miRBase entry: cel-mir-56

Stem-loop cel-mir-56


Accession
MI0000027
Description
Caenorhabditis elegans cel-mir-56 precursor miRNA
Gene family
MIPF0001735; mir-56

Literature search
5 open access papers mention cel-mir-56
(7 sentences)

Sequence

476769 reads, 3018 reads per million, 16 experiments
gagccagugucuguucuUGGCGGAUCCAUUUUGGGUUGUACCucauccuaaauuugacggUACCCGUAAUGUUUCCGCUGAGaaccgacugugcacc
..((((((....((((((((((((..((((.(((((...((((((.........))).)))))))).))))..))))))))))))..)))).))...

Structure
-ga  -    gucu            UC    U     UGU   -   ucc 
   gc cagu    guucuUGGCGGA  CAUU UGGGU   ACC uca   u
   || ||||    ||||||||||||  |||| |||||   ||| |||   a
   cg guca    caaGAGUCGCCU  GUAA GCCCA   Ugg agu   a
cca  u    --gc            UU    U     ---   c   uua 


Annotation confidence High
Do you think this miRNA is real?

Genome context
chrX: 13144691-13144787 [-]
Clustered miRNAs
3 other miRNAs are < 10 kb from cel-mir-56
Name Accession Chromosome Start End Strand Confidence




Database links

Mature cel-miR-56-5p

Accession MIMAT0000027
Description Caenorhabditis elegans cel-miR-56-5p mature miRNA
Sequence 18 - UGGCGGAUCCAUUUUGGGUUGUACC - 42
Evidence experimental
cloned [1], CLIPseq [7]
Database links

Mature cel-miR-56-3p

Accession MIMAT0000028
Description Caenorhabditis elegans cel-miR-56-3p mature miRNA
Sequence 61 - UACCCGUAAUGUUUCCGCUGAG - 82
Evidence experimental
cloned [1-3], Northern [1], PCR [4], 454 [5], Illumina [6], CLIPseq [7]
Database links
Predicted targets

References

  1. PubMed ID: 11679671
    An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    "Lau NC, Lim LP, Weinstein EG, Bartel DP"
    "Science (2001) 294:858-862

  2. PubMed ID: 12672692
    The microRNAs of Caenorhabditis elegans
    "Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB, Bartel DP"
    "Genes Dev (2003) 17:991-1008

  3. PubMed ID: 12747828
    MicroRNAs and other tiny endogenous RNAs in C. elegans
    "Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D"
    "Curr Biol (2003) 13:807-818

  4. PubMed ID: 12769849
    Computational and experimental identification of C. elegans microRNAs
    "Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J"
    "Mol Cell (2003) 11:1253-1263

  5. PubMed ID: 17174894
    Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans
    "Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP"
    "Cell (2006) 127:1193-1207

  6. PubMed ID: 19460142
    Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegans development
    Kato M, de Lencastre A, Pincus Z, Slack FJ
    Genome Biol (2009) 10:R54

  7. PubMed ID: 20062054
    Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans
    "Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo GW"
    "Nat Struct Mol Biol (2010) 17:173-179