.
DR ENTREZGENE; 406967; MIR192.
XX
CC Lagos-Quintana et al. validated the presence of an 18 nt excised sequence
CC by cloning [1]. Lim et al. predicted the miR by computational methods
CC using conservation with mouse and Fugu rubripes sequences. Expression of
CC the excised miR was validated in zebrafish, and the 5' end mapped by PCR
CC [2]. The 3' ends of the reported sequences differ by 3 nt - this entry
CC contains the longer sequence. Lim et al. report three separate copies of
CC this gene named mir-192-1, -2 and -3 based on 2001 human genome assemblies
CC [2]. Subsequent assemblies suggest the presence of only one gene located
CC on chromosome 11.
XX
FH Key Location/Qualifiers
FH
FT miRNA 24..44
FT /accession="MIMAT0000222"
FT /product="hsa-miR-192-5p"
FT /evidence=experimental
FT /experiment="cloned [3-4]"
FT miRNA 67..88
FT /accession="MIMAT0004543"
FT /product="hsa-miR-192-3p"
FT /evidence=experimental
FT /experiment="cloned [4]"
XX
SQ Sequence 110 BP; 22 A; 36 C; 27 G; 0 T; 25 other;
gccgagaccg agugcacagg gcucugaccu augaauugac agccagugcu cucgucuccc 60
cucuggcugc caauuccaua ggucacaggu auguucgccu caaugccagc 110
//
ID mmu-mir-193a standard; RNA; MMU; 66 BP.
XX
AC MI0000235;
XX
DE Mus musculus miR-193 stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [5]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676857; Mir193.
DR ENTREZGENE; 387188; Mir193.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..28
FT /accession="MIMAT0004544"
FT /product="mmu-miR-193a-5p"
FT /evidence=experimental
FT /experiment="cloned [3], Illumina [4-5]"
FT miRNA 41..62
FT /accession="MIMAT0000223"
FT /product="mmu-miR-193a-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Northern [2], Illumina [4-5]"
XX
SQ Sequence 66 BP; 15 A; 16 C; 20 G; 0 T; 15 other;
gagagcuggg ucuuugcggg caagaugaga gugucaguuc aacuggccua caaaguccca 60
guccuc 66
//
ID mmu-mir-194-1 standard; RNA; MMU; 67 BP.
XX
AC MI0000236;
XX
DE Mus musculus miR-194-1 stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 14573789.
RA Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ;
RT "Reduced accumulation of specific microRNAs in colorectal neoplasia";
RL Mol Cancer Res. 1:882-891(2003).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [5]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676858; Mir194-1.
DR ENTREZGENE; 387189; Mir194-1.
XX
CC Lagos-Quintana cloned miR-194 from mouse kidney tissue [1]. Michael et
CC al. subsequently verified expression of miR-194 in human [2]. Two
CC putative pairs of orthologous hairpin precursors structures are found in
CC mouse (mir-194-1 (MIR:MI0000236) on chromosome 1, and mir-194-2
CC (MIR:MI0000733) on chromosome 19) and human (mir-194-1 (MIR:MI0000488) on
CC chromosome 1, and mir-194-2 (MIR:MI0000732) on chromosome 11).
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..28
FT /accession="MIMAT0000224"
FT /product="mmu-miR-194-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Illumina [4-5]"
FT miRNA 42..63
FT /accession="MIMAT0016999"
FT /product="mmu-miR-194-1-3p"
FT /evidence=experimental
FT /experiment="Illumina [5]"
XX
SQ Sequence 67 BP; 13 A; 15 C; 19 G; 0 T; 20 other;
aucgggugua acagcaacuc cauguggacu gugcucggau uccaguggag cugcuguuac 60
uucugau 67
//
ID mmu-mir-195a standard; RNA; MMU; 94 BP.
XX
AC MI0000237;
XX
DE Mus musculus miR-195 stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [5]
RX PUBMED; 20668074.
RA Zhu JY, Strehle M, Frohn A, Kremmer E, Hofig KP, Meister G, Adler H;
RT "Identification and analysis of expression of novel microRNAs of murine
RT gammaherpesvirus 68";
RL J Virol. 84:10266-10275(2010).
XX
RN [6]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676859; Mir195.
DR ENTREZGENE; 387190; Mir195.
XX
FH Key Location/Qualifiers
FH
FT miRNA 21..41
FT /accession="MIMAT0000225"
FT /product="mmu-miR-195a-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Illumina [4,6]"
FT miRNA 59..80
FT /accession="MIMAT0017000"
FT /product="mmu-miR-195a-3p"
FT /evidence=experimental
FT /experiment="454 [5], Illumina [6]"
XX
SQ Sequence 94 BP; 22 A; 23 C; 28 G; 0 T; 21 other;
acacccaacu cuccuggcuc uagcagcaca gaaauauugg cauggggaag ugagucugcc 60
aauauuggcu gugcugcucc aggcagggug guga 94
//
ID hsa-mir-196a-1 standard; RNA; HSA; 70 BP.
XX
AC MI0000238;
XX
DE Homo sapiens miR-196a-1 stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [3]
RX PUBMED; 15105502.
RA Yekta S, Shih IH, Bartel DP;
RT "MicroRNA-directed cleavage of HOXB8 mRNA";
RL Science. 304:594-596(2004).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-196a; hsa-miR-196a.
DR HGNC; 31567; MIR196A1.
DR ENTREZGENE; 406972; MIR196A1.
XX
CC Lagos-Quintana et al. [1] cloned this miRNA from human osteoblast sarcoma
CC cells. Lim et al [2] independently predicted this miRNA by computational
CC methods using conservation with mouse and Fugu rubripes sequences [2].
CC Expression of the excised miR was validated in zebrafish. The sequence
CC maps to human chromosome 17. Yekta et al. report that miR-196 miRNAs are
CC expressed from HOX gene clusters in mammals, and that HOX genes in these
CC clusters are targets of miR-196. Indeed, HOXB8 mRNA was shown to be a
CC natural target for miR-196-directed cleavage through a perfectly
CC complementary miR-target site. Other HOX genes have imperfect miR-196
CC complementary sites indicative of regulation by translational repression
CC [3]. The mature sequence shown here represents the most commonly cloned
CC form from large-scale cloning studies [4].
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..28
FT /accession="MIMAT0000226"
FT /product="hsa-miR-196a-5p"
FT /evidence=experimental
FT /experiment="cloned [1,4-5]"
FT miRNA 45..65
FT /accession="MIMAT0037307"
FT /product="hsa-miR-196a-1-3p"
FT /evidence=not_experimental
XX
SQ Sequence 70 BP; 19 A; 15 C; 15 G; 0 T; 21 other;
gugaauuagg uaguuucaug uuguugggcc uggguuucug aacacaacaa cauuaaacca 60
cccgauucac 70
//
ID hsa-mir-197 standard; RNA; HSA; 75 BP.
XX
AC MI0000239;
XX
DE Homo sapiens miR-197 stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-197; hsa-miR-197.
DR HGNC; 31569; MIR197.
DR ENTREZGENE; 406974; MIR197.
XX
FH Key Location/Qualifiers
FH
FT miRNA 9..31
FT /accession="MIMAT0022691"
FT /product="hsa-miR-197-5p"
FT /evidence=not_experimental
FT miRNA 48..69
FT /accession="MIMAT0000227"
FT /product="hsa-miR-197-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3]"
XX
SQ Sequence 75 BP; 14 A; 24 C; 23 G; 0 T; 14 other;
ggcugugccg gguagagagg gcagugggag guaagagcuc uucacccuuc accaccuucu 60
ccacccagca uggcc 75
//
ID hsa-mir-198 standard; RNA; HSA; 62 BP.
XX
AC MI0000240;
XX
DE Homo sapiens miR-198 stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-198; hsa-miR-198.
DR HGNC; 31570; MIR198.
DR ENTREZGENE; 406975; MIR198.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..27
FT /accession="MIMAT0000228"
FT /product="hsa-miR-198"
FT /evidence=experimental
FT /experiment="cloned [1-2]"
XX
SQ Sequence 62 BP; 15 A; 10 C; 14 G; 0 T; 23 other;
ucauuggucc agaggggaga uagguuccug ugauuuuucc uucuucucua uagaauaaau 60
ga 62
//
ID mmu-mir-199a-1 standard; RNA; MMU; 70 BP.
XX
AC MI0000241;
XX
DE Mus musculus miR-199a-1 stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [3]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [6]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676863; Mir199a-1.
DR ENTREZGENE; 387194; Mir199a-1.
XX
CC The hairpin precursor sequence mir-199 maps to two loci within 50 kb on
CC mouse chromosome 9. This sequence was named mir-199 in [1] and [2], but
CC is renamed here to avoid overlap with the predicted homologues of human
CC mir-199a-2 and mir-199b. Landgraf et al. demonstrate comparable
CC expression for products from both arms of the hairpin, which are therefore
CC renamed miR-199a-5p and miR-199a-3p here [4]. The mature sequences shown
CC here represent the most commonly cloned forms from large-scale cloning
CC studies [4]. The 5' end of the miRNA may be offset with respect to
CC previous annotations.
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..28
FT /accession="MIMAT0000229"
FT /product="mmu-miR-199a-5p"
FT /evidence=experimental
FT /experiment="cloned [2,4], Northern [2], Illumina [5-6]"
FT miRNA 46..67
FT /accession="MIMAT0000230"
FT /product="mmu-miR-199a-3p"
FT /evidence=experimental
FT /experiment="cloned [1-4], Northern [2], Illumina [5-6]"
XX
SQ Sequence 70 BP; 15 A; 17 C; 20 G; 0 T; 18 other;
gccaucccag uguucagacu accuguucag gaggcuggga cauguacagu agucugcaca 60
uugguuaggc 70
//
ID hsa-mir-199a-1 standard; RNA; HSA; 71 BP.
XX
AC MI0000242;
XX
DE Homo sapiens miR-199a-1 stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [3]
RX PUBMED; 15978578.
RA Fu H, Tie Y, Xu C, Zhang Z, Zhu J, Shi Y, Jiang H, Sun Z, Zheng X;
RT "Identification of human fetal liver miRNAs by a novel method";
RL FEBS Lett. 579:3849-3854(2005).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 20158877.
RA Koh W, Sheng CT, Tan B, Lee QY, Kuznetsov V, Kiang LS, Tanavde V;
RT "Analysis of deep sequencing microRNA expression profile from human
RT embryonic stem cells derived mesenchymal stem cells reveals possible role
RT of let-7 microRNA family in downstream targeting of hepatic nuclear factor
RT 4 alpha";
RL BMC Genomics. 11 Suppl 1:S6(2010).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-199a; hsa-miR-199a.
DR TARGETS:PICTAR-VERT; hsa-miR-199a*; hsa-miR-199a*.
DR HGNC; 31571; MIR199A1.
DR ENTREZGENE; 406976; MIR199A1.
XX
CC Lagos-Quintana et al. [1] cloned miR-199 from human osteoblast sarcoma
CC cells. They also reported identification of a miRNA from the opposite arm
CC in mouse cells. This sequence was named miR-199-s and the sequence from
CC the 3' arm of the homologous mouse precursor miR-199-as. Lim et al. [2]
CC independently predicted this miRNA computationally using conservation with
CC mouse and Fugu rubripes sequences [2]. Expression of the miR excised from
CC the 5' arm was validated in zebrafish, and the ends mapped by cloning. The
CC excised miR sequences are renamed miR-199a (to avoid confusion with the
CC subsequently identified miR-199b (MIR:MI0000282)) and miR-199a* (from the
CC 3' arm) here. The two putative hairpin precursors in human map to
CC chromosome 19 (mir-199a-1, MIR:MI0000242) and chromosome 1 (mir-199a-2,
CC MIR:MI0000281). Landgraf et al. show that both mature products are
CC expressed, prompting the renaming to miR-199a-5p and miR-199a-3p [4].
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..28
FT /accession="MIMAT0000231"
FT /product="hsa-miR-199a-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3-4]"
FT miRNA 47..68
FT /accession="MIMAT0000232"
FT /product="hsa-miR-199a-3p"
FT /evidence=experimental
FT /experiment="cloned [4], Illumina [5]"
FT /similarity="MI0000713"
XX
SQ Sequence 71 BP; 16 A; 18 C; 18 G; 0 T; 19 other;
gccaacccag uguucagacu accuguucag gaggcucuca auguguacag uagucugcac 60
auugguuagg c 71
//
ID mmu-mir-200b standard; RNA; MMU; 70 BP.
XX
AC MI0000243;
XX
DE Mus musculus miR-200b stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676875; Mir200b.
DR ENTREZGENE; 387243; Mir200b.
XX
FH Key Location/Qualifiers
FH
FT miRNA 9..30
FT /accession="MIMAT0004545"
FT /product="mmu-miR-200b-5p"
FT /evidence=experimental
FT /experiment="cloned [2], Illumina [3-4]"
FT miRNA 45..66
FT /accession="MIMAT0000233"
FT /product="mmu-miR-200b-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Illumina [3-4]"
XX
SQ Sequence 70 BP; 14 A; 16 C; 20 G; 0 T; 20 other;
gccguggcca ucuuacuggg cagcauugga uagugucuga ucucuaauac ugccugguaa 60
ugaugacggc 70
//
ID mmu-mir-201 standard; RNA; MMU; 66 BP.
XX
AC MI0000244;
XX
DE Mus musculus miR-201 stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676876; Mir201.
DR ENTREZGENE; 387197; Mir201.
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..27
FT /accession="MIMAT0000234"
FT /product="mmu-miR-201-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Illumina [3-4]"
FT miRNA 41..63
FT /accession="MIMAT0017001"
FT /product="mmu-miR-201-3p"
FT /evidence=experimental
FT /experiment="Illumina [4]"
XX
SQ Sequence 66 BP; 18 A; 11 C; 12 G; 0 T; 25 other;
uaccuuacuc aguaaggcau uguucuucua uauuaauaaa ugaacagugc cuuucugugu 60
agggua 66
//
ID mmu-mir-202 standard; RNA; MMU; 72 BP.
XX
AC MI0000245;
XX
DE Mus musculus miR-202 stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 16766679.
RA Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N,
RA Imai H;
RT "Identification and characterization of two novel classes of small RNAs in
RT the mouse germline: retrotransposon-derived siRNAs in oocytes and germline
RT small RNAs in testes";
RL Genes Dev. 20:1732-1743(2006).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [5]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676877; Mir202.
DR ENTREZGENE; 387198; Mir202.
XX
FH Key Location/Qualifiers
FH
FT miRNA 9..29
FT /accession="MIMAT0004546"
FT /product="mmu-miR-202-5p"
FT /evidence=experimental
FT /experiment="cloned [3], Illumina [4-5]"
FT miRNA 45..66
FT /accession="MIMAT0000235"
FT /product="mmu-miR-202-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Illumina [4-5]"
XX
SQ Sequence 72 BP; 16 A; 12 C; 19 G; 0 T; 25 other;
guuccuuuuu ccuaugcaua uacuucuuug uggaucuggu cuaaagaggu auagcgcaug 60
ggaagaugga gc 72
//
ID mmu-mir-203 standard; RNA; MMU; 76 BP.
XX
AC MI0000246;
XX
DE Mus musculus miR-203 stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676878; Mir203.
DR ENTREZGENE; 387199; Mir203.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [2]. The 5' end of the miRNA may be
CC offset with respect to previous annotations.
XX
FH Key Location/Qualifiers
FH
FT miRNA 10..31
FT /accession="MIMAT0004547"
FT /product="mmu-miR-203-5p"
FT /evidence=experimental
FT /experiment="cloned [2], Illumina [3-4]"
FT miRNA 48..69
FT /accession="MIMAT0000236"
FT /product="mmu-miR-203-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Illumina [3-4]"
XX
SQ Sequence 76 BP; 18 A; 18 C; 19 G; 0 T; 21 other;
gccuggucca gugguucuug acaguucaac aguucuguag cacaauugug aaauguuuag 60
gaccacuaga cccggc 76
//
ID mmu-mir-204 standard; RNA; MMU; 68 BP.
XX
AC MI0000247;
XX
DE Mus musculus miR-204 stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 16766679.
RA Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N,
RA Imai H;
RT "Identification and characterization of two novel classes of small RNAs in
RT the mouse germline: retrotransposon-derived siRNAs in oocytes and germline
RT small RNAs in testes";
RL Genes Dev. 20:1732-1743(2006).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [5]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676879; Mir204.
DR ENTREZGENE; 387200; Mir204.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..27
FT /accession="MIMAT0000237"
FT /product="mmu-miR-204-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Illumina [4-5]"
FT miRNA 45..65
FT /accession="MIMAT0017002"
FT /product="mmu-miR-204-3p"
FT /evidence=experimental
FT /experiment="Illumina [5]"
XX
SQ Sequence 68 BP; 18 A; 13 C; 20 G; 0 T; 17 other;
uggacuuccc uuugucaucc uaugccugag aauauaugaa ggaggcuggg aaggcaaagg 60
gacguuca 68
//
ID mmu-mir-205 standard; RNA; MMU; 68 BP.
XX
AC MI0000248;
XX
DE Mus musculus miR-205 stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676880; Mir205.
DR ENTREZGENE; 387201; Mir205.
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..28
FT /accession="MIMAT0000238"
FT /product="mmu-miR-205-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Illumina [3-4]"
FT miRNA 43..64
FT /accession="MIMAT0017003"
FT /product="mmu-miR-205-3p"
FT /evidence=experimental
FT /experiment="Illumina [4]"
XX
SQ Sequence 68 BP; 14 A; 18 C; 16 G; 0 T; 20 other;
cucuuguccu ucauuccacc ggagucuguc uuaugccaac cagauuucag uggagugaag 60
cucaggag 68
//
ID mmu-mir-206 standard; RNA; MMU; 73 BP.
XX
AC MI0000249;
XX
DE Mus musculus miR-206 stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676881; Mir206.
DR ENTREZGENE; 387202; Mir206.
XX
FH Key Location/Qualifiers
FH
FT miRNA 8..30
FT /accession="MIMAT0017004"
FT /product="mmu-miR-206-5p"
FT /evidence=experimental
FT /experiment="Illumina [4]"
FT miRNA 46..67
FT /accession="MIMAT0000239"
FT /product="mmu-miR-206-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Illumina [3-4]"
XX
SQ Sequence 73 BP; 18 A; 14 C; 17 G; 0 T; 24 other;
ccaggccaca ugcuucuuua uauccucaua gauaucucag cacuauggaa uguaaggaag 60
ugugugguuu ugg 73
//
ID mmu-mir-207 standard; RNA; MMU; 79 BP.
XX
AC MI0000250;
XX
DE Mus musculus miR-207 stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
DR MGI; 2676882; Mir207.
DR ENTREZGENE; 387203; Mir207.
XX
FH Key Location/Qualifiers
FH
FT miRNA 52..74
FT /accession="MIMAT0000240"
FT /product="mmu-miR-207"
FT /evidence=experimental
FT /experiment="cloned [1-2], Illumina [3]"
XX
SQ Sequence 79 BP; 7 A; 23 C; 32 G; 0 T; 17 other;
aaggcagggg ugaggggcug cgggaggagc cgggcggagg cugcggcuug cgcuucuccu 60
ggcucuccuc ccucucuuu 79
//
ID hsa-mir-208a standard; RNA; HSA; 71 BP.
XX
AC MI0000251;
XX
DE Homo sapiens miR-208a stem-loop
XX
RN [1]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [2]
RX PUBMED; 23034410.
RA Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H,
RA Khaitovich P, Kaessmann H;
RT "Birth and expression evolution of mammalian microRNA genes";
RL Genome Res. 23:34-45(2013).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-208; hsa-miR-208.
DR HGNC; 31585; MIR208A.
DR ENTREZGENE; 406990; MIR208A.
XX
FH Key Location/Qualifiers
FH
FT miRNA 9..30
FT /accession="MIMAT0026474"
FT /product="hsa-miR-208a-5p"
FT /evidence=experimental
FT /experiment="Illumina [2]"
FT miRNA 44..65
FT /accession="MIMAT0000241"
FT /product="hsa-miR-208a-3p"
FT /evidence=experimental
FT /experiment="Illumina [2]"
FT /similarity="MI0000555"
XX
SQ Sequence 71 BP; 17 A; 15 C; 21 G; 0 T; 18 other;
ugacgggcga gcuuuuggcc cggguuauac cugaugcuca cguauaagac gagcaaaaag 60
cuuguugguc a 71
//
ID hsa-mir-129-1 standard; RNA; HSA; 72 BP.
XX
AC MI0000252;
XX
DE Homo sapiens miR-129-1 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-129; hsa-miR-129.
DR HGNC; 31512; MIR129-1.
DR ENTREZGENE; 406917; MIR129-1.
XX
CC This miRNA sequence was predicted based on homology to a verified miRNA
CC cloned from mouse cerebellum [1]. Expression of this miRNA was
CC subsequently verified in a human osteoblast sarcoma cell line [2].
CC Reference [2] named the human/mouse conserved sequence miR-129b, but
CC subsequent genome searches suggest that the same mature sequence may be
CC expressed from two predicted hairpin precursors in both human (this entry
CC and MIR:MI0000473) and mouse (MIR:MI0000222 and MIR:MI0000585). Landgraf
CC et al. show that the 5' product of mir-129-1 (this entry) is the
CC predominant one, whereas both 5' and 3' products are significantly
CC expressed from mir-129-2 (MIR:MI0000585) [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 5..25
FT /accession="MIMAT0000242"
FT /product="hsa-miR-129-5p"
FT /evidence=experimental
FT /experiment="cloned [2-3]"
FT miRNA 49..70
FT /accession="MIMAT0004548"
FT /product="hsa-miR-129-1-3p"
FT /evidence=experimental
FT /experiment="cloned [3]"
XX
SQ Sequence 72 BP; 15 A; 19 C; 16 G; 0 T; 22 other;
ggaucuuuuu gcggucuggg cuugcuguuc cucucaacag uagucaggaa gcccuuaccc 60
caaaaaguau cu 72
//
ID hsa-mir-148a standard; RNA; HSA; 68 BP.
XX
AC MI0000253;
XX
DE Homo sapiens miR-148a stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 15978578.
RA Fu H, Tie Y, Xu C, Zhang Z, Zhu J, Shi Y, Jiang H, Sun Z, Zheng X;
RT "Identification of human fetal liver miRNAs by a novel method";
RL FEBS Lett. 579:3849-3854(2005).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-148a; hsa-miR-148a.
DR HGNC; 31535; MIR148A.
DR ENTREZGENE; 406940; MIR148A.
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..27
FT /accession="MIMAT0004549"
FT /product="hsa-miR-148a-5p"
FT /evidence=experimental
FT /experiment="cloned [3]"
FT miRNA 44..65
FT /accession="MIMAT0000243"
FT /product="hsa-miR-148a-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Northern [2]"
XX
SQ Sequence 68 BP; 20 A; 15 C; 16 G; 0 T; 17 other;
gaggcaaagu ucugagacac uccgacucug aguaugauag aagucagugc acuacagaac 60
uuugucuc 68
//
ID hsa-mir-30c-2 standard; RNA; HSA; 72 BP.
XX
AC MI0000254;
XX
DE Homo sapiens miR-30c-2 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [3]
RX PUBMED; 15634332.
RA Weber MJ;
RT "New human and mouse microRNA genes found by homology search";
RL FEBS J. 272:59-73(2005).
XX
RN [4]
RX PUBMED; 15978578.
RA Fu H, Tie Y, Xu C, Zhang Z, Zhu J, Shi Y, Jiang H, Sun Z, Zheng X;
RT "Identification of human fetal liver miRNAs by a novel method";
RL FEBS Lett. 579:3849-3854(2005).
XX
RN [5]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [6]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-30c; hsa-miR-30c.
DR HGNC; 31627; MIR30C2.
DR ENTREZGENE; 407032; MIR30C2.
XX
CC miR-30c was cloned from mouse heart and brain tissues by Lagos-Quintana et
CC al. [1]. Two human hairpin precursor sequences are predicted based on
CC homology with the mouse sequences, on chromosomes 1 (MIR:MI0000736) and 6
CC (MIR:MI0000254) [3]. Expression of miR-30c was later independently
CC verified in human HL-60 leukemia cells [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..29
FT /accession="MIMAT0000244"
FT /product="hsa-miR-30c-5p"
FT /evidence=experimental
FT /experiment="cloned [2,4-6]"
FT /similarity="MI0000548"
FT miRNA 47..68
FT /accession="MIMAT0004550"
FT /product="hsa-miR-30c-2-3p"
FT /evidence=experimental
FT /experiment="cloned [5]"
XX
SQ Sequence 72 BP; 22 A; 14 C; 16 G; 0 T; 20 other;
agauacugua aacauccuac acucucagcu guggaaagua agaaagcugg gagaaggcug 60
uuuacucuuu cu 72
//
ID hsa-mir-30d standard; RNA; HSA; 70 BP.
XX
AC MI0000255;
XX
DE Homo sapiens miR-30d stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
RN [4]
RX PUBMED; 17989717.
RA Marton S, Garcia MR, Robello C, Persson H, Trajtenberg F, Pritsch O,
RA Rovira C, Naya H, Dighiero G, Cayota A;
RT "Small RNAs analysis in CLL reveals a deregulation of miRNA expression and
RT novel miRNA candidates of putative relevance in CLL pathogenesis";
RL Leukemia. 22:330-338(2008).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-30d; hsa-miR-30d.
DR HGNC; 31628; MIR30D.
DR ENTREZGENE; 407033; MIR30D.
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..27
FT /accession="MIMAT0000245"
FT /product="hsa-miR-30d-5p"
FT /evidence=experimental
FT /experiment="cloned [2-4]"
FT /similarity="MI0000549"
FT miRNA 46..67
FT /accession="MIMAT0004551"
FT /product="hsa-miR-30d-3p"
FT /evidence=experimental
FT /experiment="cloned [2]"
XX
SQ Sequence 70 BP; 18 A; 16 C; 16 G; 0 T; 20 other;
guuguuguaa acauccccga cuggaagcug uaagacacag cuaagcuuuc agucagaugu 60
uugcugcuac 70
//
ID mmu-mir-122 standard; RNA; MMU; 66 BP.
XX
AC MI0000256;
XX
DE Mus musculus miR-122 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676805; Mirn122a.
DR ENTREZGENE; 387231; Mir122a.
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..27
FT /accession="MIMAT0000246"
FT /product="mmu-miR-122-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Illumina [3-4]"
FT miRNA 41..62
FT /accession="MIMAT0017005"
FT /product="mmu-miR-122-3p"
FT /evidence=experimental
FT /experiment="Illumina [4]"
XX
SQ Sequence 66 BP; 20 A; 14 C; 14 G; 0 T; 18 other;
agcuguggag ugugacaaug guguuugugu ccaaaccauc aaacgccauu aucacacuaa 60
auagcu 66
//
ID mmu-mir-143 standard; RNA; MMU; 63 BP.
XX
AC MI0000257;
XX
DE Mus musculus miR-143 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [3]
RX PUBMED; 16766679.
RA Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N,
RA Imai H;
RT "Identification and characterization of two novel classes of small RNAs in
RT the mouse germline: retrotransposon-derived siRNAs in oocytes and germline
RT small RNAs in testes";
RL Genes Dev. 20:1732-1743(2006).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [6]
RX PUBMED; 20668074.
RA Zhu JY, Strehle M, Frohn A, Kremmer E, Hofig KP, Meister G, Adler H;
RT "Identification and analysis of expression of novel microRNAs of murine
RT gammaherpesvirus 68";
RL J Virol. 84:10266-10275(2010).
XX
RN [7]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 2676828; Mir143.
DR ENTREZGENE; 387161; Mir143.
XX
CC Expression of this miRNA in mouse was independently verified in heart and
CC brain [1], embryonic stem cells [2] and testes [3]. The predominant miRNA
CC cloned by Langraf et al. has a 3' terminal U residue, which is
CC incompatible with the genome sequence [4].
XX
FH Key Location/Qualifiers
FH
FT miRNA 6..26
FT /accession="MIMAT0017006"
FT /product="mmu-miR-143-5p"
FT /evidence=experimental
FT /experiment="454 [6], Illumina [7]"
FT miRNA 40..60
FT /accession="MIMAT0000247"
FT /product="mmu-miR-143-3p"
FT /evidence=experimental
FT /experiment="cloned [1-4], Illumina [5,7]"
XX
SQ Sequence 63 BP; 12 A; 13 C; 22 G; 0 T; 16 other;
ccugaggugc agugcugcau cucuggucag uugggagucu gagaugaagc acuguagcuc 60
agg 63
//
ID mmu-mir-30e standard; RNA; MMU; 92 BP.
XX
AC MI0000259;
XX
DE Mus musculus miR-30e stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [3]
RX PUBMED; 15538371.
RA Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer
RA S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M;
RT "A pancreatic islet-specific microRNA regulates insulin secretion";
RL Nature. 432:226-230(2004).
XX
RN [4]
RX PUBMED; 16766679.
RA Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N,
RA Imai H;
RT "Identification and characterization of two novel classes of small RNAs in
RT the mouse germline: retrotransposon-derived siRNAs in oocytes and germline
RT small RNAs in testes";
RL Genes Dev. 20:1732-1743(2006).
XX
RN [5]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [6]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [7]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 3619329; Mir30e.
DR ENTREZGENE; 723836; Mir30e.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [5].
XX
FH Key Location/Qualifiers
FH
FT miRNA 17..38
FT /accession="MIMAT0000248"
FT /product="mmu-miR-30e-5p"
FT /evidence=experimental
FT /experiment="cloned [2,4-5], Illumina [6-7]"
FT miRNA 59..80
FT /accession="MIMAT0000249"
FT /product="mmu-miR-30e-3p"
FT /evidence=experimental
FT /experiment="cloned [3,5], Illumina [6-7]"
XX
SQ Sequence 92 BP; 20 A; 18 C; 29 G; 0 T; 25 other;
gggcagucuu ugcuacugua aacauccuug acuggaagcu guaagguguu gagaggagcu 60
uucagucgga uguuuacagc ggcaggcugc ca 92
//
ID hsa-mir-139 standard; RNA; HSA; 68 BP.
XX
AC MI0000261;
XX
DE Homo sapiens miR-139 stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-139; hsa-miR-139.
DR HGNC; 31526; MIR139.
DR ENTREZGENE; 406931; MIR139.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..29
FT /accession="MIMAT0000250"
FT /product="hsa-miR-139-5p"
FT /evidence=experimental
FT /experiment="cloned [2]"
FT /similarity="MI0000693"
FT miRNA 43..65
FT /accession="MIMAT0004552"
FT /product="hsa-miR-139-3p"
FT /evidence=experimental
FT /experiment="cloned [2]"
XX
SQ Sequence 68 BP; 11 A; 16 C; 24 G; 0 T; 17 other;
guguauucua cagugcacgu gucuccagug uggcucggag gcuggagacg cggcccuguu 60
ggaguaac 68
//
ID hsa-mir-147a standard; RNA; HSA; 72 BP.
XX
AC MI0000262;
XX
DE Homo sapiens miR-147a stem-loop
XX
RN [1]
RX PUBMED; 12007417.
RA Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T;
RT "Identification of tissue-specific microRNAs from mouse";
RL Curr Biol. 12:735-739(2002).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-147; hsa-miR-147.
DR HGNC; 31534; MIR147.
DR ENTREZGENE; 406939; MIR147.
XX
CC Lagos-Quintana et al. cloned miR-147 from mouse spleen tissue [1], but the
CC sequence is not present in the mouse genome assembly (NCBI32). The human
CC genome sequence contains a predicted precursor hairpin for miR-147 shown
CC in [1] (supplementary information) and represented here. The expression
CC of miR-147 has not been verified in human.
XX
FH Key Location/Qualifiers
FH
FT miRNA 47..66
FT /accession="MIMAT0000251"
FT /product="hsa-miR-147a"
FT /evidence=not_experimental
XX
SQ Sequence 72 BP; 24 A; 16 C; 14 G; 0 T; 18 other;
aaucuaaaga caacauuucu gcacacacac cagacuaugg aagccagugu guggaaaugc 60
uucugcuaga uu 72
//
ID hsa-mir-7-1 standard; RNA; HSA; 110 BP.
XX
AC MI0000263;
XX
DE Homo sapiens miR-7-1 stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR RFAM; RF00053; mir-7.
DR TARGETS:PICTAR-VERT; hsa-miR-7; hsa-miR-7.
DR HGNC; 31638; MIR7-1.
DR ENTREZGENE; 407043; MIR7-1.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised miR
CC has been validated in zebrafish, and the 5' end mapped by PCR. Landgraf
CC et al. confirm expression in human [2]. The mature sequence shown here
CC represents the most commonly cloned form from large-scale cloning studies
CC [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 24..47
FT /accession="MIMAT0000252"
FT /product="hsa-miR-7-5p"
FT /evidence=experimental
FT /experiment="cloned [2-3]"
FT /similarity="MI0001360"
FT miRNA 66..87
FT /accession="MIMAT0004553"
FT /product="hsa-miR-7-1-3p"
FT /evidence=experimental
FT /experiment="cloned [2]"
XX
SQ Sequence 110 BP; 29 A; 21 C; 25 G; 0 T; 35 other;
uuggauguug gccuaguucu guguggaaga cuagugauuu uguuguuuuu agauaacuaa 60
aucgacaaca aaucacaguc ugccauaugg cacaggccau gccucuacag 110
//
ID hsa-mir-7-2 standard; RNA; HSA; 110 BP.
XX
AC MI0000264;
XX
DE Homo sapiens miR-7-2 stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR RFAM; RF00053; mir-7.
DR TARGETS:PICTAR-VERT; hsa-miR-7; hsa-miR-7.
DR HGNC; 31639; MIR7-2.
DR ENTREZGENE; 407044; MIR7-2.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised miR
CC has been validated in zebrafish, and the 5' end mapped by PCR. Landgraf
CC et al. confirm expression in human [2]. The mature sequence shown here
CC represents the most commonly cloned form from large-scale cloning studies
CC [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 32..55
FT /accession="MIMAT0000252"
FT /product="hsa-miR-7-5p"
FT /evidence=experimental
FT /experiment="cloned [2-3]"
FT /similarity="MI0001361"
FT miRNA 72..93
FT /accession="MIMAT0004554"
FT /product="hsa-miR-7-2-3p"
FT /evidence=experimental
FT /experiment="cloned [2]"
XX
SQ Sequence 110 BP; 26 A; 30 C; 26 G; 0 T; 28 other;
cuggauacag aguggaccgg cuggccccau cuggaagacu agugauuuug uuguugucuu 60
acugcgcuca acaacaaauc ccagucuacc uaauggugcc agccaucgca 110
//
ID hsa-mir-7-3 standard; RNA; HSA; 110 BP.
XX
AC MI0000265;
XX
DE Homo sapiens miR-7-3 stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR RFAM; RF00053; mir-7.
DR TARGETS:PICTAR-VERT; hsa-miR-7; hsa-miR-7.
DR HGNC; 31640; MIR7-3.
DR ENTREZGENE; 407045; MIR7-3.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised miR
CC has been validated in zebrafish, and the 5' end mapped by PCR. Expression
CC in human was later verified by cloning [1,2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 31..54
FT /accession="MIMAT0000252"
FT /product="hsa-miR-7-5p"
FT /evidence=experimental
FT /experiment="cloned [2-3]"
FT /similarity="MI0001362"
XX
SQ Sequence 110 BP; 25 A; 24 C; 30 G; 0 T; 31 other;
agauuagagu ggcugugguc uagugcugug uggaagacua gugauuuugu uguucugaug 60
uacuacgaca acaagucaca gccggccuca uagcgcagac ucccuucgac 110
//
ID hsa-mir-10a standard; RNA; HSA; 110 BP.
XX
AC MI0000266;
XX
DE Homo sapiens miR-10a stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR RFAM; RF00104; mir-10.
DR TARGETS:PICTAR-VERT; hsa-miR-10a; hsa-miR-10a.
DR HGNC; 31497; MIR10A.
DR ENTREZGENE; 406902; MIR10A.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised miR
CC has been validated in zebrafish, and the ends mapped by cloning. Mature
CC products were later verified in human [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 22..44
FT /accession="MIMAT0000253"
FT /product="hsa-miR-10a-5p"
FT /evidence=experimental
FT /experiment="cloned [2-3]"
FT /similarity="MI0001363"
FT miRNA 63..84
FT /accession="MIMAT0004555"
FT /product="hsa-miR-10a-3p"
FT /evidence=experimental
FT /experiment="cloned [2]"
XX
SQ Sequence 110 BP; 28 A; 20 C; 23 G; 0 T; 39 other;
gaucugucug ucuucuguau auacccugua gauccgaauu uguguaagga auuuuguggu 60
cacaaauucg uaucuagggg aauauguagu ugacauaaac acuccgcucu 110
//
ID hsa-mir-10b standard; RNA; HSA; 110 BP.
XX
AC MI0000267;
XX
DE Homo sapiens miR-10b stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 14573789.
RA Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ;
RT "Reduced accumulation of specific microRNAs in colorectal neoplasia";
RL Mol Cancer Res. 1:882-891(2003).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR RFAM; RF00104; mir-10.
DR TARGETS:PICTAR-VERT; hsa-miR-10b; hsa-miR-10b.
DR HGNC; 31498; MIR10B.
DR ENTREZGENE; 406903; MIR10B.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised miR
CC has been validated in zebrafish, and the ends mapped by cloning. Michael
CC et al. subsequently verified expression of miR-10b in human [2]. The
CC mature sequence shown here represents the most commonly cloned form from
CC large-scale cloning studies [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 27..49
FT /accession="MIMAT0000254"
FT /product="hsa-miR-10b-5p"
FT /evidence=experimental
FT /experiment="cloned [2-4]"
FT miRNA 66..87
FT /accession="MIMAT0004556"
FT /product="hsa-miR-10b-3p"
FT /evidence=experimental
FT /experiment="cloned [3]"
XX
SQ Sequence 110 BP; 32 A; 19 C; 25 G; 0 T; 34 other;
ccagagguug uaacguuguc uauauauacc cuguagaacc gaauuugugu gguauccgua 60
uagucacaga uucgauucua ggggaauaua uggucgaugc aaaaacuuca 110
//
ID hsa-mir-34a standard; RNA; HSA; 110 BP.
XX
AC MI0000268;
XX
DE Homo sapiens miR-34a stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
RC Erratum RNA 9:631-632(2003).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-34a; hsa-miR-34a.
DR HGNC; 31635; MIR34A.
DR ENTREZGENE; 407040; MIR34A.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised miR
CC has been validated in zebrafish, and the ends mapped by cloning. Dostie
CC et al. independently cloned this sequence in human but misnamed the
CC sequence miR-172 (the sequence is unrelated to MIR172 from Arabidopsis)
CC [2]. The sequence maps to human chromosome 1. Human miR-34a was
CC previously named miR-34 here and in [1], but is renamed to clarify
CC homology with the alternatively named mouse sequence (MIR:MI0000584). The
CC mature sequence shown here represents the most commonly cloned form from
CC large-scale cloning studies [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 22..43
FT /accession="MIMAT0000255"
FT /product="hsa-miR-34a-5p"
FT /evidence=experimental
FT /experiment="cloned [2-4]"
FT miRNA 64..85
FT /accession="MIMAT0004557"
FT /product="hsa-miR-34a-3p"
FT /evidence=experimental
FT /experiment="cloned [3]"
XX
SQ Sequence 110 BP; 23 A; 21 C; 35 G; 0 T; 31 other;
ggccagcugu gaguguuucu uuggcagugu cuuagcuggu uguugugagc aauaguaagg 60
aagcaaucag caaguauacu gcccuagaag ugcugcacgu uguggggccc 110
//
ID hsa-mir-181a-2 standard; RNA; HSA; 110 BP.
XX
AC MI0000269;
XX
DE Homo sapiens miR-181a-2 stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
XX
RN [3]
RX PUBMED; 15634332.
RA Weber MJ;
RT "New human and mouse microRNA genes found by homology search";
RL FEBS J. 272:59-73(2005).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
RN [6]
RX PUBMED; 17989717.
RA Marton S, Garcia MR, Robello C, Persson H, Trajtenberg F, Pritsch O,
RA Rovira C, Naya H, Dighiero G, Cayota A;
RT "Small RNAs analysis in CLL reveals a deregulation of miRNA expression and
RT novel miRNA candidates of putative relevance in CLL pathogenesis";
RL Leukemia. 22:330-338(2008).
XX
DR RFAM; RF00076; mir-181.
DR TARGETS:PICTAR-VERT; hsa-mir-181a-2; hsa-mir-181a-2.
DR HGNC; 31549; MIR181A2.
DR ENTREZGENE; 406954; MIR181A2.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised miR
CC has been validated in zebrafish, and the ends mapped by cloning. Landgraf
CC et al. and Lui et al. later verify expression in human [4-5].
XX
FH Key Location/Qualifiers
FH
FT miRNA 39..61
FT /accession="MIMAT0000256"
FT /product="hsa-miR-181a-5p"
FT /evidence=experimental
FT /experiment="cloned [2,4-6]"
FT miRNA 77..98
FT /accession="MIMAT0004558"
FT /product="hsa-miR-181a-2-3p"
FT /evidence=experimental
FT /experiment="cloned [4]"
XX
SQ Sequence 110 BP; 29 A; 25 C; 30 G; 0 T; 26 other;
agaagggcua ucaggccagc cuucagagga cuccaaggaa cauucaacgc ugucggugag 60
uuugggauuu gaaaaaacca cugaccguug acuguaccuu gggguccuua 110
//
ID hsa-mir-181b-1 standard; RNA; HSA; 110 BP.
XX
AC MI0000270;
XX
DE Homo sapiens miR-181b-1 stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 15634332.
RA Weber MJ;
RT "New human and mouse microRNA genes found by homology search";
RL FEBS J. 272:59-73(2005).
XX
RN [3]
RX PUBMED; 15800047.
RA Cai X, Lu S, Zhang Z, Gonzalez CM, Damania B, Cullen BR;
RT "Kaposi's sarcoma-associated herpesvirus expresses an array of viral
RT microRNAs in latently infected cells";
RL Proc Natl Acad Sci U S A. 102:5570-5575(2005).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR RFAM; RF00076; mir-181.
DR TARGETS:PICTAR-VERT; hsa-miR-181b; hsa-miR-181b.
DR HGNC; 31550; MIR181B1.
DR ENTREZGENE; 406955; MIR181B1.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised miR
CC has been validated in zebrafish, and the ends mapped by cloning. Its
CC expression was later verified in human BC-1 cells [3]. There are two
CC predicted hairpin precursor sequences in the human genome; mir-181b-1
CC (MIR:MI0000270) is found on chromosome 1 [1], and mir-181b-2
CC (MIR:MI0000683) on chromosome 9 [2]. The mature sequence shown here
CC represents the most commonly cloned form from large-scale cloning studies
CC [4].
XX
FH Key Location/Qualifiers
FH
FT miRNA 36..58
FT /accession="MIMAT0000257"
FT /product="hsa-miR-181b-5p"
FT /evidence=experimental
FT /experiment="cloned [3-5]"
FT /similarity="MI0001366"
FT miRNA 76..96
FT /accession="MIMAT0022692"
FT /product="hsa-miR-181b-3p"
FT /evidence=not_experimental
XX
SQ Sequence 110 BP; 29 A; 23 C; 26 G; 0 T; 32 other;
ccugugcaga gauuauuuuu uaaaagguca caaucaacau ucauugcugu cgguggguug 60
aacugugugg acaagcucac ugaacaauga augcaacugu ggccccgcuu 110
//
ID hsa-mir-181c standard; RNA; HSA; 110 BP.
XX
AC MI0000271;
XX
DE Homo sapiens miR-181c stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
DR RFAM; RF00076; mir-181.
DR TARGETS:PICTAR-VERT; hsa-miR-181c; hsa-miR-181c.
DR HGNC; 31552; MIR181C.
DR ENTREZGENE; 406957; MIR181C.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised miR
CC has been validated in zebrafish, and the ends mapped by cloning. Landgraf
CC et al. confirm the expression of miR-181c in human [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 27..48
FT /accession="MIMAT0000258"
FT /product="hsa-miR-181c-5p"
FT /evidence=experimental
FT /experiment="cloned [2]"
FT /similarity="MI0001380"
FT miRNA 65..86
FT /accession="MIMAT0004559"
FT /product="hsa-miR-181c-3p"
FT /evidence=experimental
FT /experiment="cloned [2]"
XX
SQ Sequence 110 BP; 25 A; 26 C; 34 G; 0 T; 25 other;
cggaaaauuu gccaaggguu ugggggaaca uucaaccugu cggugaguuu gggcagcuca 60
ggcaaaccau cgaccguuga guggacccug aggccuggaa uugccauccu 110
//
ID hsa-mir-182 standard; RNA; HSA; 110 BP.
XX
AC MI0000272;
XX
DE Homo sapiens miR-182 stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-182; hsa-miR-182.
DR TARGETS:PICTAR-VERT; hsa-miR-182*; hsa-miR-182*.
DR HGNC; 31553; MIR182.
DR ENTREZGENE; 406958; MIR182.
XX
FH Key Location/Qualifiers
FH
FT miRNA 23..46
FT /accession="MIMAT0000259"
FT /product="hsa-miR-182-5p"
FT /evidence=experimental
FT /experiment="cloned [2-3]"
FT /similarity="MI0001368"
FT miRNA 67..87
FT /accession="MIMAT0000260"
FT /product="hsa-miR-182-3p"
FT /evidence=not_experimental
FT /similarity="MI0001368"
XX
SQ Sequence 110 BP; 22 A; 30 C; 33 G; 0 T; 25 other;
gagcugcuug ccuccccccg uuuuuggcaa ugguagaacu cacacuggug agguaacagg 60
auccgguggu ucuagacuug ccaacuaugg ggcgaggacu cagccggcac 110
//
ID hsa-mir-183 standard; RNA; HSA; 110 BP.
XX
AC MI0000273;
XX
DE Homo sapiens miR-183 stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-183; hsa-miR-183.
DR HGNC; 31554; MIR183.
DR ENTREZGENE; 406959; MIR183.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised miR
CC has been validated in zebrafish, and the 5' end mapped by PCR. Expression
CC was later confirmed in human [2,3]. The mature sequence shown here
CC represents the most commonly cloned form from large-scale cloning studies
CC [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 27..48
FT /accession="MIMAT0000261"
FT /product="hsa-miR-183-5p"
FT /evidence=experimental
FT /experiment="cloned [2-4]"
FT miRNA 66..87
FT /accession="MIMAT0004560"
FT /product="hsa-miR-183-3p"
FT /evidence=experimental
FT /experiment="cloned [3]"
XX
SQ Sequence 110 BP; 32 A; 25 C; 29 G; 0 T; 24 other;
ccgcagagug ugacuccugu ucuguguaug gcacugguag aauucacugu gaacagucuc 60
agucagugaa uuaccgaagg gccauaaaca gagcagagac agauccacga 110
//
ID hsa-mir-187 standard; RNA; HSA; 109 BP.
XX
AC MI0000274;
XX
DE Homo sapiens miR-187 stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-187; hsa-miR-187.
DR HGNC; 31558; MIR187.
DR ENTREZGENE; 406963; MIR187.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised miR
CC has been validated in zebrafish, and the 5' end mapped by PCR. Landgraf
CC et al. confirm expression in human [2]. The mature sequence shown here
CC represents the most commonly cloned form from large-scale cloning studies
CC [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 35..56
FT /accession="MIMAT0004561"
FT /product="hsa-miR-187-5p"
FT /evidence=experimental
FT /experiment="cloned [2]"
FT miRNA 71..92
FT /accession="MIMAT0000262"
FT /product="hsa-miR-187-3p"
FT /evidence=experimental
FT /experiment="cloned [2]"
FT /similarity="MI0001370"
XX
SQ Sequence 109 BP; 19 A; 35 C; 36 G; 0 T; 19 other;
ggucgggcuc accaugacac agugugagac cucgggcuac aacacaggac ccgggcgcug 60
cucugacccc ucgugucuug uguugcagcc ggagggacgc agguccgca 109
//
ID hsa-mir-196a-2 standard; RNA; HSA; 110 BP.
XX
AC MI0000279;
XX
DE Homo sapiens miR-196a-2 stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 15105502.
RA Yekta S, Shih IH, Bartel DP;
RT "MicroRNA-directed cleavage of HOXB8 mRNA";
RL Science. 304:594-596(2004).
XX
RN [3]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-196a; hsa-miR-196a.
DR HGNC; 31568; MIR196A2.
DR ENTREZGENE; 406973; MIR196A2.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised miR
CC has been validated in zebrafish, and the ends mapped by cloning. miR-196a
CC was later validated in human [3,4]. Yekta et al. report that miR-196
CC miRNAs are expressed from HOX gene clusters in mammals, and that HOX genes
CC in these clusters are targets of miR-196. Indeed, HOXB8 mRNA was shown to
CC be a natural target for miR-196-directed cleavage through a perfectly
CC complementary miR-target site. Other HOX genes have imperfect miR-196
CC complementary sites indicative of regulation by translational repression
CC [2]. The mature sequence shown here represents the most commonly cloned
CC form from large-scale cloning studies [4].
XX
FH Key Location/Qualifiers
FH
FT miRNA 25..46
FT /accession="MIMAT0000226"
FT /product="hsa-miR-196a-5p"
FT /evidence=experimental
FT /experiment="cloned [3-5]"
FT miRNA 62..83
FT /accession="MIMAT0004562"
FT /product="hsa-miR-196a-3p"
FT /evidence=experimental
FT /experiment="cloned [4]"
XX
SQ Sequence 110 BP; 21 A; 21 C; 32 G; 0 T; 36 other;
ugcucgcuca gcugaucugu ggcuuaggua guuucauguu guugggauug aguuuugaac 60
ucggcaacaa gaaacugccu gaguuacauc agucgguuuu cgucgagggc 110
//
ID hsa-mir-199a-2 standard; RNA; HSA; 110 BP.
XX
AC MI0000281;
XX
DE Homo sapiens miR-199a-2 stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 12554859.
RA Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T;
RT "New microRNAs from mouse and human";
RL RNA. 9:175-179(2003).
XX
RN [3]
RX PUBMED; 15978578.
RA Fu H, Tie Y, Xu C, Zhang Z, Zhu J, Shi Y, Jiang H, Sun Z, Zheng X;
RT "Identification of human fetal liver miRNAs by a novel method";
RL FEBS Lett. 579:3849-3854(2005).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 20158877.
RA Koh W, Sheng CT, Tan B, Lee QY, Kuznetsov V, Kiang LS, Tanavde V;
RT "Analysis of deep sequencing microRNA expression profile from human
RT embryonic stem cells derived mesenchymal stem cells reveals possible role
RT of let-7 microRNA family in downstream targeting of hepatic nuclear factor
RT 4 alpha";
RL BMC Genomics. 11 Suppl 1:S6(2010).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-199a; hsa-miR-199a.
DR TARGETS:PICTAR-VERT; hsa-miR-199a*; hsa-miR-199a*.
DR HGNC; 31572; MIR199A2.
DR ENTREZGENE; 406977; MIR199A2.
XX
CC Lagos-Quintana et al. [1] cloned miR-199 from human osteoblast sarcoma
CC cells. They also reported identification of a miRNA from the opposite arm
CC in mouse cells. This sequence was named miR-199-s and the sequence from
CC the 3' arm of the homologous mouse precursor miR-199-as. Lim et al. [2]
CC independently predicted this miRNA computationally using conservation with
CC mouse and Fugu rubripes sequences [2]. Expression of the miR excised from
CC the 5' arm was validated in zebrafish, and the ends mapped by cloning. The
CC excised miR sequences are renamed miR-199a (to avoid confusion with the
CC subsequently identified miR-199b (MIR:MI0000282)) and miR-199a* (from the
CC 3' arm) here. The two putative hairpin precursors in human map to
CC chromosome 19 (mir-199a-1, MIR:MI0000242) and chromosome 1 (mir-199a-2,
CC MIR:MI0000281). Landgraf et al. show that both mature products are
CC expressed, prompting the renaming to miR-199a-5p and miR-199a-3p [4].
XX
FH Key Location/Qualifiers
FH
FT miRNA 31..53
FT /accession="MIMAT0000231"
FT /product="hsa-miR-199a-5p"
FT /evidence=experimental
FT /experiment="cloned [2-4]"
FT miRNA 70..91
FT /accession="MIMAT0000232"
FT /product="hsa-miR-199a-3p"
FT /evidence=experimental
FT /experiment="cloned [4], Illumina [5]"
FT /similarity="MI0000713"
XX
SQ Sequence 110 BP; 25 A; 27 C; 32 G; 0 T; 26 other;
aggaagcuuc uggagauccu gcuccgucgc cccaguguuc agacuaccug uucaggacaa 60
ugccguugua caguagucug cacauugguu agacugggca agggagagca 110
//
ID hsa-mir-199b standard; RNA; HSA; 110 BP.
XX
AC MI0000282;
XX
DE Homo sapiens miR-199b stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 14573789.
RA Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ;
RT "Reduced accumulation of specific microRNAs in colorectal neoplasia";
RL Mol Cancer Res. 1:882-891(2003).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-199b; hsa-miR-199b.
DR HGNC; 31573; MIR199B.
DR ENTREZGENE; 406978; MIR199B.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised 5'
CC miR has been validated in zebrafish, the ends mapped by cloning [2], and
CC later verified in human [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 26..48
FT /accession="MIMAT0000263"
FT /product="hsa-miR-199b-5p"
FT /evidence=experimental
FT /experiment="cloned [2-3]"
FT miRNA 65..86
FT /accession="MIMAT0004563"
FT /product="hsa-miR-199b-3p"
FT /evidence=experimental
FT /experiment="cloned [3]"
XX
SQ Sequence 110 BP; 23 A; 31 C; 27 G; 0 T; 29 other;
ccagaggaca ccuccacucc gucuacccag uguuuagacu aucuguucag gacucccaaa 60
uuguacagua gucugcacau ugguuaggcu gggcuggguu agacccucgg 110
//
ID hsa-mir-203a standard; RNA; HSA; 110 BP.
XX
AC MI0000283;
XX
DE Homo sapiens miR-203a stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 17622355.
RA Sonkoly E, Wei T, Janson PC, Saaf A, Lundeberg L, Tengvall-Linder M,
RA Norstedt G, Alenius H, Homey B, Scheynius A, Stahle M, Pivarcsi A;
RT "MicroRNAs: novel regulators involved in the pathogenesis of psoriasis?";
RL PLoS One. 2:e610(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-203; hsa-miR-203.
DR HGNC; 31581; MIR203.
DR ENTREZGENE; 406986; MIR203.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised miR
CC has been validated in zebrafish, and the ends mapped by cloning. Landgraf
CC et al. confirm expression in human [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 27..51
FT /accession="MIMAT0031890"
FT /product="hsa-miR-203a-5p"
FT /evidence=not_experimental
FT miRNA 65..86
FT /accession="MIMAT0000264"
FT /product="hsa-miR-203a-3p"
FT /evidence=experimental
FT /experiment="cloned [2]"
FT /similarity="MI0001376"
XX
SQ Sequence 110 BP; 22 A; 26 C; 37 G; 0 T; 25 other;
guguugggga cucgcgcgcu ggguccagug guucuuaaca guucaacagu ucuguagcgc 60
aauugugaaa uguuuaggac cacuagaccc ggcgggcgcg gcgacagcga 110
//
ID hsa-mir-204 standard; RNA; HSA; 110 BP.
XX
AC MI0000284;
XX
DE Homo sapiens miR-204 stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-204; hsa-miR-204.
DR HGNC; 31582; MIR204.
DR ENTREZGENE; 406987; MIR204.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised miR
CC has been validated in zebrafish, and the ends mapped by cloning. Landgraf
CC et al. confirm expression in human [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 33..54
FT /accession="MIMAT0000265"
FT /product="hsa-miR-204-5p"
FT /evidence=experimental
FT /experiment="cloned [2]"
FT /similarity="MI0001377"
FT miRNA 72..92
FT /accession="MIMAT0022693"
FT /product="hsa-miR-204-3p"
FT /evidence=not_experimental
XX
SQ Sequence 110 BP; 25 A; 24 C; 29 G; 0 T; 32 other;
ggcuacaguc uuucuucaug ugacucgugg acuucccuuu gucauccuau gccugagaau 60
auaugaagga ggcugggaag gcaaagggac guucaauugu caucacuggc 110
//
ID hsa-mir-205 standard; RNA; HSA; 110 BP.
XX
AC MI0000285;
XX
DE Homo sapiens miR-205 stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
RN [4]
RX PUBMED; 19144710.
RA Zhu JY, Pfuhl T, Motsch N, Barth S, Nicholls J, Grasser F, Meister G;
RT "Identification of novel Epstein-Barr virus microRNA genes from
RT nasopharyngeal carcinomas";
RL J Virol. 83:3333-3341(2009).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-205; hsa-miR-205.
DR HGNC; 31583; MIR205.
DR ENTREZGENE; 406988; MIR205.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised miR
CC has been validated in zebrafish, and the ends mapped by cloning. Landgraf
CC et al. confirm expression in human [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 34..55
FT /accession="MIMAT0000266"
FT /product="hsa-miR-205-5p"
FT /evidence=experimental
FT /experiment="cloned [2-3]"
FT /similarity="MI0001378"
FT miRNA 71..91
FT /accession="MIMAT0009197"
FT /product="hsa-miR-205-3p"
FT /evidence=experimental
FT /experiment="454 [4]"
XX
SQ Sequence 110 BP; 28 A; 29 C; 24 G; 0 T; 29 other;
aaagauccuc agacaaucca ugugcuucuc uuguccuuca uuccaccgga gucugucuca 60
uacccaacca gauuucagug gagugaaguu caggaggcau ggagcugaca 110
//
ID hsa-mir-210 standard; RNA; HSA; 110 BP.
XX
AC MI0000286;
XX
DE Homo sapiens miR-210 stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 15800047.
RA Cai X, Lu S, Zhang Z, Gonzalez CM, Damania B, Cullen BR;
RT "Kaposi's sarcoma-associated herpesvirus expresses an array of viral
RT microRNAs in latently infected cells";
RL Proc Natl Acad Sci U S A. 102:5570-5575(2005).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
RN [5]
RX PUBMED; 23034410.
RA Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H,
RA Khaitovich P, Kaessmann H;
RT "Birth and expression evolution of mammalian microRNA genes";
RL Genome Res. 23:34-45(2013).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-210; hsa-miR-210.
DR HGNC; 31587; MIR210.
DR ENTREZGENE; 406992; MIR210.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised miR
CC has been validated in zebrafish, and the ends mapped by cloning. Its
CC expression was later verified in human BC-1 cells [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 28..49
FT /accession="MIMAT0026475"
FT /product="hsa-miR-210-5p"
FT /evidence=experimental
FT /experiment="Illumina [5]"
FT miRNA 66..87
FT /accession="MIMAT0000267"
FT /product="hsa-miR-210-3p"
FT /evidence=experimental
FT /experiment="cloned [2-4], Illumina [5]"
FT /similarity="MI0001379"
XX
SQ Sequence 110 BP; 16 A; 46 C; 34 G; 0 T; 14 other;
acccggcagu gccuccaggc gcagggcagc cccugcccac cgcacacugc gcugccccag 60
acccacugug cgugugacag cggcugaucu gugccugggc agcgcgaccc 110
//
ID hsa-mir-211 standard; RNA; HSA; 110 BP.
XX
AC MI0000287;
XX
DE Homo sapiens miR-211 stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-211; hsa-miR-211.
DR HGNC; 31588; MIR211.
DR ENTREZGENE; 406993; MIR211.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised miR
CC has been validated in zebrafish, and the ends mapped by cloning. The
CC sequence maps to human chromosome 15.
XX
FH Key Location/Qualifiers
FH
FT miRNA 26..47
FT /accession="MIMAT0000268"
FT /product="hsa-miR-211-5p"
FT /evidence=not_experimental
FT /similarity="MI0001377"
FT miRNA 63..83
FT /accession="MIMAT0022694"
FT /product="hsa-miR-211-3p"
FT /evidence=not_experimental
XX
SQ Sequence 110 BP; 19 A; 32 C; 33 G; 0 T; 26 other;
ucaccuggcc augugacuug ugggcuuccc uuugucaucc uucgccuagg gcucugagca 60
gggcagggac agcaaagggg ugcucaguug ucacuuccca cagcacggag 110
//
ID hsa-mir-212 standard; RNA; HSA; 110 BP.
XX
AC MI0000288;
XX
DE Homo sapiens miR-212 stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-212; hsa-miR-212.
DR HGNC; 31589; MIR212.
DR ENTREZGENE; 406994; MIR212.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised miR
CC has been validated in zebrafish, and the 5' end mapped by PCR. The 3' end
CC was not experimentally determined. The sequence maps to human chromosome
CC 17, but its expression has not been experimentally verified in human.
XX
FH Key Location/Qualifiers
FH
FT miRNA 31..53
FT /accession="MIMAT0022695"
FT /product="hsa-miR-212-5p"
FT /evidence=not_experimental
FT miRNA 71..91
FT /accession="MIMAT0000269"
FT /product="hsa-miR-212-3p"
FT /evidence=not_experimental
FT /similarity="MI0003385"
XX
SQ Sequence 110 BP; 15 A; 50 C; 31 G; 0 T; 14 other;
cggggcaccc cgcccggaca gcgcgccggc accuuggcuc uagacugcuu acugcccggg 60
ccgcccucag uaacagucuc cagucacggc caccgacgcc uggccccgcc 110
//
ID hsa-mir-181a-1 standard; RNA; HSA; 110 BP.
XX
AC MI0000289;
XX
DE Homo sapiens miR-181a-1 stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
XX
RN [3]
RX PUBMED; 15634332.
RA Weber MJ;
RT "New human and mouse microRNA genes found by homology search";
RL FEBS J. 272:59-73(2005).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
RN [6]
RX PUBMED; 17989717.
RA Marton S, Garcia MR, Robello C, Persson H, Trajtenberg F, Pritsch O,
RA Rovira C, Naya H, Dighiero G, Cayota A;
RT "Small RNAs analysis in CLL reveals a deregulation of miRNA expression and
RT novel miRNA candidates of putative relevance in CLL pathogenesis";
RL Leukemia. 22:330-338(2008).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-181a; hsa-miR-181a.
DR HGNC; 31590; MIR181A1.
DR ENTREZGENE; 406995; MIR181A1.
XX
FH Key Location/Qualifiers
FH
FT miRNA 24..46
FT /accession="MIMAT0000256"
FT /product="hsa-miR-181a-5p"
FT /evidence=experimental
FT /experiment="cloned [2,4-6]"
FT miRNA 64..85
FT /accession="MIMAT0000270"
FT /product="hsa-miR-181a-3p"
FT /evidence=experimental
FT /experiment="cloned [4]"
FT /similarity="MI0001380"
XX
SQ Sequence 110 BP; 30 A; 24 C; 22 G; 0 T; 34 other;
ugaguuuuga gguugcuuca gugaacauuc aacgcugucg gugaguuugg aauuaaaauc 60
aaaaccaucg accguugauu guacccuaug gcuaaccauc aucuacucca 110
//
ID hsa-mir-214 standard; RNA; HSA; 110 BP.
XX
AC MI0000290;
XX
DE Homo sapiens miR-214 stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 18230126.
RA Afanasyeva EA, Hotz-Wagenblatt A, Glatting KH, Westermann F;
RT "New miRNAs cloned from neuroblastoma";
RL BMC Genomics. 9:52(2008).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-214; hsa-miR-214.
DR HGNC; 31591; MIR214.
DR ENTREZGENE; 406996; MIR214.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised miR
CC has been validated in zebrafish, and the ends mapped by cloning. Landgraf
CC et al. confirm expression in human [2]. The mature sequence shown here
CC represents the most commonly cloned form from large-scale cloning studies
CC [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 30..51
FT /accession="MIMAT0004564"
FT /product="hsa-miR-214-5p"
FT /evidence=experimental
FT /experiment="cloned [2-3], Northern [3]"
FT miRNA 71..92
FT /accession="MIMAT0000271"
FT /product="hsa-miR-214-3p"
FT /evidence=experimental
FT /experiment="cloned [2]"
FT /similarity="MI0001381"
XX
SQ Sequence 110 BP; 25 A; 34 C; 28 G; 0 T; 23 other;
ggccuggcug gacagaguug ucaugugucu gccugucuac acuugcugug cagaacaucc 60
gcucaccugu acagcaggca cagacaggca gucacaugac aacccagccu 110
//
ID hsa-mir-215 standard; RNA; HSA; 110 BP.
XX
AC MI0000291;
XX
DE Homo sapiens miR-215 stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 23034410.
RA Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H,
RA Khaitovich P, Kaessmann H;
RT "Birth and expression evolution of mammalian microRNA genes";
RL Genome Res. 23:34-45(2013).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-215; hsa-miR-215.
DR HGNC; 31592; MIR215.
DR ENTREZGENE; 406997; MIR215.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised miR
CC has been validated in zebrafish, and the 5' end mapped by PCR. Landgraf
CC et al. confirm expression in human [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 27..47
FT /accession="MIMAT0000272"
FT /product="hsa-miR-215-5p"
FT /evidence=experimental
FT /experiment="cloned [2], Illumina [3]"
FT miRNA 64..86
FT /accession="MIMAT0026476"
FT /product="hsa-miR-215-3p"
FT /evidence=experimental
FT /experiment="Illumina [3]"
XX
SQ Sequence 110 BP; 35 A; 18 C; 20 G; 0 T; 37 other;
aucauucaga aaugguauac aggaaaauga ccuaugaauu gacagacaau auagcugagu 60
uugucuguca uuucuuuagg ccaauauucu guaugacugu gcuacuucaa 110
//
ID hsa-mir-216a standard; RNA; HSA; 110 BP.
XX
AC MI0000292;
XX
DE Homo sapiens miR-216a stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 22282338.
RA Voellenkle C, Rooij Jv, Guffanti A, Brini E, Fasanaro P, Isaia E, Croft L,
RA David M, Capogrossi MC, Moles A, Felsani A, Martelli F;
RT "Deep-sequencing of endothelial cells exposed to hypoxia reveals the
RT complexity of known and novel microRNAs";
RL RNA. 18:472-484(2012).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-216; hsa-miR-216.
DR HGNC; 31593; MIR216A.
DR ENTREZGENE; 406998; MIR216A.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised miR
CC has been validated in zebrafish, and the 5' end mapped by PCR. The mature
CC sequence shown here represents the most commonly cloned form from
CC large-scale cloning studies [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 19..40
FT /accession="MIMAT0000273"
FT /product="hsa-miR-216a-5p"
FT /evidence=experimental
FT /experiment="cloned [2], SOLiD [3]"
FT /similarity="MI0001382"
FT miRNA 58..79
FT /accession="MIMAT0022844"
FT /product="hsa-miR-216a-3p"
FT /evidence=experimental
FT /experiment="SOLiD [3]"
XX
SQ Sequence 110 BP; 27 A; 26 C; 26 G; 0 T; 31 other;
gauggcugug aguuggcuua aucucagcug gcaacuguga gauguucaua caaucccuca 60
caguggucuc ugggauuaug cuaaacagag caauuuccua gcccucacga 110
//
ID hsa-mir-217 standard; RNA; HSA; 110 BP.
XX
AC MI0000293;
XX
DE Homo sapiens miR-217 stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-217; hsa-miR-217.
DR HGNC; 31594; MIR217.
DR ENTREZGENE; 406999; MIR217.
XX
FH Key Location/Qualifiers
FH
FT miRNA 35..57
FT /accession="MIMAT0000274"
FT /product="hsa-miR-217-5p"
FT /evidence=experimental
FT /experiment="cloned [2]"
FT /similarity="MI0001383"
FT miRNA 72..93
FT /accession="MIMAT0037308"
FT /product="hsa-miR-217-3p"
FT /evidence=not_experimental
XX
SQ Sequence 110 BP; 36 A; 21 C; 19 G; 0 T; 34 other;
aguauaauua uuacauaguu uuugaugucg cagauacugc aucaggaacu gauuggauaa 60
gaaucaguca ccaucaguuc cuaaugcauu gccuucagca ucuaaacaag 110
//
ID hsa-mir-218-1 standard; RNA; HSA; 110 BP.
XX
AC MI0000294;
XX
DE Homo sapiens miR-218-1 stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-218; hsa-miR-218.
DR HGNC; 31595; MIR218-1.
DR ENTREZGENE; 407000; MIR218-1.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised miR
CC has been validated in zebrafish, and the 5' end mapped by PCR. Landgraf
CC et al. later verified the expression of miR-218 in human [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 25..45
FT /accession="MIMAT0000275"
FT /product="hsa-miR-218-5p"
FT /evidence=experimental
FT /experiment="cloned [2-3]"
FT /similarity="MI0000958"
FT miRNA 68..89
FT /accession="MIMAT0004565"
FT /product="hsa-miR-218-1-3p"
FT /evidence=experimental
FT /experiment="cloned [2]"
XX
SQ Sequence 110 BP; 28 A; 21 C; 28 G; 0 T; 33 other;
gugauaaugu agcgagauuu ucuguugugc uugaucuaac caugugguug cgagguauga 60
guaaaacaug guuccgucaa gcaccaugga acgucacgca gcuuucuaca 110
//
ID hsa-mir-218-2 standard; RNA; HSA; 110 BP.
XX
AC MI0000295;
XX
DE Homo sapiens miR-218-2 stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-218; hsa-miR-218.
DR HGNC; 31596; MIR218-2.
DR ENTREZGENE; 407001; MIR218-2.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised miR
CC has been validated in zebrafish, and the 5' end mapped by PCR. Landgraf
CC et al. confirm expression in human [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 25..45
FT /accession="MIMAT0000275"
FT /product="hsa-miR-218-5p"
FT /evidence=experimental
FT /experiment="cloned [2-3]"
FT /similarity="MI0000957"
FT miRNA 67..88
FT /accession="MIMAT0004566"
FT /product="hsa-miR-218-2-3p"
FT /evidence=experimental
FT /experiment="cloned [2]"
XX
SQ Sequence 110 BP; 23 A; 29 C; 32 G; 0 T; 26 other;
gaccagucgc ugcggggcuu uccuuugugc uugaucuaac cauguggugg aacgauggaa 60
acggaacaug guucugucaa gcaccgcgga aagcaccgug cucuccugca 110
//
ID hsa-mir-219a-1 standard; RNA; HSA; 110 BP.
XX
AC MI0000296;
XX
DE Homo sapiens miR-219a-1 stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 15634332.
RA Weber MJ;
RT "New human and mouse microRNA genes found by homology search";
RL FEBS J. 272:59-73(2005).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-219; hsa-miR-219.
DR HGNC; 31597; MIR219-1.
DR ENTREZGENE; 407002; MIR219-1.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the 5' excised
CC miR has been validated in zebrafish, and the 5' end mapped by PCR [2]. The
CC mature products were later validated in human [3]. Two hairpin precursor
CC structures are predicted, mir-219-1 on chromosome 6 (MIR:MI0000296) and
CC mir-219-2 on chromosome 9 (MIR:MI0000740) [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 21..41
FT /accession="MIMAT0000276"
FT /product="hsa-miR-219a-5p"
FT /evidence=experimental
FT /experiment="cloned [3]"
FT /similarity="MI0001384"
FT miRNA 62..83
FT /accession="MIMAT0004567"
FT /product="hsa-miR-219a-1-3p"
FT /evidence=experimental
FT /experiment="cloned [3]"
XX
SQ Sequence 110 BP; 17 A; 42 C; 33 G; 0 T; 18 other;
ccgccccggg ccgcggcucc ugauugucca aacgcaauuc ucgagucuau ggcuccggcc 60
gagaguugag ucuggacguc ccgagccgcc gcccccaaac cucgagcggg 110
//
ID hsa-mir-221 standard; RNA; HSA; 110 BP.
XX
AC MI0000298;
XX
DE Homo sapiens miR-221 stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
RN [5]
RX PUBMED; 20158877.
RA Koh W, Sheng CT, Tan B, Lee QY, Kuznetsov V, Kiang LS, Tanavde V;
RT "Analysis of deep sequencing microRNA expression profile from human
RT embryonic stem cells derived mesenchymal stem cells reveals possible role
RT of let-7 microRNA family in downstream targeting of hepatic nuclear factor
RT 4 alpha";
RL BMC Genomics. 11 Suppl 1:S6(2010).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-221; hsa-miR-221.
DR HGNC; 31601; MIR221.
DR ENTREZGENE; 407006; MIR221.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised miR
CC has been validated in zebrafish, and later validated in human HL-60
CC leukemia cells [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 25..46
FT /accession="MIMAT0004568"
FT /product="hsa-miR-221-5p"
FT /evidence=experimental
FT /experiment="cloned [3]"
FT miRNA 65..87
FT /accession="MIMAT0000278"
FT /product="hsa-miR-221-3p"
FT /evidence=experimental
FT /experiment="cloned [2-4], Illumina [5]"
FT /similarity="MI0001387"
XX
SQ Sequence 110 BP; 25 A; 24 C; 28 G; 0 T; 33 other;
ugaacaucca ggucuggggc augaaccugg cauacaaugu agauuucugu guucguuagg 60
caacagcuac auugucugcu ggguuucagg cuaccuggaa acauguucuc 110
//
ID hsa-mir-222 standard; RNA; HSA; 110 BP.
XX
AC MI0000299;
XX
DE Homo sapiens miR-222 stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 15183728.
RA Suh MR, Lee Y, Kim JY, Kim SK, Moon SH, Lee JY, Cha KY, Chung HM, Yoon HS,
RA Moon SY, Kim VN, Kim KS;
RT "Human embryonic stem cells express a unique set of microRNAs";
RL Dev Biol. 270:488-498(2004).
XX
RN [3]
RX PUBMED; 15325244.
RA Kasashima K, Nakamura Y, Kozu T;
RT "Altered expression profiles of microRNAs during TPA-induced
RT differentiation of HL-60 cells";
RL Biochem Biophys Res Commun. 322:403-410(2004).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-222; hsa-miR-222.
DR HGNC; 31602; MIR222.
DR ENTREZGENE; 407007; MIR222.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised miR
CC was validated in zebrafish, and the ends mapped by cloning. Subsequent
CC cloning studies have also verified the expression of miR-222 in human ES
CC cells. The mature sequence shown here represents the most commonly cloned
CC form from large-scale cloning studies [4].
XX
FH Key Location/Qualifiers
FH
FT miRNA 31..52
FT /accession="MIMAT0004569"
FT /product="hsa-miR-222-5p"
FT /evidence=experimental
FT /experiment="cloned [4]"
FT miRNA 69..89
FT /accession="MIMAT0000279"
FT /product="hsa-miR-222-3p"
FT /evidence=experimental
FT /experiment="cloned [2-5], Northern [2]"
XX
SQ Sequence 110 BP; 21 A; 27 C; 29 G; 0 T; 33 other;
gcugcuggaa gguguaggua cccucaaugg cucaguagcc aguguagauc cugucuuucg 60
uaaucagcag cuacaucugg cuacuggguc ucugauggca ucuucuagcu 110
//
ID hsa-mir-223 standard; RNA; HSA; 110 BP.
XX
AC MI0000300;
XX
DE Homo sapiens miR-223 stem-loop
XX
RN [1]
RX PUBMED; 12624257.
RA Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP;
RT "Vertebrate microRNA genes";
RL Science. 299:1540(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-223; hsa-miR-223.
DR HGNC; 31603; MIR223.
DR ENTREZGENE; 407008; MIR223.
XX
CC This human miRNA was predicted by computational methods using conservation
CC with mouse and Fugu rubripes sequences [1]. Expression of the excised miR
CC has been validated in zebrafish, and the 5' end mapped by PCR. Landgraf
CC et al. confirm expression in human [2]. The mature sequence shown here
CC represents the most commonly cloned form from large-scale cloning studies
CC [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 26..47
FT /accession="MIMAT0004570"
FT /product="hsa-miR-223-5p"
FT /evidence=experimental
FT /experiment="cloned [2]"
FT miRNA 68..89
FT /accession="MIMAT0000280"
FT /product="hsa-miR-223-3p"
FT /evidence=experimental
FT /experiment="cloned [2]"
FT /similarity="MI0001389"
XX
SQ Sequence 110 BP; 23 A; 31 C; 28 G; 0 T; 28 other;
ccuggccucc ugcagugcca cgcuccgugu auuugacaag cugaguugga cacuccaugu 60
gguagagugu caguuuguca aauaccccaa gugcggcaca ugcuuaccag 110
//
ID hsa-mir-224 standard; RNA; HSA; 81 BP.
XX
AC MI0000301;
XX
DE Homo sapiens miR-224 stem-loop
XX
RN [1]
RX PUBMED; 12554860.
RA Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G;
RT "Numerous microRNPs in neuronal cells containing novel microRNAs";
RL RNA. 9:180-186(2003).
RC Erratum RNA 9:631-632(2003).
XX
RN [2]
RX PUBMED; 15891114.
RA Altuvia Y, Landgraf P, Lithwick G, Elefant N, Pfeffer S, Aravin A,
RA Brownstein MJ, Tuschl T, Margalit H;
RT "Clustering and conservation patterns of human microRNAs";
RL Nucleic Acids Res. 33:2697-2706(2005).
XX
RN [3]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [4]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
RN [5]
RX PUBMED; 19015728.
RA Tzur G, Levy A, Meiri E, Barad O, Spector Y, Bentwich Z, Mizrahi L,
RA Katzenellenbogen M, Ben-Shushan E, Reubinoff BE, Galun E;
RT "MicroRNA expression patterns and function in endodermal differentiation
RT of human embryonic stem cells";
RL PLoS One. 3:e3726(2008).
XX
RN [6]
RX PUBMED; 19144710.
RA Zhu JY, Pfuhl T, Motsch N, Barth S, Nicholls J, Grasser F, Meister G;
RT "Identification of novel Epstein-Barr virus microRNA genes from
RT nasopharyngeal carcinomas";
RL J Virol. 83:3333-3341(2009).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-224; hsa-miR-224.
DR HGNC; 31604; MIR224.
DR ENTREZGENE; 407009; MIR224.
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..31
FT /accession="MIMAT0000281"
FT /product="hsa-miR-224-5p"
FT /evidence=experimental
FT /experiment="cloned [1-4]"
FT miRNA 53..75
FT /accession="MIMAT0009198"
FT /product="hsa-miR-224-3p"
FT /evidence=experimental
FT /experiment="qRT-PCR [5], 454 [6]"
XX
SQ Sequence 81 BP; 19 A; 16 C; 20 G; 0 T; 26 other;
gggcuuucaa gucacuagug guuccguuua guagaugauu gugcauuguu ucaaaauggu 60
gcccuaguga cuacaaagcc c 81
//
ID cel-mir-124 standard; RNA; CEL; 96 BP.
XX
AC MI0000302;
XX
DE Caenorhabditis elegans miR-124 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR WORMBASE; C29E6/8322-8417; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 18..40
FT /accession="MIMAT0015111"
FT /product="cel-miR-124-5p"
FT /evidence=experimental
FT /experiment="CLIPseq [5]"
FT miRNA 61..81
FT /accession="MIMAT0000282"
FT /product="cel-miR-124-3p"
FT /evidence=experimental
FT /experiment="cloned [1], Northern [1], 454 [3], Illumina
FT [4], CLIPseq [5]"
XX
SQ Sequence 96 BP; 21 A; 26 C; 25 G; 0 T; 24 other;
gucccacuug ucaucuggca ugcacccuag ugacuuuagu ggacaucuaa gucuuccaac 60
uaaggcacgc ggugaaugcc acguggccau gauggg 96
//
ID cel-mir-228 standard; RNA; CEL; 98 BP.
XX
AC MI0000303;
XX
DE Caenorhabditis elegans miR-228 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [3]
RX PUBMED; 12769849.
RA Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J;
RT "Computational and experimental identification of C. elegans microRNAs";
RL Mol Cell. 11:1253-1263(2003).
XX
RN [4]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [5]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [6]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [7]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; T12E12/23964-24061; .
XX
CC This precursor sequence was predicted by comparative computational
CC approaches [1,2]. Northern blotting confirmed that the strand containing
CC the predicted miR is predominantly expressed, and the 5' and 3' ends were
CC confirmed later [4].
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..38
FT /accession="MIMAT0000283"
FT /product="cel-miR-228-5p"
FT /evidence=experimental
FT /experiment="cloned [1], Northern [1,3], PCR [3], 454 [4],
FT Illumina [5,7], CLIPseq [6]"
FT miRNA 58..79
FT /accession="MIMAT0020327"
FT /product="cel-miR-228-3p"
FT /evidence=experimental
FT /experiment="Illumina [7]"
XX
SQ Sequence 98 BP; 26 A; 25 C; 25 G; 0 T; 22 other;
ccuuaucccg uucgcaaugg cacugcauga auucacggcu augcauaacg acagaccgcg 60
gaucauacgg uaccauagcg gacggugaug agguuaau 98
//
ID cel-mir-229 standard; RNA; CEL; 115 BP.
XX
AC MI0000304;
XX
DE Caenorhabditis elegans miR-229 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
CC The extents of the dominant mature miRNA species are adjusted here in
CC accordance with a large scale cloning and sequencing study [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 8..33
FT /accession="MIMAT0000284"
FT /product="cel-miR-229-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1], 454 [3], Illumina
FT [4], CLIPseq [5]"
FT miRNA 88..109
FT /accession="MIMAT0015112"
FT /product="cel-miR-229-3p"
FT /evidence=experimental
FT /experiment="CLIPseq [5]"
XX
SQ Sequence 115 BP; 26 A; 27 C; 31 G; 0 T; 31 other;
cgccggcaau gacacugguu aucuuuucca ucguggaaug ccccccauug auuuuuuccc 60
cuuuucgggg ggaaaaaauu ggaaacgaga aagguaucgg gugucauagc cggcg 115
//
ID cel-mir-230 standard; RNA; CEL; 98 BP.
XX
AC MI0000305;
XX
DE Caenorhabditis elegans miR-230 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR WORMBASE; F46G11/21083-21180; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 17..39
FT /accession="MIMAT0015113"
FT /product="cel-miR-230-5p"
FT /evidence=experimental
FT /experiment="CLIPseq [5]"
FT miRNA 61..83
FT /accession="MIMAT0000285"
FT /product="cel-miR-230-3p"
FT /evidence=experimental
FT /experiment="cloned [1], Northern [1], 454 [3], Illumina
FT [4], CLIPseq [5]"
XX
SQ Sequence 98 BP; 27 A; 14 C; 24 G; 0 T; 33 other;
uugauguaau gccgucacuu ggucggcgau uuaauauuau cagaacauag gaaauuguua 60
guauuaguug ugcgaccagg agacgguauu cgcauauu 98
//
ID cel-mir-231 standard; RNA; CEL; 99 BP.
XX
AC MI0000306;
XX
DE Caenorhabditis elegans miR-231 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [6]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; R13A5/6444-6346; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 18..39
FT /accession="MIMAT0020328"
FT /product="cel-miR-231-5p"
FT /evidence=experimental
FT /experiment="Illumina [6]"
FT miRNA 61..84
FT /accession="MIMAT0000286"
FT /product="cel-miR-231-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1], 454 [3], Illumina
FT [4,6], CLIPseq [5]"
XX
SQ Sequence 99 BP; 32 A; 18 C; 19 G; 0 T; 30 other;
uagcaccaca gguuguucug acuguuucaa aagcuuguag uaucuuaaua aauaaacaua 60
uaagcucgug aucaacaggc agaacaacuc gguuuugug 99
//
ID cel-mir-232 standard; RNA; CEL; 98 BP.
XX
AC MI0000307;
XX
DE Caenorhabditis elegans miR-232 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [6]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; F13H10/3269-3172; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 19..41
FT /accession="MIMAT0020777"
FT /product="cel-miR-232-5p"
FT /evidence=experimental
FT /experiment="Illumina [6]"
FT miRNA 61..83
FT /accession="MIMAT0000287"
FT /product="cel-miR-232-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1], 454 [3], Illumina
FT [4,6], CLIPseq [5]"
XX
SQ Sequence 98 BP; 28 A; 16 C; 18 G; 0 T; 36 other;
aaguucaauu uuuggauccc ugcaguuucg augauuuuau ccuuaauucu gaagauguga 60
uaaaugcauc uuaacugcgg ugaucuagau caugaaca 98
//
ID cel-mir-233 standard; RNA; CEL; 98 BP.
XX
AC MI0000308;
XX
DE Caenorhabditis elegans miR-233 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [6]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; W03G11/505-408; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 19..41
FT /accession="MIMAT0020329"
FT /product="cel-miR-233-5p"
FT /evidence=experimental
FT /experiment="Illumina [6]"
FT miRNA 61..83
FT /accession="MIMAT0000288"
FT /product="cel-miR-233-3p"
FT /evidence=experimental
FT /experiment="cloned [1], Northern [1], 454 [3], Illumina
FT [4,6], CLIPseq [5]"
XX
SQ Sequence 98 BP; 24 A; 24 C; 21 G; 0 T; 29 other;
auauagcauc uuucugucuc gcccaucccg uugcuccaau auucuaacaa caagugauua 60
uugagcaaug cgcaugugcg ggauagacug auggcugc 98
//
ID cel-mir-234 standard; RNA; CEL; 96 BP.
XX
AC MI0000309;
XX
DE Caenorhabditis elegans miR-234 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [6]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; C13B4/1971-1876; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..37
FT /accession="MIMAT0020330"
FT /product="cel-miR-234-5p"
FT /evidence=experimental
FT /experiment="Illumina [6]"
FT miRNA 61..81
FT /accession="MIMAT0000289"
FT /product="cel-miR-234-3p"
FT /evidence=experimental
FT /experiment="cloned [1], Northern [1], 454 [3], Illumina
FT [4,6], CLIPseq [5]"
XX
SQ Sequence 96 BP; 34 A; 18 C; 16 G; 0 T; 28 other;
caaaaaauga ucaaacggua uuccagaguu gauaauaaaa augcgucagu ccgcaaucua 60
uuauugcucg agaauacccu uugacuacua ugugua 96
//
ID cel-mir-235 standard; RNA; CEL; 97 BP.
XX
AC MI0000310;
XX
DE Caenorhabditis elegans miR-235 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [6]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; T09B4/12737-12641; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 19..41
FT /accession="MIMAT0020331"
FT /product="cel-miR-235-5p"
FT /evidence=experimental
FT /experiment="Illumina [6]"
FT miRNA 61..82
FT /accession="MIMAT0000290"
FT /product="cel-miR-235-3p"
FT /evidence=experimental
FT /experiment="cloned [1], Northern [1], 454 [3], Illumina
FT [4,6], CLIPseq [5]"
XX
SQ Sequence 97 BP; 27 A; 22 C; 23 G; 0 T; 25 other;
uccgaagaua ucaggaucag gccuuggcug auugcaaaau uguucaccgu gaaaauuaaa 60
uauugcacuc uccccggccu gaucugagag uaaggcg 97
//
ID cel-mir-236 standard; RNA; CEL; 98 BP.
XX
AC MI0000311;
XX
DE Caenorhabditis elegans miR-236 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [3]
RX PUBMED; 12769849.
RA Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J;
RT "Computational and experimental identification of C. elegans microRNAs";
RL Mol Cell. 11:1253-1263(2003).
XX
RN [4]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [5]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [6]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [7]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; C52E12/37215-37118; .
XX
CC This precursor sequence was predicted by comparative computational
CC approaches [1,3]. The excised miRNA sequence was predicted to comprise
CC bases 64 to 87, and the precise 5' and 3' ends were determined later [4].
CC Northern blotting confirmed that the strand containing the predicted miR
CC is predominantly expressed.
XX
FH Key Location/Qualifiers
FH
FT miRNA 19..42
FT /accession="MIMAT0020332"
FT /product="cel-miR-236-5p"
FT /evidence=experimental
FT /experiment="Illumina [7]"
FT miRNA 61..83
FT /accession="MIMAT0000291"
FT /product="cel-miR-236-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2,4], Northern [1,3], PCR [3],
FT Illumina [5,7], CLIPseq [6]"
XX
SQ Sequence 98 BP; 26 A; 20 C; 21 G; 0 T; 31 other;
ucggugaccg auguccagcg ucuuaccugu ucaauauuua gacugacuau caaagagauc 60
uaauacuguc agguaaugac gcuggauugu caugucau 98
//
ID cel-mir-237 standard; RNA; CEL; 99 BP.
XX
AC MI0000312;
XX
DE Caenorhabditis elegans miR-237 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [6]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; F22F1/5536-5634; .
XX
CC The sequence is reported to be related to lin-4 [2]. The extents of the
CC dominant mature miRNA species are adjusted here in accordance with a large
CC scale cloning and sequencing study [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..38
FT /accession="MIMAT0000292"
FT /product="cel-miR-237-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Northern [1], Illumina [4,6],
FT CLIPseq [5]"
FT miRNA 53..74
FT /accession="MIMAT0020333"
FT /product="cel-miR-237-3p"
FT /evidence=experimental
FT /experiment="Illumina [6]"
XX
SQ Sequence 99 BP; 29 A; 21 C; 22 G; 0 T; 27 other;
uucuacauug cguggucccu gagaauucuc gaacagcuuc aaaguguuca agcugucgag 60
uuuugucaag gaccaaacaa uagaagauca cuugggaac 99
//
ID cel-mir-238 standard; RNA; CEL; 98 BP.
XX
AC MI0000313;
XX
DE Caenorhabditis elegans miR-238 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR WORMBASE; K01F9/3114-3017; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..39
FT /accession="MIMAT0015114"
FT /product="cel-miR-238-5p"
FT /evidence=experimental
FT /experiment="CLIPseq [5]"
FT miRNA 61..83
FT /accession="MIMAT0000293"
FT /product="cel-miR-238-3p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Northern [1], Illumina [4],
FT CLIPseq [5]"
XX
SQ Sequence 98 BP; 24 A; 22 C; 20 G; 0 T; 32 other;
ucuccauuga cuguuuggau guucucggac guucaaagcu acauccaaca aauugguagc 60
uuuguacucc gaugccauuc agauaguuau gagccaug 98
//
ID cel-mir-239a standard; RNA; CEL; 98 BP.
XX
AC MI0000314;
XX
DE Caenorhabditis elegans miR-239a stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [6]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; C34E11/1222-1319; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..38
FT /accession="MIMAT0000294"
FT /product="cel-miR-239a-5p"
FT /evidence=experimental
FT /experiment="cloned [1,3], Northern [1], Illumina [4,6],
FT CLIPseq [5]"
FT miRNA 59..80
FT /accession="MIMAT0020334"
FT /product="cel-miR-239a-3p"
FT /evidence=experimental
FT /experiment="Illumina [6]"
XX
SQ Sequence 98 BP; 27 A; 17 C; 18 G; 0 T; 36 other;
uacacguuug caauuuuugu acuacacaua gguacuggac aauuuucaaa auauauccag 60
ugucuagucu agugcaaaca uugcucggug uuguuuga 98
//
ID cel-mir-239b standard; RNA; CEL; 98 BP.
XX
AC MI0000315;
XX
DE Caenorhabditis elegans miR-239b stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 15317971.
RA Ohler U, Yekta S, Lim LP, Bartel DP, Burge CB;
RT "Patterns of flanking sequence conservation and a characteristic upstream
RT motif for microRNA gene identification";
RL RNA. 10:1309-1322(2004).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR WORMBASE; C34E11/176-79; .
XX
CC miR-239b was predicted by computational analysis and conservation in C.
CC elegans and C. briggsae, and the microRNA confirmed by PCR amplification,
CC cloning and sequencing [1]. A large scale cloning and sequencing study
CC finds two dominant mature miRNA products: the second is 1 nt shorter at
CC the 5' end [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..37
FT /accession="MIMAT0000295"
FT /product="cel-miR-239b-5p"
FT /evidence=experimental
FT /experiment="cloned [3], Illumina [4], CLIPseq [5]"
FT /similarity="MI0000314"
FT miRNA 58..79
FT /accession="MIMAT0015115"
FT /product="cel-miR-239b-3p"
FT /evidence=experimental
FT /experiment="CLIPseq [5]"
XX
SQ Sequence 98 BP; 27 A; 16 C; 22 G; 0 T; 33 other;
gcgacagaug caauuuuugu acuacacaaa aguacugguc auuuaaguug aggcucagca 60
cuuuuguggu gugcaaaaau ggcaaguugc uuuuaucu 98
//
ID cel-mir-240 standard; RNA; CEL; 97 BP.
XX
AC MI0000316;
XX
DE Caenorhabditis elegans miR-240 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [3]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [4]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [5]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; C39D10/9215-9311; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 22..44
FT /accession="MIMAT0015116"
FT /product="cel-miR-240-5p"
FT /evidence=experimental
FT /experiment="CLIPseq [4], Illumina [5]"
FT miRNA 61..82
FT /accession="MIMAT0000296"
FT /product="cel-miR-240-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1], Illumina [3,5],
FT CLIPseq [4]"
XX
SQ Sequence 97 BP; 30 A; 18 C; 17 G; 0 T; 32 other;
uuguuagaaa cuuuuucaaa ucgaggauuu ugagacuaga augcuugaau uguacuagca 60
uacuggcccc caaaucuucg cuuagaaaua caguuca 97
//
ID cel-mir-241 standard; RNA; CEL; 96 BP.
XX
AC MI0000317;
XX
DE Caenorhabditis elegans miR-241 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [3]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [4]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [5]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; F56A12/7696-7601; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..36
FT /accession="MIMAT0000297"
FT /product="cel-miR-241-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1], Illumina [3,5],
FT CLIPseq [4]"
FT miRNA 60..81
FT /accession="MIMAT0020335"
FT /product="cel-miR-241-3p"
FT /evidence=experimental
FT /experiment="Illumina [5]"
XX
SQ Sequence 96 BP; 22 A; 19 C; 28 G; 0 T; 27 other;
cggggguguc aaaguugagg uaggugcgag aaaugacggc auccauauag uaaucguuca 60
uugucucuca gcugcuucau cugugacaug gcuacg 96
//
ID cel-mir-242 standard; RNA; CEL; 96 BP.
XX
AC MI0000318;
XX
DE Caenorhabditis elegans miR-242 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [3]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [4]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR WORMBASE; F36A4/35587-35682; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..36
FT /accession="MIMAT0000298"
FT /product="cel-miR-242"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1], Illumina [3],
FT CLIPseq [4]"
XX
SQ Sequence 96 BP; 25 A; 25 C; 23 G; 0 T; 23 other;
uggcucgcga gaguauugcg uaggccuuug cuucgagaga gaagcuucag uucgcagcaa 60
uauccuccgc aaaacuuucc ccggcuaugc aaaaaa 96
//
ID cel-mir-243 standard; RNA; CEL; 98 BP.
XX
AC MI0000319;
XX
DE Caenorhabditis elegans miR-243 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [3]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [4]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR WORMBASE; R08C7/29717-29814; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 20..38
FT /accession="MIMAT0015117"
FT /product="cel-miR-243-5p"
FT /evidence=experimental
FT /experiment="CLIPseq [4]"
FT miRNA 61..83
FT /accession="MIMAT0000299"
FT /product="cel-miR-243-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1], Illumina [3],
FT CLIPseq [4]"
XX
SQ Sequence 98 BP; 22 A; 23 C; 27 G; 0 T; 26 other;
uguucacgca uaagccugau aucucggugc gaucguaccg uaucgcucac acuuagauua 60
cgguacgauc gcggcgggau aucagguacg ugauugga 98
//
ID cel-mir-244 standard; RNA; CEL; 99 BP.
XX
AC MI0000320;
XX
DE Caenorhabditis elegans miR-244 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [3]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [4]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR WORMBASE; T04D1/15168-15070; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..39
FT /accession="MIMAT0000300"
FT /product="cel-miR-244-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1], Illumina [3],
FT CLIPseq [4]"
FT miRNA 58..78
FT /accession="MIMAT0015118"
FT /product="cel-miR-244-3p"
FT /evidence=experimental
FT /experiment="CLIPseq [4]"
XX
SQ Sequence 99 BP; 26 A; 18 C; 19 G; 0 T; 36 other;
cuccauaucu caaucucuuu gguuguacaa agugguaugg cucaucgaau aagcacauac 60
ugcuuuucag cuaaaggaau ugagauuuug uaggcuuuu 99
//
ID cel-mir-245 standard; RNA; CEL; 97 BP.
XX
AC MI0000321;
XX
DE Caenorhabditis elegans miR-245 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [3]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [4]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [5]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; F55D12/9021-9117; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 20..42
FT /accession="MIMAT0020336"
FT /product="cel-miR-245-5p"
FT /evidence=experimental
FT /experiment="Illumina [5]"
FT miRNA 61..82
FT /accession="MIMAT0000301"
FT /product="cel-miR-245-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1], Illumina [3,5],
FT CLIPseq [4]"
XX
SQ Sequence 97 BP; 22 A; 18 C; 19 G; 0 T; 38 other;
cugaauucaa uguuggagag cuauuugcaa gguaccuaau uguuugauua uugauucuca 60
auuggucccc uccaaguagc ucuauugcau uguuugc 97
//
ID cel-mir-246 standard; RNA; CEL; 97 BP.
XX
AC MI0000322;
XX
DE Caenorhabditis elegans miR-246 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [3]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [4]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [5]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; ZK593/30340-30436; .
XX
CC The extents of the dominant mature miRNA species are adjusted here in
CC accordance with a large scale cloning and sequencing study [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 19..41
FT /accession="MIMAT0020337"
FT /product="cel-miR-246-5p"
FT /evidence=experimental
FT /experiment="Illumina [5]"
FT miRNA 61..81
FT /accession="MIMAT0000302"
FT /product="cel-miR-246-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1], Illumina [3,5],
FT CLIPseq [4]"
XX
SQ Sequence 97 BP; 31 A; 17 C; 18 G; 0 T; 31 other;
aucugaauua uaaaacaucg ccuaaccguu gucauguaau auuucccaga gaaaaugaua 60
uuacauguuu cggguaggag cuguucaaac uuuggac 97
//
ID cel-mir-247 standard; RNA; CEL; 98 BP.
XX
AC MI0000323;
XX
DE Caenorhabditis elegans miR-247 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [3]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [4]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR WORMBASE; C39E6/17993-18090; .
XX
CC The extents of the dominant mature miRNA species are adjusted here in
CC accordance with a large scale cloning and sequencing study [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 21..42
FT /accession="MIMAT0015119"
FT /product="cel-miR-247-5p"
FT /evidence=experimental
FT /experiment="CLIPseq [4]"
FT miRNA 61..82
FT /accession="MIMAT0000303"
FT /product="cel-miR-247-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1], Illumina [3],
FT CLIPseq [4]"
XX
SQ Sequence 98 BP; 30 A; 20 C; 18 G; 0 T; 30 other;
auuaccagcu auuuuccaag uagagaaaag uuucuaauua cccaucaugc acaaaugugg 60
ugacuagagc cuauucucuu cuuggaaaag uggcgacu 98
//
ID cel-mir-248 standard; RNA; CEL; 98 BP.
XX
AC MI0000324;
XX
DE Caenorhabditis elegans miR-248 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [3]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [4]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR WORMBASE; AH9/20339-20242; .
XX
CC The extents of the dominant mature miRNA species are adjusted here in
CC accordance with a large scale cloning and sequencing study [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 60..83
FT /accession="MIMAT0000304"
FT /product="cel-miR-248"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1], Illumina [3],
FT CLIPseq [4]"
XX
SQ Sequence 98 BP; 22 A; 25 C; 21 G; 0 T; 30 other;
uuucccggcu gcaacuacgg uaagcgguau ccagccgaug uuuucaauac ugcauuugaa 60
uacacgugca cggauaacgc ucauuguuuu ucgcaugc 98
//
ID cel-mir-249 standard; RNA; CEL; 97 BP.
XX
AC MI0000325;
XX
DE Caenorhabditis elegans miR-249 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [3]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [4]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; Y48D7A/300-204; .
XX
CC The extents of the dominant mature miRNA species are adjusted here in
CC accordance with a large scale cloning and sequencing study [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 17..40
FT /accession="MIMAT0020338"
FT /product="cel-miR-249-5p"
FT /evidence=experimental
FT /experiment="Illumina [4]"
FT miRNA 61..83
FT /accession="MIMAT0000305"
FT /product="cel-miR-249-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Illumina [3-4]"
XX
SQ Sequence 97 BP; 29 A; 22 C; 22 G; 0 T; 24 other;
auacucuuga acgacuagca acgcacaaac gucuucugug cgacaacauc ugaauguuug 60
ucacaggacu uuugagcguu gccagucgaa agaggaa 97
//
ID cel-mir-250 standard; RNA; CEL; 99 BP.
XX
AC MI0000326;
XX
DE Caenorhabditis elegans miR-250 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [3]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [4]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [5]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; F55A11/6590-6492; .
XX
CC The extents of the dominant mature miRNA species are adjusted here in
CC accordance with a large scale cloning and sequencing study [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 18..39
FT /accession="MIMAT0020339"
FT /product="cel-miR-250-5p"
FT /evidence=experimental
FT /experiment="Illumina [5]"
FT miRNA 60..79
FT /accession="MIMAT0000306"
FT /product="cel-miR-250-3p"
FT /evidence=experimental
FT /experiment="Northern [1-2], PCR [1], Illumina [3,5],
FT CLIPseq [4]"
XX
SQ Sequence 99 BP; 24 A; 28 C; 22 G; 0 T; 25 other;
agggucuucg gaccacgccu ucaguugccu cgugauccgc caaacacaau aaauggacga 60
aucacaguca acuguuggca uggugcucgu acccauuuu 99
//
ID cel-mir-251 standard; RNA; CEL; 97 BP.
XX
AC MI0000327;
XX
DE Caenorhabditis elegans miR-251 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [3]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [4]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
DR WORMBASE; F59F3/28031-28127; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 19..40
FT /accession="MIMAT0000307"
FT /product="cel-miR-251"
FT /evidence=experimental
FT /experiment="Northern [1-2], PCR [1], Illumina [3],
FT CLIPseq [4]"
XX
SQ Sequence 97 BP; 30 A; 14 C; 19 G; 0 T; 34 other;
acuuucaaug accccuuguu aaguaguggu gccgcucuua uuagguugaa aaguaauaag 60
aguaguucac uacuuaucaa ggugaaauuu gaaauuu 97
//
ID cel-mir-252 standard; RNA; CEL; 98 BP.
XX
AC MI0000328;
XX
DE Caenorhabditis elegans miR-252 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [3]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [4]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [5]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; W02B12/2049-1952; .
XX
CC The extents of the dominant mature miRNA species are adjusted here in
CC accordance with a large scale cloning and sequencing study [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 21..43
FT /accession="MIMAT0000308"
FT /product="cel-miR-252-5p"
FT /evidence=experimental
FT /experiment="Northern [1-2], PCR [1], Illumina [3,5],
FT CLIPseq [4]"
FT miRNA 60..78
FT /accession="MIMAT0020340"
FT /product="cel-miR-252-3p"
FT /evidence=experimental
FT /experiment="Illumina [5]"
XX
SQ Sequence 98 BP; 26 A; 21 C; 21 G; 0 T; 30 other;
uccagggguc ucuuucaguu auaaguagua gugccgcagg uaaccgccag ucuaaaaggc 60
uuaccuacug ccuucugcuu aaaauugaaa uauugaug 98
//
ID cel-mir-253 standard; RNA; CEL; 107 BP.
XX
AC MI0000329;
XX
DE Caenorhabditis elegans miR-253 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [3]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [4]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [5]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; F44E7/10412-10306; .
XX
CC A mature miRNA product from the 5' arm of this hairpin precursor was first
CC identified [1]. A later large scale cloning and sequencing study
CC identified a 3' product and showed it to be the dominant mature miRNA [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 21..42
FT /accession="MIMAT0000309"
FT /product="cel-miR-253-5p"
FT /evidence=experimental
FT /experiment="Northern [1], PCR [1], CLIPseq [4], Illumina
FT [5]"
FT miRNA 64..85
FT /accession="MIMAT0004215"
FT /product="cel-miR-253-3p"
FT /evidence=experimental
FT /experiment="cloned [2], Illumina [3,5], CLIPseq [4]"
XX
SQ Sequence 107 BP; 24 A; 28 C; 28 G; 0 T; 27 other;
gaauuguucc gaucgccgcu cuuuucacac accucacuaa cacugaccac cgaugcauag 60
auguuaguag gcguuguggg aagggcggcg acagugaacg ucguuuc 107
//
ID cel-mir-254 standard; RNA; CEL; 100 BP.
XX
AC MI0000330;
XX
DE Caenorhabditis elegans miR-254 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [3]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
DR WORMBASE; ZK455/13690-13591; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 19..40
FT /accession="MIMAT0031891"
FT /product="cel-miR-254-5p"
FT /evidence=experimental
FT /experiment="454 [2]"
FT miRNA 59..75
FT /accession="MIMAT0000310"
FT /product="cel-miR-254-3p"
FT /evidence=experimental
FT /experiment="Northern [1-2], PCR [1], Illumina [3]"
XX
SQ Sequence 100 BP; 26 A; 23 C; 22 G; 0 T; 29 other;
acuaugcaua uugccgccua cagaagcaua gauuuccaca aaccauucga gguguuugug 60
caaaucuuuc gcgacuguag gcggcgaaca ugcaguuuuu 100
//
ID cel-mir-255 standard; RNA; CEL; 110 BP.
XX
AC MI0000331;
XX
DE Caenorhabditis elegans miR-255 stem-loop
XX
RN [1]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
RN [2]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [3]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [4]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [5]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; F08F3/31040-31149; .
XX
CC This precursor sequence was identified computationally using sequence
CC homology with C. briggsae [1]. The mature microRNA was identified later
CC [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 25..46
FT /accession="MIMAT0020341"
FT /product="cel-miR-255-5p"
FT /evidence=experimental
FT /experiment="Illumina [5]"
FT miRNA 62..83
FT /accession="MIMAT0004216"
FT /product="cel-miR-255-3p"
FT /evidence=experimental
FT /experiment="cloned [2], Illumina [3,5], CLIPseq [4]"
XX
SQ Sequence 110 BP; 34 A; 15 C; 22 G; 0 T; 39 other;
cagugguucg acuaaauuuu ggagguaaga aaucuuugua guucuccgua uugugacgug 60
aaaacugaag agauuuuuua cagacuucac aaauuugaaa uauauuccug 110
//
ID cel-mir-256 standard; RNA; CEL; 101 BP.
XX
AC MI0000333;
XX
DE Caenorhabditis elegans miR-256 stem-loop
XX
RN [1]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [2]
RX PUBMED; 12672692.
RA Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB,
RA Bartel DP;
RT "The microRNAs of Caenorhabditis elegans";
RL Genes Dev. 17:991-1008(2003).
XX
DR WORMBASE; T07H8/6428-6328; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 66..86
FT /accession="MIMAT0000311"
FT /product="cel-miR-256"
FT /evidence=experimental
FT /experiment="Northern [2]"
XX
SQ Sequence 101 BP; 30 A; 20 C; 30 G; 0 T; 21 other;
gcaaggagug cagaggcuua cuaugagacg gucaagaggc gccuccguca cguggauacg 60
ucggguggaa ugcauagaag acuguacuca aaaaauuuua c 101
//
ID cel-mir-259 standard; RNA; CEL; 101 BP.
XX
AC MI0000336;
XX
DE Caenorhabditis elegans miR-259 stem-loop
XX
RN [1]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
RN [2]
RX PUBMED; 15317971.
RA Ohler U, Yekta S, Lim LP, Bartel DP, Burge CB;
RT "Patterns of flanking sequence conservation and a characteristic upstream
RT motif for microRNA gene identification";
RL RNA. 10:1309-1322(2004).
XX
RN [3]
RX PUBMED; 17174894.
RA Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP;
RT "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and
RT endogenous siRNAs in C. elegans";
RL Cell. 127:1193-1207(2006).
XX
RN [4]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
RN [5]
RX PUBMED; 20062054.
RA Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo
RA GW;
RT "Comprehensive discovery of endogenous Argonaute binding sites in
RT Caenorhabditis elegans";
RL Nat Struct Mol Biol. 17:173-179(2010).
XX
RN [6]
RX PUBMED; 21307183.
RA Warf MB, Johnson WE, Bass BL;
RT "Improved annotation of C. elegans microRNAs by deep sequencing reveals
RT structures associated with processing by Drosha and Dicer";
RL RNA. 17:563-577(2011).
XX
DR WORMBASE; F25D1/9529-9429; .
XX
CC miR-259 was predicted by computational analysis and conservation in C.
CC elegans and C. briggsae, and the microRNA confirmed by PCR amplification,
CC cloning and sequencing [1].
XX
FH Key Location/Qualifiers
FH
FT miRNA 19..42
FT /accession="MIMAT0000314"
FT /product="cel-miR-259-5p"
FT /evidence=experimental
FT /experiment="cloned [1-3], Illumina [4,6], CLIPseq [5]"
FT miRNA 57..80
FT /accession="MIMAT0020342"
FT /product="cel-miR-259-3p"
FT /evidence=experimental
FT /experiment="Illumina [6]"
XX
SQ Sequence 101 BP; 26 A; 20 C; 19 G; 0 T; 36 other;
ucagucauug aaacgaguaa aucucauccu aaucugguag caucuuucga accuugccac 60
cgauuuggca ugggauugac uuguuaaaua gugacuuuuu u 101
//
ID cel-mir-261 standard; RNA; CEL; 99 BP.
XX
AC MI0000338;
XX
DE Caenorhabditis elegans miR-261 stem-loop
XX
RN [1]
RX PUBMED; 12747828.
RA Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D;
RT "MicroRNAs and other tiny endogenous RNAs in C. elegans";
RL Curr Biol. 13:807-818(2003).
XX
DR WORMBASE; B0034/25192-25290; .
XX
FH Key Location/Qualifiers
FH
FT miRNA 66..84
FT /accession="MIMAT0000316"
FT /product="cel-miR-261"
FT /evidence=experimental
FT /experiment="cloned [1]"
XX
SQ Sequence 99 BP; 28 A; 13 C; 21 G; 0 T; 37 other;
ugauggcuuu ucuggauuug uucccuucac guguagaaag aaacgagcaa aaaaaaucuu 60
aguguuagcu uuuuaguuuu cacggugaau auggauauu 99
//
ID hsa-mir-200b standard; RNA; HSA; 95 BP.
XX
AC MI0000342;
XX
DE Homo sapiens miR-200b stem-loop
XX
RN [1]
RX PUBMED; 12769849.
RA Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J;
RT "Computational and experimental identification of C. elegans microRNAs";
RL Mol Cell. 11:1253-1263(2003).
XX
RN [2]
RX PUBMED; 14573789.
RA Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ;
RT "Reduced accumulation of specific microRNAs in colorectal neoplasia";
RL Mol Cancer Res. 1:882-891(2003).
XX
RN [3]
RX PUBMED; 15891114.
RA Altuvia Y, Landgraf P, Lithwick G, Elefant N, Pfeffer S, Aravin A,
RA Brownstein MJ, Tuschl T, Margalit H;
RT "Clustering and conservation patterns of human microRNAs";
RL Nucleic Acids Res. 33:2697-2706(2005).
XX
RN [4]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [5]
RX PUBMED; 17616659.
RA Lui WO, Pourmand N, Patterson BK, Fire A;
RT "Patterns of known and novel small RNAs in human cervical cancer";
RL Cancer Res. 67:6031-6043(2007).
XX
DR TARGETS:PICTAR-VERT; hsa-miR-200b; hsa-miR-200b.
DR HGNC; 31579; MIR200B.
DR ENTREZGENE; 406984; MIR200B.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [4].
XX
FH Key Location/Qualifiers
FH
FT miRNA 21..42
FT /accession="MIMAT0004571"
FT /product="hsa-miR-200b-5p"
FT /evidence=experimental
FT /experiment="cloned [4]"
FT miRNA 57..78
FT /accession="MIMAT0000318"
FT /product="hsa-miR-200b-3p"
FT /evidence=experimental
FT /experiment="Northern [1], cloned [2-5]"
XX
SQ Sequence 95 BP; 18 A; 26 C; 31 G; 0 T; 20 other;
ccagcucggg cagccguggc caucuuacug ggcagcauug gauggaguca ggucucuaau 60
acugccuggu aaugaugacg gcggagcccu gcacg 95
//
ID dme-mir-263a standard; RNA; DME; 94 BP.
XX
AC MI0000343;
XX
DE Drosophila melanogaster miR-263a stem-loop
XX
RN [1]
RX PUBMED; 12769849.
RA Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J;
RT "Computational and experimental identification of C. elegans microRNAs";
RL Mol Cell. 11:1253-1263(2003).
XX
RN [2]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [3]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [4]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-263a; miR-263a.
DR TARGETS:PICTAR-FLY; dme-miR-263a; dme-miR-263a.
XX
FH Key Location/Qualifiers
FH
FT miRNA 18..41
FT /accession="MIMAT0000319"
FT /product="dme-miR-263a-5p"
FT /evidence=experimental
FT /experiment="Northern [1], 454 [3-4], Illumina [4]"
FT /similarity="MI0000343"
FT miRNA 59..80
FT /accession="MIMAT0020799"
FT /product="dme-miR-263a-3p"
FT /evidence=not_experimental
XX
SQ Sequence 94 BP; 27 A; 17 C; 23 G; 0 T; 27 other;
uagaucucgg cacaguuaau ggcacuggaa gaauucacgg gguaauuuuu auacaacccg 60
ugaucucuua guggcaucua uggugcgaga auaa 94
//
ID cel-mir-264 standard; RNA; CEL; 93 BP.
XX
AC MI0000344;
XX
DE Caenorhabditis elegans miR-264 stem-loop
XX
RN [1]
RX PUBMED; 12769849.
RA Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J;
RT "Computational and experimental identification of C. elegans microRNAs";
RL Mol Cell. 11:1253-1263(2003).
XX
CC This precursor sequence was predicted by comparative computational
CC approaches. The excised miRNA sequence is predicted and the precise 5'
CC or 3' end unknown. A PCR amplification protocol confirmed that the
CC strand containing the predicted miR is predominantly expressed.
XX
FH Key Location/Qualifiers
FH
FT miRNA 60..79
FT /accession="MIMAT0000320"
FT /product="cel-miR-264"
FT /evidence=experimental
FT /experiment="PCR [1]"
XX
SQ Sequence 93 BP; 15 A; 23 C; 31 G; 0 T; 24 other;
uggcggcggu cgacauguac auaucaccag ucuggcuuuu cccguuuccg cgagcaagcg 60
gcgggugguu guuguuaugg gauaccggag cca 93
//
ID cel-mir-265 standard; RNA; CEL; 86 BP.
XX
AC MI0000345;
XX
DE Caenorhabditis elegans miR-265 stem-loop
XX
RN [1]
RX PUBMED; 12769849.
RA Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J;
RT "Computational and experimental identification of C. elegans microRNAs";
RL Mol Cell. 11:1253-1263(2003).
XX
CC This precursor sequence was predicted by comparative computational
CC approaches. The excised miRNA sequence is predicted and the precise 5'
CC or 3' end unknown. A PCR amplification protocol confirmed that the
CC strand containing the predicted miR is predominantly expressed.
XX
FH Key Location/Qualifiers
FH
FT miRNA 60..79
FT /accession="MIMAT0000321"
FT /product="cel-miR-265"
FT /evidence=experimental
FT /experiment="PCR [1]"
XX
SQ Sequence 86 BP; 14 A; 18 C; 25 G; 0 T; 29 other;
gguuugacuu acccccuccu uccgcuggcc gccguuuuua uuaugaacuu gaugugguuu 60
gagggaggaa gggugguauu ugaacc 86
//
ID cel-mir-266 standard; RNA; CEL; 94 BP.
XX
AC MI0000346;
XX
DE Caenorhabditis elegans miR-266 stem-loop
XX
RN [1]
RX PUBMED; 12769849.
RA Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J;
RT "Computational and experimental identification of C. elegans microRNAs";
RL Mol Cell. 11:1253-1263(2003).
XX
RN [2]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
CC This precursor sequence was predicted by comparative computational
CC approaches. The excised miRNA sequence is predicted and the precise 5'
CC or 3' end unknown. A PCR amplification protocol confirmed that the
CC strand containing the predicted miR is predominantly expressed.
XX
FH Key Location/Qualifiers
FH
FT miRNA 23..42
FT /accession="MIMAT0000322"
FT /product="cel-miR-266"
FT /evidence=experimental
FT /experiment="PCR [1], Illumina [2]"
XX
SQ Sequence 94 BP; 28 A; 21 C; 18 G; 0 T; 27 other;
ugucuaaacu ugggcaaaag uuaggcaaga cuuuggcaaa gcuugaaucc aaguuuugcc 60
aaaguuuugc ccaacuuuug cccaaauuca gcca 94
//
ID cel-mir-267 standard; RNA; CEL; 93 BP.
XX
AC MI0000347;
XX
DE Caenorhabditis elegans miR-267 stem-loop
XX
RN [1]
RX PUBMED; 12769849.
RA Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J;
RT "Computational and experimental identification of C. elegans microRNAs";
RL Mol Cell. 11:1253-1263(2003).
XX
CC This precursor sequence was predicted by comparative computational
CC approaches. The excised miRNA sequence is predicted and the precise 5'
CC or 3' end unknown. A PCR amplification protocol confirmed that the
CC strand containing the predicted miR is predominantly expressed.
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..35
FT /accession="MIMAT0000323"
FT /product="cel-miR-267"
FT /evidence=experimental
FT /experiment="PCR [1]"
XX
SQ Sequence 93 BP; 27 A; 18 C; 18 G; 0 T; 30 other;
uaaaaguuuc aaaaccccgu gaagugucug cugcaaucua aauuuuuaga uauagaugca 60
gucgacucuu cauuggguuu ucaggaaccc gua 93
//
ID cel-mir-268 standard; RNA; CEL; 95 BP.
XX
AC MI0000348;
XX
DE Caenorhabditis elegans miR-268 stem-loop
XX
RN [1]
RX PUBMED; 12769849.
RA Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J;
RT "Computational and experimental identification of C. elegans microRNAs";
RL Mol Cell. 11:1253-1263(2003).
XX
CC This precursor sequence was predicted by comparative computational
CC approaches. The excised miRNA sequence is predicted and the precise 5'
CC or 3' end unknown. A PCR amplification protocol confirmed that the
CC strand containing the predicted miR is predominantly expressed.
XX
FH Key Location/Qualifiers
FH
FT miRNA 18..41
FT /accession="MIMAT0000324"
FT /product="cel-miR-268"
FT /evidence=experimental
FT /experiment="PCR [1]"
XX
SQ Sequence 95 BP; 19 A; 19 C; 21 G; 0 T; 36 other;
ggaaguggcu uugaagcggc aagaauuaga agcaguuugg ugucagacac acuacucacu 60
cacugcuucu uguuuuuucu gcuuucuuug cuuuu 95
//
ID cel-mir-269 standard; RNA; CEL; 94 BP.
XX
AC MI0000349;
XX
DE Caenorhabditis elegans miR-269 stem-loop
XX
RN [1]
RX PUBMED; 12769849.
RA Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J;
RT "Computational and experimental identification of C. elegans microRNAs";
RL Mol Cell. 11:1253-1263(2003).
XX
CC This precursor sequence was predicted by comparative computational
CC approaches. The excised miRNA sequence is predicted and the precise 5'
CC or 3' end unknown. A PCR amplification protocol confirmed that the
CC strand containing the predicted miR is predominantly expressed.
XX
FH Key Location/Qualifiers
FH
FT miRNA 13..32
FT /accession="MIMAT0000325"
FT /product="cel-miR-269"
FT /evidence=experimental
FT /experiment="PCR [1]"
XX
SQ Sequence 94 BP; 26 A; 21 C; 20 G; 0 T; 27 other;
gggcaaaagu ugggcaagac ucuggcaaaa cuuggauuua ugcugcgcca aaguuuaacc 60
caaguuugac ccaacucuug ucaaauuuuu gucc 94
//
ID cel-mir-270 standard; RNA; CEL; 95 BP.
XX
AC MI0000350;
XX
DE Caenorhabditis elegans miR-270 stem-loop
XX
RN [1]
RX PUBMED; 12769849.
RA Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J;
RT "Computational and experimental identification of C. elegans microRNAs";
RL Mol Cell. 11:1253-1263(2003).
XX
CC This sequence was predicted by computational approaches and validated
CC using a PCR amplification protocol.
XX
FH Key Location/Qualifiers
FH
FT miRNA 64..83
FT /accession="MIMAT0000326"
FT /product="cel-miR-270"
FT /evidence=experimental
FT /experiment="PCR [1]"
XX
SQ Sequence 95 BP; 20 A; 26 C; 26 G; 0 T; 23 other;
gucgcuagcc ucuuuaccug ccuacacacc uuucugccua cguggcacau ugguaggcaa 60
gagggcauga uguagcagug gagauggacu gccac 95
//
ID cel-mir-271 standard; RNA; CEL; 94 BP.
XX
AC MI0000351;
XX
DE Caenorhabditis elegans miR-271 stem-loop
XX
RN [1]
RX PUBMED; 12769849.
RA Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J;
RT "Computational and experimental identification of C. elegans microRNAs";
RL Mol Cell. 11:1253-1263(2003).
XX
CC This sequence was predicted by computational approaches and validated
CC using a PCR amplification protocol.
XX
FH Key Location/Qualifiers
FH
FT miRNA 24..43
FT /accession="MIMAT0000327"
FT /product="cel-miR-271"
FT /evidence=experimental
FT /experiment="PCR [1]"
XX
SQ Sequence 94 BP; 23 A; 27 C; 25 G; 0 T; 19 other;
aauagaaaac ggggcccgcc ggcucgccgg guggaaagca uucgacagca agacguguuu 60
uucaaucugc gacucggcga uucccaucau cacu 94
//
ID cel-mir-272 standard; RNA; CEL; 95 BP.
XX
AC MI0000352;
XX
DE Caenorhabditis elegans miR-272 stem-loop
XX
RN [1]
RX PUBMED; 12769849.
RA Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J;
RT "Computational and experimental identification of C. elegans microRNAs";
RL Mol Cell. 11:1253-1263(2003).
XX
RN [2]
RX PUBMED; 19460142.
RA Kato M, de Lencastre A, Pincus Z, Slack FJ;
RT "Dynamic expression of small non-coding RNAs, including novel microRNAs
RT and piRNAs/21U-RNAs, during Caenorhabditis elegans development";
RL Genome Biol. 10:R54(2009).
XX
CC This sequence was predicted by computational approaches and validated
CC using a PCR amplification protocol.
XX
FH Key Location/Qualifiers
FH
FT miRNA 67..84
FT /accession="MIMAT0000328"
FT /product="cel-miR-272"
FT /evidence=experimental
FT /experiment="PCR [1], Illumina [2]"
XX
SQ Sequence 95 BP; 20 A; 18 C; 38 G; 0 T; 19 other;
cgcaggcacg ugcagguaug uaggcaggcg uaggcccgua ggcaagugua ggucugcagg 60
caugaaugua ggcaugggug uuuggaagac cugcg 95
//
ID cel-mir-273 standard; RNA; CEL; 94 BP.
XX
AC MI0000353;
XX
DE Caenorhabditis elegans miR-273 stem-loop
XX
RN [1]
RX PUBMED; 12769849.
RA Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J;
RT "Computational and experimental identification of C. elegans microRNAs";
RL Mol Cell. 11:1253-1263(2003).
XX
CC This sequence was predicted by computational approaches and validated
CC using a PCR amplification protocol.
XX
FH Key Location/Qualifiers
FH
FT miRNA 59..78
FT /accession="MIMAT0000329"
FT /product="cel-miR-273"
FT /evidence=experimental
FT /experiment="PCR [1]"
XX
SQ Sequence 94 BP; 17 A; 19 C; 24 G; 0 T; 34 other;
accucguuuu gggagcagcc ggcauuuuac gggcuacacu uuuuuuaaaa uugaugugug 60
cccguacugu gucggcugcu uugaaaauuu cggu 94
//
ID dme-mir-184 standard; RNA; DME; 100 BP.
XX
AC MI0000354;
XX
DE Drosophila melanogaster miR-184 stem-loop
XX
RN [1]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [2]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [3]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [4]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-184; miR-184.
DR TARGETS:MIRTE; miR-184S; miR-184S.
DR TARGETS:PICTAR-FLY; dme-miR-184; dme-miR-184.
DR TARGETS:PICTAR-FLY; dme-miR-184*; dme-miR-184*.
XX
CC miR-184 was reported independently in references [1] and [2].
CC Computational prediction followed by northern blotting confirmed that the
CC strand containing the predicted miR is predominantly expressed [1].
CC Reference [2] confirmed the 5' end of the excised miRNA by cloning and
CC reported a length distribution of 19-23 nt with 22 nt the most commonly
CC expressed. They also reported the less predominantly expressed sequence
CC miR-184* from the opposite 5' arm.
XX
FH Key Location/Qualifiers
FH
FT miRNA 22..42
FT /accession="MIMAT0000330"
FT /product="dme-miR-184-5p"
FT /evidence=experimental
FT /experiment="cloned [2], 454 [3-4], Illumina [4]"
FT /similarity="MI0000354"
FT miRNA 61..82
FT /accession="MIMAT0000331"
FT /product="dme-miR-184-3p"
FT /evidence=experimental
FT /experiment="Northern [1], cloned [2], 454 [3-4], Illumina
FT [4]"
FT /similarity="MI0000354"
XX
SQ Sequence 100 BP; 23 A; 28 C; 23 G; 0 T; 26 other;
gguuggccgg ugcauucgua cccuuaucau ucucucgccc cgugugcacu uaaagacaac 60
uggacggaga acugauaagg gcucguauca ccaauucauc 100
//
ID dme-mir-274 standard; RNA; DME; 100 BP.
XX
AC MI0000355;
XX
DE Drosophila melanogaster miR-274 stem-loop
XX
RN [1]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [2]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [3]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-274; miR-274.
XX
CC This sequence is computationally predicted based on conservation in D.
CC pseudoobscura. The precise 5' or 3' ends are unknown. Northern blotting
CC confirmed that the strand containing the predicted miR is predominantly
CC expressed.
XX
FH Key Location/Qualifiers
FH
FT miRNA 20..42
FT /accession="MIMAT0000332"
FT /product="dme-miR-274-5p"
FT /evidence=experimental
FT /experiment="Northern [1], 454 [2-3], Illumina [3]"
FT /similarity="MI0000355"
FT miRNA 64..86
FT /accession="MIMAT0020800"
FT /product="dme-miR-274-3p"
FT /evidence=not_experimental
XX
SQ Sequence 100 BP; 23 A; 20 C; 23 G; 0 T; 34 other;
uccuguguug caguuucguu uugugaccga cacuaacggg uaauuguuug gccgccagga 60
uuacucguuu uugcgaucac aaauuaugaa auugcagcaa 100
//
ID dme-mir-275 standard; RNA; DME; 98 BP.
XX
AC MI0000356;
XX
DE Drosophila melanogaster miR-275 stem-loop
XX
RN [1]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [2]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [3]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [4]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-275; miR-275.
DR TARGETS:PICTAR-FLY; dme-miR-275; dme-miR-275.
XX
CC miR-275 was reported independently in references [1] and [2].
CC Computational prediction followed by northern blotting confirmed that the
CC strand containing the predicted miR is predominantly expressed [1].
CC Reference [2] confirmed the 5' end of the excised miRNA by cloning and
CC reported a length distribution of 19-25 nt with 22 nt the most commonly
CC expressed.
XX
FH Key Location/Qualifiers
FH
FT miRNA 20..42
FT /accession="MIMAT0020801"
FT /product="dme-miR-275-5p"
FT /evidence=not_experimental
FT miRNA 59..81
FT /accession="MIMAT0000333"
FT /product="dme-miR-275-3p"
FT /evidence=experimental
FT /experiment="Northern [1], cloned [2], 454 [3-4], Illumina
FT [4]"
FT /similarity="MI0000356"
XX
SQ Sequence 98 BP; 22 A; 21 C; 27 G; 0 T; 28 other;
uguaaagucu ccuaccuugc gcgcuaauca gugaccgggg cugguuuuuu auauacaguc 60
agguaccuga aguagcgcgc gugguggcag acauauau 98
//
ID dme-mir-92a standard; RNA; DME; 95 BP.
XX
AC MI0000357;
XX
DE Drosophila melanogaster miR-92a stem-loop
XX
RN [1]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [2]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [3]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [4]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [5]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-92a; miR-92a.
DR TARGETS:PICTAR-FLY; dme-miR-92a; dme-miR-92a.
XX
CC miR-92a was reported independently in references [1] and [2].
CC Computational prediction followed by northern blotting confirmed that the
CC strand containing the predicted miR is predominantly expressed [1].
CC Reference [2] confirmed the 5' end of the excised miRNA by cloning and
CC reported a length distribution of 22-25 nt with 22 nt the most commonly
CC expressed.
XX
FH Key Location/Qualifiers
FH
FT miRNA 17..38
FT /accession="MIMAT0020802"
FT /product="dme-miR-92a-5p"
FT /evidence=not_experimental
FT miRNA 55..76
FT /accession="MIMAT0000334"
FT /product="dme-miR-92a-3p"
FT /evidence=experimental
FT /experiment="cloned [2], Northern [3], 454 [4-5], Illumina
FT [5]"
FT /similarity="MI0000357"
XX
SQ Sequence 95 BP; 26 A; 18 C; 23 G; 0 T; 28 other;
aauaugaauu ucccguagga cgggaaggug ucaacguuuu gcauuucgaa uaaacauugc 60
acuugucccg gccuaugggc gguuuguaau aaaca 95
//
ID dme-mir-219 standard; RNA; DME; 100 BP.
XX
AC MI0000358;
XX
DE Drosophila melanogaster miR-219 stem-loop
XX
RN [1]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [2]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [3]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-219; miR-219.
DR TARGETS:PICTAR-FLY; dme-miR-219; dme-miR-219.
XX
CC This sequence is computationally predicted based on conservation in D.
CC pseudoobscura [1]. The sequence of the excised miR is strikingly
CC conserved in human (MIR:MI0000296), but the expression of the miR has not
CC been confirmed in fly and the precise 5' or 3' ends are unknown.
XX
FH Key Location/Qualifiers
FH
FT miRNA 19..39
FT /accession="MIMAT0000335"
FT /product="dme-miR-219-5p"
FT /evidence=experimental
FT /experiment="454 [2-3], Illumina [3]"
FT /similarity="MI0000358"
FT /similarity="MI0001384"
FT miRNA 59..80
FT /accession="MIMAT0020803"
FT /product="dme-miR-219-3p"
FT /evidence=not_experimental
XX
SQ Sequence 100 BP; 30 A; 18 C; 20 G; 0 T; 32 other;
uaauucgauu uuuagcuaug auuguccaaa cgcaauucuu guugauauuc aauauucaag 60
gguugcgacu gggcaucgcg gcucgaaaua agaauacaac 100
//
ID dme-mir-276a standard; RNA; DME; 98 BP.
XX
AC MI0000359;
XX
DE Drosophila melanogaster miR-276a stem-loop
XX
RN [1]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [2]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [3]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [4]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-276a; miR-276a.
DR TARGETS:MIRTE; miR-276aS; miR-276aS.
DR TARGETS:PICTAR-FLY; dme-miR-276a; dme-miR-276a.
XX
CC miR-276 was reported independently in references [1] and [2]. Reference
CC [2] reported a 22 nt excised sequence from the 3' arm of the precursor by
CC cloning. Computational approaches followed by Northern blotting predicted
CC an excised sequence from the 5' arm which is designated miR-276a* here
CC [1].
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..38
FT /accession="MIMAT0000336"
FT /product="dme-miR-276a-5p"
FT /evidence=experimental
FT /experiment="Northern [1], 454 [3-4], Illumina [4]"
FT /similarity="MI0000359"
FT miRNA 54..75
FT /accession="MIMAT0000337"
FT /product="dme-miR-276a-3p"
FT /evidence=experimental
FT /experiment="Northern [1], cloned [2], 454 [3-4], Illumina
FT [4]"
FT /similarity="MI0000359"
XX
SQ Sequence 98 BP; 30 A; 23 C; 19 G; 0 T; 26 other;
ccugguuuuu gccaucagcg agguauagag uuccuacguu cauuauaaac ucguaggaac 60
uucauaccgu gcucuuggaa gaccaaaaaa caaccaag 98
//
ID dme-mir-277 standard; RNA; DME; 100 BP.
XX
AC MI0000360;
XX
DE Drosophila melanogaster miR-277 stem-loop
XX
RN [1]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [2]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [3]
RX PUBMED; 14691535.
RA Stark A, Brennecke J, Russell RB, Cohen SM;
RT "Identification of Drosophila MicroRNA targets";
RL PLoS Biol. 1:E60(2003).
XX
RN [4]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [5]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-277; miR-277.
DR TARGETS:PICTAR-FLY; dme-miR-277; dme-miR-277.
XX
CC miR-277 was reported independently in references [1] and [2].
CC Computational prediction followed by northern blotting confirmed that the
CC strand containing the predicted miR is predominantly expressed [1].
CC Reference [2] confirmed the 5' end of the excised miRNA by cloning and
CC reported a length distribution of 21-23 nt with 23 nt the most commonly
CC expressed. Stark et al. [3] have predicted that miR-277 controls the
CC pathway for valine, leucine and isoleucine degradation by downregulating
CC many of its enzymes.
XX
FH Key Location/Qualifiers
FH
FT miRNA 18..38
FT /accession="MIMAT0020804"
FT /product="dme-miR-277-5p"
FT /evidence=not_experimental
FT miRNA 59..81
FT /accession="MIMAT0000338"
FT /product="dme-miR-277-3p"
FT /evidence=experimental
FT /experiment="Northern [1], cloned [2], 454 [4-5], Illumina
FT [5]"
FT /similarity="MI0000360"
XX
SQ Sequence 100 BP; 27 A; 19 C; 24 G; 0 T; 30 other;
uugaagguuu ugggcugcgu gucaggagug cauuugcacu gaaacuaucu gaagcaugua 60
aaugcacuau cugguacgac auuccagaac guacaaucuu 100
//
ID dme-mir-278 standard; RNA; DME; 98 BP.
XX
AC MI0000361;
XX
DE Drosophila melanogaster miR-278 stem-loop
XX
RN [1]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [2]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [3]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [4]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
CC miR-278 was reported independently in references [1] and [2].
CC Computational prediction followed by northern blotting confirmed that the
CC strand containing the predicted miR is predominantly expressed [1].
CC Reference [2] confirmed the 5' end of the excised miRNA by cloning and
CC reported a length distribution of 20-22 nt with 22 nt the most commonly
CC expressed.
XX
FH Key Location/Qualifiers
FH
FT miRNA 18..40
FT /accession="MIMAT0020805"
FT /product="dme-miR-278-5p"
FT /evidence=not_experimental
FT miRNA 57..78
FT /accession="MIMAT0000339"
FT /product="dme-miR-278-3p"
FT /evidence=experimental
FT /experiment="Northern [1-2], cloned [2], 454 [3-4],
FT Illumina [4]"
FT /similarity="MI0000361"
XX
SQ Sequence 98 BP; 21 A; 21 C; 29 G; 0 T; 27 other;
guaaugguac ggugcgaccg gaugaugguu cacaacgacc gugucauuua aacgggucgg 60
ugggacuuuc guccguuugu aacgccauuu gucaacga 98
//
ID dme-mir-133 standard; RNA; DME; 98 BP.
XX
AC MI0000362;
XX
DE Drosophila melanogaster miR-133 stem-loop
XX
RN [1]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [2]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [3]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [4]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [5]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-133; miR-133.
DR TARGETS:PICTAR-FLY; dme-miR-133; dme-miR-133.
XX
CC miR-133 was reported independently by three groups using computational
CC prediction [2], Northern blot analysis [1] and cloning [3]. References
CC [1] and [2] confirmed that the strand containing the predicted miR is
CC predominantly expressed [1]. Reference [3] confirmed the ends of the
CC excised miRNA by cloning.
XX
FH Key Location/Qualifiers
FH
FT miRNA 19..41
FT /accession="MIMAT0020806"
FT /product="dme-miR-133-5p"
FT /evidence=not_experimental
FT miRNA 57..78
FT /accession="MIMAT0000340"
FT /product="dme-miR-133-3p"
FT /evidence=experimental
FT /experiment="Northern [1,3], 454 [4-5], Illumina [5]"
FT /similarity="MI0000362"
XX
SQ Sequence 98 BP; 21 A; 24 C; 24 G; 0 T; 29 other;
accugcaaca cuguguguag cugguugaca ucgggucaga ucuguuuuuc aagcauuugg 60
uccccuucaa ccagcuguag ccagugguug augacaac 98
//
ID dme-mir-279 standard; RNA; DME; 100 BP.
XX
AC MI0000363;
XX
DE Drosophila melanogaster miR-279 stem-loop
XX
RN [1]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [2]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [3]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [4]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-279; miR-279.
DR TARGETS:PICTAR-FLY; dme-miR-279; dme-miR-279.
XX
CC miR-279 was reported independently in references [1] and [2].
CC Computational prediction followed by northern blotting confirmed that the
CC strand containing the predicted miR is predominantly expressed [1].
CC Reference [2] confirmed the ends of the excised miRNA by cloning.
XX
FH Key Location/Qualifiers
FH
FT miRNA 22..47
FT /accession="MIMAT0020807"
FT /product="dme-miR-279-5p"
FT /evidence=not_experimental
FT miRNA 67..88
FT /accession="MIMAT0000341"
FT /product="dme-miR-279-3p"
FT /evidence=experimental
FT /experiment="Northern [1], cloned [2], 454 [3-4], Illumina
FT [4]"
FT /similarity="MI0000363"
XX
SQ Sequence 100 BP; 23 A; 16 C; 22 G; 0 T; 39 other;
ggaauucaua cuacuguuuu uagugggugg ggguccagug uuucacauug auuuucuuag 60
uauuugugac uagauccaca cucauuaaua acgguaguuc 100
//
ID dme-mir-33 standard; RNA; DME; 99 BP.
XX
AC MI0000364;
XX
DE Drosophila melanogaster miR-33 stem-loop
XX
RN [1]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [2]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [3]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-33; miR-33.
DR TARGETS:PICTAR-FLY; dme-miR-33; dme-miR-33.
XX
FH Key Location/Qualifiers
FH
FT miRNA 26..46
FT /accession="MIMAT0000342"
FT /product="dme-miR-33-5p"
FT /evidence=experimental
FT /experiment="454 [2-3], Illumina [3]"
FT miRNA 65..86
FT /accession="MIMAT0020808"
FT /product="dme-miR-33-3p"
FT /evidence=not_experimental
XX
SQ Sequence 99 BP; 22 A; 26 C; 21 G; 0 T; 30 other;
cucuuccucu ggagaugaca cgaaggugca uuguagucgc auugucuguc ccaauugcuu 60
caggcaauac aacuucagug caagcucugu gcauuucac 99
//
ID dme-mir-280 standard; RNA; DME; 95 BP.
XX
AC MI0000365;
XX
DE Drosophila melanogaster miR-280 stem-loop
XX
RN [1]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
DR TARGETS:MIRTE; miR-280; miR-280.
DR TARGETS:PICTAR-FLY; dme-miR-280; dme-miR-280.
XX
CC This sequence is computationally predicted based on conservation in D.
CC pseudoobscura. The precise 5' or 3' ends are unknown. Northern blotting
CC confirmed that the strand containing the predicted miR is predominantly
CC expressed.
XX
FH Key Location/Qualifiers
FH
FT miRNA 10..36
FT /accession="MIMAT0000343"
FT /product="dme-miR-280-5p"
FT /evidence=experimental
FT /experiment="Northern [1]"
FT /similarity="MI0000365"
XX
SQ Sequence 95 BP; 28 A; 13 C; 18 G; 0 T; 36 other;
uggcuuuuau guauuuacgu ugcauaugaa augauauuua uaguaaacag auuauuuuau 60
augcagguau augcaagucg agguccucca cacug 95
//
ID dme-mir-281-1 standard; RNA; DME; 90 BP.
XX
AC MI0000366;
XX
DE Drosophila melanogaster miR-281-1 stem-loop
XX
RN [1]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [2]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [3]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [4]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-281; miR-281.
DR TARGETS:MIRTE; miR-281aS; miR-281aS.
DR TARGETS:PICTAR-FLY; dme-miR-281; dme-miR-281.
DR TARGETS:PICTAR-FLY; dme-miR-281-1*; dme-miR-281-1*.
XX
CC miR-281 was reported independently in references [1] and [2]. The
CC sequence in this entry is from reference [2] which identified a 23 nt
CC excised sequence from the 3' arm of the precursor by cloning. Reference
CC [1] reported the reverse complement of this foldback precursor from
CC computational prediction and northern blotting. The predicted mature
CC sequence (5' and 3' ends unknown) from the 3' arm of the reverse
CC complement was named miR-281a in reference [1] and is designated
CC miR-281-1* here.
XX
FH Key Location/Qualifiers
FH
FT miRNA 14..36
FT /accession="MIMAT0000344"
FT /product="dme-miR-281-1-5p"
FT /evidence=experimental
FT /experiment="Northern [1], 454 [3-4], Illumina [4]"
FT /similarity="MI0000366"
FT miRNA 58..80
FT /accession="MIMAT0000345"
FT /product="dme-miR-281-3p"
FT /evidence=experimental
FT /experiment="Northern [1], cloned [2], 454 [3-4], Illumina
FT [4]"
FT /similarity="MI0000366"
XX
SQ Sequence 90 BP; 29 A; 16 C; 17 G; 0 T; 28 other;
cgaauaagug aauaaagaga gcuguccguc gacaguccag aaacuauuua auaucacugu 60
cauggaauug cucucuuugu auaauauucg 90
//
ID dme-mir-282 standard; RNA; DME; 97 BP.
XX
AC MI0000367;
XX
DE Drosophila melanogaster miR-282 stem-loop
XX
RN [1]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [2]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [3]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-282; miR-282.
DR TARGETS:PICTAR-FLY; dme-miR-282; dme-miR-282.
XX
FH Key Location/Qualifiers
FH
FT miRNA 17..40
FT /accession="MIMAT0000346"
FT /product="dme-miR-282-5p"
FT /evidence=experimental
FT /experiment="Northern [1], 454 [2-3], Illumina [3]"
FT /similarity="MI0000367"
FT miRNA 60..81
FT /accession="MIMAT0020809"
FT /product="dme-miR-282-3p"
FT /evidence=not_experimental
XX
SQ Sequence 97 BP; 27 A; 22 C; 21 G; 0 T; 27 other;
aguuuccuuc uaaaucuagc cucuacuagg cuuugucugu gcauucgaaa gccgaucaga 60
cauagccuau aagagguuag guguaccaag gcgaaca 97
//
ID dme-mir-283 standard; RNA; DME; 100 BP.
XX
AC MI0000368;
XX
DE Drosophila melanogaster miR-283 stem-loop
XX
RN [1]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [2]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [3]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [4]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-283; miR-283.
DR TARGETS:PICTAR-FLY; dme-miR-283; dme-miR-283.
XX
FH Key Location/Qualifiers
FH
FT miRNA 21..42
FT /accession="MIMAT0000347"
FT /product="dme-miR-283-5p"
FT /evidence=experimental
FT /experiment="Northern [1-2], 454 [3-4], Illumina [4]"
FT /similarity="MI0000368"
FT miRNA 68..88
FT /accession="MIMAT0020810"
FT /product="dme-miR-283-3p"
FT /evidence=not_experimental
XX
SQ Sequence 100 BP; 31 A; 18 C; 19 G; 0 T; 32 other;
cucacacgau ucucaaaggu aaauaucagc ugguaauucu gggagcuaag ccuaaauaug 60
aaacacucgg aauuucaguu gguaucgacu uuuuugaauu 100
//
ID dme-mir-284 standard; RNA; DME; 100 BP.
XX
AC MI0000369;
XX
DE Drosophila melanogaster miR-284 stem-loop
XX
RN [1]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [2]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [3]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-284; miR-284.
DR TARGETS:PICTAR-FLY; dme-miR-284; dme-miR-284.
XX
FH Key Location/Qualifiers
FH
FT miRNA 10..35
FT /accession="MIMAT0020811"
FT /product="dme-miR-284-5p"
FT /evidence=not_experimental
FT miRNA 68..88
FT /accession="MIMAT0000348"
FT /product="dme-miR-284-3p"
FT /evidence=experimental
FT /experiment="Northern [1], 454 [2-3], Illumina [3]"
FT /similarity="MI0000369"
XX
SQ Sequence 100 BP; 24 A; 21 C; 28 G; 0 T; 27 other;
guugcaguuc cuggaauuaa guugacugug uagccuguga gggcaaggcu ugaauaaugc 60
uccugaaguc agcaacuuga uuccagcaau ugcggcccga 100
//
ID dme-mir-281-2 standard; RNA; DME; 92 BP.
XX
AC MI0000370;
XX
DE Drosophila melanogaster miR-281-2 stem-loop
XX
RN [1]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [2]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [3]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [4]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-281bS; miR-281bS.
DR TARGETS:PICTAR-FLY; dme-miR-281; dme-miR-281.
DR TARGETS:PICTAR-FLY; dme-miR-281-2*; dme-miR-281-2*.
XX
CC miR-281 was reported independently in references [1] and [2]. The
CC sequence in this entry is from reference [2] which identified a 23 nt
CC excised sequence from the 3' arm of the precursor by cloning. Reference
CC [1] reported the reverse complement of this foldback precursor from
CC computational prediction and northern blotting. The predicted mature
CC sequence (5' and 3' ends unknown) from the 3' arm of the reverse
CC complement was named miR-281b in reference [1] and is designated
CC miR-281-2* here.
XX
FH Key Location/Qualifiers
FH
FT miRNA 15..36
FT /accession="MIMAT0000349"
FT /product="dme-miR-281-2-5p"
FT /evidence=experimental
FT /experiment="Northern [1], 454 [3-4], Illumina [4]"
FT /similarity="MI0000370"
FT miRNA 60..82
FT /accession="MIMAT0000345"
FT /product="dme-miR-281-3p"
FT /evidence=experimental
FT /experiment="Northern [1], cloned [2], 454 [3-4], Illumina
FT [4]"
FT /similarity="MI0000370"
XX
SQ Sequence 92 BP; 28 A; 16 C; 20 G; 0 T; 28 other;
cgaauuguga aaugaagaga gcuauccguc gacagucaag uuaagaccga uuguaauacu 60
gucauggaau ugcucucuuu guauaacauu cg 92
//
ID dme-mir-34 standard; RNA; DME; 99 BP.
XX
AC MI0000371;
XX
DE Drosophila melanogaster miR-34 stem-loop
XX
RN [1]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [2]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [3]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [4]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [5]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-34; miR-34.
DR TARGETS:PICTAR-FLY; dme-miR-34; dme-miR-34.
XX
CC This sequence is computationally predicted based on conservation in D.
CC pseudoobscura and C. elegans. The precise 5' or 3' ends are unknown.
CC Expression in D. melanogaster was confirmed by Northern blot analysis [1].
CC Aravin et al. later identify the 5' and 3' ends by cloning [3].
XX
FH Key Location/Qualifiers
FH
FT miRNA 17..40
FT /accession="MIMAT0000350"
FT /product="dme-miR-34-5p"
FT /evidence=experimental
FT /experiment="Northern [1], cloned [3], 454 [4-5], Illumina
FT [5]"
FT /similarity="MI0000371"
FT miRNA 68..90
FT /accession="MIMAT0020812"
FT /product="dme-miR-34-3p"
FT /evidence=not_experimental
XX
SQ Sequence 99 BP; 20 A; 25 C; 25 G; 0 T; 29 other;
aauuggcuau gcgcuuuggc agugugguua gcugguugug uagccaauua uugccguuga 60
caauucacag ccacuaucuu cacugccgcc gcgacaagc 99
//
ID dme-mir-124 standard; RNA; DME; 100 BP.
XX
AC MI0000373;
XX
DE Drosophila melanogaster miR-124 stem-loop
XX
RN [1]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [2]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [3]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [4]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [5]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-124; miR-124.
DR TARGETS:PICTAR-FLY; dme-miR-124; dme-miR-124.
XX
CC miR-124 was reported independently in references [1] and [2].
CC Computational prediction followed by northern blotting confirmed that the
CC strand containing the predicted miR is predominantly expressed [1].
CC Reference [2] confirmed the 5' end of the excised miRNA by cloning and
CC reported a length distribution of 19-23 nt with 23 nt the most commonly
CC expressed.
XX
FH Key Location/Qualifiers
FH
FT miRNA 23..45
FT /accession="MIMAT0020813"
FT /product="dme-miR-124-5p"
FT /evidence=not_experimental
FT miRNA 57..79
FT /accession="MIMAT0000351"
FT /product="dme-miR-124-3p"
FT /evidence=experimental
FT /experiment="cloned [2], Northern [2-3], 454 [4-5],
FT Illumina [5]"
FT /similarity="MI0000373"
XX
SQ Sequence 100 BP; 25 A; 24 C; 21 G; 0 T; 30 other;
ucauuuggua cguuuuucuc cugguaucca cuguaggccu auauguauuu ccaccauaag 60
gcacgcggug aaugccaaga gcgaacgcag uucuacaaau 100
//
ID dme-mir-79 standard; RNA; DME; 97 BP.
XX
AC MI0000374;
XX
DE Drosophila melanogaster miR-79 stem-loop
XX
RN [1]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [2]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [3]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [4]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [5]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-79; miR-79.
DR TARGETS:PICTAR-FLY; dme-miR-79; dme-miR-79.
XX
CC miR-79 was reported independently by three groups using computational
CC prediction [2], Northern blot analysis [1] and cloning [3]. References
CC [1] and [2] confirmed that the strand containing the predicted miR is
CC predominantly expressed [1]. Reference [3] confirmed the ends of the
CC excised miRNA by cloning.
XX
FH Key Location/Qualifiers
FH
FT miRNA 19..41
FT /accession="MIMAT0020814"
FT /product="dme-miR-79-5p"
FT /evidence=not_experimental
FT miRNA 60..81
FT /accession="MIMAT0000352"
FT /product="dme-miR-79-3p"
FT /evidence=experimental
FT /experiment="Northern [1], cloned [3], 454 [4-5], Illumina
FT [5]"
FT /similarity="MI0000374"
XX
SQ Sequence 97 BP; 26 A; 19 C; 20 G; 0 T; 32 other;
ugaagcugac uugccauugc uuuggcgcuu uagcuguaug auagauuuaa acuacuucau 60
aaagcuagau uaccaaagca uuggcuucug cagguca 97
//
ID dme-mir-276b standard; RNA; DME; 99 BP.
XX
AC MI0000375;
XX
DE Drosophila melanogaster miR-276b stem-loop
XX
RN [1]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [2]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [3]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [4]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-276b; miR-276b.
DR TARGETS:PICTAR-FLY; dme-miR-276b; dme-miR-276b.
XX
FH Key Location/Qualifiers
FH
FT miRNA 23..45
FT /accession="MIMAT0020815"
FT /product="dme-miR-276b-5p"
FT /evidence=experimental
FT /experiment="Northern [1], 454 [3-4], Illumina [4]"
FT /similarity="MI0000375"
FT miRNA 62..83
FT /accession="MIMAT0000354"
FT /product="dme-miR-276b-3p"
FT /evidence=experimental
FT /experiment="Northern [1], cloned [2], 454 [3-4], Illumina
FT [4]"
FT /similarity="MI0000375"
XX
SQ Sequence 99 BP; 26 A; 23 C; 21 G; 0 T; 29 other;
aaaaccgaag ucuuuuuacc aucagcgagg uauagaguuc cuacguuccu auauucaguc 60
guaggaacuu aauaccgugc ucuuggagga cugucgacc 99
//
ID dme-mir-210 standard; RNA; DME; 100 BP.
XX
AC MI0000376;
XX
DE Drosophila melanogaster miR-210 stem-loop
XX
RN [1]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [2]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [3]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [4]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-210; miR-210.
DR TARGETS:PICTAR-FLY; dme-miR-210; dme-miR-210.
XX
CC This sequence is computationally predicted based on conservation in D.
CC pseudoobscura. The precise 5' or 3' ends are unknown. Northern blotting
CC confirmed that the strand containing the predicted miR is predominantly
CC expressed.
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..38
FT /accession="MIMAT0020816"
FT /product="dme-miR-210-5p"
FT /evidence=not_experimental
FT miRNA 52..74
FT /accession="MIMAT0000355"
FT /product="dme-miR-210-3p"
FT /evidence=experimental
FT /experiment="cloned [2], 454 [3-4], Illumina [4]"
FT /similarity="MI0000376"
XX
SQ Sequence 100 BP; 28 A; 22 C; 27 G; 0 T; 23 other;
aaaggugcuu auugcagcug cuggccacug cacaagauua gacuuaagac ucuugugcgu 60
gugacagcgg cuauuguaag aggccauaga agcaacagcc 100
//
ID dme-mir-285 standard; RNA; DME; 99 BP.
XX
AC MI0000377;
XX
DE Drosophila melanogaster miR-285 stem-loop
XX
RN [1]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [2]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [3]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [4]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-285; miR-285.
DR TARGETS:PICTAR-FLY; dme-miR-285; dme-miR-285.
XX
CC miR-285 was reported independently in references [1] and [2].
CC Computational prediction followed by northern blotting confirmed that the
CC strand containing the predicted miR is predominantly expressed [1].
CC Reference [2] confirmed the ends of the excised miRNA by cloning.
XX
FH Key Location/Qualifiers
FH
FT miRNA 13..35
FT /accession="MIMAT0020817"
FT /product="dme-miR-285-5p"
FT /evidence=not_experimental
FT miRNA 64..85
FT /accession="MIMAT0000356"
FT /product="dme-miR-285-3p"
FT /evidence=experimental
FT /experiment="cloned [2], 454 [3], Illumina [4]"
FT /similarity="MI0000377"
XX
SQ Sequence 99 BP; 35 A; 20 C; 19 G; 0 T; 25 other;
ucgaaucgaa gaacugagau cgauuggugc auagauauca ggagaaccca cucaauuuaa 60
cucuagcacc auucgaaauc agugcuuuug auaagaaac 99
//
ID dme-mir-100 standard; RNA; DME; 100 BP.
XX
AC MI0000378;
XX
DE Drosophila melanogaster miR-100 stem-loop
XX
RN [1]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [2]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [3]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [4]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [5]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-100; miR-100.
DR TARGETS:PICTAR-FLY; dme-miR-100; dme-miR-100.
XX
CC miR-100 was reported independently by three groups using computational
CC prediction [2], Northern blot analysis [1] and cloning [3]. References
CC [1] and [2] confirmed that the strand containing the predicted miR is
CC predominantly expressed [1]. Reference [3] confirmed the ends of the
CC excised miRNA by cloning.
XX
FH Key Location/Qualifiers
FH
FT miRNA 12..33
FT /accession="MIMAT0000357"
FT /product="dme-miR-100-5p"
FT /evidence=experimental
FT /experiment="Northern [1,3], 454 [4-5], Illumina [5]"
FT /similarity="MI0000378"
FT miRNA 51..72
FT /accession="MIMAT0020818"
FT /product="dme-miR-100-3p"
FT /evidence=not_experimental
XX
SQ Sequence 100 BP; 29 A; 21 C; 20 G; 0 T; 30 other;
ccauuaacag aaacccguaa auccgaacuu gugcuguuuu auaucuguua caagaccggc 60
auuaugggag ucugucaaug caaacaacug guuuuuggca 100
//
ID dme-mir-92b standard; RNA; DME; 100 BP.
XX
AC MI0000379;
XX
DE Drosophila melanogaster miR-92b stem-loop
XX
RN [1]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [2]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [3]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [4]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [5]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-92b; miR-92b.
DR TARGETS:PICTAR-FLY; dme-miR-92b; dme-miR-92b.
XX
CC miR-92b was reported independently in references [1] and [2].
CC Computational prediction followed by northern blotting confirmed that the
CC strand containing the predicted miR is predominantly expressed [1].
CC Reference [2] confirmed the ends of the excised miRNA by cloning.
XX
FH Key Location/Qualifiers
FH
FT miRNA 19..41
FT /accession="MIMAT0020819"
FT /product="dme-miR-92b-5p"
FT /evidence=not_experimental
FT miRNA 60..81
FT /accession="MIMAT0000358"
FT /product="dme-miR-92b-3p"
FT /evidence=experimental
FT /experiment="Northern [1,3], cloned [2], 454 [4-5],
FT Illumina [5]"
FT /similarity="MI0000379"
XX
SQ Sequence 100 BP; 24 A; 25 C; 23 G; 0 T; 28 other;
uaaaacguca ccugauguag gccgugccca gugcuuauuu guugcauuuu cgaaauacaa 60
auugcacuag ucccggccug caaugagugu cgcagucgac 100
//
ID dme-mir-286 standard; RNA; DME; 100 BP.
XX
AC MI0000380;
XX
DE Drosophila melanogaster miR-286 stem-loop
XX
RN [1]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [2]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [3]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [4]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-286; miR-286.
DR TARGETS:PICTAR-FLY; dme-miR-286; dme-miR-286.
XX
CC miR-286 was reported independently in references [1] and [2].
CC Computational prediction followed by northern blotting confirmed that the
CC strand containing the predicted miR is predominantly expressed [1].
CC Reference [2] confirmed the 5' end of the excised miRNA by cloning and
CC reported a length distribution of 22-24 nt with 23 nt the most commonly
CC expressed.
XX
FH Key Location/Qualifiers
FH
FT miRNA 13..34
FT /accession="MIMAT0020820"
FT /product="dme-miR-286-5p"
FT /evidence=not_experimental
FT miRNA 65..87
FT /accession="MIMAT0000359"
FT /product="dme-miR-286-3p"
FT /evidence=experimental
FT /experiment="Northern [1], cloned [2], 454 [3-4], Illumina
FT [4]"
FT /similarity="MI0000380"
XX
SQ Sequence 100 BP; 33 A; 14 C; 21 G; 0 T; 32 other;
uuaaaauuga auggcgaaug ucgguauggu cucuuuuuca aagaaagguu ucgauuaagc 60
gaagugacua gaccgaacac ucgugcuaua auuuuaaaau 100
//
ID dme-mir-287 standard; RNA; DME; 93 BP.
XX
AC MI0000381;
XX
DE Drosophila melanogaster miR-287 stem-loop
XX
RN [1]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
DR TARGETS:MIRTE; miR-287; miR-287.
DR TARGETS:PICTAR-FLY; dme-miR-287; dme-miR-287.
XX
CC This sequence is computationally predicted based on conservation in D.
CC pseudoobscura. The precise 5' or 3' ends are unknown. Northern blotting
CC confirmed that the strand containing the predicted miR is predominantly
CC expressed.
XX
FH Key Location/Qualifiers
FH
FT miRNA 65..85
FT /accession="MIMAT0000360"
FT /product="dme-miR-287-3p"
FT /evidence=experimental
FT /experiment="Northern [1]"
FT /similarity="MI0000381"
XX
SQ Sequence 93 BP; 25 A; 12 C; 27 G; 0 T; 29 other;
ggacgccggg gauguauggg uguguagggu cugaaauuuu gcacacauuu acaauaauug 60
uaaauguguu gaaaaucguu ugcacgacug uga 93
//
ID dme-mir-87 standard; RNA; DME; 99 BP.
XX
AC MI0000382;
XX
DE Drosophila melanogaster miR-87 stem-loop
XX
RN [1]
RX PUBMED; 12812784.
RA Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V;
RT "Temporal regulation of microRNA expression in Drosophila melanogaster
RT mediated by hormonal signals and broad-Complex gene activity";
RL Dev Biol. 259:9-18(2003).
XX
RN [2]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [3]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [4]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [5]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-87; miR-87.
DR TARGETS:PICTAR-FLY; dme-miR-87; dme-miR-87.
XX
FH Key Location/Qualifiers
FH
FT miRNA 13..34
FT /accession="MIMAT0020821"
FT /product="dme-miR-87-5p"
FT /evidence=not_experimental
FT miRNA 61..84
FT /accession="MIMAT0000361"
FT /product="dme-miR-87-3p"
FT /evidence=experimental
FT /experiment="Northern [1-2], 454 [4-5], Illumina [5]"
FT /similarity="MI0000382"
XX
SQ Sequence 99 BP; 25 A; 22 C; 23 G; 0 T; 29 other;
aacacauuuc auucgcgccu guaucuugcu gaaccgcugc cauuauggcc aacgauccgg 60
uugagcaaaa uuucaggugu gugagaaaug uguuuagca 99
//
ID dme-mir-263b standard; RNA; DME; 90 BP.
XX
AC MI0000383;
XX
DE Drosophila melanogaster miR-263b stem-loop
XX
RN [1]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [2]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [3]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [4]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
DR TARGETS:MIRTE; miR-263b; miR-263b.
DR TARGETS:PICTAR-FLY; dme-miR-263b; dme-miR-263b.
XX
CC miR-263b was reported independently in references [1] and [2].
CC Computational prediction followed by northern blotting confirmed that the
CC strand containing the predicted miR is predominantly expressed [1].
CC Reference [2] confirmed the ends of the excised miRNA by cloning.
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..36
FT /accession="MIMAT0000362"
FT /product="dme-miR-263b-5p"
FT /evidence=experimental
FT /experiment="cloned [2], 454 [3-4], Illumina [4]"
FT /similarity="MI0000383"
FT miRNA 55..76
FT /accession="MIMAT0020822"
FT /product="dme-miR-263b-3p"
FT /evidence=not_experimental
XX
SQ Sequence 90 BP; 20 A; 17 C; 22 G; 0 T; 31 other;
uugcugacuu ugagucuugg cacugggaga auucacaguu gacuuuauua uucugugguu 60
cugcgggugc caaaacuuaa aaaccggcuu 90
//
ID dme-mir-288 standard; RNA; DME; 97 BP.
XX
AC MI0000384;
XX
DE Drosophila melanogaster miR-288 stem-loop
XX
RN [1]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
DR TARGETS:MIRTE; miR-288; miR-288.
DR TARGETS:PICTAR-FLY; dme-miR-288; dme-miR-288.
XX
CC This sequence is computationally predicted based on conservation in D.
CC pseudoobscura. The precise 5' or 3' ends are unknown. Northern blotting
CC confirmed that the strand containing the predicted miR is predominantly
CC expressed.
XX
FH Key Location/Qualifiers
FH
FT miRNA 66..88
FT /accession="MIMAT0000363"
FT /product="dme-miR-288-3p"
FT /evidence=experimental
FT /experiment="Northern [1]"
FT /similarity="MI0000384"
XX
SQ Sequence 97 BP; 20 A; 23 C; 28 G; 0 T; 26 other;
cggccauguc guaauuagcg gagcacggca ucgccggcga uaauuaauga cgguggucac 60
guugguuuca ugucgauuuc auuucaugac acggccg 97
//
ID dme-mir-289 standard; RNA; DME; 99 BP.
XX
AC MI0000385;
XX
DE Drosophila melanogaster miR-289 stem-loop
XX
RN [1]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
DR TARGETS:MIRTE; miR-289; miR-289.
DR TARGETS:PICTAR-FLY; dme-miR-289; dme-miR-289.
XX
CC This sequence is computationally predicted based on conservation in D.
CC pseudoobscura. The precise 5' or 3' ends are unknown. Northern blotting
CC confirmed that the strand containing the predicted miR is predominantly
CC expressed.
XX
FH Key Location/Qualifiers
FH
FT miRNA 16..41
FT /accession="MIMAT0000364"
FT /product="dme-miR-289-5p"
FT /evidence=experimental
FT /experiment="Northern [1]"
FT /similarity="MI0000385"
XX
SQ Sequence 99 BP; 28 A; 18 C; 25 G; 0 T; 28 other;
gaguuuacag uaaaauaaau auuuaagugg agccugcgac uucagucccu cugacugacu 60
gggguaaguc acuugagcgu uuguuggcac guaaaagac 99
//
ID dme-bantam standard; RNA; DME; 81 BP.
XX
AC MI0000387;
XX
DE Drosophila melanogaster bantam stem-loop
XX
RN [1]
RX PUBMED; 12679032.
RA Brennecke J, Hipfner DR, Stark A, Russell RB, Cohen SM;
RT "bantam encodes a developmentally regulated microRNA that controls cell
RT proliferation and regulates the proapoptotic gene hid in Drosophila";
RL Cell. 113:25-36(2003).
XX
RN [2]
RX PUBMED; 12844358.
RA Lai EC, Tomancak P, Williams RW, Rubin GM;
RT "Computational identification of Drosophila microRNA genes";
RL Genome Biol. 4:R42(2003).
XX
RN [3]
RX PUBMED; 12919683.
RA Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B,
RA Gaasterland T, Meyer J, Tuschl T;
RT "The small RNA profile during Drosophila melanogaster development";
RL Dev Cell. 5:337-350(2003).
XX
RN [4]
RX PUBMED; 12946623.
RA Moberg KH, Hariharan IK;
RT "Big things from a little RNA";
RL Trends Cell Biol. 13:455-457(2003).
XX
RN [5]
RX PUBMED; 17989254.
RA Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC;
RT "Evolution, biogenesis, expression, and target predictions of a
RT substantially expanded set of Drosophila microRNAs";
RL Genome Res. 17:1850-1864(2007).
XX
RN [6]
RX PUBMED; 17989255.
RA Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis
RA M;
RT "Systematic discovery and characterization of fly microRNAs using 12
RT Drosophila genomes";
RL Genome Res. 17:1865-1879(2007).
XX
CC bantam microRNA was predicted independently by two groups using
CC computational approaches [1,2]. Northern blotting confirmed that the
CC strand containing the predicted miR is predominantly expressed. Subsequent
CC cloning studies have independently identified the same miRNA and confirmed
CC the 5' end [3]. A length distribution of 20-23 nt was reported with a 23
CC nt sequence the most commonly expressed. bantam is reported to promote
CC tissue growth [1]. bantam expression is temporally and spatially
CC regulated in response to patterning cues. bantam microRNA simultaneously
CC stimulates cell proliferation and prevents apoptosis and is predicted to
CC target the pro-apoptotic gene hid [1].
XX
FH Key Location/Qualifiers
FH
FT miRNA 15..37
FT /accession="MIMAT0020823"
FT /product="dme-bantam-5p"
FT /evidence=not_experimental
FT miRNA 52..74
FT /accession="MIMAT0000365"
FT /product="dme-bantam-3p"
FT /evidence=experimental
FT /experiment="Northern [1], cloned [3], 454 [5-6], Illumina
FT [6]"
FT /similarity="MI0000387"
XX
SQ Sequence 81 BP; 21 A; 11 C; 16 G; 0 T; 33 other;
auuugacuac gaaaccgguu uucgauuugg uuugacuguu uuucauacaa gugagaucau 60
uuugaaagcu gauuuuguca a 81
//
ID mmu-mir-290a standard; RNA; MMU; 83 BP.
XX
AC MI0000388;
XX
DE Mus musculus miR-290a stem-loop
XX
RN [1]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 3711323; Mir290.
DR ENTREZGENE; 100049710; Mir290.
XX
FH Key Location/Qualifiers
FH
FT miRNA 14..35
FT /accession="MIMAT0000366"
FT /product="mmu-miR-290a-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1], Illumina [3-4]"
FT miRNA 49..72
FT /accession="MIMAT0004572"
FT /product="mmu-miR-290a-3p"
FT /evidence=experimental
FT /experiment="cloned [2], Illumina [3-4]"
XX
SQ Sequence 83 BP; 16 A; 20 C; 18 G; 0 T; 29 other;
cucaucuugc gguacucaaa cuaugggggc acuuuuuuuu uucuuuaaaa agugccgccu 60
aguuuuaagc cccgccgguu gag 83
//
ID mmu-mir-291a standard; RNA; MMU; 82 BP.
XX
AC MI0000389;
XX
DE Mus musculus miR-291a stem-loop
XX
RN [1]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 3711324; Mir291a.
DR ENTREZGENE; 100049715; Mir291a.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 14..35
FT /accession="MIMAT0000367"
FT /product="mmu-miR-291a-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Illumina [3-4]"
FT miRNA 50..71
FT /accession="MIMAT0000368"
FT /product="mmu-miR-291a-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1], Illumina [3-4]"
XX
SQ Sequence 82 BP; 17 A; 21 C; 23 G; 0 T; 21 other;
ccuauguagc ggccaucaaa guggaggccc ucucuugagc cugaaugaga aagugcuucc 60
acuuugugug ccacugcaug gg 82
//
ID mmu-mir-292a standard; RNA; MMU; 82 BP.
XX
AC MI0000390;
XX
DE Mus musculus miR-292 stem-loop
XX
RN [1]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 3711325; Mir292.
DR ENTREZGENE; 100049711; Mir292.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [2]. The 5' end of the miRNA may be
CC offset with respect to previous annotations.
XX
FH Key Location/Qualifiers
FH
FT miRNA 12..33
FT /accession="MIMAT0000369"
FT /product="mmu-miR-292a-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1], Illumina [3-4]"
FT miRNA 50..73
FT /accession="MIMAT0000370"
FT /product="mmu-miR-292a-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1], Illumina [3-4]"
XX
SQ Sequence 82 BP; 17 A; 17 C; 24 G; 0 T; 24 other;
cagccuguga uacucaaacu gggggcucuu uuggauuuuc aucggaagaa aagugccgcc 60
agguuuugag ugucaccggu ug 82
//
ID mmu-mir-293 standard; RNA; MMU; 80 BP.
XX
AC MI0000391;
XX
DE Mus musculus miR-293 stem-loop
XX
RN [1]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 3711326; Mir293.
DR ENTREZGENE; 100049714; Mir293.
XX
FH Key Location/Qualifiers
FH
FT miRNA 14..35
FT /accession="MIMAT0004573"
FT /product="mmu-miR-293-5p"
FT /evidence=experimental
FT /experiment="cloned [2], Illumina [3-4]"
FT miRNA 48..69
FT /accession="MIMAT0000371"
FT /product="mmu-miR-293-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1], Illumina [3-4]"
XX
SQ Sequence 80 BP; 17 A; 12 C; 21 G; 0 T; 30 other;
uucaaucugu gguacucaaa cugugugaca uuuuguucuu uguaagaagu gccgcagagu 60
uuguaguguu gccgauugag 80
//
ID mmu-mir-294 standard; RNA; MMU; 84 BP.
XX
AC MI0000392;
XX
DE Mus musculus miR-294 stem-loop
XX
RN [1]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 3711327; Mir294.
DR ENTREZGENE; 100049712; Mir294.
XX
FH Key Location/Qualifiers
FH
FT miRNA 15..36
FT /accession="MIMAT0004574"
FT /product="mmu-miR-294-5p"
FT /evidence=experimental
FT /experiment="cloned [2], Illumina [3-4]"
FT miRNA 51..72
FT /accession="MIMAT0000372"
FT /product="mmu-miR-294-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1], Illumina [3-4]"
XX
SQ Sequence 84 BP; 20 A; 17 C; 19 G; 0 T; 28 other;
uuccauauag ccauacucaa aauggaggcc cuaucuaagc uuuuaagugg aaagugcuuc 60
ccuuuugugu guugccaugu ggag 84
//
ID mmu-mir-295 standard; RNA; MMU; 69 BP.
XX
AC MI0000393;
XX
DE Mus musculus miR-295 stem-loop
XX
RN [1]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 3711328; Mir295.
DR ENTREZGENE; 100049713; Mir295.
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..28
FT /accession="MIMAT0004575"
FT /product="mmu-miR-295-5p"
FT /evidence=experimental
FT /experiment="cloned [2], Illumina [3-4]"
FT miRNA 43..65
FT /accession="MIMAT0000373"
FT /product="mmu-miR-295-3p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1], Illumina [3-4]"
XX
SQ Sequence 69 BP; 17 A; 15 C; 17 G; 0 T; 20 other;
ggugagacuc aaaugugggg cacacuucug gacuguacau agaaagugcu acuacuuuug 60
agucucucc 69
//
ID mmu-mir-296 standard; RNA; MMU; 79 BP.
XX
AC MI0000394;
XX
DE Mus musculus miR-296 stem-loop
XX
RN [1]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 3619269; Mir296.
DR ENTREZGENE; 723906; Mir296.
XX
FH Key Location/Qualifiers
FH
FT miRNA 13..33
FT /accession="MIMAT0000374"
FT /product="mmu-miR-296-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1], Illumina [3-4]"
FT miRNA 47..68
FT /accession="MIMAT0004576"
FT /product="mmu-miR-296-3p"
FT /evidence=experimental
FT /experiment="cloned [2], Illumina [3-4]"
XX
SQ Sequence 79 BP; 8 A; 23 C; 27 G; 0 T; 21 other;
gggccuuucu ggagggcccc cccucaaucc uguugugcuc gcuucagagg guugggugga 60
ggcucuccug aaggugucc 79
//
ID mmu-mir-297a-1 standard; RNA; MMU; 76 BP.
XX
AC MI0000395;
XX
DE Mus musculus miR-297a-1 stem-loop
XX
RN [1]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
DR MGI; 3619319; Mirn297-1.
DR ENTREZGENE; 723831; Mir297-1.
XX
CC Houbaviy et al. report that the cloned sequence of miR-297 is found over
CC 20 times in the mouse genomic sequence [1]. This sequence appears to
CC match several low complexity repetitive regions. Confidence in which loci
CC actually express miR-297 is low because of the low complexity nature of
CC the sequence. The mature sequence shown here represents the most commonly
CC cloned form from large-scale cloning studies [2]. The ends of the miRNA
CC may be offset with respect to previous annotations.
XX
FH Key Location/Qualifiers
FH
FT miRNA 15..36
FT /accession="MIMAT0000375"
FT /product="mmu-miR-297a-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Northern [1]"
XX
SQ Sequence 76 BP; 20 A; 7 C; 17 G; 0 T; 32 other;
auauguaugu auguauguau gugugcaugu gcaugugcau guaugcauau ugcauguaua 60
uauuaugcau acaugu 76
//
ID mmu-mir-297a-2 standard; RNA; MMU; 90 BP.
XX
AC MI0000397;
XX
DE Mus musculus miR-297a-2 stem-loop
XX
RN [1]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
DR MGI; 3619320; Mirn297-2.
DR ENTREZGENE; 723945; Mir297-2.
XX
CC Houbaviy et al. report that the cloned sequence of miR-297 is found over
CC 20 times in the mouse genomic sequence [1]. This sequence appears to
CC match several low complexity repetitive regions. Confidence in which loci
CC actually express miR-297 is low because of the low complexity nature of
CC the sequence.
XX
FH Key Location/Qualifiers
FH
FT miRNA 11..32
FT /accession="MIMAT0000375"
FT /product="mmu-miR-297a-5p"
FT /evidence=experimental
FT /experiment="cloned [1], Northern [1]"
XX
SQ Sequence 90 BP; 28 A; 19 C; 17 G; 0 T; 26 other;
cuguguguau auguaugugu gcaugugcau guguguauau gaguauacau auacauacgc 60
acauacccau acaagcaugc acacaaaccc 90
//
ID mmu-mir-298 standard; RNA; MMU; 82 BP.
XX
AC MI0000398;
XX
DE Mus musculus miR-298 stem-loop
XX
RN [1]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 3619321; Mir298.
DR ENTREZGENE; 723832; Mir298.
XX
CC The mature sequence shown here represents the most commonly cloned form
CC from large-scale cloning studies [2].
XX
FH Key Location/Qualifiers
FH
FT miRNA 11..33
FT /accession="MIMAT0000376"
FT /product="mmu-miR-298-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Illumina [3-4]"
FT miRNA 51..74
FT /accession="MIMAT0017007"
FT /product="mmu-miR-298-3p"
FT /evidence=experimental
FT /experiment="Illumina [4]"
XX
SQ Sequence 82 BP; 14 A; 18 C; 26 G; 0 T; 24 other;
ccaggccuuu ggcagaggag ggcuguucuu cccuugaguu uuaugacugg gaggaacuag 60
ccuucucuca gcuuaggagu gg 82
//
ID mmu-mir-299a standard; RNA; MMU; 63 BP.
XX
AC MI0000399;
XX
DE Mus musculus miR-299 stem-loop
XX
RN [1]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newborn mouse ovaries determined by massive
RT parallel sequencing";
RL Mol Hum Reprod. 16:463-471(2010).
XX
RN [4]
RX PUBMED; 20413612.
RA Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston
RA WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel
RA DP;
RT "Mammalian microRNAs: experimental evaluation of novel and previously
RT annotated genes";
RL Genes Dev. 24:992-1009(2010).
XX
DR MGI; 3619322; Mir299.
DR ENTREZGENE; 723927; Mir299.
XX
FH Key Location/Qualifiers
FH
FT miRNA 7..28
FT /accession="MIMAT0000377"
FT /product="mmu-miR-299a-5p"
FT /evidence=experimental
FT /experiment="cloned [1-2], Illumina [3-4]"
FT miRNA 39..60
FT /accession="MIMAT0004577"
FT /product="mmu-miR-299a-3p"
FT /evidence=experimental
FT /experiment="cloned [2], Illumina [3-4]"
XX
SQ Sequence 63 BP; 17 A; 12 C; 14 G; 0 T; 20 other;
aagaaauggu uuaccguccc acauacauuu ugaguaugua ugugggacgg uaaaccgcuu 60
cuu 63
//
ID mmu-mir-300 standard; RNA; MMU; 79 BP.
XX
AC MI0000400;
XX
DE Mus musculus miR-300 stem-loop
XX
RN [1]
RX PUBMED; 12919684.
RA Houbaviy HB, Murray MF, Sharp PA;
RT "Embryonic stem cell-specific MicroRNAs";
RL Dev Cell. 5:351-358(2003).
XX
RN [2]
RX PUBMED; 17604727.
RA Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S,
RA Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V,
RA Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B,
RA Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G,
RA Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di
RA Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN,
RA Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo
RA JJ, Sander C, Zavolan M, Tuschl T;
RT "A mammalian microRNA expression atlas based on small RNA library
RT sequencing";
RL Cell. 129:1401-1414(2007).
XX
RN [3]
RX PUBMED; 20215419.
RA Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A,
RA Marra MA, Rajkovic A;
RT "MicroRNA transcriptome in the newb